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Full-Text Articles in Biomedical Engineering and Bioengineering
Methods Of Using Black Bear Parathyroid Hormone, Seth W. Donahue
Methods Of Using Black Bear Parathyroid Hormone, Seth W. Donahue
Michigan Tech Patents
Black bear parathyroid hormone (PTH) and functional fragments thereof are provided. Also provided are methods of using black bear PTH and functional fragments for increasing cAMP in a bone-forming cell; reducing apoptosis in a boneforming cell; decreasing the ratio of expression levels of Bax protein to Bcl-2 protein in a bone-forming cell; increasing the expression level of one or more of a bone matrix protein, a transcriptional activator, or a transcriptional regulator in a bone-forming cell; enhancing bone mineral density, increasing bone mass, decreasing bone loss, or reducing the incidence of bone fractures, or any combination thereof, in a subject; …
Automated Polysomnographic Assessment For Rapid Eye Movement Sleep Behavior Disorder, Joseph W. Burns, Ronald D. Chervin
Automated Polysomnographic Assessment For Rapid Eye Movement Sleep Behavior Disorder, Joseph W. Burns, Ronald D. Chervin
Michigan Tech Patents
Methods and systems for diagnosing or assessing rapid eye movement sleep behavior disorder (RBD). Muscle tone or activity variance during rapid eye movement (REM) and nonrapid eye movement (NREM) sleep intervals of a polysom- nogram are compared. A threshold based on the NREM data is used to identify a subj ect-specific threshold for abnormality in the REM variance. A metric that includes the percentage of REM variance exceeding the threshold relates to RBD.