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Biomedical Engineering and Bioengineering Commons

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Full-Text Articles in Biomedical Engineering and Bioengineering

Designing Biomaterials Using Mussel Adhesive Chemistry, Bruce P. Lee Oct 2017

Designing Biomaterials Using Mussel Adhesive Chemistry, Bruce P. Lee

TechTalks

Marine mussels secrete adhesive proteins that enable them to anchor to surfaces under water. We are exploiting chemistry utilized by mussels to design bioadhesives for tissue repair and wound healing, smart biomaterials for on-demand antipathogenic applications, and smart adhesives that can be turned on and off with externally applied stimuli.


The Subject Librarian Newsletter, Engineering And Computer Science, Fall 2017, Buenaventura "Ven" Basco Aug 2017

The Subject Librarian Newsletter, Engineering And Computer Science, Fall 2017, Buenaventura "Ven" Basco

Libraries' Newsletters

No abstract provided.


Biomechanics And Imaging, Jingfeng Jiang Mar 2017

Biomechanics And Imaging, Jingfeng Jiang

TechTalks

From the perspective of biomechanics, my research is multidisciplinary, bridging the gap between physiology/biology and quantitative sciences. Currently, the applications are on cancer detection and differentiation, therapeutic monitoring, staging liver fibrosis, risk assessment of aneurysm rupture, and more.


Implantable Sensors For Regenerative Medicine, Keat Ghee Ong Mar 2017

Implantable Sensors For Regenerative Medicine, Keat Ghee Ong

TechTalks

In vivo, real-time measurement of local environmental parameters such as strain, pressure, temperature, pH, oxygen tension and specific biomarkers can be valuable for regenerative medicine research and therapies. Wireless implantable sensors are an attractive approach for certain regenerative medicine applications due to its relative simplicity and low cost. Presented here are such two implantable sensors. The first sensor is based on a miniature wireless sensor network that can digitize physical and chemical parameters and continuously stream measurements to a nearby receiver via a 2-way communication protocol. With the incorporation of a strain gauge, this sensor platform was applied to record …


Biodegradable Zinc Vascular Implant Materials, Jeremy Goldman Mar 2017

Biodegradable Zinc Vascular Implant Materials, Jeremy Goldman

TechTalks

Bioabsorbable metal stents are being developed to mitigate the long-term side effects associated with corrosion-resistant stents. A decade-long research with iron (Fe)- and magnesium (Mg)-based stent materials has concluded with little success. Fe produces a voluminous, retained oxide product in the arterial wall, whereas Mg and its alloys corrode too rapidly. A breakthrough in the field of biodegradable metallic stents was made in 2013 in our research team (Drs. Goldman – Biomedical Engineering and Drelich – Materials Science and Engineering) with the introduction of zinc (Zn) and its alloys, which are free of the flaws observed for Fe- and Mg-based …


Low Cost, Adhesion Strength Based Cell Sorter, Emily Burtch, Franck Kamga-Gninzeko, Devin Mair, Sarah Saunders Jan 2017

Low Cost, Adhesion Strength Based Cell Sorter, Emily Burtch, Franck Kamga-Gninzeko, Devin Mair, Sarah Saunders

Capstone Design Expo Posters

In many in vitro experiments, primary cells are harvested from an animal species to undergo experimental manipulation and subsequent analysis. Cell sorters are a luxury to have after cell harvesting to ensure pure populations of cells. Recently, it was discovered that different cell types adhere to cell culture dishes at different strengths. This observation was utilized in the invention of a cell sorting system that sorts cells based on this adhesion strength difference. The resulting system is marketable at under $2000, compared to $50000 plus for current commercially available systems, and is the first commercially-oriented cell adhesion strength based cell …


P1: Using Modified Dean Flow Designs To Increase Mixing Performance, Joshua Clark Jan 2017

P1: Using Modified Dean Flow Designs To Increase Mixing Performance, Joshua Clark

Undergraduate Research Posters 2017

We are using numerical solutions for the Navier-Stokes equations and the concentration - diffusion equation to model fluid flow and reactant distribution in serpentine type channels for micromixers/microreactors development. These mixers exploit centripetal forces on the fluid to induce cross-sectional fluid mixing, aka Dean flows. Various modifications are used to increase the mixing character of these crosssectional flows. We found that the performance of these mixers exceeds that of unmodified channels and we currently assess their performance relative to other state of the art methodologies used to induce mixing on the microscale.


Going Green: Experimental Adaptation Of Scenedesmus Dimorphus To Marine Conditions, Mohammed Khalil Jan 2017

Going Green: Experimental Adaptation Of Scenedesmus Dimorphus To Marine Conditions, Mohammed Khalil

Undergraduate Research Posters 2017

Algae has gained some interest as the need for alternative fuels becomes more pressing. Reliance on fossil fuels is causing our environment and economy harm, and is not sustainable moving forward. Lipid rich algae strains can be used in the production of biofuels, and provide an alternative fuel source. One challenge facing the prospect of algae as a fuel source is that lipid rich algae grows exclusively in freshwater. Considering the scarcity and cost to use freshwater for algae growth, interest has grown in the possibility of adapting lipid rich, freshwater algae to a seawater environment. Seawater can have up …


P2: Implementation Of Groove Based Designs For Engineering Fluid Flow In Micromixers, Tahir Butt Jan 2017

P2: Implementation Of Groove Based Designs For Engineering Fluid Flow In Micromixers, Tahir Butt

Undergraduate Research Posters 2017

Mixing on microscale is important for the development of miniaturized chemical reactors that use small quantities of reactants and allow better control over the reaction conditions and products. Nevertheless, achieving rapid mixing in this type of micro-reactors is challenging due to the lack of turbulence and slow diffusion on the microscale. In this work we implement micromixers designs based on surface groove/ridge patterns targeted at inducing cross-sectional flows that both extend the interface between the different reactants, as well as induce chaotic advection. We discuss the fabrication of these structures using soft-lithography in PDMS employing a mold and their optical …


Development And Verification Of A Mechanical Loading Device For Microfluidics, Stefan Habean, Erin Tesny Jan 2017

Development And Verification Of A Mechanical Loading Device For Microfluidics, Stefan Habean, Erin Tesny

Undergraduate Research Posters 2017

Establishing the role that mechanics play in nerve cell (e.g. neurons) function requires experimental testing. Microfluidic based experiments are commonly used to study neuron growth and function, and studies have found mechanics to play an important role in neuron health. External loads can be applied to a microfluidic device using a motor, which presumably influences the mechanical environment of the cells. While a motor can easily apply known displacements, a “load cell” is necessary to measure corresponding forces. In an existing prototype microfluidic loading device, a load cell was integrated and verified. The manufacturer's calibration of the load cell was …


Skintronics: Wireless, Skin-Wearable Electronics For Monitoring Of Electrocardiogram, Matthew B. Piper, Woon-Hong Yeo, Yongkuk Lee Jan 2017

Skintronics: Wireless, Skin-Wearable Electronics For Monitoring Of Electrocardiogram, Matthew B. Piper, Woon-Hong Yeo, Yongkuk Lee

Undergraduate Research Posters

The ECGs I micro-fabricate are designed to be flexible, stretchable and wireless circuits that can be applied to the skin directly. The device is encased in a conformal, silicon-like substrate, that allows the ECG to be attached with the electrodes. Each electrode has been previously measured and verified that it will be correctly placed for an accurate reading. Prototyping this ECG/electrode device allows the user to mount the prototype directly to the patient without having to attach and wire ten other electrodes. This prototype solves the issue that comes about when a doctor, nurse or emergency medical technician must attach …