Biomedical Engineering and Bioengineering Commons^™

Enhanced Recovery Of Mechanical Function In The Canine Heart By Seeding An Extracellular Matrix Patch With Mesenchymal Stem Cells Committed To A Cardiac Lineage., Glenn Gaudette, Irina Potapova, Sergey Doronin, Damon Kelly, Amy Rosen, Adam Schuldt, Zhongju Lu, Paul Kochupura, Richard Robinson, Michael Rosen, Peter Brink, Ira Cohen

Glenn R. Gaudette

The need to regenerate tissue is paramount, especially for the heart that lacks the ability to regenerate after injury. The urinary bladder extracellular matrix (ECM), when used to repair a right ventricular defect, successfully regenerated some mechanical function. The objective of the current study was to determine whether the regenerative effect of ECM could be improved by seeding the patch with human mesenchymal stem cells (hMSCs) enhanced to differentiate down a cardiac linage. hMSCs were used to form three-dimensional spheroids. The expression of cardiac proteins was determined in cells exposed to the spheroid formation and compared with nonmanipulated hMSCs. To …

Research For Propanediol, Chuen-Tat Kang

Kang Chuen Tat (江俊达)

First and foremost, I would like to express my deepest gratitude to all parties involve in the contribution of the contents of the book. Without their efforts this book publication will never be made possible. This book summarizes the research experience of Chuen-Tat Kang comprehensively from year 2005 in Australia. Most portion of the book describes the biocatalysis research held in Swinburne University of Technology (www.swin.edu.au) and Commonwealth Scientific and Industrial Research Organization (CSIRO) Australia (www.csiro.gov.au) during the postgraduate doctorate studies in year 2005. Portion of the content of the scientific research experience could be viewed at the website http://chuentat.tripod.com. …

Analytical Study Of Blood Flow With Periodic Body Acceleration In The Presence Of Magnetic Field, Dr. Anil Kumar

Dr. Anil Kumar

In this paper we consider a human body is quite often subjected to the acceleration in the magnetic e#11;ects. The induced magnetic #12;eld is neglected. To account such acceleration can generate signi#12;cant e#11;ects on blood circulation depending on the con#12;guration and geometry of the blood arteries. The current study is related to mathematical model of study of blood ow in presence of magnetic e#11;ects subjected to externally imposed periodic body acceleration. By using the #12;nite Hankel Transforms, an exact solution of steady ow of blood as an incompressible, couple stress uid has been obtained. The results have been compared with …

Agarose And Methylcellulose Hydrogel Blends For Nerve Regeneration Applications, Benton C. Martin

Benton C. Martin

No abstract provided.

Lend Me Your Arms: The Use And Implications Of Humancentric Rfid, Amelia Masters, Katina Michael

Professor Katina Michael

Recent developments in the area of RFID have seen the technology expand from its role in industrial and animal tagging applications, to being implantable in humans. With a gap in literature identified between current technological development and future humancentric possibility, little has been previously known about the nature of contemporary humancentric applications. By employing usability context analyses in control, convenience and care-related application areas, we begin to piece together a cohesive view of the current development state of humancentric RFID, as detached from predictive conjecture. This is supplemented by an understanding of the market-based, social and ethical concerns which plague …

Writing Research Proposal: Literature Review And Database Search, Mamoudou H. Dicko Prof.

Pr. Mamoudou H. DICKO, PhD

Synthesis And Characterization Of Biodegradable Elastomeric Polyurethane Scaffolds Fabricated By The Inkjet Technique.”, Changhong Zhang, Xuejun Wen, Narendra Vyavahare, Thomas Boland

Thomas Boland

Biodegradable polyurethanes (PUs) were synthesized from methylene di-p-phenyl-diisocyanate (MDI), polycaprolactone diol (PCL-diol) and N,N-bis (2-hydorxyethyl)-2-aminoethane-sulfonic acid (BES), serving as a hard segment, soft segment and chain extender, respectively. MDI was chosen due to its reactivity and wide application in synthesis of biomedical polyurethanes due to its reactivity; PCL-diol was chosen because of its biodegradability; and BES was chosen because it allowed the introduction sulfonic acid groups onto the polymer chains. We evaluated the polyurethanes' degradation rate, mechanical properties, hydrophilicity, antithrombogenecity, and ability to support fibroblast cell attachment and growth by comparing with polymers having a 2,2-(methylimino)diethanol (MIDE) chain extender. Mechanical …

Loading Dependent Swelling And Release Properties Of Novel Biodegradable, Elastic And Environmental Stimuli-Sensitive Polyurethanes, Changhong Zhang, Kejia Zhao, Tj Hu, Xiaofeng Cui, Nathan Brown, Thomas Boland

Thomas Boland

A novel degradable, elastic, anionic, and linear polyurethane was synthesized from hexamethylene diisocyanate, polycaprolactone diol, and a bicine chain extender. The chemical structure, mechanical properties, degradation rate, and swelling ratio were characterized by comparing the polymer with a polyurethane containing a 2,2-(methylimino) diethanol chain extender. Due to the incorporation of negatively charged carboxyl side groups, the bicine extended polymers exhibited higher micro-phase separation, better mechanical properties in dry condition, and better sensitivity to environmental stimuli than controls, as demonstrated by its high swelling ratio at elevated pH, lower ionic strength, or higher temperature. The swelling ratio of membranes showed reversible …

Recent Development Of The Homotopy Perturbation Method, Ji-Huan He

Ji-Huan He

The homotopy perturbation method is extremely accessible to non-mathematicians and engineers. The method decomposes a complex problem under study to a series of simple problems that are easy to be solved. This note gives an elementary introduction to the basic solution procedure of the homotopy perturbation method. Particular attention is oaid to constructing a suitable homotopy equation.