Engineering Commons^™

Bme Stats Winter 2006, Department Of Biomedical Engineering, Florida International University

STATS

No abstract provided.

Disminución En La Cantidad Y Calidad De La Película Lagrimal En Cocineros De Asaderos De Pollos Después De La Jornada Laboral En El Centro De Bogotá, Ingrid Astrid Jiménez Barbosa, Juan Sebastián Bejarano Usaquén, Viviana Barón Calderón

Ciencia y Tecnología para la Salud Visual y Ocular

Se realizó un estudio descriptivo que tenía por objetivo principal determinar los cambios en la calidad y cantidad de la película lagrimal de los cocineros que laboran en asaderos de pollos en la zona centro de Bogotá expuestos a factores de riesgo como humo y temperaturas altas (del asador). Se tomaron dos grupos: uno control (no expuesto a los factores de riesgo: meseros) y uno experimental (expuesto a los factores de riesgo: los cocineros de pollos); ambos grupos contaban con 20 individuos de género masculino, quienes no presentaban patologías oculares, su edad promedio fue de 27 años. A estos sujetos …

Estudio In Vitro De La Capacidad De Proliferación De Candida Albicans En Diferentes Materiales De Lentes De Contacto Blandos, Liliana Zambrano, Claudia M. Parra G., Miriam Teresa Mayorga

Ciencia y Tecnología para la Salud Visual y Ocular

Debido a la creciente importancia que tiene el uso de lentes de contacto blandos para corregir ametropías a nivel mundial y en la población colombiana, sumado a la capacidad de la levadura Candida albicans de producir enfermedades oculares por el uso de los mismos, llegando a ser uno de los principales agentes infecciosos; en este estudio se evaluó la capacidad de Candida albicans de proliferar en 5 diferentes materiales de lentes de contacto blandos hidrofílicos, tres de ellos de hidrogel (Alphafilcon A, Omafilcon A, Polymacon) y dos de hidrogel silicona (Balafilcon A y Lotrafilcon A). Se encontró que la levadura …

A Modified Hodgkin–Huxley Model, Ji-Huan He

Ji-Huan He

A modified Hodgkin–Huxley model is suggested by taking into account the size effect of ionic channels.

An Evaluation Of Osteoporosis Prevalence In Spinal Cord Disabled Veterans, Hossein Gholizadeh

Hossein Gholizadeh

DANESHVAR MEDICINE; DECEMBER 2006-JANUARY 2007; 14(66);37-44. AN EVALUATION OF OSTEOPOROSIS PREVALENCE IN SPINAL CORD DISABLED VETERANS SHOJAEI H.,SOROUSH M.R.,MODIRIAN E.,GHOLIZADEH H. Introduction: Osteoporosis and bone fracture risk due to decrease in bone mineral density is known as one of the most important complications of chronic spinal cord injuries (SCI). It also is a major health problem among the patients in SCI society. Although immobilization, old age, menopause and some comorbiditing, are major causes, other important factors also should be taken into consideration. Materials & Method: In this cross-sectional study, 132 veterans with SCI (mean of age 37.4 years), underwent dual-energy …

Heat And Mass Transfer (Baehr And Stephan), Dr Alireza Zolfaghari

Dr Alireza Zolfaghari

No abstract provided.

A Heat Transfer Textbook (Lienhard), Dr Alireza Zolfaghari

Dr Alireza Zolfaghari

No abstract provided.

Application Of E-Infinity Theory To Biology, Ji-Huan He

Ji-Huan He

Albert Einstein combined continuous space and time into his special relativity, El-Naschie discovered the transfinite discontinuity of space–time in his E-infinity theory where infinity of dimensions was created. We find a partner of both space–time and E-infinity in biology. In our theory, the number of cells in an organism endows an additional dimension in biology, leading to explanation of many complex phenomena.

Application Of E-Infinity Theory To Biology, Ji-Huan He

Ji-Huan He

Albert Einstein combined continuous space and time into his special relativity, El-Naschie discovered the transfinite discontinuity of space–time in his E-infinity theory where infinity of dimensions was created. We find a partner of both space–time and E-infinity in biology. In our theory, the number of cells in an organism endows an additional dimension in biology, leading to explanation of many complex phenomena.

Quantitative Measurement Of The Brã¶Nsted Acid Sites In Solid Acids: Toward A Single-Site Design Of Mo-Modified Zsm-5 Zeolite, Jean-Philippe Tessonnier, Benoit Louis, Stephane Walspurger, Jean Sommer, Marc-Jacques Ledoux, Cuong Pham-Huu

Jean-Philippe Tessonnier

On the basis of our previous H/D exchange studies devoted to the quantification of the number of Bro¨nsted acid sites in solid acids, we report here an innovative approach to determine both the amount and the localization of Mo atoms inside the Mo/ZSM-5 catalyst, commonly used for the methane dehydroaromatization reaction. The influence of Mo introduction in the MFI framework was studied by means of BET, X-ray diffraction, 27Al magic angle spinning NMR, NH3 temperature-programmed desorption, and H/D isotopic exchange techniques. A dependence was found between the decrease of acidic OH groups and the Mo content. Depending on the Si/Al …

A Numerical Acoustic Fluid-Structure Simulation Of Therapeutic Ultrasound Angioplasty, Graham Gavin, Finbar Dolan, M.S J. Hashmi, Garrett Mcguinness

Conference Papers

INTRODUCTION Therapeutic ultrasound angioplasty is the delivery of high amplitude ultrasonic displacements to the distal-tip of small diameter wire waveguides with the goal of disrupting atherosclerotic plaques. This is a minimally invasive procedure that may have potential' in the treatment of complicated chronic total occlusions. The disruption of plaque is due to direct contact ablation and also cavitation, pressure waves and acoustic streaming in the fluid surrounding the vibrating waveguide distal-tip [1]. Cavitation appears to play a major role and some authors have suggested that plaque ablation is only evident above the cavitation threshold [2]. Makin and Everbach [3] performed …

Development Of A Software Application To Extract The Features Of Normal Respiratory Sounds From The Lungs And The Trachea, Ranjani Sabarinathan

Theses and Dissertations

Auscultation has been widely regarded as one of the most important noninvasive diagnostic tools for clinical diagnosis of the respiratory tract. The purpose of this thesis was to develop a software application capable of extracting the key features of respiratory sound signals from the lungs and trachea of healthy persons. The efficacy of the program was evaluated by the verification of the important features of the sound signals from the left and right lungs and the trachea such as 1) right and left lung symmetry and 2) dissimilarity between the trachea and both lungs. The program was developed in LabView …

Detection, Identification And Classification Of Suck, Swallow And Breathing Activity In Premature Infants During Bottle-Feeding, Fedra Adnani

Theses and Dissertations

Prematurity, especially if extreme, is one of the leading causes of problems and/or death after delivery. Among all the problems encountered by premature infants, feeding difficulties are very common. Many premature infants are fed intravenously at first, and they progress to milk feedings provided by a tube passed into the stomach. At around 34 weeks of gestation, premature infants should be able to breastfeed or take a bottle. At the same time such premature infants are usually faced with difficulty making the transition from tube-feeding to full oral feeding. In this study three physiological measurements of premature infants including sucking, …

Evaluation Of Prototype Cell Delivery Catheters Using Agarose Gel And Cell Culture Experiments, Sagar Panse

Theses and Dissertations

Neurodegenerative diseases and brain tumors affect millions of patients worldwide and are associated with significant morbidity and mortality. The blood brain barrier constitutes a major obstacle to delivery of therapeutic agents administered systemically for treating these disorders. Intracranial drug delivery provides a novel way of bypassing the blood brain barrier and achieving high concentration of therapeutic agents in the brain while avoiding systemic side effects. However damage to tissues during insertion of catheters, release of air in the brain and consequent backtracking of dye are some disadvantages with this mode of treatment. We evaluated prototype cell delivery catheters (each with …

Intracellular Signaling Networks In The Immune Response: Pathways Activated By Interleukin-2 And-4 Receptors And Their Roles In T Cell Proliferation, Kristen K. Comfort

Chemical and Materials Engineering Faculty Publications

Cells sense and respond to chemical and physical stimuli through signal transduction pathways, which mediate cell proliferation, differentiation, migration, and survival. The cytokines interleukin-2 (IL-2) and interleukin-4 (IL-4) are key regulators of the adaptive immune system, particularly influencing the clonal expansion and differentiation of T cells. At least in culture, both synergistic and antagonistic effects of IL-2 and -4 co-stimulation have been reported; the antagonism, when observed, is thought to arise from the utilization of a common subunit shared by IL-2 and IL-4 receptors. We have sought to characterize IL-2 and IL-4 signaling at the level of intracellular pathways activated …

Design Of Near-Optimal Waveforms For Chest And Abdominal Compression And Decompression In Cpr Using Computer-Simulated Evolution, Charles F. Babbs

Weldon School of Biomedical Engineering Faculty Publications

Objective: To discover design principles underlying the optimal waveforms for external chest and abdominal compression and decompression during cardiac arrest and CPR. Method: A 14-compartment mathematical model of the human cardiopulmonary system is used to test successive generations of randomly mutated external compression waveforms during cardiac arrest and resuscitation. Mutated waveforms that produced superior mean perfusion pressure became parents for the next generation. Selection was based upon either systemic perfusion pressure (SPP=thoracic aortic minus right atrial pressure) or upon coronary perfusion pressure (CPP=thoracic aortic pressure minus myocardial wall pressure). After simulations of 64,414 individual CPR episodes, 40 highly evolved waveforms …

A New Biomechanical Head Injury Criterion, Charles F. Babbs

Weldon School of Biomedical Engineering Faculty Publications

This paper presents a new analysis of the physics of closed head injury caused by intense acceleration of the head. At rest a 1 cm gap filled with cerebrospinal fluid (CSF) separates the human brain from the skull. During impact whole head acceleration induces artificial gravity within the skull. Because its density differs slightly from that of CSF, the brain accelerates, strikes the inner aspect of the rigid skull, and undergoes viscoelastic deformation. Analytical methods for a lumped parameter model of the brain predict internal brain motions that correlate well with published high-speed photographic studies. The same methods predict a …

Hmg-Coa Reductase Inhibitors Act Synergistically With Ucn-01 Through Ras Inhibition, Payal Khanna

Theses and Dissertations

The primary objective of this study is to elucidate the mechanism by which the reagent UCN-01 induces apoptosis when administered to leukemia cells along with HmG-CoA reductase inhibitors, mainly the statins. In this study, we demonstrated that exposure of leukemia cell lines to lovastatin (20 uM, 18 hours) and UCN-01 (100 nM, 18 hours) resulted in mitochondria dysfunction, procaspase 3 and 9 cleavage, and PAW degradation along with marked cytochrome C release and apoptosis. Although similar molecular mechanisms have not yet been confirmed in other cancers, our hypothesis holds that enhanced apoptotic effects of UCN-01 are due in part to …

A Numerical Acoustic Fluid-Structure Model Of A Therapeutic Ultrasound Angioplasty Device, Graham Gavin, M.S. J. Hashmi, Finbar Dolan, Garrett Mcguinness

Conference Papers

Ultrasonic angioplasty involves the use of ultrasonic vibrations delivered to the distal-tip of small diameter wire waveguides and is an emerging technology the may have potential use in the treatment of complicated atherosclerotic plaques during cardiovascular surgery. Complicated plaques, including chronic total occlusions and calcified lesions, seriously reduce success rates during standard intervention involving guidewire access, followed by balloon dilation or stent delivery. The large amplitude (0-150 μm) wire waveguide distal-tip displacements in the low-frequency ultrasonic (18-45 kHz) range have been shown to disrupt plaque material by direct contact ablation and cavitation, acoustic streaming and pressure wave components in adjacent …

Scaffold Permeability As A Means To Determine Fiber Diameter And Pore Size Of Electrospun Fibrinogen, Scott Allen Sell

Theses and Dissertations

The purpose of this study was to construct a flowmeter that could accurately measure the hydraulic permeability of electrospun fibrinogen scaffolds, providing insight into the transport properties of electrospun scaffolds while making the measurement of their topographical features (fiber and pore size) more accurate. Three different concentrations of fibrinogen were used (100, 120, and 150mg/ml) to create scaffolds with three different fiber diameters and pore sizes. The fiber diameters and pore sizes of the electrospun scaffolds were analyzed through scanning electron microscopy and image analysis software. The permeability of each scaffold was measured and used to calculate permeability-based fiber diameters …

Computational Modeling To Predict Mechanical Function Of Joints: Validations And Applications Of Lower Leg Simulations, Peter C. Liacouras

Theses and Dissertations

Computational models of musculoskeletal joints and limbs can provide useful information about joint mechanics. Validated models can be used as a predictive device for understanding joint function and serve as a clinical tool for predicting the outcome of surgical procedures. A new computational modeling approach was developed for simulating joint kinematics that are dictated by bone/joint anatomy, ligamentous constraints, and applied loading.Three-dimensional computational models of the lower leg were created. Model development involved generating three-dimensional surfaces from CT images, followed by importing these surfaces into SolidWorks and COSMOSMotion. ThroughSolidWorks and COSMOSMotion, each bone surface was created into a solid object …

Nanoelectropulse-Driven Membrane Perturbation And Small Molecule Permeabilization, P. Thomas Vernier, Yinghua Sun, Martin A. Gundersen

Bioelectrics Publications

Background
Nanosecond, megavolt-per-meter pulsed electric fields scramble membrane phospholipids, release intracellular calcium, and induce apoptosis. Flow cytometric and fluorescence microscopy evidence has associated phospholipid rearrangement directly with nanoelectropulse exposure and supports the hypothesis that the potential that develops across the lipid bilayer during an electric pulse drives phosphatidylserine (PS) externalization.

Results
In this work we extend observations of cells exposed to electric pulses with 30 ns and 7 ns durations to still narrower pulse widths, and we find that even 3 ns pulses are sufficient to produce responses similar to those reported previously. We show here that in contrast to …

Controlled Braking Scheme For A Wheeled Walking Aid, Eugene Coyle, Aidan O'Dwyer, Eileen Young, Kevin Sullivan, A. Toner

Conference papers

A wheeled walking aid with an embedded controlled braking system is described. The frame of the prototype is based on combining features of standard available wheeled walking aids. A braking scheme has been designed using hydraulic disc brakes to facilitate accurate and sensitive controlled stopping of the walker by the user, and if called upon, by automatic action. Braking force is modulated via a linear actuating stepping motor. A microcontroller is used for control of both stepper movement and for supervisory control. An encoder is used to supervise walker movement in terms of time, distance and speed.

Accidentalidad Ocular En Los Talleres Del Instituto Técnico Industrial Piloto De Bogota Durante Los Años 2001 A 2003, Ingrid Astrid Jiménez Barbosa

Ciencia y Tecnología para la Salud Visual y Ocular

Este trabajo pretende realizar un diagnóstico de la accidentalidad ocular de los estudiantes que rotan por los talleres del Instituto Técnico Industrial Piloto de Bogotá: para ello inicialmente se recopilaron y revisaron las estadísticas de accidentalidad de tres años (2001-2003) identificando el taller más afectado, el grado o curso y el número de accidentes reportados. Se concluyó que los talleres de mecánica industrial, mecánica automotriz y metalistería son los que mayor riesgo representan para la salud ocular y visual de los estudiantes; ya que allí se presentó el mayor número de accidentes. Los grados sexto, séptimo, octavo y noveno se …

El Desarrollo Del Sistema General De Seguridad Social En Salud Desde La Implementación De La Ley 100 De 1993 A La Fecha (Una Opinión Libre), Wilson Giovanni Jiménez Barbosa

Ciencia y Tecnología para la Salud Visual y Ocular

El presente artículo busca adelantar un análisis libre de la evolución del desarrollo del Sistema General de Seguridad Social en Salud desde su implementación mediante la promulgación de la Ley 100 de 1993 y las posteriores normas que la han complementado. En su primera parte, realiza un breve recorrido por el sistema, tomando como puntos de referencia los principios fundamentales establecidos para el mismo, tanto en la constitución nacional, como dentro de la misma Ley 100, para luego continuar con una visión crítica de la misma, buscando determinar las principales fallas y puntos álgidos por donde la corrupción la ha …

Editorial, Jairo H. García Touchie

Ciencia y Tecnología para la Salud Visual y Ocular

No abstract provided.

Efecto Del Fumarato De Ketotifeno Tópico Sobre La Concentración De Ige Total En Lágrimas Y La Expresión De Hla-Dr En Pacientes Con Conjuntivitis Alérgica, Hilda Henny Herrera, Pilar Prada, Martha Rodríguez, Alberto Rojas

Ciencia y Tecnología para la Salud Visual y Ocular

La conjuntivitis alérgica es una hipersensibilidad tipo I o inmediata mediada por la IgE y su efecto sobre la liberación y activación de mediadores inflamatorias por los mastocitos. El objetivo del estudio fue determinar la presencia de sintomatología y concentración de IgE total en lágrimas antes y después del tratamiento con fumarato de ketotifeno en pacientes con conjuntivitis alérgica. Métodos: 12 pacientes con conjuntivitis alérgica que acudieron al Instituto de Investigaciones Optometricas de la Universidad de La Salle, se les realizó examen oftalmológico y determinación de IgE total en lágrimas. A estos pacientes se les trató con zaditen 0,025%, 1 …

Relación Entre Los Accidentes Oculares Ocurridos En Los Talleres Del Instituto Técnico Industrial Piloto De Bogotá Y Los Modelos Mentales Y Niveles De Conciencia De Los Estudiantes, Ingrid Astrid Jiménez Barbosa

Ciencia y Tecnología para la Salud Visual y Ocular

Tomando como referente la teoría del enfoque humanista en Salud Ocupacional y para conocer las percepciones de los estudiantes que rotan por los talleres del Instituto Técnico Industrial Piloto de Bogotá, frente a los factores individuales que pueden desencadenar accidentes visuales se realizó una encuesta con cuatro preguntas abiertas, a una muestra de 60 estudiantes, para determinar los modelos mentales más predominantes y sus niveles de conciencia frente a los accidentes. Para el tratamiento de esta información se hizo un análisis cualitativo basado en la triangulación de la información utilizando categorías y subcategorías de las respuestas; además, se aplicó un …

El Pterigio, Una Patología Relevante En La Población Del Valle De San Diego De Ubaté, Gina Sorel Rubio Rincón, Claudia Xiomara Amaya Perozzo, Giovanna Muñoz-Devia, Isabel López-López

Ciencia y Tecnología para la Salud Visual y Ocular

En esta investigación se estableció la prevalencia de pterigio según edad, género, ocupación y zona de permanencia de los pobladores del Valle de San Diego de Ubaté, durante el periodo comprendido entre julio de 2005 y enero de 2006. Se estudiaron 897 pacientes que asistieron a la consulta de optometría y oftalmología del Hospital El Salvador de Ubaté. Para los efectos de esta investigación, el método de recolección de datos fue el de recopilación de historias clínicas. Como resultado, se observó que la prevalencia de pterigio, fue del 40,31% en el grupo de edad entre 20-40 años, del 61,47% en …

Conocimiento Y Aplicación De La Norma De Detección De Alteraciones De La Agudeza Visual, Jorge Giovanni Vargas Velasco

Ciencia y Tecnología para la Salud Visual y Ocular

La resolución número 412 de 2000 establece las actividades, procedimientos e intervenciones de promoción y prevención en salud, las normas de atención para el desarrollo de las acciones de protección específica, detección temprana y atención de enfermedades de interés en salud pública, una de las cuales se denomina Detección de Alteraciones de la Agudeza Visual, en la cual se contemplan las técnicas apropiadas para la toma de visión de lejos y de cerca. Se realizó una investigación que determinó el grado de conocimiento de la norma técnica para la detección de alteraciones de la agudeza visual por parte de los …