Open Access. Powered by Scholars. Published by Universities.®
- Institution
-
- University of Nebraska - Lincoln (654)
- Marquette University (640)
- California Polytechnic State University, San Luis Obispo (529)
- Engineering Conferences International (510)
- Selected Works (426)
-
- Universidad de La Salle (425)
- Utah State University (407)
- New Jersey Institute of Technology (394)
- Purdue University (391)
- Western University (372)
- Old Dominion University (349)
- Virginia Commonwealth University (281)
- Wright State University (274)
- University of Arkansas, Fayetteville (258)
- University of Kentucky (257)
- Clemson University (224)
- City University of New York (CUNY) (189)
- Missouri University of Science and Technology (185)
- Cleveland State University (184)
- SelectedWorks (174)
- Washington University in St. Louis (171)
- Michigan Technological University (163)
- University of Tennessee, Knoxville (161)
- Technological University Dublin (148)
- University of South Florida (145)
- Florida International University (136)
- Santa Clara University (130)
- Wayne State University (127)
- Louisiana Tech University (111)
- Boise State University (109)
- Keyword
-
- Biomechanics (184)
- Tissue engineering (124)
- Biomaterials (112)
- Biomedical Sciences (106)
- Microfluidics (97)
-
- Humans (93)
- Applied sciences (92)
- Cancer (87)
- Biomedical Engineering (83)
- Biomedical engineering (82)
- Bone (79)
- Electrospinning (76)
- Nanoparticles (75)
- Department of Biomedical, Industrial & Human Factors Engineering (72)
- Bioengineering (70)
- Drug delivery (69)
- Daniel Felix Ritchie School of Engineering and Computer Science (68)
- Machine learning (68)
- Rehabilitation (64)
- Gait (63)
- Ultrasound (63)
- Department of Biomedical Engineering (62)
- Imaging (62)
- Tissue Engineering (62)
- Engineering (58)
- Kinematics (54)
- Biomedical (53)
- EEG (53)
- Finite element analysis (51)
- Hydrogel (51)
- Publication Year
- Publication
-
- Biomedical Engineering Faculty Research and Publications (525)
- Theses and Dissertations (455)
- Ciencia y Tecnología para la Salud Visual y Ocular (416)
- Theses (336)
- Electronic Thesis and Dissertation Repository (312)
-
- Biological Systems Engineering: Papers and Publications (295)
- Master's Theses (253)
- Cell Culture Engineering XV (246)
- Doctoral Dissertations (237)
- Electronic Theses and Dissertations (237)
- Biomedical Engineering (232)
- Browse all Theses and Dissertations (181)
- Cells and Materials (166)
- Chemical and Biochemical Engineering Faculty Research & Creative Works (155)
- McKelvey School of Engineering Theses & Dissertations (146)
- Bioelectrics Publications (143)
- USF Tampa Graduate Theses and Dissertations (141)
- The Summer Undergraduate Research Fellowship (SURF) Symposium (127)
- Weldon School of Biomedical Engineering Faculty Publications (127)
- ETD Archive (115)
- Graduate Theses and Dissertations (112)
- All Dissertations (107)
- Masters Theses (96)
- Publications and Research (92)
- Biomedical, Industrial & Human Factors Engineering Faculty Publications (91)
- Honors Theses (91)
- All Theses (88)
- Biomedical Engineering Undergraduate Honors Theses (87)
- All Graduate Theses and Dissertations, Spring 1920 to Summer 2023 (86)
- FIU Electronic Theses and Dissertations (85)
- Publication Type
Articles 9481 - 9510 of 10762
Full-Text Articles in Engineering
Predicted Gait Modifications To Reduce The Peak Knee Adduction Torque, B. J. Fregly, K. L. Rooney, Jeffrey A. Reinbolt
Predicted Gait Modifications To Reduce The Peak Knee Adduction Torque, B. J. Fregly, K. L. Rooney, Jeffrey A. Reinbolt
Jeffrey A. Reinbolt
No abstract provided.
Sequential Labelling And Acoustic Emission Analysis Of Damage Occurring In Cortical Bone During Indentation Cutting, Ger Reilly, Ashkan Safari, David Taylor, Brendan Mccormack
Sequential Labelling And Acoustic Emission Analysis Of Damage Occurring In Cortical Bone During Indentation Cutting, Ger Reilly, Ashkan Safari, David Taylor, Brendan Mccormack
Conference Papers
When a surgeon uses a wedge shaped blade or an osteotome to cut cortical bone during an operative procedure the bone will fail by a process of microcracking and primary crack propagation. It has previously been observed that crack propagation is dependent on the direction of cutting relative to the main axis of the bone. It has also been observed that microcracks occurring during fracture release acoustic signals that facilitate real-time monitoring of a cutting process. In these novel studies, we labelled damage accumulation during cutting of cortical bone using sequential chelating dyes and we correlated recorded AE signals during …
Creation Of Patient-Specific Dynamic Models From Three-Dimensional Movement Data Using Optimization, Jeffrey A. Reinbolt, B. J. Fregly
Creation Of Patient-Specific Dynamic Models From Three-Dimensional Movement Data Using Optimization, Jeffrey A. Reinbolt, B. J. Fregly
Jeffrey A. Reinbolt
No abstract provided.
Managing Phosphorus In Beef Feeding Operations, William F. Kissinger, Richard K. Koelsch, Galen E. Erickson, Terry J. Klopfenstein
Managing Phosphorus In Beef Feeding Operations, William F. Kissinger, Richard K. Koelsch, Galen E. Erickson, Terry J. Klopfenstein
Department of Biological Systems Engineering: Conference Presentations and White Papers
A commercial feedlot study was conducted to determine manure nutrient flow in six feedlots representing 6,366 cattle. On average, cattle involved in this summary were yearlings (BW = 353 kg) and gained 183 kg over 123 d. It was calculated that 11.5% of the feed nitrogen and 16.9% of the feed phosphorus was retained by the animal with the remaining nutrients excreted. On average, 25.6 kg of N and 4.1 kg of P (DM basis) were excreted per fed beef animal. On average, 887 kg total manure (solids and water) were removed per finished animal (7.2 kg/animal/d) averaging 73% total …
Integrating Animal Feeding Strategies Into Cnmp Processes: Role Of Updated Asae Standard D384.2, Richard K. Koelsch, W. Powers, A. L. Sutton
Integrating Animal Feeding Strategies Into Cnmp Processes: Role Of Updated Asae Standard D384.2, Richard K. Koelsch, W. Powers, A. L. Sutton
Department of Biological Systems Engineering: Conference Presentations and White Papers
This paper introduces the new ASAE Standard D384.2, Manure Production and Characteristics. This new standard provides an equation-based approach that integrates dry matter and nutrient intake as well as animal performance into the final estimate of total solids, nitrogen, and phosphorus excretion for seven livestock and poultry species. The manure excretion estimates of the new standard are compared with the past ASAE standard as well as other commonly used reference values for three specie groups. Significant differences in excretion are common with the new standard compared to past standards. The paper also details examples of how common industry variations in …
A New Application For Fine Ground Rubber In The Control Of Odors From Livestock Manure Storage Structures, Lakshmi Koppolu, Richard K. Koelsch, Dennis D. Schulte, Crystal Powers, Dwaine Bundy
A New Application For Fine Ground Rubber In The Control Of Odors From Livestock Manure Storage Structures, Lakshmi Koppolu, Richard K. Koelsch, Dennis D. Schulte, Crystal Powers, Dwaine Bundy
Department of Biological Systems Engineering: Conference Presentations and White Papers
The purpose of this project was to quantify the odor and gas emission benefits of a fine ground rubber cover on laboratory scale manure storage units and to evaluate the ability of a fine ground rubber cover applied to a commercial swine manure storage unit to remain intact and functional over an extended period of time. A three-inch cover of fine ground rubber reduced odors by 77 to 99 percent from the manure storage tanks over a six-week period. However, consistent reductions of NH3 emissions were not observed and H2S emissions from all manure storage treatments were …
Elastic Waves Push Organic Fluids From Reservoir Rock, Igor A. Beresnev, R. Dennis Vigil, Wenqing Li, Wayne D. Pennington, Roger M. Turpening, Pavel P. Iassonov, Robert P. Ewing
Elastic Waves Push Organic Fluids From Reservoir Rock, Igor A. Beresnev, R. Dennis Vigil, Wenqing Li, Wayne D. Pennington, Roger M. Turpening, Pavel P. Iassonov, Robert P. Ewing
R. Dennis Vigil
Elastic waves have been observed to increase productivity of oil wells, although the reason for the vibratory mobilization of the residual organic fluids has remained unclear. Residual oil is entrapped as ganglia in pore constrictions because of resisting capillary forces. An external pressure gradient exceeding an ‘‘unplugging’’ threshold is needed to carry the ganglia through. The vibrations help overcome this resistance by adding an oscillatory inertial forcing to the external gradient; when the vibratory forcing acts along the gradient and the threshold is exceeded, instant ‘‘unplugging’’ occurs. The mobilization effect is proportional to the amplitude and inversely proportional to the …
Electromagnetic Measurement Of Spinal Curvature, Ronan Fitzmaurice, Ted Burke, Annraoi De Paor
Electromagnetic Measurement Of Spinal Curvature, Ronan Fitzmaurice, Ted Burke, Annraoi De Paor
Conference Papers
In this paper, we describe an original mathematical technique for calculating the position and orientation of an electromagnetic coil from a minimum of four collinear magnetic field measurements. This problem arose in the development of a system for evaluating the efficacy of inflatable back rafts designed to mitigate complications that arise from the immobilisation of patients with suspected spinal injuries on spinal boards during transport to hospital. Electromagnetic markers are attached to points of interest on the back of an immobilised test subject. Spinal curvature is then measured by passing a magnetometer underneath the board.
Modeling, Design, And Validation Of Fluorescent Spherical Enzymatic Glucose Microsensors Using Nanoengineered Polyelectrolyte Coatings, Jonathan Quincy Brown
Modeling, Design, And Validation Of Fluorescent Spherical Enzymatic Glucose Microsensors Using Nanoengineered Polyelectrolyte Coatings, Jonathan Quincy Brown
Doctoral Dissertations
In this dissertation, the modeling, design, and function of fluorescent spherical enzymatic microsensors for minimally-invasive diabetic monitoring are described. The devices reported herein are novel and their experimental construction and theoretical analysis have not been previously reported, thus laying the foundation for an intensive set of studies. These sensors are based on the encapsulation of an enzymatic fluorescent assay for glucose within hydrogel alginate microspheres with diameters on the order of tens of microns, which are of the appropriate size for intradermal implantation. A novel feature of these sensors is the use of multifunctional nanoengineered ultrathin multilayer polyelectrolyte coatings on …
Organization And Signal Processing Of The Descending Tracts In The Cervical Spinal Cord, Yanmei Tie
Organization And Signal Processing Of The Descending Tracts In The Cervical Spinal Cord, Yanmei Tie
Doctoral Dissertations
This dissertation addresses the research for the development of spinal cord-computer interface (SCCI). The main objective of SCCI is to generate voluntary motor control signals for individuals with spinal cord injury (SCI).
In the neuroscience aspect, organization of the fibers in the descending tracts of the dorsolateral funiculus of the cervical spinal cord was investigated in cats. The spinal cord was penetrated with silicon substrate microelectrodes at 400 μm intervals in the medio-lateral direction at the C5/C6 and C6/C7 segmental borders. The stimulus consisted of a 20 ms train of charge-balanced biphasic pulses at 330 Hz. The evoked activities from …
Substrate-Mediated Gene Delivery For Assessment Of Signal Transduction Pathways In Cancer Cells, Angela K. Pannier, Zain Bengali, Eric A. Ariazi, V. Craig Jordan, Lonnie D Shea
Substrate-Mediated Gene Delivery For Assessment Of Signal Transduction Pathways In Cancer Cells, Angela K. Pannier, Zain Bengali, Eric A. Ariazi, V. Craig Jordan, Lonnie D Shea
Department of Biological Systems Engineering: Conference Presentations and White Papers
Gene delivery has the potential to be used in diagnostic applications, specifically to investigate cellular signal transduction pathways responsible for disease. Analysis of multiple pathways or genes in a parallel format can be achieved using a transfected cell array, a high throughput approach to correlate gene expression with functional cell responses, based on gene delivery from a substrate that supports cell adhesion. Substrate-mediated gene delivery functions by self-assembling DNA with nonviral vectors, resulting in positively charged complexes that can interact with a biomaterial or substrate. Cells cultured on the substrate are exposed to elevated DNA concentrations within the local microenvironment, …
Interaction Of Visual And Proprioceptive Feedback During Adaptation Of Human Reaching Movements, Robert A. Scheidt, Michael A. Conditt, Emanuele L. Secco, Ferdinando A. Mussa-Ivaldi
Interaction Of Visual And Proprioceptive Feedback During Adaptation Of Human Reaching Movements, Robert A. Scheidt, Michael A. Conditt, Emanuele L. Secco, Ferdinando A. Mussa-Ivaldi
Biomedical Engineering Faculty Research and Publications
People tend to make straight and smooth hand movements when reaching for an object. These trajectory features are resistant to perturbation, and both proprioceptive as well as visual feedback may guide the adaptive updating of motor commands enforcing this regularity. How is information from the two senses combined to generate a coherent internal representation of how the arm moves? Here we show that eliminating visual feedback of hand-path deviations from the straight-line reach (constraining visual feedback of motion within a virtual, “visual channel”) prevents compensation of initial direction errors induced by perturbations. Because adaptive reduction in direction errors occurred with …
Characterization Of Mismatch Between Behavioral Stimuli And Frmi Data Using The Kalman Filter, Jason Steffener
Characterization Of Mismatch Between Behavioral Stimuli And Frmi Data Using The Kalman Filter, Jason Steffener
Dissertations
The advance of blood oxygen level dependent function magnetic resonance imaging, (BOLD fMRI), allows researchers to non-invasively investigate the functioning human brain. The BOLD fMRI response to brief stimuli is called the hemodynamic response function (HRF), which can vary across brain regions and across subjects.
Models of the HRF are used to increase sensitivity of statistical maps; however, they often don't account for spatial and temporal variance. Physiological effects, such as learning, fatigue or habituation, introduce mismatch between statistical models and the data. Methods that use minimal a priori information and track time varying signals are able to show the …
Relationship Between The Autonomic Nervous System And The Recovering Heart Post Exercise Using Heart Rate Variability, Pierre Asselin
Relationship Between The Autonomic Nervous System And The Recovering Heart Post Exercise Using Heart Rate Variability, Pierre Asselin
Theses
The goal of this thesis is to determine if a relationship exists between the activity of the autonomic nervous system (ANS) and the speed of heart rate recovery post maximal exercise. The parasympathetic branch of the ANS was assessed during rest by obtaining the high frequency (HF) component of the heart rate variability (HRV) frequency spectrum. The recovery time was estimated by fitting an exponential curve to the heart rate post exercise where the exponent was used to calculate the time constant to indicate recovery time. A regression was then performed on the HF and recovery time in order to …
Ambulatory Biopotential Measurement, Lakshmi Chitra Penugonda
Ambulatory Biopotential Measurement, Lakshmi Chitra Penugonda
Theses
Biopotential signals measure the electrical activity of different parts of the body. Conventional bedside monitors only provide information about the body under restricted conditions. Observation and documentation of biopotential signal during daily activities and the relation to patient symptoms may be important factors for clinical decision-making. Ambulatory monitoring helps to monitor the biopotential signal of a patient in the natural environment. The effective ambulatory system can help a physician to diagnose the patient's abnormality.
In this project, a low cost and flexible ambulatory biopotential system, compared to the commercially available systems, was designed and tested. Concurrently a software program was …
Analysis Of Acceleration And Deceleration During Cyclic Exercise, Jeena Vadi
Analysis Of Acceleration And Deceleration During Cyclic Exercise, Jeena Vadi
Theses
The Cyclic Exercise Protocol is a novel protocol that is designed to create a series of cyclic waves of exercise and recovery. This exercise protocol involves short bursts of exercise lasting for 60 seconds or less followed by a period of complete cardio recovery. This study involves the analysis of the acceleration and the deceleration regions of the cyclic exercise sessions. The objective of this study was to develop an algorithm to quantitatively analyze the acceleration and the deceleration regions of cyclic exercise sessions. The acceleration and the deceleration regions of cycles were split into three segments and each segment …
Non-Linear Digital Control Of A Mckibben Muscle System, Surinkumar Patel
Non-Linear Digital Control Of A Mckibben Muscle System, Surinkumar Patel
Theses
McKibben muscles are pneumatic actuators that have potential application in the rehabilitation of persons with physical impairments. These actuators have been known to exhibit similarities in human musculoskeletal systems. In order to better understand and improve the closed - loop control of these pneumatic muscles, a physical joint model was constructed with an agonist and an antagonist muscle operating under non-linear control. With the use of LabVIEW software, compliant McKibben air muscles and Flock-of-Birds sensor, the author was able to implement and compare a standard bang-bang controller and experimental non-linear digital Proportional (P) controller. The feedback mechanism is based on …
Applications Of Using The Odor Footprint Tool, Richard R. Stowell, L. Koppolu, Dennis D. Schulte, Richard K. Koelsch
Applications Of Using The Odor Footprint Tool, Richard R. Stowell, L. Koppolu, Dennis D. Schulte, Richard K. Koelsch
Department of Biological Systems Engineering: Conference Presentations and White Papers
The Odor Footprint Tool is a science-based computer resource for use in evaluating the potential odor impact of new and expanded animal production facilities. It was developed to assist livestock producers, their service providers, and county planning and zoning officials in making reasonable decisions while limiting the negative impact of livestock operations on surrounding neighbors and rural communities. The Odor Footprint Tool utilizes an EPA regulatory model (AERMOD), weather databases, new source code, and user input to generate regional odor roses, odor footprints, and directional setback distance curves. Odor roses provide a generic picture of the directionality of …
Using Ems’S To Improve Compliance On Livestock And Poultry Operations, L. Mark Risse, Richard K. Koelsch, Bill Bland, Elizabeth A. Bird, Thomas M. Bass
Using Ems’S To Improve Compliance On Livestock And Poultry Operations, L. Mark Risse, Richard K. Koelsch, Bill Bland, Elizabeth A. Bird, Thomas M. Bass
Department of Biological Systems Engineering: Conference Presentations and White Papers
Across the United States and abroad, innovative producers, processors, trade organizations and others in the agricultural sector are exploring the promise of Environmental Management Systems (EMS) to improve their environmental and business performance. An Environmental Management System or EMS helps farmers develop their own, personal strategies for reducing environmental risk on their operations by integrating environmental management considerations into production management decisions. It is a voluntary, flexible approach and is based on a producer's own sense of how best to manage an operation.
Partnerships for Livestock Environmental Management Systems is a 4-year project to explore the potential of livestock Environmental …
Cellulose Utilization By Clostridium Thermocellum: Bioenergetics And Hydrolysis Product Assimilation, Yi-Heng P. Zhang, Lee R. Lynd
Cellulose Utilization By Clostridium Thermocellum: Bioenergetics And Hydrolysis Product Assimilation, Yi-Heng P. Zhang, Lee R. Lynd
Dartmouth Scholarship
The bioenergetics of cellulose utilization by Clostridium thermocellum was investigated. Cell yield and maintenance parameters, Y(X/ATP)True = 16.44 g cell/mol ATP and m = 3.27 mmol ATP/g cell per hour, were obtained from cellobiose-grown chemostats, and it was shown that one ATP is required per glucan transported. Experimentally determined values for G(ATP)P-T (ATP from phosphorolytic beta-glucan cleavage minus ATP for substrate transport, mol ATP/mol hexose) from chemostats fed beta-glucans with degree of polymerization (DP) 2-6 agreed well with the predicted value of (n-2)/n [corrected] (n = mean cellodextrin DP assimilated). A mean G(ATP)(P-T) value of 0.52 +/- 0.06 was calculated …
Prevention Of Atrophic Nonunion Development By Recombinant Human Bone Morphogenetic Protein-7, Takeshi Makino, David J. Hak, Scott Hazelwood, Shane Curtiss, A. Hari Reddi
Prevention Of Atrophic Nonunion Development By Recombinant Human Bone Morphogenetic Protein-7, Takeshi Makino, David J. Hak, Scott Hazelwood, Shane Curtiss, A. Hari Reddi
Biomedical Engineering
Severe periosteal and soft tissue disruption at the time of fracture may result in the formation of an atrophic nonunion. We have developed a reproducible atrophic nonunion in an animal model. The purpose of this study was to evaluate whether the immediate application of recombinant human BMP-7 to the fracture site could rescue the healing process in this nonunion model. A total of 56 three month old Fisher 344 rats were utilized. A 1.25mm diameter K-wire was inserted into the femur in a retrograde fashion, and a mid-diaphyseal closed transverse fracture was created using a standard three point bending device. …
Simulations Of Transient Membrane Behavior In Cells Subjected To A High-Intensity Ultrashort Electric Pulse, Q. Hu, S. Viswanadham, R. P. Joshi, Karl H. Schoenbach, Stephen J. Beebe, P. F. Blackmore
Simulations Of Transient Membrane Behavior In Cells Subjected To A High-Intensity Ultrashort Electric Pulse, Q. Hu, S. Viswanadham, R. P. Joshi, Karl H. Schoenbach, Stephen J. Beebe, P. F. Blackmore
Bioelectrics Publications
A molecular dynamics (MD) scheme is combined with a distributed circuit model for a self-consistent analysis of the transient membrane response for cells subjected to an ultrashort (nanosecond) high-intensity (approximately 0.01-V/nm spatially averaged field) voltage pulse. The dynamical, stochastic, many-body aspects are treated at the molecular level by resorting to a course-grained representation of the membrane lipid molecules. Coupling the Smoluchowski equation to the distributed electrical model for current flow provides the time-dependent transmembrane fields for the MD simulations. A good match between the simulation results and available experimental data is obtained. Predictions include pore formation times of about 5-6 …
Gene Delivery Through Cell Culture Substrate Adsorbed Dna Complexes, Zain Bengali, Angela K. Pannier, Tatiana Segura, Brian C. Anderson, Jae-Hyung Jang, Thomas D. Mustoe, Lonnie D Shea
Gene Delivery Through Cell Culture Substrate Adsorbed Dna Complexes, Zain Bengali, Angela K. Pannier, Tatiana Segura, Brian C. Anderson, Jae-Hyung Jang, Thomas D. Mustoe, Lonnie D Shea
Biological Systems Engineering: Papers and Publications
Efficient gene delivery is a fundamental goal of biotechnology and has numerous applications in both basic and applied science. Substrate-mediated delivery and reverse transfection enhance gene transfer by increasing the concentration of DNA in the cellular microenvironment through immobilizing a plasmid to a cell culture substrate prior to cell seeding. In this report, we examine gene delivery of plasmids that were complexed with cationic polymers (polyplexes) or lipids (lipoplexes) and subsequently immobilized to cell culture or biomaterial substrates by adsorption. Polyplexes and lipoplexes were adsorbed to either tissue culture polystyrene or serum-adsorbed tissue culture polystyrene. The quantity of DNA immobilized …
Alterations In Wall Shear Stress Predict Sites Of Neointimal Hyperplasia After Stent Implantation In Rabbit Iliac Arteries, John F. Ladisa, Lars E. Olson, Robert C. Molthen, Douglas Anthony Hettrick, Phillip F. Pratt, Michael D. Hardel, Judy R. Kersten, David C. Warltier, Paul S. Pagel
Alterations In Wall Shear Stress Predict Sites Of Neointimal Hyperplasia After Stent Implantation In Rabbit Iliac Arteries, John F. Ladisa, Lars E. Olson, Robert C. Molthen, Douglas Anthony Hettrick, Phillip F. Pratt, Michael D. Hardel, Judy R. Kersten, David C. Warltier, Paul S. Pagel
Biomedical Engineering Faculty Research and Publications
Restenosis resulting from neointimal hyperplasia (NH) limits the effectiveness of intravascular stents. Rates of restenosis vary with stent geometry, but whether stents affect spatial and temporal distributions of wall shear stress (WSS) in vivo is unknown. We tested the hypothesis that alterations in spatial WSS after stent implantation predict sites of NH in rabbit iliac arteries. Antegrade iliac artery stent implantation was performed under angiography, and blood flow was measured before casting 14 or 21 days after implantation. Iliac artery blood flow domains were obtained from three-dimensional microfocal X-ray computed tomography imaging and reconstruction of the arterial casts. Indexes of …
Department Of Biological Systems Engineering Newsletter, Issue 1, April 2005
Department Of Biological Systems Engineering Newsletter, Issue 1, April 2005
BSE Department Magazine
Contents:
Welcome Comments from Department Head
New Lab in BSE
Dr. Martin Serves as BSE Interim Head
Splinter Labs
New Department Head
Hello-Goodbye
Faculty and Staff News
Cliff Hunter Memorial Picnic
Student News
Quarter-Scale Tractor Team
Freshmen Eat Cars
Scholarship Recognition
Annual Spring Recognition Banquet
New Graduates
Generous Gifts to Endowments in BSE
Identification And Expansion Of Pancreatic Stem/Progenitor Cells., You-Qing Zhang, Marcie Kritzik, Nora Sarvetnick
Identification And Expansion Of Pancreatic Stem/Progenitor Cells., You-Qing Zhang, Marcie Kritzik, Nora Sarvetnick
Journal Articles: Regenerative Medicine
Pancreatic islet transplantation represents an attractive approach for the treatment of diabetes. However, the limited availability of donor islets has largely hampered this approach. In this respect, the use of alternative sources of islets such as the ex vivo expansion and differentiation of functional endocrine cells for treating diabetes has become the major focus of diabetes research. Adult pancreatic stem cells /progenitor cells have yet to be recognized because limited markers exist for their identification. While the pancreas has the capacity to regenerate under certain circumstances, questions where adult pancreatic stem/progenitor cells are localized, how they are regulated, and even …
Blood Flow Measurements With Magnetic Resonance Phase Velocity Mapping, George P. Chatzimavroudis
Blood Flow Measurements With Magnetic Resonance Phase Velocity Mapping, George P. Chatzimavroudis
Chemical & Biomedical Engineering Faculty Publications
Magnetic resonance (MR) phase velocity mapping (PVM) is a non-invasive technique that can measure the flow velocity in any spatial direction in an imaging slice. This technique has wide application in the clinical field in quantifying blood flow, as well as in non-biomedical areas. This review describes the value and/or potential of MR PVM as a diagnostic/monitoring technique in heart valve regurgitation and in the total cavo-pulmonary connection. A single slice placed in the aortic root can accurately quantify the aortic regurgitant volume. A multi-slice control volume method has high potential for the quantification of the mitral regurgitant volume. …
Segmentation Of Non-Viable Myocardium In Delayed Enhancement Magnetic Resonance Images, Arunark Kolipaka, George P. Chatzimavroudis, Richard D. White, Thomas P. O’Donnell, Randolph M. Setser
Segmentation Of Non-Viable Myocardium In Delayed Enhancement Magnetic Resonance Images, Arunark Kolipaka, George P. Chatzimavroudis, Richard D. White, Thomas P. O’Donnell, Randolph M. Setser
Chemical & Biomedical Engineering Faculty Publications
Purpose: To evaluate six algorithms for segmenting non-viable left ventricular (LV) myocardium in delayed enhancement (DE) magnetic resonance imaging (MRI). Methods: Twenty-three patients with known chronic ischemic heart disease underwent DE-MRI. DE images were first manually thresholded using an interactive region-filling tool to isolate non-viable myocardium. Then, six thresholding algorithms, based on the image intensity characteristics of either LV blood pool (BP), viable LV myocardium, or both, were applied to each image. For the Mean−2SDBP algorithm, thresholds were equal to the mean BP intensity minus twice its standard deviation. For the Mean+2SDSemi, Mean+3SDSemi, Mean+2SDAuto …
Numerical Simulation Of Nanopulse Penetration Of Biological Matter Using The Z -Transform, Shengjun Su
Numerical Simulation Of Nanopulse Penetration Of Biological Matter Using The Z -Transform, Shengjun Su
Doctoral Dissertations
Short duration, fast rise time ultra-wide-band (UWB) electromagnetic pulses (“nanopulses”) are generated by numerous electronic devices in use today. Moreover, many novel technologies involving nanopulses are under development and expected to become widely used soon. Study of nanopulse bioeffects is needed to probe their useful range in possible biomedical and biotechnological applications, and to ensure human safety.
Based on the well-known dispersive properties of biological matter and their expression as a summation of terms corresponding to the main polarization mechanisms, the Cole-Cole expression is commonly employed to describe the frequency dependence of the dielectric properties of a tissue. Solving the …
Application Of Self -Assembled Ultrathin Film Coatings To Stabilize Enzyme Encapsulation And Activity In Alginate Microspheres, Rohit Srivastava
Application Of Self -Assembled Ultrathin Film Coatings To Stabilize Enzyme Encapsulation And Activity In Alginate Microspheres, Rohit Srivastava
Doctoral Dissertations
Alginate-based hydrogels have been used for the encapsulation of a variety of materials, including enzymes, proteins, and cells for a wide range of applications from drug delivery to biosensors and bioreactors. However, due to the high porosity of the matrix, it has been increasingly difficult to retain macromolecules inside the alginate matrix, leading to loss in functionality over time. In an effort to improve the stability for long-term biosensor use, this work investigated layer-by-layer self-assembly as a potential technique to provide a diffusion barrier to an encapsulated macromolecule. Alginate microspheres (∼2–50μm radius) were fabricated using an emulsification technique, and were …