Engineering Commons^™

Electromagnetic Theory And Applications, Nicholas Madamopoulos, George Kliros

Open Educational Resources

This book intends to provide both the fundamentals of Electromagnetics but also some practical applications of the concepts covered. Having taught electromagnetics for several years, the authors feel that many times the field of electromagnetics comes as “old” and often times students do not appreciate the concepts and their importance in everyday applications. The authors intend to accompany the EM concepts with life applications. Hence, students may see the direct impact of the knowledge they acquire through the study of the field of electromagnetics and better appreciate the field.

Coupling Atr-Ftir Spectroscopy With Multivariate Analysis For Polymers Manufacturing And Control Of Polymers’ Molecular Weight, Tung Nguyen, Ahmad Arabi Shamsabadi, Mona Bavarian

Department of Chemical and Biomolecular Engineering: Faculty Publications

Acrylate-based polymers are commonly used in the chemical industry. Consistent manufacturing of these polymers with the help of Process Analytical Technology (PAT) is very desirable. The capability of monitoring polymers’ molecular weight in real-time reduces operation time and eliminates the frequent samplings needed for quality control. Herein, molecular weight (M_w) of glycidyl methacrylate-co-methyl methacrylate (GMA-co- MMA) copolymer was monitored in real-time using mid-infrared ATR-FTIR spectroscopy. The Principal Component Analysis (PCA) and Partial Least Square (PLS) models were then utilized to examine, improve the latent space, and select high-quality spectra. We show that acquiring highly correlated spectra enhances the …

Developing A Finite Element Model For Evaluating The Posterior Tibial Slope In A Medial Opening Wedge High Tibial Osteotomy, Victor Alexander Carranza

Electronic Thesis and Dissertation Repository

This thesis aimed to develop and validate a computation finite element (FE) model to investigate the effect of hinge axis orientation on the posterior tibial slope (PTS) and mechanical medial proximal tibial angle (mMPTA) while analyzing the mechanical response around the hinge in a medial opening wedge high tibial osteotomy (MOWHTO). Chapter 2 highlights the importance of selecting an appropriate modeling method that best represents the clinical scenario. Chapter 3 validated a FE model using the Bland-Altman agreement analysis which yielded 95% limits of agreement of −0.9° to 1.2° for PTS and −1.4° to 1.9° for mMPTA. A parametric study …

Polyethyleneimine Shell Nucleic Acid Nanostructures From Gold Nanoparticle Template For Chemotherapeutic Drug Delivery, Brendan Guy Rucci

Theses and Dissertations

The next generation of anticancer agents will emerge from rationally designed nanostructured materials. This work involved the synthesis and characterization of novel hollow DNA-conjugated gold nanoparticles (DNA-AuNPs) for controlled drug delivery. Polyethyleneimine (PEI) was bound to citrate-capped AuNPs, forming polymer-shell nanoparticles. Dissolution of the gold core via iodine formed hollow core polymeric nanoparticles (HCPPs) and a high density of DNA (85 molecules/particle) containing daunorubicin was conjugated. Particles were spherical with an average diameter of 105.7±17.3 nm and zeta potential of 20.4±3.54 mV. We hypothesize the DNA backbone electrostatically condensed to the primary amines on the surface of the particle toroidally, …

Investigation Of Dynamic Culture On Matrix-Derived Microcarriers As A Strategy To Modulate The Pro-Regenerative Phenotype Of Human Adipose-Derived Stromal Cells, Mckenna R. Tosh

Electronic Thesis and Dissertation Repository

Pre-conditioning of adipose-derived stromal cells (ASCs) by tuning the cellular microenvironment during expansion has the potential to modulate their pro-regenerative functionality. The current study investigated the effects of microcarrier composition (decellularized adipose tissue versus collagen), oxygen tension (2% versus ~20% O₂) and stirring rate (static, 20, 40 rpm) on human ASCs cultured within spinner flask bioreactors. Dynamic culturing under 20% O₂ resulted in more consistent cell growth on both microcarrier substrates, leading to increases in microcarrier contraction and stiffness. Culturing on the microcarriers modulated the hASC immunophenotype, with varying CD90 and CD26 expression levels observed under the …

Coupling Nitrate Capture With Ammonia Production Through Bifunctional Redox-Electrodes, Kwiyong Kim, Alexandra Zagalskaya, Jing Lian Ng, Jaeyoung Hong, Vitaly Alexandrov, Tuan Anh Pham, Xiao Su

Department of Chemical and Biomolecular Engineering: Faculty Publications

Nitrate is a ubiquitous aqueous pollutant from agricultural and industrial activities. At the same time, conversion of nitrate to ammonia provides an attractive solution for the coupled environmental and energy challenge underlying the nitrogen cycle, by valorizing a pollutant to a carbon-free energy carrier and essential chemical feedstock. Mass transport limitations are a key obstacle to the efficient conversion of nitrate to ammonia from water streams, due to the dilute concentration of nitrate. Here, we develop bifunctional electrodes that couple a nitrate-selective redox-electrosorbent (polyaniline) with an electrocatalyst (cobalt oxide) for nitrate to ammonium conversion. We demonstrate the synergistic reactive separation …

A 3d Bioprinted Hydrogel Microfluidic Device For Screening Applications, Anant Bhusal

Theses and Dissertations

The microfluidic enabled the integration of engineered miniaturized tissue models for drug screening. Conventional polydimethylsiloxane or plastic-based devices require multiple fabrication steps, which are challenging. We developed a 3D bioprinting approach to create prototypes of hydrogel-based multi-material microfluidic devices integrated with microtissue models. The approach utilizes poly(ethylene glycol) diacrylate and gelatin-methacryloyl to create microfluidic chips using multi-material bioprinting capacity with a high resolution of 15µm on x-y and 50µm on the z-axis and post-printing viability of >90%. We demonstrated easy regulation of stiffness from 24±5 kPa to 1,180±9 kPa and burst pressure from 16±1kPa to 256±19 kPa in the chip …

Effect Of Blank Moisture Content On Forming Behaviour And Mechanical Properties Of Paperboard Tray Packages, Arvo Niini, Lena Berthold, Tobias Müller, Panu Tanninen, Jens-Peter Majschak, Juha Varis, Ville Leminen

Journal of Applied Packaging Research

Tray blanks were moisturised to study the effect of different blank moisture content levels on forming behaviour and mechanical properties of paperboard tray packages. The blank moisturisation was done by spraying water to the blanks before their three-dimensional (3D) forming. The trays were 3D formed by press forming or deep drawing. Visual quality and punch force values were used as indicators to evaluate the forming behaviour of the trays. The mechanical properties of the trays were investigated with compression, torsion, and storing tests. A high blank moisture content reduced the punch force, and the elevated blank moisture was connected to …

Wearable Sensing System For Noninvasive Monitoring Of Intracranial Biofluid Shifts In Aerospace Applications., Jacob L Griffith, Kim Cluff, Grant M Downes, Brandon Eckerman, Subash Bhandari, Benjamin E Loflin, Ryan Becker, Fayez Alruwaili, Noor Mohammed

Henry M. Rowan College of Engineering Departmental Research

The alteration of the hydrostatic pressure gradient in the human body has been associated with changes in human physiology, including abnormal blood flow, syncope, and visual impairment. The focus of this study was to evaluate changes in the resonant frequency of a wearable electromagnetic resonant skin patch sensor during simulated physiological changes observed in aerospace applications. Simulated microgravity was induced in eight healthy human participants (n = 8), and the implementation of lower body negative pressure (LBNP) countermeasures was induced in four healthy human participants (n = 4). The average shift in resonant frequency was -13.76 ± 6.49 MHz for …

Comparison Of In-Vitro 3d Human Embryoids With Current Models For Gastrulation, Jin Park

McKelvey School of Engineering Theses & Dissertations

Gastrulation is an early morphogenetic process that is conserved across most metazoans and lays out the future body plan through the formation and shaping of the three germ layers: endoderm, mesoderm, and ectoderm. Despite its importance, not much is known about the events surrounding human gastrulation that occurs in utero due to ethical and technical limitations on studying human embryos. Therefore, many researchers have devised protocols for creating in vitro models of gastrulation using embryonic stem cells. Initially starting with mouse embryonic stem cells, the field of in vitro embryo models has advanced rapidly, with protocols using human embryonic stem …

Relationships Among Shoulder Rotational Strength, Range Of Motion, Pitching Kinetics, And Pitch Velocity In Collegiate Baseball Pitchers, Janelle A. Cross, Austin William Higgins, Cody C. Dziuk, Gerald F. Harris, William G. Raasch

Biomedical Engineering Faculty Research and Publications

Relationships among shoulder rotational strength, range of motion, pitching kinetics, and pitch velocity in collegiate baseball pitchers. J Strength Cond Res 37(1): 129–135, 2023—Throwing shoulder injuries are the most common type of injury experienced by baseball pitchers. Weakness in the shoulder musculature and insufficient throwing arm range of motion are both risk factors for developing a shoulder injury. The goal of this study was to determine correlations among shoulder rotational strength, range of motion, pitching kinetics, and pitch velocity in collegiate pitchers. Thirteen uninjured male college pitchers were evaluated. Clinical measures included shoulder internal and external rotation range of motion, …

Marineepi: A Gui-Based Matlab Toolbox To Simulate Marine Pathogen Transmission, Gorka Bidegain, Tal Ben-Horin, Eric N. Powell, John M. Klinck, Eileen E. Hofmann

CCPO Publications

The Graphical User Interface (GUI) MarineEpi is presented as a Matlab toolbox for easily (i) constructing disease transmission models for different marine host-pathogen systems, (ii) running simulations by specifying initial conditions and model parameters, and (iii) interpreting the resulting time series of the host and pathogen population dynamics. MarineEpi users can generate models for systems in which pathogen transmission occurs through contact with infected individuals (SI), contact with dead infected individuals (SID), contact with environmental pathogens released by infected individuals (SIP), and contact with environmental pathogens released by dead infected individuals (SIPD). MarineEpi is a freely available GUI that provides …

Estimation Of Free Water-Corrected Microscopic Fractional Anisotropy., Nico J J Arezza, Tales Santini, Mohammad Omer, Corey A Baron

Medical Biophysics Publications

Water diffusion anisotropy MRI is sensitive to microstructural changes in the brain that are hallmarks of various neurological conditions. However, conventional metrics like fractional anisotropy are confounded by neuron fiber orientation dispersion, and the relatively low resolution of diffusion-weighted MRI gives rise to significant free water partial volume effects in many brain regions that are adjacent to cerebrospinal fluid. Microscopic fractional anisotropy is a recent metric that can report water diffusion anisotropy independent of neuron fiber orientation dispersion but is still susceptible to free water contamination. In this paper, we present a free water elimination (FWE) technique to estimate microscopic …

Extraction, Quantification, Characterization, And Application In Food Packaging Of Chitin And Chitosan From Mushrooms: A Review, Bullyamini Alimi, Shivani Pathania, Jude Wilson, Brendan Duffy, Jesus Maria Frias

Articles

The application of chitin in food systems is limited by its insolubility in some common solvents and poor degradability. Hence, it is deacetylated to obtain chitosan, an industrially important derivative with excellent biological properties. Fungal-sourced chitosan is gaining prominence and industrial attraction because of its superior functional and biological properties, and vegan appeal. Further, the absence of such compounds as tropomyosin, myosin light chain, and arginine kinase, which are known to trigger allergic reactions, gives it an edge over marine-sourced chitosan in food and pharmaceutical applications. Mushrooms are macro-fungi with a significant content of chitin, with many authors reporting the …

A Label-Free Fiber Ring Laser Biosensor For Ultrahigh Sensitivity Detection Of Salmonella Typhimurium, Shi Qiu, Bin Liu, Yuankui Leng, Edward Fox, Xian Zhou, Binbin Yan, Xinzhu Sang, Long Long, Xingdao He, Jinhui Yuan, Gerald Farrell, Qiang Wu

Articles

The rapid detection of low concentrations of Salmonella Typhimurium (S. Typhimurium) is an essential preventive measure for food safety and prevention of foodborne illness. The study presented in this paper addresses this critical issue by proposing a single mode-tapered seven core-single mode (STSS) fiber ring laser (FRL) biosensor for S. Typhimurium detection. The experimental results show that the specific detection time of S. Typhimurium is less than 20 min and the wavelength shift can achieve -0.906 nm for an S. Typhimurium solution (10 cells/mL). Furthermore, at a lower concentration of 1 cell/mL applied to the biosensor, a result of -0.183 …

3-Dimensional Muscle Constructs: Using Hydrogels In Order To Model The Effects Of Exercise In Disease Conditions, Mark Mchargue

Theses and Dissertations--Biomedical Engineering

Currently, there is no standard in vitro model for studying the effects of mechanical stimulation on muscle in type II diabetes. Existing models primarily utilize electrical stimulation, which does not fully recapitulate the effects of exercise. In this thesis, we create a standardized in vitro model of murine muscle that can recapitulate the benefits seen in exercise when mechanically stimulated. Moreover, we show that a type II diabetes environment has similar effects on the muscle in vitro as well as in vivo.

Simulating The Effect Of Gut Microbiome On Cancer Cell Growth Using A Microfluidic Device, Ekansh Mittal, Grace Cupp, Youngbok (Abraham) Kang

Faculty Publications - Biomedical, Mechanical, and Civil Engineering

The imbalance in the gut microbiome plays a vital role in the progression of many diseases, including cancer, due to increased inflammation in the body. Since gut microbiome-induced inflammation can serve as a novel therapeutic strategy, there is an increasing need to identify novel approaches to investigate the effect of inflammation instigated by gut microbiome on cancer cells. However, there are limited biomimetic co-culture systems that allow testing of the causal relationship of the microbiome on cancer cells. Here we developed a microfluidic chip that can simulate the interaction of the gut microbiome and cancer cells to investigate the effects …

Expression Optimization Of The Gst-Gfp Fusion Protein Through The Alteration Of Induction Conditions, Matthew J. Vaccaro

Honors Undergraduate Theses

This research sought to determine which induction condition resulted in the greatest GST-GFP fusion protein expression. It will hopefully serve as a guide for future researchers trying to produce their own recombinant protein containing GST and GFP-tags. The CDNB Enzyme Assay was used to determine the quantity of GST-GFP fusion protein present and tested three variables: IPTG concentration, duration, and temperature of induction. The findings showed that IPTG concentration, temperature, and induction duration all had a significant impact on protein expression. Induction temperatures of 20 °C and 25 °C showed better protein expression at IPTG concentrations of 1.0 mM IPTG …

Evaluation Of The Impact Of The Covid-19 Pandemic On The Teaching Of Otolaryngology And Cervico-Facial Surgery, I. Tahiri, H. Bensouda, O. Haddani, O. El Houari, S. Anajar, L. Taali, A. Hajjij, M. Essaadi, M. Jahidi, F. Benariba, M. Zalagh, F. Guessous, S. Chaouir

Health Sciences

Background: During the Covid-19 pandemic, distance learning is increasingly present in the field of education, particularly in the health sciences. This type of teaching has emerged as the appropriate solution to the problem of knowledge transfer. The objective of this study is to evaluate the impact of distance learning of the ENT (ear, nose and throat) and CFS (cervico-facial surgery) module on students and the impact of the pandemic on their quality of life. Methods: We conducted a survey on students' feelings about distance learning courses, the impact of the pandemic on their lifestyle and the consequences of the protective …

Student Evaluation Of Pre-Clinical Teaching On A Dental Simulator, Manal Elhijazi, Hafsa Elmrini, Ihsane Benyahya

Health Sciences

Context: Student evaluation of teaching (SET) is a pedagogical tool which is part of a quality control process of teaching. Material and methods: An anonymous and voluntary e-questionnaire was sent to all 3rd year students of the Faculty of Dentistry in university Mohamed VI of sciences and health at the end of the academic year 2021-2022 in order to evaluate the progress of practical pre-clinical learning by dental simulator in conservative dentistry. The aim was to evaluate the teaching tools, the organization of the lessons, the content of the program as well as their overall perceptions of this practical pre-clinical …

To Publish Or Not To Publish Phd Parts Before Its Completion Is Also An Ethical Question, Christos Melidis

Health Sciences

No Abstract for this article type.

Artificial Intelligence In Dentistry : Knowledge And Perceptions Of Moroccan Students, Manal Elhijazi, Ihsane Benyahya

Health Sciences

Introduction: Artificial intelligence (AI) is a revolution in education, research and health. The aim of this study is to assess the views and perceptions of dental students regarding artificial intelligence and its impact on their future professional practice. Methods: A voluntary anonymous e-questionnaire was sent to all 4th and 5th year dental students of the Faculty of Dentistry after receiving a course on artificial intelligence. The questionnaire consisted of sections to assess students' knowledge of artificial intelligence and its possible applications in dentistry as well as ethical considerations. Statistical analysis of the data was carried out using SPSS version 23 …

Prepubertal Periodontitis In Children: For An Adequate Diagnosis And Optimal Care, F.Z. El Mouatarif, S. Chemlali, M. Hamza, J. Kissa, S. El Arabi

Health Sciences

Prepubertal periodontitis (PP) is a rare and rapid progressive condition found a young cohort of patients that results in destruction of the periodontal support of the primary dentition. Its generalized form, prepubertal periodontitis is often associated with a significant gingival tissue inflammation and fast bone loss with attachment loss leading to the tooth loss. The localized form of PP is characterized by a much more discreet inflammation and slow evolution. It can be associated with a known underlying systemic disease or may occur as part of a recognized syndrome or as an isolated finding. Different treatment modalities can be used …

Biological Parameters And The Histological Response In Rectal Cancer Treated By Neoadjuvant Chemoradiotherapy: A Moroccan Cohort, A. Naim, N. Bouanani, F. Safini, S. Mounaime, Soumaya Rafii, L. Lachker, F. Guessous, M. Khaliss, N. Tawfiq, A. Badou

Health Sciences

Introduction: Multimodal management of rectal cancer, combining neoadjuvant Radio chemotherapy followed by total Mesorectal therapy (TME), has been shown to improve locoregional control. However, the histological response is variable independently of the initial tumor stage. Some recent data suggest the usefulness of the lymphocyte-monocyte ratio (LMR), neutrophil-lymphocyte ratio (NLR), and platelet-lymphocyte ratio (PLR) in predicting the histological response to neoadjuvant therapy. This study aimed to investigate the correlation between the complete histological response (pCR) after neoadjuvant radio chemotherapy and biological parameters (LMR, NLR and PLR) in rectal cancer patients.

PATIENTS AND METHODS: This retrospective study was conducted in three Moroccan …

An Experimentally Validated Computational Model For The Degradation And Fracture Of Magnesium-Based Implants In A Chemically Corrosive Environment, Mark M. Ousdigian

Dissertations, Master's Theses and Master's Reports

In the orthopedic and cardiovascular fields there is a growing interest for biodegradable implants, which can be naturally degraded in the body environment over time so that no extraction surgery is required. These implants must be designed to maintain their strength until the fracture has healed in the body, which could be influenced by many factors such as -the patient’s age, activities, body weight, pre-existing conditions etc. Hence, an ideal implant design should be done on a patient-by-patient basis. In the present work, a computational model is developed to predict the degradation and fracture of magnesium-based implants in a stress-coupled …

An Experimental Study On The Mechanical Properties And Chemical Composition Of Lcd 3d Printed Specimens, Sebastian Gomez

Electronic Theses and Dissertations

Additive manufacturing technologies have been enhanced throughout the years yet have surprised the manufacturing industry due to their high-end surface finish and dimensional accuracy. Different experiments have been done to identify a specific phenomenon known in the vat-polymerization field. Distortion and dimensional inaccuracy tend to affect the overall properties of the process, either physical or chemical. This approach allows the understanding of how the physical properties have been affected and how to study the chemical properties to avoid this type of phenomenon. The chemical reaction between polymer and UV light has been studied and experimented with to the point that …

Synthesis And Processing Of Pcl And Irdye Nanoparticles For Application In Drug Release Mechanism, Michael Adeniyi

Electronic Theses and Dissertations

The objective of this study is to produce core-shell nanoparticles utilizing PCL and IRDye and investigate the nanoparticle release mechanism. Biodegradable polymer, Polycaprolactone (PCL), was electrosprayed separately with two types of IRDye, NHS and Dextran Texas red. The solution of PCL was formed by mixing PCL in a solution of 9.47ml Acetic Acid, 9.47ml Formic Acid, and 1.05ml Trifluoroethanol, following a ratio of 9:9:1. The two solutions of IRDye were prepared by mixing 2mg of the IRdye with 20ml of DMF at a rate of 0.1mg/ml.

The NHS IRDye was electrosprayed coaxially with PCL and the Dextran Texas red dye …

Chronic Anemia Revealing An Idiopathic Watermelon Stomach: Case Report, Hanane Delsa, Imane Rahmouni, Yassamin Benhayoun Sadafyine, Fatima Belabbes, Anass Nadi, Fedoua Rouibaa

Health Sciences

Watermelon stomach, also known as gastric antral vascular ectasia (GAVE) syndrome, is a rare entity. Patients often present with profound unexplained anemia with or without bleeding externalization. We made the diagnosis during a digestive endoscopy for an etiological assessment of this anemia. Endoscopically, antral erythematous lesions in stripes with a punctate appearance, sometimes hemorrhagic, may suggest a watermelon stomach. The pathophysiology of the watermelon stomach remains complex and unclear. Although several pathologies remain implicated, sometimes, it can be idiopathic. The effectiveness of numerous treatments has been evaluated with relatively satisfactory results. This is a rare case of an idiopathic watermelon …

The Strength Of Motivation For Dental Students, Manal Elhijazi, Ihsane Benyahya

Health Sciences

Context: Motivation plays a key role in academic success. It is a dynamic process that maintains perseverance and tenacity in the face of difficulty. The purpose of our study was to measure and compare the strength of dental students' motivation at the beginning and the end of their training Material and methods: an anonymous self-administered voluntary questionnaire was distributed to 1st and 6th year students at the Faculty of Dentistry in Casablanca This questionnaire consisted of 30 closed questions divided into 3 sections, the first of which provided information on socio-demographic data, the second is devoted to measuring the strength …

Verification Of Proton Range Predictions In Proton Treatment Planning Using X-Ray Ct Or Proton Ct Imaging, Nicholas S. Yee

Graduate Research Theses & Dissertations

The objective of this paper is to compare the range errors for two treatment plans; one using x-ray CT and the other using proton CT for calculating dose distributions in an animal tissue phantom. We shot 150 MeV proton beam through a meat phantom to a film stack to measure the exponential drop of dose at the Bragg peak until zero dose remained. Plotting the depth dose curves and performing gamma analyses are two ways to quantify the proton range errors when comparing them to depth dose curves from film measurements in the phantom. The depth dose curves give us …