Digital Commons Network^™

Nasoalveolar Molding ; A Rise In Early Management Of Newborn Patient With Cleft Lip And Palate, Reeya Agrawal, Dr Pallavi Daigavane, Dr Amit Reche

International Arab Journal of Dentistry

Orofacial clefts are one of the most frequent congenital oral and maxillofacial abnormalities. When these babies are roughly three months old, lip rebuilding , also known as cheiloplasty, is a critical concern. In several cleft facilities ,To improve the treatment success, Presurgical Nasoalveolar Molding (NAM) has been included in the therapy protocol. In patients with cleft lip and palate, this technique is routinely used to bring the alveolar segments in to normal alignment and improve nasal symmetry.The advantages of utilising this approach as part of a treatment plan for newborns born with cleft lip and palate will be discussed in …

Synopsis On The Role Of Diode Laser In Root Canal Disinfection, Ashraf M. Abu-Seida, Mohamed M.N. El-Tayeb, Elhassan E. Hassanein

International Arab Journal of Dentistry

Effective root canal disinfection is necessary for success of endodontic treatment. Traditional chemo-mechanical techniques such as sodium hypochlorite, mechanical preparation and calcium hydroxide used for intracanal disinfection usually fail in cases of biofilm-related infections. Therefore, several new strategies are applied for root canal disinfection. One of these strategies is using of diode laser that has recently gained significant attention in the endodontic practice due to its antibacterial action, bio-stimulation, decrease of pain and improvement of success. Moreover, it has several advantages like its low cost, easily application, penetration power into dentine and smaller size device compared with other types of …

Accuracy And Trueness Of Exporting Computer Aided Designs Of 3-Unit Fixed Dental Prosthesis By 3 Cad Systems, Ezzat Abou-Alnaga, Ashraf Hussein, Ahmed Naguib, Shereen Ahmed Nossair

Future Dental Journal

Objectives: Computer-aided design (CAD) software programs offer the option to export 3D scans and designs across different CADCAM systems, commonly referred to as open CADCAM technology. However, there is insufficient evidence of whether this exporting procedure has an impact on the accuracy of digital designs.This study aimed to investigate the accuracy of exporting of computer aided designs (CAD) of three-unit fixed dental prosthesis using 3 CAD systems. Materials and Methods: Three CAD softwares (inLab 17™, CeraMill Mind™, Dental System 2017™) were used to generate designs of a three-unit fixed partial denture. The designs generated by each CAD software were exported …

Assessment Of The Effect Of Two Different Digital Fabrication Techniques On Marginal And Internal Fit Of Interim Fixed Dental Prothesis, Mohamed A. Shalaby, Mennatallah M. Wahba, Hisham I. Al-Ansari, Ahmed N. Mohamed

Future Dental Journal

Aim: The aim of that study was to evaluate the marginal and internal fit of a 3-unit, and 6-unit interim fixed dental prosthesis manufactured through milling and 3D printing technologies. Materials and Methods: Forty-eight interim fixed dental prostheses (FDP) were equally divided into two groups according to the fabrication technique. In group (MT), specimens were fabricated through milling technology while in group (PT), specimens were obtained by 3D printing. Each group was subdivided equally according to the FDP span length into 3-unit FDP (SFDP), and 6-unit FDP (LFDP). Marginal and internal fit were measured through the superimposition of the digital …

Digital Fabrication Of Attachment For Implant-Anchored Auricular Prosthesis (Case Report)., Hussein El Charkawi Proffesor

Future Dental Journal

Aim: This novel technique, has adopted digital technology to fabricate a customized precision attachment for a patient who has lost his attachment which anchor his implant retained auricular prosthesis. A scanner was used to acquire the ball abutment’ geometry of craniofacial implant in the mastoid area. CAD/CAM technology and special software was used to fabricate a customized small PEEK precision attachment that was no longer available in the market. This attachment was picked-up by an auricular prosthesis. The retention qualities of the auricular prosthesis with this attachment was satisfactory for both the patient and the dentist. This novel approach will …

Prevalence Of Molar Incisor Hypomineralization In A Group Of Egyptian Children, Ayah Essam Almenawi B.D.S, Norhan Abd El-Wahab El-Dokky Professor Of Pediatric Dentistry & Dental Public Health, Soad Abdelmoniem Abdelmoniem Professor Of Pediatric And Dental Public Health

Future Dental Journal

Background: Molar incisor Hypomineralization (MIH) has become a more widespread problem around the world, while its prevalence in Egypt is underestimated with no data on its correlation to Hypomineralization of Second Primary Molars (HSPM). Aim: Estimate the prevalence of MIH and HSPM in Egypt, investigate the possibility of HSPM being a predictive factor for MIH, and the probable etiological factors for MIH. Material and Methods: Three hundred and seventeen healthy children aged seven to ten years old were dentally examined for Molar Incisor Hypomineralization and Hypomineralization of Second Primary Molars and all potentially correlated etiological factors. Both MIH and HSPM …

Evaluation Of Accuracy Of Intraoral Scanners Versus Extra Oral Scanners In Different Dental Arch Measurements, Mohamed Walid Saleh, 20143278@Fue.Edu.Eg , Future University In Egypt, Fouad Sharaby Fsharaby@Dentistry.Cu.Edu.Eg , Associate Professor Of Orthodontic Department Of Orthodontics Faculty Of Dentistry Cairo University, Essam Nassef Essam.Nasssef@Fue.Edu.Eg , Professor Of Orthodontic Department Of Orthodontics Faculty Of Oral And Dental Medicine Future University In Egypt

Future Dental Journal

Background: Orthodontics has been influenced by new technologies in many areas. There is a shift toward digitization of patient’s information and data. Aim: The aim of this study was to compare the accuracy of intraoral scanner and extra oral scanners using different dental arch measurements. Materials and Methods: The sample size consisted of 44 dental stone models for patients who finished orthodontic treatment. For each subject two digital models were made, one digital model obtained from extra oral scanner and one digital model obtained from Intra oral scanner. An external examiner measured intermolar width, intercanine width, mesiodistal width of the …

Changes In Lip Length And Strain After En-Masse Retraction With Maximum Anchorage In Female Patients With Bimaxillary Protrusion, Leena Shibl, Amr El-Beialy, Yehya Mostafa, Heba Dehis

Future Dental Journal

Aim: The aim of the study is to evaluate the effect of en-masse retraction with maximum anchorage on the lip length, lip strain, and interlabial gap in adult female patients with bimaxillary protrusion. Materials and Methods: Thirteen patients underwent initial records including photographs, study casts, and cephalometric x-rays. En-masse retraction was performed using friction mechanics, with the use of temporary anchorage devices and power chains after the extraction of first premolars. The soft tissue was analyzed using lateral cephalometric radiographs before and after retraction. Results: The results showed that en-masse retraction had a significant effect on reducing lip strain, increasing …

Questionnaire Survey On Pain & Mini-Implant Failure In Class Ii Female Patients After Extraction Of Maxillary Second Molars Using Infra Zygomatic Mini Implants, Hosam Abdullah Zaza, Nagwa El Mangoury, Amr El Dakrory, Mostafa El Dawlatly

Future Dental Journal

Background: Skeletal anchorage devices have been developed for case requiring absolute anchorage during orthodontic treatment. One of these anchorage devices is the Infra-zygomatic mini-implant type. However, the pain associated with this type of appliance have not been sufficiently evaluated from the patient’s point of view. Aim: The aim of this study was to survey patients for one week after insertion of the infra-zygomatic mini-implants and 1 week following every reactivation in order to evaluate their pain and discomfort as well as the percentage of mini-screw failure. Materials and methods: 10 patients requiring infra-zygomatic mini-implants were selected. All participants completed questionnaires …

Expression Of Vimentin, Α-Sma And Tgf-Β In Different Grades Of Oral Squamous Cell Carcinoma, Hala El-Kammar, Waleed F. Esmael, Nermeen S. Afifi

Future Dental Journal

Abstract

Background: Oral Squamous cell carcinoma (OSCC) is typically discovered at an early stage; nevertheless, regional lymph node metastases are prevalent; therefore, surgical excision of the primary tumor is commonly coupled with neck dissection and radiotherapy. Cancer cells become invasive by acquiring a mesenchymal phenotype, a process known as the epithelial-to-mesenchymal transition. Vimentin, α-SMA and TGF-β expressions are believed to take part in EMT and tumor progression. Aim: this work aimed to evaluate the expression of Vimentin, α-SMA and TGF-β on OSCC progression and hence propose potential role as potential prognostic markers or therapeutic targets. Materials and methods: twenty-four specimens …

Assessment Of Crestal Bone Loss And Implant Stability Of Implant Drilling Protocol At Low Speed Without Irrigation Versus Conventional Drilling Protocol, Omar Elmeligy O. Elmeligy, Ahmed Farid Shehab, Sameh Mekhemer, Ahmed Abozekry

Future Dental Journal

Abstract

Aim: This study assesses crestal bone loss surrounding dental implants, primary and secondary stability in sites prepared by conventional versus low speed drilling protocol. Material and Methods: Ten patients received 20 implants to restore an edentulous area in the lower posterior mandibular area. Patients were blindly divided into a control and study group. In the control group, sequential drilling was performed at 1,200 rpm and torque of 30 Ncm with irrigation till reaching the planned length and diameter. In the Study group, sequential drilling was performed at 150 rpm and torque of 50 Ncm without irrigation till reaching …

Computer Guided Versus Conventional Maxillary Sinus Augmentation Using Allogenic Bone Blocks With Simultaneous Implant Placement In Severely Pneumatized Sinuses, Hisham G. Zulhemma Department Of Oral And Maxillofacial Surgery, Future University In Egypt, Egypt. 20172740@Fue.Edu.Eg, Waleed Ragab El-Beialy Professor Of Oral And Maxillofacial Surgery -Cairo University, Egypt. Wbeialy@Yahoo.Com, Ahmed Abd Elsamad Associate Professor Of Oral And Maxillofacial Radiology– Cairo University, Egypt. Abdalsamad_A@Yahoo.Com, Ahmed Abozekry Lecturer Of Oral And Maxillofacial Surgery –Future University In Egypt, Egypt. Ahmed.Kamal@Fue.Edu.Eg

Future Dental Journal

Background: Maxillary sinus lifting is a complex procedure with reported complications in the literature where the presence of sinus septa further complicates the procedure, they including membrane perforation, bleeding. Aim: The aim of this study is to decrease the incidence of membrane perforation which is the most common reported complication, and to determine whether the use of surgical guides could decrease the incidence of membrane perforation. Materials and methods: A total of 12 cases where blindly divided into 2 groups; Group (A) computer guided maxillary sinus lifting and Group (B) conventional sinus lifting, both groups received allogenic bone blocks for …

Efficacy Of Preemptive Dexamethasone And Diclofenac On Pain Control During Maxillary Alveolar Ridge Horizontal Augmentation Using Cortical Shell Augmentation Technique: A Randomized Clinical Trial, Dina Ayman Fayek D.Ayman, Mohamed Mounir M.Mounir, Lobna Abdrlaziz Aly, Ahmed Abozekry

Future Dental Journal

Background: Despite the popularity and success of autogenous cortical shell augmentation, it is a painful procedure, limiting its acceptance by patients specifically if general anesthesia is not a viable option. Aim: This study assessed the analgesic efficacy of co-administration of intramuscular diclofenac sodium and dexamethasone preoperatively. Material and Methods: Patients selected according to the inclusion criteria were randomly divided into 2 equal groups. A similar surgical augmentation technique was performed in both groups using autogenous cortical shell technique. The study group received an intramuscular injection of dexamethasone and diclofenac sodium before surgery, and pain level was measured using VAS (visual …

Therapeutic Effect Of Curcumin, Ginger And Tamarind On Oral And Paraoral Tissues: (Histological Overview), Mona El Deeb, Amany A. Rabea

Future Dental Journal

Background: Biocompatible substances from plant origin have been more in focus in contemporary dentistry. Aim: This review, aimed to highpoint the influence of curcumin, ginger and tamarind on different oral and paraoral tissues from histological point of view. Material and methods: A narrative review was carried out based on publications in PubMed, google and Scopus database. The documents published up to 2021 were included. The research was based on inclusion criteria of 89 studies.Results: Curcumin inhibits alveolar bone resorption, reduces inflammatory cell infiltration, aids in epithelial regeneration and improves salivary glands architecture. Ginger was found to be beneficial in …

Analysis Of Changes In Gingiva-Occlusal Parameters As Perceived By Three Middle-East Population., Nadine Nachabeh, Tony Daher, Elie Maalouf Prof, Khalil Kharma, Eliane Kaydouh, Carina Mehanna

International Arab Journal of Dentistry

Purpose. This study aims to compare the effect of various smile parameters (buccal corridor, gummy smile, midline to face discrepancy, with and without upper lip filling) on the perception of smile attractiveness by applying the digital modification of images judged by laypersons from different Middle East populations.

Materials and Methods. One hundred and eighty participants are divided into 3 groups (n=60: 30 men and 30 women): Lebanese, Syrian, and Egyptian laypersons. A frontal photo of a woman's smile is manipulated with Photoshop to modify each smile parameter gradually into 3 grades. The total number of smiles assessed is 18.

In …

Recent Innovations And Technological Advancements In Dentistry And Medicine, Karthik Rajaram Mohan, Saramma Mathew Fenn, Ravikumar Pethagounder Thangavelu

International Arab Journal of Dentistry

The newer innovations play an important role in the earlier diagnosis of dental caries based on near-infrared transillumination imaging such as Diagnocam and Soprocare intraoral digital cameras, which aid in the diagnosis of dental caries and also differentiate old and newer dental plaques, respectively. Nanoparticles used as carriers for effective and targeted drug therapies in the treatment of rheumatoid arthritis of the temporomandibular joint (TMJ) and candidiasis among chronic denture wearers provided better-increased bioavailability than oral formulations. Artificial intelligence (AI) uses machines to simulate intelligent human behavior. Augmented reality has been presented as a cognitive extension of AI in health …

Compound Odontoma:Diagnosis And Treatment: Case Report, Georgina El Ghoule, Bassam Salameh, Wassim Al Manhal

International Arab Journal of Dentistry

Odontomas are an asymptomatic benign odontogenic tumors, generally discovered fortuitously, or when a tooth failed to erupt. They are mainly composed of enamel and dentin, cement and pulp tissue can also be present in variable amounts. In 2005, the World Health Organization classified two main types of odontoma, an amorphous and irregular mass of calcified dental tissues as complexe odontoma and multiple miniature tooth-like structures as compound odontoma. This article is a case presentation of a compound odontoma diagnosed for an eleven year old girl upon a routine radiography, making it a lesion of childhood /adolescence. A retro-alveolar radiography of …

Management Of Pulpal Floor Perforation Using Biodentinetm : Case Report, Chaima Bouhajja, Mayada Jemâa, Mohamed Bassem Khattech

International Arab Journal of Dentistry

During endodontic treatment in multi-rooted teeth, furcation perforation refers to an opening in the pulpal floor, leading to a communication with the periodontal ligament space. A three-dimensional hermetic seal, with a biocompatible material, is a key point for the success of pulp floor perforation repair. MTA® has been considered, for a long time, as a gold standard in furcation perforation repair. Besides, BiodentineTM, when used for the same purpose, showed considerable performance and good results. The purpose of this paper was to report the management of an iatrogenic perforation of pulpal floor in the maxillary right first molar, using BiodentineTM.

Root And Root Canal Morphology Of Premolars In A Sample Of The Lebanese Population: Clinical Considerations, Marie-José Merhej, Roula El Hachem, Hala Sacre, Pascale Salameh, Nabil Ghosn, Alfred Naaman

International Arab Journal of Dentistry

ABSTRACT

Objectives: The aim of this study was to investigate the anatomy of the maxillary and mandibular premolars among a sample of the Lebanese population and to explore their incidence by sex and the symmetry between the left and right sides. Materials and Methods: This retrospective analysis of 250 cone-beam computed tomography (CBCT) scans consisted of 960 maxillary and 972 mandibular premolars. Roots, canals, and morphology types were recorded. Vertucci’s classification was used to categorize the canal morphologies. Fisher’s exact and chi-square tests (P≤.05) were applied.

Results: The majority of maxillary first premolars had two roots (85.3%) with two …

Distal Cantilever Length Comparison In Esthetic Material For Hybrid Implant Prosthesis: An In Vitro Study., Sana Shams Eddin, Elie Jasser, Mohammad Chams Eddin, Carole Abi Ghosn Yared, Joseph Makzoumi, Paul Boulos

International Arab Journal of Dentistry

Objective: the assessment of distal cantilever length in implant supported infrastructure by comparing the load to fracture in two different framework esthetic materials (Zirconia and Polyetheretherketone (PEEK)) with two different cantilevers loading distances (10mm, 15mm). Material and methods: 20 frameworks were fabricated and divided into 4 groups (n=5): according to the material type Peek, zirconia, and according to the cantilever loading distance (10), or (15) mm and a load-to-fracture test was used until complete fracture of specimens occurs. Results: The effect of material type and cantilever loading distance were statistically significant for the mean load-to-fracture values (P< 0.05). The Zirconia group failed at higher fracture loads (817 N) than the Peek one (651 N). Frameworks with 10 mm cantilever loading distance failed at higher fracture loads than specimens with 15 mm. Conclusion: Peek is a suitable material for all-on-four framework reconstruction in specific situations, and there is a higher success rate when the distal cantilever length is kept at minimal value (10mm).

An Update Of Additive Manufacturing (3d Printing) Technology In Dentistry., Rami Saleh Al Fodeh, Ahed Al-Wahadni, Baker Otman, Mahmoud Almasri

International Arab Journal of Dentistry

Background:

The development of procedures known as additive manufacturing, which aim to produce more complex items with a lower overall material consumption compared to processes known as subtractive manufacturing. In addition, in recent years there has been a significant rise in the quantity of dental materials that are produced via the use of these techniques. As a consequence of this, scientific research has been concentrating more and more on such technologies, particularly in order to shed light on the methodology, indicators, and boundaries of the emerging technology.

Methods:

The purpose of this paper is to provide a narrative assessment of …

Effect Of Chlorhexidine On Nanoleakage And Bond Durability Of Two Adhesives To Dentin: An In Vitro Study, Rowayda Anwar Eltarawy, Essam Naguib, Ahmed Z. Elhoshy, Sara H. Younis

Future Dental Journal

Abstract

Aim: This study aimed to investigate the effect of chlorhexidine (CHX) on nanoleakage (NL) and dentin bond durability of two adhesives after water storage.

Materials and Methods: Thirty-six extracted molars were divided into three groups and their buccal surfaces were reduced to expose flat dentin surfaces. In group 1 Single Bond Universal Adhesive (SBU) was used, in group 2 Peak universal Bond (PUB) was applied while in group 3 Chlorhexidine Gluconate Disinfecting Solution followed by Single Bond Universal Adhesive (CHX+SBU) was used. Application of resin composite restorations was performed in all three groups. For each bonding procedure, …

Effect Of External Bleaching On Color Change Of Single Shade Resin Composite Versus Nano-Filled Resin Composite In Class V (In Vitro Study), Akram Gamal Diab, Essam Naguib, Ahmed Zoheir Elhoshy, Ahmed Mohamed Fouad

Future Dental Journal

This study investigated the effect of bleaching on color change of the single shade universal composite (Omnichroma) versus nano-filled resin composite (Z350 XT).

Methods: Twenty premolars of shade A3 were used for the study. Standardized class V cavities were prepared on the cervical third of the buccal surface of all teeth. After that, teeth were randomly divided into two groups of 10 teeth each according to the type of resin composite used. After composite application, all teeth were stored individually in distilled water for 24 hours. Evaluation of the restoration color was done using VITA Easyshade. The teeth were bleached …

Evaluation Of Color Difference And Translucency Of Modified Peek Restorations Veneered With Different Veneering Materials Before And After Thermal Cycling, Mohamed Hamdy Abdulmaguied, Tarek Salah Morsi, Mennatallah M. Wahba, Hesham Katamish

Future Dental Journal

Objective: The aim of this study was to investigate the effect of different PEEK veneering materials, as well as thermocycling on the color difference (ΔE) and the translucency parameter (TP) of modified PEEK veneered restorations.

Materials and Methods: Thirty disc shaped specimens of veneered BioHPP (1.5 mm X 12 mm) were randomly divided into three groups (n=10) based on the type of the veneering material. Group (A): Discs veneered with CAD milled Lithium Disilicate, group (B): Discs veneered with pre-cured milled composite, and group (C): Discs veneered with conventional light cured composite. CIELab values were calculated for all specimens over …

Correlating Parenting Style With Their Children’S Behavior, Dental Anxiety And Dental Caries During The First Dental Visit, Esraa Abdelfattah Khattab, Norhan Abd El-Wahab El-Dokky Professor Of Pediatric Dentistry & Dental Public Health, Randa Youssef Abd Al Gawad Professor Of Pediatric Dentistry & Dental Public Health

Future Dental Journal

Aim: Correlating parenting style with their children’s behavior, dental anxiety and dental caries during the first dental visit.

Methodology: A cross sectional study was conducted. Self-administered structured questionnaire ( PSDQ) contains 32 statements regarding different parent reactions to child behavior, and participants rated responses to each item using a five-point likert scale from “never” to “always” (coded 1 to 5).The target population consisted of 105 children with their parents in Faculty of Dentistry, Future University aged 3-6 years old. The highest mean score placed the parent in the proper parenting category. The child behavior was assessed using the Frankl scale …

Simultaneous 3d Reconstruction And Implant Placement Using Allogenic Laminar Bone Membranes In Atrophic Mandible. A Comparative Clinical Study, Sara T. Elshayat, Mohamed Diaa Zein El-Abdein, Waleed Ragab El Beialy, Waleed F. Esmael

Future Dental Journal

Objective: to compare the outcome of allogenic bone sheets clinically and radiographically in posterior mandibular vertical augmentation in Luhr class III cases with simultaneous implant placement using autogenous versus xenografts.

Patients and methods: this study was based on a total of 12 implants placed in 4 patients, 2 of which were males and 2 females. Patients were divided into 2 groups, both treated with implants placed with exposed threads 3 mm crestally and covered buccolingually with the laminar bone membrane; group 1 received autogenous bone obtained from the same surgical site using 4.5 diameter ACM bur mixed with PRP and …

Clinical And Radiographic Assessment Of Xenogenic Bone Graft With Or Without Hyaluronic Acid For Post Extraction Socket Preservation (Randomized Clinical Trial), Khaled Mohie Aldeen Abdelzaher, Lobna Abdel Aziz Aly Prof, Mostafa Ezz Prof., Mahmoud Mohsen Elsayed Hassan Elarini Dr.

Future Dental Journal

hyaluronic acid shows osteogenic potentials which considered important property during bone regeneration. So, we aim to assess the efficiency of hyaluronic acid with xenograft mixture in post extraction alveolar sockets to decelerate resorption of dental alveolar ridge.

Analysis Of Smile Characteristics Of Adult Female Subjects With Skeletal Class Ii Division 2 Malocclusion, Ahmed Ibrahim Nabawi, Fouad A. El Sharaby

Future Dental Journal

Aim: The objective of this study was to evaluate the smile characteristics of adult females with Angle Class II division 2 malocclusion compared to Angle Class I malocclusion. Materials and Methods: Two frontal photographs were taken for 30 orthodontically untreated female adult subjects with age range (18-30) years, at rest and posed smile from a fixed (1.5m) distance between the camera and the subjects. The 30 subjects were divided into 2 groups, 15 for Class II div 2 subjects and 15 for Class I subjects. The camera was focused only on the mouth, showing from the nose to the chin. …

Effect Of Low-Level Diode Laser Bio-Stimulation On Implant Stability Before, During And After Immediate Implants In Mandibular Molars. (A Randomized Clinical Study), Ahmed Elsayed Fahim A.Faim, Ahmed Farid Shehab, Waleed Ragab El-Beialy, Ahmed Abozekry

Future Dental Journal

Introduction: Tooth loss can affect the person’s life dramatically. Tooth loss is accompanied by bone loss in all dimensions, so preservation of the bone is mandatory for placement of dental implant.

Immediate implant can preserve alveolar bone. Due to difference in shape between the implants and extracted roots a gap appears between the immediately placed implant and the extraction socket resulting in jumping distance, Bone grafts are commonly used to fill this gap, recent studies suggest that jumping gaps shouldn’t always be grafted.

Low level bio stimulation has stimulatory effect on bone cells so it can be used in immediate …

Evaluation Of Apoptotic Effect Of Betanin Nanoparticles Against Squamous Cell Carcinoma Cell Line Compared To Doxorubicin, Noha Hassanine Noha.Hassanine@Fue.Edu.Eg, Future University In Egypt, Amany M. Taha Lecturer, Al Azhar University, Egypt, Eman A. Abohager Professor, Al Azhar University

Future Dental Journal

Objective : to evaluate the anticancer effect of nano sized betanine particles (betanine NP) on squamous cell carcinoma cell line compared to doxorubicin (DOX) by measuring apoptosis through caspase 3. Methods: Three groups of the human tongue squamous cell carcinoma cell line (SCC 25) were created, and two of them were treated with DOX and betanine NP. The third group served as a negative control and was not given any treatment. To evaluate the concentration of caspase 3 using the ElISA technology, different quantities of betanin NP and DOX were administered to SCC25 at 48- and 72-hour intervals.Results: …