Psychiatry and Psychology Commons^™

Maternal Depressive Symptoms Predicting Development Of Internalizing Behavior Problems In Boys With Fragile X Syndrome, Sara Deal, Mary Blair Dellinger

Caravel Undergraduate Research Journal

Individuals with fragile X syndrome (FXS) often exhibit increased internalizing problem behaviors that substantially impact functioning. Research suggests that maternal depressive symptoms can increase the development of internalizing problem behaviors in their children. The present study examined whether (1) maternal depressive symptoms related to the degree of internalizing behaviors exhibited in their sons with FXS, and (2) age as an influencing factor for the development of internalizing behaviors. Child internalizing behaviors were measured in 49 male children with FXS (range 1.08-5.75 yrs). Maternal depressive symptoms were measured in each of their mothers with the FMR1 premutation (range 20.55-40.74 yrs). Increased …

Feeding The Future: Prenatal Dietary Effects On Offspring Neurodevelopment, Emma Whatley

Senior Honors Theses

This study examined the effects of prenatal Western (WD) and Mediterranean (MD) diets on offspring metabolic, cognitive, and neurobiological outcomes in a preclinical mouse model. Working and long-term memory performance, dendritic morphology, and gene expression were assessed using behavioural tests (CAL, YMRM, WM) and Golgi-Cox analyses. Behavioural effects were minimal, with female MD offspring showing improved memory performance under standard conditions. Metabolic findings showed effects on body weight and blood glucose. Dendritic morphology was largely unchanged; however, subtle, sex-specific differences were observed. Differential gene expression between MD and WD suggests a role for future environmental stressors. Prenatal diet affects molecular …

I Lost My Number, Can I Have Yours? Body Image Satisfaction With Sexually Dimorphic Traits Is Associated With Men's Dating Anxiety And Confidence, David A. Frederick, Tania A. Reynolds, Nikoline L. Smart, Justin R. Garcia, David A. Puts

Psychology Faculty Articles and Research

Evolutionary scientists posit that sexual selection processes caused males to develop sexually dimorphic traits to aid them during intrasexual competition and increase their likelihood of being chosen as mates. Evolutionary social sciences have extensively examined women's preferences for traits such as muscle mass and voice pitch, reasoning that these traits serve as cues of men's ability to provide direct benefits (e.g., resources) and indirect (genetic) benefits passed on to offspring. At the same time, body image researchers have extensively focused on the social causes and consequences of men's dissatisfaction with their muscularity and body fat. We connected these two research …

The Intersection Between Adolescent Pregnancy, Mental Health Concerns, Stigma, And Sex Education, Madelon Cox

Honors Program: Senior Projects (Public)

This thesis discusses research from the past two decades focused on factors contributing to an increased risk of adolescent pregnancy and the lasting impact of that pregnancy. The consequences of being a pregnant adolescent can be compounded by race, gender, socioeconomic class, and access to education. Adolescent pregnancy also carries significant physical and mental health risk for the adolescent and the child. Awareness and various interventions can help pregnant adolescents or those who may be at risk for adolescent pregnancy to support them, prevent isolation, and reduce further negative mental health conditions, such as depression and anxiety.

Oxytocin-Mediated Trust Formation In Relationship-Based Sales, Isabella G. Farrington

Biological Sciences Undergraduate Honors Theses

Trust is a critical driver of success in relationship-based sales, particularly in complex environments such as medical, pharmaceutical, and B2B markets where decisions involve uncertainty, risk, and long-term commitment. Existing research in marketing and psychology primarily explains trust through interpersonal behaviors, communication, and relationship management strategies. However, the biological mechanisms underlying trust formation remain largely underexplored in these contexts.

This thesis examines the role of oxytocin, a neuropeptide associated with social bonding and cooperation, in shaping trust and decision-making in professional sales environments. Drawing on research from neuroscience, neuroeconomics, and relationship marketing, it proposes that oxytocin-mediated processes provide a biological …

The Influence Of Valence On Action Control: A Comparison Of Simon Effects In The Extrinsic Affective Simon Task (East) And The Spatial Simon Task, Yaara Aleissa

College of Arts & Sciences Senior Theses

People adjust their thoughts and actions in response to a changing environment every day and emotions may influence these actions. Understanding how emotion impacts action control in situations where emotion is central to the action (task-relevant) compared to when it is present in the environment as distracting information (task-irrelevant) is essential. Currently it is unclear when emotion most significantly modulates action control. This study seeks to compare how valence (positive versus negative emotion) impacts action control performance when valence is task-relevant and task-irrelevant by using two modified versions of the Simon conflict task.

The Simon task is a paradigm to …

Evaluating Spect Neuroimaging In Psychiatric Diagnosis: A Critical Review And Proposed Randomized Controlled Study, Kiley Carter

Senior Honors Theses

Mental illness affects a substantial proportion of adults in the United States, yet psychiatric diagnosis remains subject to diagnostic variability. Single-photon emission computed tomography (SPECT) is a neuroimaging technique that measures cerebral blood flow and has been proposed as an adjunctive tool for psychiatric evaluation. Existing literature reports group-level perfusion patterns associated with certain psychiatric conditions, suggesting potential utility in diagnosing complex or treatment-resistant cases. However, critics of SPECT emphasize the absence of randomized controlled data demonstrating improved patient outcomes. To address this gap, a prospective randomized controlled trial comparing standard psychiatric care with SPECT-guided evaluation is proposed. The proposed …

Cultural Adaptation Of A Single Session Acceptance And Commitment Therapy Guide For College Students In Uganda, Miriam Mukasa Kasozi

All Graduate Theses and Dissertations, Fall 2023 to Present

Mental health problems such as depression, anxiety, and stress are common among Ugandan university students and can make it difficult for them to succeed in school or maintain well-being. However, many students do not have access to professional mental health care. Digital self-help programs can make support more available, especially when they are designed to fit the local culture and context. This project examined how an online program called ACT Guide Lite, which teaches skills from Acceptance and Commitment Therapy (ACT), could be adapted for use with Ugandan college students. Students and other university community members first completed the program …

The Rodent Electronic Nicotine Delivery System (Rends): Effects Of Age On Self-Administration Of Inhaled Nicotine In Female Rats, Daniel Santos Da Silva

All Graduate Theses and Dissertations, Fall 2023 to Present

Smoking tobacco is the leading avoidable cause of death and drives many health problems. Nicotine, the main chemical in tobacco products, keeps people using it. This study used the Rat Electronic Nicotine Delivery System (RENDS), an inexpensive and freely shared, to examine e-cigarette use in adolescent and adult female rats by exploring four phases of nicotine delivered and not delivered to understand use patterns among ages. Our study found that both adolescent and adult female rats chose to inhale nicotine when given the opportunity, showing drug-seeking behavior. Overall, nicotine use was similar between ages. These results could help inform therapies, …

Navigating New Environments: Acculturative Stress And Substance Use Among International Vs Domestic Students From Latino/A Backgrounds, Madelyn R. Null

Psychological Science Undergraduate Honors Theses

College students can experience a range of cultural and social pressures that could relate to their alcohol and cannabis use. Latino/a international students may face unique challenges as they adjust to campus environments in the United States (U.S.), yet little research has compared their substance use patterns to those of Latino/a domestic students. Therefore, the present study aims to examine whether: (a) Latino/a international and domestic students differ in their alcohol use, (b)they differ in their cannabis use, and (c) acculturative stress moderates the relationship between international student status and these substance use behaviors. Latino/a undergraduates (n=440; Mage=20.55; female=71%; international=21%) …

Choosing Death: The Moral Legitimacy Of Voluntary Active Euthanasia, Emma Rougeou

Honors Theses

During the last three decades, the issue of physician assisted suicide has captivated the interest of private citizens and state legislatures. Thinking about the matter of end-of-life concerns, particularly surrounding euthanasian (practices that hasten the deaths of suffering terminally ill people) have shifted. Views of private citizens and state-level legislation reflects a “slow shift to more permissive attitudes” (Cohen et al., 2012). Meanwhile, as recently as March 2026, state legislators in conjunction with the NY State Governor, passed a bill legalizing medical aid in dying for terminally ill patients. This thesis is intended to thoughtfully contribute to meaningful discourse on …

Neuroprotective Effects Of Prophylactic Brivaracetam On Memory And Anxiety Following Traumatic Brain Injury, Sofia Dumic

Theses and Dissertations

Prophylactic brivaracetam (BRV) was evaluated in a rat TBI model for effects on behavior and serum tau. BRV reduced anxiety-like behavior with optimal dose-dependent effects at 2.1mg/kg, but did not affect working memory. Serum tau was detectable early post-injury, supporting its use as a biomarker.

Probing The Roles Of Connexin 43 Hemichannels In A Mouse Model Of Alzheimer's Disease, Madison Treasure-Areno

All Graduate Theses and Dissertations, Fall 2023 to Present

Alzheimer’s disease is a progressive disorder involving neuronal death and cognitive decline, such as memory loss and changes in personality. One feature of the disease is buildup of abnormal protein called amyloid-beta in the brain. Amyloid-beta may activate support cells called astrocytes, triggering them to release large amounts of chemicals, possibly harming nearby cells. This study set out to examine the roles of the channels on astrocytes involved in releasing these chemicals, called connexin 43 hemichannels. Using a mouse model of Alzheimer’s disease, this study blocked the hemichannels using the drug Tonabersat, and measured spatial learning and memory in a …

Relationship Between Disordered Eating Behaviors And Sport In Female Collegiate Athletes, Elizabeth Files

General Human Environmental Sciences Undergraduate Honors Theses

Disordered eating behaviors and body image concerns remain prevalent among collegiate athletes, yet the role of sport type and sport-related environmental factors, such as uniforms, is not fully understood. The purpose of this study was to examine the relationship between sport type, uniform perception, and disordered eating behaviors among female collegiate athletes at the University of Arkansas. A quantitative, non-experimental design was used, with 36 athletes completing an anonymous Qualtrics survey incorporating demographic questions, uniform perception items, and the Eating Disorder Examination Questionnaire Short Form (EDE-QS).

Descriptive analyses indicated a predominantly young (ages 18–21), White, and underclassman sample. Chi-square analyses …

Prefrontal Engagement In Cognitive Flexibility Across Paradigms, Katarina Kalajzic

Honors Scholar Theses

Cognitive flexibility is an executive function that involves dynamically adapting behavior in the face of changing environmental circumstances to achieve a particular goal. Disrupted in numerous psychiatric disorders such as Alzheimer’s disease, schizophrenia, OCD, and depression, the neural correlates of cognitive flexibility are not well understood. However, the prefrontal cortex (PFC) is strongly implicated in executive function and attentional control processes. Thus, we sought to examine the neural circuitry involved in distinct cognitive flexibility tasks – the attentional set-shifting task and the probabilistic 2-armed bandit task. Through optogenetic suppression, we targeted pyramidal neurons of the rodent medial prefrontal cortex, an …

Feasibility Of Assessing Dietary Patterns And Anxiety In College Students: A Pilot Study Using Nutrition Questionnaires, Gad-7, And Asq, Kylie Ford

Electronic Theses and Dissertations

Anxiety is highly prevalent among college students representing a significant public health concern. Research indicates that dietary patterns may influence mental health outcomes; however, the practicality of collecting comprehensive dietary and psychological data in college populations remains unclear. This pilot study assessed the feasibility of evaluating dietary patterns and anxiety using self-report instruments. Participants completed the Nutrition and Eating Habit questionnaire, the Generalized Anxiety Disorder-7 (GAD-7), and the Anxiety Sensitivity Questionnaire (ASQ). Although twenty-one students were recruited, survey completion rates were low, with only seven participants completing the nutrition questionnaire necessary to calculate the Dietary Inflammatory Index (DII). Descriptive analyses …

Platelet Gαz Regulates Ovarian Tumor Growth And Mediates The Effects Of Chronic Stress, María G. Torres Carrizalez

Dissertations and Theses (Open Access)

Ovarian cancer is the most aggressive gynecologic cancer, with 12,450 estimated deaths in 2026. Elevated platelet counts are commonly observed in patients with ovarian cancer and are associated with enhanced tumor growth and poor prognosis. Patients with ovarian cancer are frequently exposed to elevated levels of stress, which has been correlated with accelerated disease progression and increased mortality. Interestingly, the platelet Gαz protein is activated by epinephrine through the α2A-adrenergic receptor, suggesting a potential mechanistic link between stress signaling and platelet-driven tumor progression. To investigate this, I evaluated the role of platelet Gαz in ovarian cancer using control (Gz^{fl/fl …}

Big Feelings, Fast Decisions: Emotion Regulation As A Moderator Of Impulsivity In Binge And Emotional Eating, Emma G. Folk

Graduate Theses and Dissertations (2019 - present)

Emotion-driven impulsivity and difficulties with emotion regulation are both associated with maladaptive eating behaviors, including binge eating and emotional eating. However, it remains unclear whether broader emotion regulation difficulties intensify the influence of impulsive responses to emotional states on these behaviors. This study examined whether emotion dysregulation moderates the relationship between emotion-driven impulsivity and maladaptive eating behaviors. Participants were 266 adults (ages 18–65) who completed measures of impulsivity, emotion regulation difficulties, binge eating, and emotional eating. Moderation analyses were conducted using PROCESS in SPSS, controlling for body mass index (BMI) and gender. Negative and positive urgency were significantly associated with …

The Mysteries Of Postpartum Ocd: A Systematic Review, Taryn Shaffer

Honors Program: Senior Projects (Public)

Background: The research on postpartum mental health is growing, with most focusing on physical and sexual wellness, or well-known mental health symptoms such as psychosis, depression, and stress. However, as the research grows, so does the interest in lesser-known or under-considered postpartum mental health symptoms, including Obsessive-Compulsive Disorder (OCD). The focus of this research can be the exacerbation of already-present OCD symptoms, or the onset of them during pregnancy and the postpartum period. The purpose of this systematic review was to analyze research on OCD in pregnant and postpartum women. Specifically, the review included an analysis of measures used to …

Social Correlates Of Trauma And Posttraumatic Stress Disorder: The Importance Of Context, Lukoye Atwoli, Linnet Ongeri

Internal Medicine, East Africa

Understanding trauma and posttraumatic stress disorder (PTSD) requires a contextual perspective that considers historical legacies, social environments, and cultural realities. This paper draws on empirical evidence from Kenya and Uganda to demonstrate the limitations of applying trauma frameworks developed in high-income countries to African contexts. Findings from the Orphaned and Separated Children’s Assessment Related to Their Health and Well-Being (OSCAR) study challenge assumptions about care environments. The study reveals higher PTSD rates among orphans in family-based settings compared to institutional care, and highlights the protective roles of religion and social support. The Neuropsychiatric Genetics of African Populations-Psychosis (NeuroGAP-Psychosis) study provides …