Psychiatry and Psychology Commons^™

Predictors And Diagnosis Of Adjustment Disorder In A Middle-Aged Patient With Cholangiocarcinoma, Zoya Gurm, Abbie R. Bauer

Clinical Research in Practice: The Journal of Team Hippocrates

A clinical decision report using:

Hund B, Reuter K, Härter M, et al. Stressors, Symptom Profile, and Predictors of Adjustment Disorder in Cancer Patients. Results from an Epidemiological Study with the Composite International Diagnostic Interview, Adaptation for Oncology (CIDI-O). Depression and Anxiety. 2016;33(2):153. https://doi.org/10.1002/da.22441

for a patient with recently diagnosed solid tumor malignancy.

Effect Of Patient Resilience On Functional Outcomes After Meniscectomy, Adeeb Hanna, Andres Perez, Alice He, John Sonnier, Henson Destine, Rahul Muchintala, Ralph Cook, Sean Bryan, Fotios Tjoumakaris, Kevin Freedman

Rothman Institute Papers

BACKGROUND: Recent literature has identified that patient resilience may affect outcomes after meniscectomy. Research into psychological risk factors for poor surgical outcomes has been a focus in orthopaedic surgery.

PURPOSE/HYPOTHESIS: The purpose of this study was to examine the relationship between preoperative patient resilience and 2-year postoperative outcomes after arthroscopic meniscectomy. It was hypothesized that there would be no relationship between resilience and patient-reported outcomes after meniscectomy.

STUDY DESIGN: Cohort study; Level of evidence, 2.

METHODS: Patients who underwent meniscectomy between January and June 2020 at a single multicenter institution were identified, and those aged ≥18 years without evidence of …

Modulation Of Energetic And Lipid Pathways By Curcumin As A Potential Chemopreventive Strategy In Human Prostate Cancer Cells, Michele Pellegrino, Maria Antonietta Occhiuzzi, Fedora Grande, Ilaria Stefania Pagani, Stefano Aquaro, Paola Tucci

Staff and Researcher Publications

In Western industrialized countries, prostate cancer (PCa) is the second most common malignant disease and prevalent cause of death for men. Epidemiological studies have shown that curcumin (CUR) either prevents PCa initiation or delays its progression to a more aggressive and treatment-refractory form, thus reducing related mortality. Our previous studies have proven the anticancer, antioxidant, and anti-inflammatory properties of CUR on PCa cells. However, there are few reports of the effect of CUR on energy and lipid pathways in PCa. Herein, we show that CUR can modulate the two metabolic energy pathways, increasing glycolytic reserve and reducing oxidative phosphorylation. Moreover, …

A Call To Study The Bidirectional Relationship Between Healthcare Accessibility Issues And Medical Gaslighting For Marginalized Groups With Chronic Pain, Nikki Harnage

Honors College Theses

Chronic pain is an epidemic in its own right. Affecting 21% of American adults and costing $300 billion each year, chronic pain rivals cancer, diabetes, and hypertension combined. From psychological impacts on patients to worsening health outcomes further burdening the healthcare system and billions of lost productivity stressing the economy, chronic pain can affect all Americans. However, chronic pain disproportionately afflicts marginalized groups including non-whites, women, and disadvantaged socioeconomic classes. For decades, research has demonstrated disparities in diagnosis, treatment, and management of chronic pain are associated with accessibility issues in healthcare, a link that is likely the result of systemic …

Difficult To Treat Depression: Focus On Approach, Algorithms, And Access, Jordan F Karp, Roberta D Brinton, Jay C Fournier, Lisa Harding, Manish K Jha, Eric J Lenze, Sanjay J Mathew, Samantha Meltzer-Brody, David C Mohr, Patricio Riva-Posse, Ilse Wiechers, Nolan R Williams

Staff and Researcher Publications

The pandemic refocused interest on the burden of depression across the lifespan; the increased efforts to prevent and treat depression are now a priority of health care systems, insurers, patient advocates, digital therapeutic engineers, telemedicine platforms, and community health agencies. However, the challenges of treating depression to remission in adult patients who do not respond to first, second, or third levels of oral pharmacotherapy remain. The increased prevalence of these conditions is at odds with the shrinking psychiatric workforce. Since addressing difficult to treat depression is situated in a rapidly evolving treatment landscape, The University of Arizona College of Medicine-Tucson …

Additive Value Of A Reinforcer Preference Assessment In Elementary Classroom Group Contingencies, De'vohn J. Roman

USF Tampa Graduate Theses and Dissertations

Disruptive behavior in elementary classrooms can hinder students' academic engagement and overall learning experience. This study examined the effectiveness of using a student-selected reinforcer preference assessment in a positive variation of the Good Behavior Game, a widely implemented classroom management strategy, in general education elementary classrooms. The study's purpose was to determine whether student-selected reinforcers led to better outcomes compared to teacher-selected reinforcers, by examining the intervention's effects on academic engagement and disruptive behavior. The methodology involved a single-case research design and an alternating treatment design, which were employed to answer the research questions. Findings revealed the benefits of integrating …

Administration Patterns Of Magnesium Sulphate For Women With Preeclampsia And Immediate Newborn Outcomes In Kawempe National Referral Hospital-Uganda: A Cohort Study, Christopher J. Burant, Shirley Moore, Carol Blixen, Martha Sajatovic

Faculty Scholarship

Background: Preeclampsia is the second leading cause of maternal death in Uganda. WHO recommends using magnesium sulphate (MgSO4) to prevent and treat preeclampsia with severe features (PEC) and eclampsia. MgSO4 is used to prevent eclampsia and treat women who experience an eclamptic convulsion to avoid severe maternal/infant illnesses and death. We set out to assess MgSO4 administration patterns in women with PEC or eclampsia and the immediate newborn outcomes of neonates. Methods: This was an analytical observational cohort study at Kawempe National Referral Hospital in Uganda. Two hundred ten pregnant mothers with PEC or eclampsia were recruited in the study …

Exploring Mental Health Providers' Willingness To Integrate Digital Applications For Gen-Z Students, Chanlinee Karawek

Undergraduate Research Symposium Lightning Talks

Mental health services have expanded significantly throughout recent years, alongside the virtualization of said services since the COVID-19 pandemic. As a result, digital mental health applications (DMHAs) are now widely available. Generation-Z college students are a demographic that both grew up with this technology and is associated with a high risk of mental illness development during their time in higher education. Integration of familiar technology and necessary mental health services could potentially help address their unique psychological needs. This study explores mental healthcare providers’ perspectives on incorporating DMHAs into their therapy services to Gen-Z college students. An anonymous survey was …

Improving Healthcare Utilization Models And Uncovering Health Behavior Patterns In Asian Americans Through Data Disaggregation, Luke Cho

Undergraduate Research Symposium Podium Presentations

Although Asian Americans are made up of 20+ distinct ethnicities with unique health outcomes, previous healthcare research has treated them as a monolithic group, covering up many important disparities in health outcomes and healthcare utilization patterns. This study examines how disaggregating Asian American health data by ethnicity improves models analyzing healthcare utilization patterns, focusing on routine physicals, dental checkups, alternative medicine consultations, and preference for ethnic concordance.

Using data from the 2015 Asian American Quality of Life survey (2,609 adults in Austin, Texas), binomial generalized linear models (GLMs) analyzed the impact of income, age, gender, insurance status, and ethnicity on …

Moving From Traits To The Dynamic Process: The Next Steps In Research On Human Resilience, Yannick Hill, Michael L. Dolezal, Patric C. Nordbeck, Ruud J. R. Den Hartigh, David Pincus, Adam W. Kiefer, Bernard P. Ricca

Psychology Faculty Articles and Research

The current literature on resilience shows a trend toward a dynamic process conceptualization, moving away from the previous trait-approach. However, the term “dynamic” is increasingly treated as a buzzword and is thereby oversimplified in the literature. The aim of this article is to develop a unified language pertaining to resilience as a dynamic process, so as to ensure progress in this field. First, we briefly introduce the traditional trait approach alongside the implicit assumption on which it is built. Next, we contrast this approach by discussing what dynamics entail and how this approach differs from mainstream psychological approaches. Specifically, dynamics …

The Influence Of Sociodemographic, Tobacco Use, And Mental Health Characteristics On Treatment Adherence Among Adults Enrolled In A Community-Based Tobacco Cessation Program, Motolani E. Ogunsanya, Summer G. Frank-Pearce, Sixia Chen, Munjireen Sifat, Amy M. Cohn, Michael S. Businelle, Darla E. Kendzor

Kimmel Cancer Center Faculty Papers

BACKGROUND: While counseling and pharmacological interventions are known to facilitate smoking cessation, poor adherence can impact their effectiveness. Therefore, this study aimed to identify personal and clinical factors that influenced adherence to smoking cessation treatment among socioeconomically disadvantaged adult Oklahomans enrolled in a publicly available tobacco treatment program and observational research study.

METHODS: Adult participants (N = 442) were enrolled in a community-based tobacco treatment program. Logistic regression models identified sociodemographic, mental health, and substance use characteristics associated with treatment adherence. Adherence was measured by counseling session attendance and weeks of moderate/high medication adherence assessed via the Medication …

Is Warmer Better? Examining Counseling Student Responses To Syllabus Tone, Angela I. Sheely-Moore, Leeann Cardaciotto, Krista Malott, Megan Krell, Carlos A. Flores

Journal of Counselor Preparation and Supervision

Researchers in this quantitative study explored the impact of syllabus tone on master-level counseling students (N = 124). Findings indicate statistically significant differences between students’ reactions to syllabi language, with greater student retention of the content within the warm syllabus condition and more favorable perceptions of the instructor and their grading practices. Implications for counselor educators are included.

Identifying Barriers To Hepatitis B And Delta Screening, Prevention, And Linkage To Care Among People Who Use Drugs In Philadelphia, Pennsylvania, Usa, Beatrice Zovich, Catherine Freeland, Holly Moore, Kara Sapp, Anousha Qureshi, Amy Jessop, Rachel Holbert, Fiona Borondy-Jenkins, Quinn Plunkett, Chari Cohen

Student Papers, Posters & Projects

BACKGROUND: People who use drugs (PWUD) are at increased risk for blood-borne viruses, including hepatitis B (HBV) and delta (HDV). Despite the public health threats both viruses present, awareness remains low among at-risk communities and providers who serve them. This study assessed barriers to HBV and HDV prevention, diagnosis, and linkage to care, evaluated existing levels of knowledge, and identified educational needs and preferences among both PWUD and service providers.

METHODS: For this mixed-methods study, data were collected through an anonymous online provider-focused survey, and interviews with PWUD, non-medical staff, and healthcare providers at a harm reduction organization in Philadelphia, …

Acute Stress Activates Basolateral Amygdala Neurons Expressing Corticotropin-Releasing Hormone Receptor Type 1 (Crhr1): Topographical Distribution And Projection-Specific Activation In Male And Female Rats, Robert J. Aukema, Gavin N. Petrie, Samantha L. Baglot, Nicholas W. Gilpin, Matthew N. Hill

School of Medicine Faculty Publications

Although the basolateral amygdala (BLA) and corticotropin releasing hormone receptor type I (CRHR1) signaling are both central to the stress response, the spatial and circuit-specific distribution of CRHR1 have not been identified in the BLA at a high resolution. We used transgenic male and female CRHR1-Cre-tdTomato rats to topographically map the distribution of BLA neurons and identify whether they are activated by acute stress. Additionally, we used the BLA circuits projecting to the central amygdala (CeA) and nucleus accumbens (NAc) as a model to test circuit-specific expression of CRHR1 in the BLA. We established several key findings. First, CRHR1 had …

Driving Healthy Behaviors Through Social Support: The Role Of Co-Responsibility In Weight Loss And Maintenance, Melanie Knufinke-Meyfroyt, Carlo Lancia, Yentl Lodewijks, Simon Nienhuijs, Eva Deckers

Patient Experience Journal

Objective: The effectiveness of out of hospital lifestyle interventions in healthcare is likely co-dependent on social support from involved one's. We sought to investigate the interrelationships between patient-partner Co-responsibility, Spousal Support, and Self-efficacy and the mechanisms through which they contribute to health behaviors and outcomes relevant to weight loss and maintenance. Methods: Co-responsibility, Spousal Support, self-efficacy, health outcomes and health behaviors like total weight loss, physical activity, OBESI-Q, and health satisfaction were assessed through a questionnaire among 868 individuals attempting to lose weight. Full and semi-partial correlations were used to understand the association between Co-responsibility, Spousal Support, Self-efficacy …

The "Ableism'' Behind Mental Health Professionals' Perceptions Of Support, Hideki Muramatsu

Patient Experience Journal

This paper presents the personal narrative of the author, an individual who has experienced personal and clinical recovery from mental health difficulties. Diagnosed with a mental disorder (NEUROTIC; ICD-10) during my university years, I endured cognitive dysfunction, panic disorder, derangement of ego, suicidal ideation, and depression. Despite these challenges, I have actively engaged in social skills training, supervised virtual reality content, led self-help groups, and published papers on my experiences. I will discuss my own experiences as an expert-by-experience and describe the tendencies of professional ableism consciousness that I encountered during my journey of recovery. Through the lens of my …

Knowledge, Attitudes, And Concerns About Psilocybin And Mdma As Novel Therapies Among Us Healthcare Professionals, Erin Wang, David S Mathai, Natalie Gukasyan, Sandeep Nayak, Albert Garcia-Romeu

Center for Medical Ethics and Health Policy Staff Publications

Psychedelic-assisted therapy (PAT) with substances like psilocybin and MDMA has shown promise for conditions including depression and post-traumatic stress disorder. Psilocybin and MDMA may become approved medicines in the coming decade. This study assessed knowledge and attitudes regarding PAT among 879 U.S. healthcare professionals via anonymous online survey. Multivariable linear regression was used to identify predictors of openness to clinical use. Most participants (71.2%) were female and White (85.8%), with a mean (SD) age of 45.5 (12.7) years. Registered nurses (25.4%) and physicians (17.7%) comprised the largest professional groups. Respondents endorsed strong belief in therapeutic promise, and moderate openness to …

Association Between Motor Tests And Antiretroviral Medication Adherence In Older Adults With Hiv, Priyanka Ramanathan, Romil Pitale, Curtis Ko, Pranav Uppalapati, Viraj Padhiar, Bobby Bajwa, Raymond Ownby

HCA-NSU MD Research Day

Objective: This study evaluated measures of motor performance as predictors of medication adherence in older adults with HIV infection. Background: Patient adherence to HIV treatment is crucial for optimal clinical outcomes. Factors such as the complexity of drug regimens and financial constraints make ideal adherence difficult. While strategies promoting adherence exist, there is a lack of research on screenings that predict adherence. Previous research suggests motor performance is correlated with adherence but has not been extensively studied in older individuals. The integration of motor assessments into screenings of medication adherence may help to improve outcomes. Methods: Data were drawn from …

Predictors Of Study Dropout In Cognitive-Behavioural Therapy With A Trauma Focus For Post-Traumatic Stress Disorder In Adults: An Individual Participant Data Meta-Analysis, Simonne Wright, Eirini Karyotaki, Pim Cuijpers, Jonathan Bisson, Davide Papola, Anke B Witteveen, Sudie E Back, Dana Bichescu-Burian, Liuva Capezzani, Marylene Cloitre, Grant J Devilly, Thomas Elbert, Marcelo Mello, Julian D Ford, Damion Grasso, Pedro Gamito, Richard Gray, Moira Haller, Nigel Hunt, Rolf J Kleber, Julia König, Claire Kullack, Jonathan Laugharne, Rachel Liebman, Christopher William Lee, Jeannette Lely, John C Markowitz, Candice Monson, Mirjam J Nijdam, Sonya B Norman, Miranda Olff, Tahereh Mina Orang, Luca Ostacoli, Nenad Paunovic, Eva Petkova, Patricia Resick, Rita Rosner, Maggie Schauer, Joy M Schmitz, Ulrich Schnyder, Brian N Smith, Anka A Vujanovic, Yinyin Zang, Érica Panzani Duran, Francisco Lotufo Neto, Soraya Seedat, Marit Sijbrandij

Faculty, Staff and Student Publications

Background: Available empirical evidence on participant-level factors associated with dropout from psychotherapies for post-traumatic stress disorder (PTSD) is both limited and inconclusive. More comprehensive understanding of the various factors that contribute to study dropout from cognitive-behavioural therapy with a trauma focus (CBT-TF) is crucial for enhancing treatment outcomes.

Objective: Using an individual participant data meta-analysis (IPD-MA) design, we examined participant-level predictors of study dropout from CBT-TF interventions for PTSD.

Methods: A comprehensive systematic literature search was undertaken to identify randomised controlled trials comparing CBT-TF with waitlist control, treatment-as-usual or another therapy. Academic databases were screened from conception until 11 January …

The Effects Of Intersectional Identity Affirmation On The Relationship Between Racist Or Heterosexist Microaggressions And Mental Health For Lgbtq+ People Of Color, Kevin J. Chi, Joshua G. Parmenter, Renee V. Galliher

Psychology Student Research

Lesbian, gay, bisexual, transgender, and queer (LGBTQ+) people of colour (POC) live at the intersection of multiple marginalised statuses. While previous literature has linked positive, affirmed identity with better mental health for LGBTQ+ individuals, identity affirmation may be compromised by intersecting systems of oppression. This study 1) investigated how multiple intersecting forms of oppression (i.e. racism within LGBTQ+ communities and heterosexism within ethnoracial communities) relate to anxiety and depression for LGBTQ+ POC, and 2) examined the indirect effects of intersectional microaggressions on mental health through identity cohesion. A subsample of participants who identified as both a member of the LGBTQ+ …