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Igf-1 As A Biomarker For Symptom Severity In Adult Traumatic Brain Injury: Evidence From An Observational Study, Justin Weppner, Kimberly Rosenthal, Jennifer Bath, Tonja Locklear, Melissa Martinez 2025 Virginia Tech Carilion School of Medicine

Igf-1 As A Biomarker For Symptom Severity In Adult Traumatic Brain Injury: Evidence From An Observational Study, Justin Weppner, Kimberly Rosenthal, Jennifer Bath, Tonja Locklear, Melissa Martinez

Department of Physical Medicine & Rehabilitation Faculty Publications

Traumatic brain injury (TBI)-related growth hormone deficiency is often undertreated, despite documented physical, metabolic, and neuropsychiatric effects. Insulin-like growth factor (IGF-1), with neuroreceptors located in brain regions responsible for learning, memory, and mood, regulates cerebral blood flow, neurogenesis, and neuroplasticity. The aim of this study was to determine associations between IGF-1 levels and post-TBI symptom severity, anxiety, and depression. This retrospective observational study at an Academic Brain Injury Center included participants evaluated 3-12 months post-TBI with available IGF-1 values and complete Rivermead Post-Concussion Symptoms Questionnaire (RPQ-13), Generalized Anxiety Disorder-7 (GAD-7), and Patient Health Questionnaire-9 (PHQ-9) responses. Patients under 18 or …


Resilience And Reality: Exploring The Lived Experiences Of People Living With Hiv In Texas During The Covid-19 Pandemic – A Qualitative Study., Ahmed F. Alanazi 2025 The University of Texas at Arlington

Resilience And Reality: Exploring The Lived Experiences Of People Living With Hiv In Texas During The Covid-19 Pandemic – A Qualitative Study., Ahmed F. Alanazi

Social Work Dissertations - Archive

This study investigated the lived experiences of individuals living with HIV (PLWH) in the Dallas-Fort Worth (DFW) area of Texas during the COVID-19 pandemic, using an Interpretative Phenomenological Analysis (IPA) framework. The research examined the intersection of health, social dynamics, and psychological resilience among PLWH, who faced compounded vulnerabilities due to systemic inequities and the dual public health crises of HIV and COVID-19. Through semi-structured interviews with ten participants from diverse backgrounds, the study captured the profound impacts of disrupted healthcare systems, heightened stigma, and social isolation on this marginalized population. The findings reveal that the pandemic exacerbated existing inequities …


Developing Staff Training Modules To Enhance Neurodiversity-Affirming Care In An Inpatient Psychiatric Setting, Haley Morris 2025 Medical University of South Carolina

Developing Staff Training Modules To Enhance Neurodiversity-Affirming Care In An Inpatient Psychiatric Setting, Haley Morris

Entry-Level Occupational Therapy Doctorate - Doctoral Capstone Symposium

Introduction: Individuals with autism spectrum disorder (ASD) are admitted to psychiatric hospitals at higher rates and for longer durations compared to neurotypical individuals (Kuriakose et al., 2018). Externalizing behaviors, such as aggression and self-injury, significantly increase hospitalization risk, yet standard psychiatric interventions (e.g., traditional process groups) are often ineffective for this population. A key barrier is the lack of ASD-specific training among hospital staff (Siegel & Gabriels, 2012). This capstone project aimed to address this gap by developing and implementing an educational training program to improve patient-centered, neurodiversity-affirming care across all inpatient psychiatric units. The primary aims were to: …


Understanding The Experience Of Survivorship: Self-Efficacy, Emotional Wellbeing, And Post-Traumatic Growth Across A 6-Month Period In Women Diagnosed With Breast Cancer, Shannon N. Hiscock 2025 West Chester University

Understanding The Experience Of Survivorship: Self-Efficacy, Emotional Wellbeing, And Post-Traumatic Growth Across A 6-Month Period In Women Diagnosed With Breast Cancer, Shannon N. Hiscock

West Chester University Doctoral Projects

Breast cancer is one of the most common cancers in the world. Diagnosis and treatment can be traumatic, leading to declining physical and psychological health, but also a process of psychological evolution known as post-traumatic growth (PTG). Self-efficacy is a factor that is associated with positive outcomes in breast cancer, including emotional well-being and post-traumatic growth. The purpose of this study was to examine changes across 6-months in biopsychosocial variables (self-efficacy, PTG, and emotional well-being), as well as the relationships between these variables, in an effort to identify areas for intervention early in breast cancer treatment to promote positive mental …


Distinguishing Narcolepsy Hallucinations From Drug-Induced Hallucinations In An Adolescent With Comorbidities, Avidor Gerstenfeld, Biwy Emmanuella Cadet, Salma Alkhatib, Annette Santiago 2025 HCA Healthcare

Distinguishing Narcolepsy Hallucinations From Drug-Induced Hallucinations In An Adolescent With Comorbidities, Avidor Gerstenfeld, Biwy Emmanuella Cadet, Salma Alkhatib, Annette Santiago

East Florida Division GME Research Day 2025

No abstract provided.


Comparing Efficacy Of Psychotropic Classes To Control Aggression Among Pediatric Patients Hospitalized With Oppositional Defiant Disorder, Orestes Hadjistamoulou, Sindhura Kompella, Melissa Ricardo, Samuel Neuhut 2025 HCA Healthcare

Comparing Efficacy Of Psychotropic Classes To Control Aggression Among Pediatric Patients Hospitalized With Oppositional Defiant Disorder, Orestes Hadjistamoulou, Sindhura Kompella, Melissa Ricardo, Samuel Neuhut

East Florida Division GME Research Day 2025

No abstract provided.


Groundbreaking Insights On Trauma And Justice: A Review Of Sexual Violence, Dissociation, And Inequality: A Guide To Understanding Traumatic Memory By Muriel Salmona, Kate Rose 2025 Northern Arizona University

Groundbreaking Insights On Trauma And Justice: A Review Of Sexual Violence, Dissociation, And Inequality: A Guide To Understanding Traumatic Memory By Muriel Salmona, Kate Rose

Dignity: A Journal of Analysis of Exploitation and Violence

No abstract provided.


Lifetime History Of Concussions In Relation To Blind Perceptual Distance Estimation Ability, MacKenzie K. Miller 2025 University of Central Florida

Lifetime History Of Concussions In Relation To Blind Perceptual Distance Estimation Ability, Mackenzie K. Miller

Honors Undergraduate Theses

This study examined the relationship between visuospatial estimation and a lifetime history of concussions. Current literature on concussions investigates visuospatial working memory and estimation ability separately, but not conjointly. In order to examine this relationship, a novel neuropsychological task was designed to measure visuospatial estimation ability in working memory, named the Perceptual Estimation Test (PET). This novel task was designed with three variations that would increase in complexity as they progressed, and each variation would include three trials. Participants were scored on their accuracy performance during the PET. Participants aged 18-25 were recruited from students attending the University of Central …


A Framework For Trauma-Informed Mediation: A Heart And Mind Approach To Conflict Resolution, Michael Saini, Raheena Lalani Dahya, Shely Polak 2025 University of Toronto Faculty of Law

A Framework For Trauma-Informed Mediation: A Heart And Mind Approach To Conflict Resolution, Michael Saini, Raheena Lalani Dahya, Shely Polak

Cardozo Journal of Conflict Resolution

Unresolved trauma histories can have both short and long-term consequences on children and parents' overall functioning. Using a trauma-informed approach to mediation, we first briefly highlight the impactofadversechildhood experiencesandunresolvedtraumasonadults. We then consider the various vulnerabilities and activations presented within mediation and the fundamental principles of trauma-informed mediation to assist parties in remaining within the "window of tolerance" during the mediation. Trauma-informed mediation is an approach that encourages mediators to be aware of potential trauma activations and to engage in compassionate practices to allow parties to engage within their own individualized "window of tolerance" to resolve disputes. We explore the unique …


Investigating Protective And Risk Factors And Predictive Insights For Aboriginal Perinatal Mental Health: Explainable Artificial Intelligence Approach, Guanjin Wang, Hachem Bennamoun, Wai Hang Kwok, Jenny Paola Ortega Quimbayo, Bridgette Kelly, Trish Ratajczak, Rhonda Marriott, Roz Walker, Jayne Kotz 2025 Edith Cowan University

Investigating Protective And Risk Factors And Predictive Insights For Aboriginal Perinatal Mental Health: Explainable Artificial Intelligence Approach, Guanjin Wang, Hachem Bennamoun, Wai Hang Kwok, Jenny Paola Ortega Quimbayo, Bridgette Kelly, Trish Ratajczak, Rhonda Marriott, Roz Walker, Jayne Kotz

Research outputs 2022 to 2026

Background: Perinatal depression and anxiety significantly impact maternal and infant health, potentially leading to severe outcomes like preterm birth and suicide. Aboriginal women, despite their resilience, face elevated risks due to the long-term effects of colonization and cultural disruption. The Baby Coming You Ready (BCYR) model of care, centered on a digitized, holistic, strengths-based assessment, was co-designed to address these challenges. The successful BCYR pilot demonstrated its ability to replace traditional risk-based screens. However, some health professionals still overrely on psychological risk scores, often overlooking the contextual circumstances of Aboriginal mothers, their cultural strengths, and mitigating protective factors. This highlights …


Psychotropic Polypharmacy In Dementia: A Retrospective Analysis For People With Neuropsychiatric Symptoms Referred To An Australian Dementia Support Service, Mustafa Atee, Andrew Stafford, Daniel Whiting, Ya Ping Lee, Christopher Morrow, Guillaume Nyakaboyi, Ella Warnes, Thomas Morris 2025 Edith Cowan University

Psychotropic Polypharmacy In Dementia: A Retrospective Analysis For People With Neuropsychiatric Symptoms Referred To An Australian Dementia Support Service, Mustafa Atee, Andrew Stafford, Daniel Whiting, Ya Ping Lee, Christopher Morrow, Guillaume Nyakaboyi, Ella Warnes, Thomas Morris

Research outputs 2022 to 2026

Background and Objectives: Despite their limited benefits and serious adverse effects, psychotropics remain frequently prescribed for neuropsychiatric symptoms (NPS) of dementia. Psychotropic polypharmacy, the use of two or more concomitant psychotropic medications, is therefore not recommended for people with dementia. The objectives of this study were to investigate the prevalence of psychotropic polypharmacy in Australians living with dementia whose caregivers sought external NPS support from Dementia Support Australia (DSA; the national provider of NPS support) and the association of psychotropic polypharmacy with their demographics and NPS characteristics. Methods: A retrospective cross-sectional study of a subset of DSA referrals at baseline …


The Physiological Consequences Of And Recovery Following The Australian Special Forces Selection Course, Angela C. Uphill, Kristina L. Kendall, Bradley A. Baker, Stuart N. Guppy, Hannah M. Brown, Michael Vacher, Bradley C. Nindl, G. Gregory Haff 2025 Edith Cowan University

The Physiological Consequences Of And Recovery Following The Australian Special Forces Selection Course, Angela C. Uphill, Kristina L. Kendall, Bradley A. Baker, Stuart N. Guppy, Hannah M. Brown, Michael Vacher, Bradley C. Nindl, G. Gregory Haff

Research outputs 2022 to 2026

This study aimed to determine the energy requirements, physiological consequences, and recovery rate from the Australian Special Forces Selection Course. Ninety-three male soldiers (mean ± SD, 28.1 ± 3.6 years, 1.81 ± 0.1 m, 85.1 ± 8.1 kg) vol-unteered for this study. Body composition via dual-energy X-ray absorptiometry, hormones and resting metabolic rate were assessed before, immediately after, and at 1, 3, 5, and 8 weeks post-course. Energy expenditure, assessed via doubly-labelled water during the first 10 days of the course significantly exceeded energy intake (expenditure: 7680 ± 1095 kcal. day–1, in-take: 3859 ± 704 kcal. day– 1). Body mass …


Sleep Discrepancy And Cognitive Function In Community-Dwelling Older Adults, Nadia Soh, Stephanie R. Rainey-Smith, James D. Doecke, Rodrigo Canovas, Romola S. Bucks, Melissa Ree, Michael Weinborn 2025 Edith Cowan University

Sleep Discrepancy And Cognitive Function In Community-Dwelling Older Adults, Nadia Soh, Stephanie R. Rainey-Smith, James D. Doecke, Rodrigo Canovas, Romola S. Bucks, Melissa Ree, Michael Weinborn

Research outputs 2022 to 2026

This was the first study to use cluster analysis to characterise sleep discrepancy (the discordance between self-reported and objective sleep) across multiple sleep parameters, in community-dwelling older adults. For sleep efficiency, negative discrepancy (the tendency to self-report worse sleep than objectively-measured) was associated with poorer memory, independent of insomnia severity, depressive symptoms and objective sleep. This suggests a unique role for sleep discrepancy as a possible risk factor for future cognitive decline, and warrants the need for further research.


Finding Love On The Spectrum: An Analysis Of Social And Romantic Relationships Of Autistic College Students, Kaylee Spinner 2025 Eastern Illinois University

Finding Love On The Spectrum: An Analysis Of Social And Romantic Relationships Of Autistic College Students, Kaylee Spinner

Masters Theses

Autism Spectrum Disorder (ASD) is characterized by difficulties in socialization, communication, and developing relationships with others. While many autistic individuals desire to start relationships with others, many do not have a very strong understanding of the use of nonverbal communication or how to develop these connections organically. As autistic individuals have become more open about wanting these resources to form social and romantic relationships, there has been more of a push in the literature to include social skills training for forming social relationships. However, the research on the desire for or development of romantic relationships for autistic individuals is still …


Video Games In The Management Of Adhd: A Novel Approach To Adjunct Traditional Treatment, Lekhya Kintada, France Leandre 2025 HCA Healthcare

Video Games In The Management Of Adhd: A Novel Approach To Adjunct Traditional Treatment, Lekhya Kintada, France Leandre

North Florida Division GME Research Day 2025

No abstract provided.


Cocaine Induced Agranulocytosis And Neutropenia, Maria Gomez Alvarez, Ashish Govan, Raymond LaRocque 2025 HCA Healthcare

Cocaine Induced Agranulocytosis And Neutropenia, Maria Gomez Alvarez, Ashish Govan, Raymond Larocque

East Florida Division GME Research Day 2025

Introduction: Cocaine use in the United states is seen in many cases within the hospital system. Typically, they present with tachycardia, hypertension, sweating, even heart attack. Due to the uncontrolled sale and distribution of drugs, patients can be exposed to other additives in drugs which can lead to unexpected complications. Cocaine laced with levamisole (an antiparasitic drug used in veterinary medicine) can lead to agranulocytosis and neutropenia. Cocaine being the second most used illegal drug following marijuana it may be much more common than we think. Millions of individuals use cocaine yearly and develop a heavy addiction with use of …


Emerging Role Of Liafensine In The Treatment Of Treatment Resistant Depression: Insights From The Enlighten Trial, Karla Narvaez, Saad Masud, Richard Callahan 2025 HCA Healthcare

Emerging Role Of Liafensine In The Treatment Of Treatment Resistant Depression: Insights From The Enlighten Trial, Karla Narvaez, Saad Masud, Richard Callahan

East Florida Division GME Research Day 2025

Background: Treatment-resistant depression (TRD) remains a significant unmet need, affecting about one third of patients with major depressive disorder who fail to respond to two or more antidepressant trials. There is a need for new pharmacological approaches. Liafensine (also known as DB104) is a first-in-class triple reuptake inhibitor targeting serotonin, norepinephrine, and dopamine transporters, whose development has recently incorporated a precision medicine approach. Mechanism of Action: Liafensine inhibits reuptake of all three major monoamines (serotonin, norepinephrine, and dopamine) distinguishing it from existing SSRIs, SNRIs, or other agents which typically target one or two systems. A genetic biomarker, ANK3 (also called …


Ministry Organization Response To The Mental Health Crisis, Bryn L. Wood 2025 Liberty University

Ministry Organization Response To The Mental Health Crisis, Bryn L. Wood

Senior Honors Theses

The mental health crisis has been negatively affecting individuals across the globe for about half a century, only growing in its impact each year. However, following the Covid-19 pandemic, mental health crises skyrocketed. This is especially true for youth and young adults as physical isolation has altered many facets of their lives. This thesis will explore the mental health crisis, as well as the way it has impacted youth and young adult organizations. Specifically, it will discuss research on recommended ways for these organizations to respond to the mental health crisis through unique programming and how these practices have been …


Postpartum Depression In Adolescent Mothers: Evaluating The Effectiveness Of Screening Tools, Social And Cultural Interventions, Ysabella M. Co 2025 Dominican University of California

Postpartum Depression In Adolescent Mothers: Evaluating The Effectiveness Of Screening Tools, Social And Cultural Interventions, Ysabella M. Co

Nursing | Senior Theses

Background: Pregnancies among adolescents is often an outcome of improper sex education and understanding. It is vital to provide mothers with the proper medical care and resources throughout their pregnancy and postpartum period to prevent any risks or harm from occurring. With the complexities and stressors of pregnancy at such a young age, it is important for healthcare to provide resources regarding postnatal depression diagnoses and interventions, especially to a population that is at risk for mental health issues. Objective: To provide adolescent mothers thorough medical care and lessen the risk of experiencing postpartum depression. By providing frequent …


The Critical Role Of External Involvement In Supporting Adolescent Mothers Facing Postpartum Depression, Samantha Campopiano 2025 Dominican University of California

The Critical Role Of External Involvement In Supporting Adolescent Mothers Facing Postpartum Depression, Samantha Campopiano

Nursing | Senior Theses

Postpartum depression (PPD) is a significant mental health concern for adolescent mothers, especially those without a reliable support system. The current research demonstrates the importance of a support system, effective interventions, and prevention strategies for easier navigation of postpartum depression. Some effective interventions researched were therapy groups, personalized home visits, and using social media platforms to deliver therapy. This research proposal aims to examine the effectiveness of a nurse-led educational intervention for postpartum adolescent mothers without support. A quasi-experimental design will be used, with pre-and post-test assessments using the Edinburgh Postnatal Depression Scale (EPDS) to measure PPD symptoms in 100 …


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