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Second Messenger/Signal Transduction Pathways In Major Mood Disorders: Moving From Membrane To Mechanism Of Action, Part Ii: Bipolar Disorder, Mark Niciu, Dawn F. Ionescu, Daniel C. Matthews, Erica M. Richards, Carlos A. Zarate 2013 National Institutes of Health, Bethesda, MD

Second Messenger/Signal Transduction Pathways In Major Mood Disorders: Moving From Membrane To Mechanism Of Action, Part Ii: Bipolar Disorder, Mark Niciu, Dawn F. Ionescu, Daniel C. Matthews, Erica M. Richards, Carlos A. Zarate

Psychiatry and Behavioral Sciences Faculty Publications

The etiopathogenesis and treatment of major mood disorders have historically focused on modulation of monoaminergic (serotonin, norepinephrine, dopamine) and amino acid [γ-aminobutyric acid (GABA), glutamate] receptors at the plasma membrane. Although the activation and inhibition of these receptors acutely alter local neurotransmitter levels, their neuropsychiatric effects are not immediately observed. This time lag implicates intracellular neuroplasticity as primary in the mechanism of action of antidepressants and mood stabilizers. The modulation of intracellular second messenger/signal transduction cascades affects neurotrophic pathways that are both necessary and sufficient for monoaminergic and amino acid–based treatments. In this review, we will discuss the evidence in …


Effects Of Perceived Support From Mothers, Fathers, And Teachers On Depressive Symptoms During The Transition To Middle School, Sandra Rueger, Pan Chen, Lyndsay Jenkins 2013 University of Chicago

Effects Of Perceived Support From Mothers, Fathers, And Teachers On Depressive Symptoms During The Transition To Middle School, Sandra Rueger, Pan Chen, Lyndsay Jenkins

Faculty Research and Creative Activity

No abstract provided.


Combined Erp/Fmri Evidence For Early Word Recognition Effects In The Posterior Inferior Temporal Gyrus, Joseph Dien, Eric S. Brian, Dennis L. Molfese, Brian T. Gold 2013 University of Maryland at College Park

Combined Erp/Fmri Evidence For Early Word Recognition Effects In The Posterior Inferior Temporal Gyrus, Joseph Dien, Eric S. Brian, Dennis L. Molfese, Brian T. Gold

Center for Brain, Biology, and Behavior: Faculty Publications

Two brain regions with established roles in reading are the posterior middle temporal gyrus and the posterior fusiform gyrus. Lesion studies have also suggested that the region located between them, the posterior inferior temporal gyrus (pITG), plays a central role in word recognition. However, these lesion results could reflect disconnection effects since neuroimaging studies have not reported consistent lexicality effects in pITG. Here we tested whether these reported pITG lesion effects are due to disconnection effects or not using parallel ERP/fMRI studies. We predicted that the Recognition Potential (RP), a left-lateralized ERP negativity that peaks at about 200–250 ms, might …


Transient Measurement Error In A Diverse Population, Sean Potter 2013 Southern Methodist University

Transient Measurement Error In A Diverse Population, Sean Potter

Collection of Engaged Learning

The assessment of personality has important implications for clinicians, personality researchers, and the workplace setting. The accurate assessment of personality is therefore crucial to these various fields. However, measurement error has not had the necessary attention it deserves. In particular, the effect of transient measurement error on personality assessment has only begun to be recently studied. Furthermore, only undergraduate samples of relatively homogenous studies have been examined. The purpose of this study was to examine the impact of transient error for personality assessment in an older, more diverse population. Participants completed a test-retest study across a time frame (1 week) …


Drug Firms, The Codification Of Diagnostic Categories, And Bias In Clinical Guidelines, Lisa Cosgrove, Emily E. Wheeler 2013 University of Massachusetts Boston

Drug Firms, The Codification Of Diagnostic Categories, And Bias In Clinical Guidelines, Lisa Cosgrove, Emily E. Wheeler

Counseling, School Psychology & Sport Faculty Publication Series

The profession of medicine is predicated upon an ethical mandate: first do no harm. However, critics charge that the medical profession’s culture and its public health mission are being undermined by the pharmaceutical industry’s wide-ranging influence. In this article, we analyze how drug firms influence psychiatric taxonomy and treatment guidelines such that these resources may serve commercial rather than public health interests. Moving beyond a conflict-of-interest model, we use the conceptual and normative framework of institutional corruption to examine how organized psychiatry’s dependence on drug firms has distorted science. We suggest that academic-industry relationships have led to the corruption of …


Patient Perceptions Of Physicians And Medication Adherence Among Medicare Part D Beneficiaries, Lori Marquinne Ward 2013 Purdue University

Patient Perceptions Of Physicians And Medication Adherence Among Medicare Part D Beneficiaries, Lori Marquinne Ward

Open Access Dissertations

Ward, Lori Marquinne. Ph.D., Purdue University, December, 2013. Patient Perceptions of Physicians and Medication Adherence Among Medicare Part D Beneficiaries. Major Professor: Joseph Thomas III.

An observational database analysis using Medicare Current Beneficiary Survey data was conducted to examine patient perceptions of physicians and associations with adherence to antihypertensive medication among Medicare beneficiaries enrolled in Medicare Part D. The study sample included beneficiaries if they were 65 years or older, dwelling in the community, had a diagnosis of hypertension in 2007, were enrolled in Medicare Part D all 12 months in 2008, and had Medicare Part D claims for antihypertensive …


The Flexible Fairness: Equality, Earned Entitlement, And Self-Interest, Chunliang Feng, Yi Luo, Ruolei Gu, Lucas S. Broster, Xueyi Shen, Tengxiang Tian, Yue-Jia Luo, Frank Krueger 2013 Beijing Normal University, China

The Flexible Fairness: Equality, Earned Entitlement, And Self-Interest, Chunliang Feng, Yi Luo, Ruolei Gu, Lucas S. Broster, Xueyi Shen, Tengxiang Tian, Yue-Jia Luo, Frank Krueger

Behavioral Science Faculty Publications

The current study explored whether earned entitlement modulated the perception of fairness in three experiments. A preliminary resource earning task was added before players decided how to allocate the resource they jointly earned. Participants' decision in allocation, their responses to equal or unequal offers, whether advantageous or disadvantageous, and subjective ratings of fairness were all assessed in the current study. Behavioral results revealed that participants proposed more generous offers and showed enhanced tolerance to disadvantageous unequal offers from others when they performed worse than their presumed "partners," while the reverse was true in the better-performance condition. The subjective ratings also …


Effects Of Anger Awareness And Expression Training Versus Relaxation Training On Headaches: A Randomized Trial, Olga Slavin-Spenny, Mark A. Lumley, Elyse R. Thakur, Dana C. Nevedal, Alaa M Hijazi 2013 Wayne State University

Effects Of Anger Awareness And Expression Training Versus Relaxation Training On Headaches: A Randomized Trial, Olga Slavin-Spenny, Mark A. Lumley, Elyse R. Thakur, Dana C. Nevedal, Alaa M Hijazi

Psychology Faculty Research Publications

Background and purpose: Stress contributes to headaches, and effective interventions for headaches routinely include relaxation training (RT) to directly reduce negative emotions and arousal. Yet, suppressing negative emotions, particularly anger, appears to augment pain, and experimental studies suggest that expressing anger may reduce pain. Therefore, we developed and tested anger awareness and expression training (AAET) on people with headaches.

Methods: Young adults with headaches (N = 147) were randomized to AAET, RT, or a wait-list control. We assessed affect during sessions, and process and outcome variables at baseline and 4 weeks after treatment.

Results: On process measures, …


Factors And Convergent Validity Of The Pet Attachment And Life Impact Scale (Pals), Lisa DeMarni Cromer, M. Rose Barlow 2013 University of Tulsa

Factors And Convergent Validity Of The Pet Attachment And Life Impact Scale (Pals), Lisa Demarni Cromer, M. Rose Barlow

Psychological Sciences Faculty Publications and Presentations

Human-animal interaction (HAI) provides benefits for humans. Emotional attachment to pets is a possible mechanism for benefits but there is no standard operationalization for “attachment to pets.” The study presented here (N = 651) uses a pet attachment measure based on qualitative research about benefits of pets. This measure, the Pet Attachment and Life Impact Scale (PALS), has four factors that measure Love, Regulation, Personal Growth, and Negative Impacts. We present exploratory factor analysis and confirmatory factor analysis of the instrument. We then examine convergent validity with four a priori derived measures of pet attachment (Anthropomorphism Scale, CENSHARE PAS, …


Parent Attributional Style And Early Termination From Child And Parent Therapy, Ryan James Mattek 2013 Marquette University

Parent Attributional Style And Early Termination From Child And Parent Therapy, Ryan James Mattek

Dissertations (1934 -)

ABSTRACT

PARENT ATTRIBUTIONAL STYLE AND EARLY TERMINATION

FROM CHILD AND PARENT THERAPY

Ryan J. Mattek, M.A.

Marquette University, 2013

Behavior problems are prevalent in young children and represent a threat to a child's typical development. These early behavior problems are even more common in children from low-income, urban settings. If left untreated, such challenging behaviors may become ingrained and lead to later more severe behaviors including aggression, violence, and anti-social behaviors. Research has demonstrated that participation in child and parent therapy (CPT) programs significantly reduces problematic child behaviors while increasing positive behaviors in both the child and the parent. However, …


Sensory-Specific Appetition: Postingestive Detection Of Glucose Rapidly Promotes Continued Consumption Of A Recently Encountered Flavor, Kevin P. Myers, Marisa S. Taddeo, Emily K. Richards 2013 Bucknell University

Sensory-Specific Appetition: Postingestive Detection Of Glucose Rapidly Promotes Continued Consumption Of A Recently Encountered Flavor, Kevin P. Myers, Marisa S. Taddeo, Emily K. Richards

Faculty Journal Articles

It is generally thought that macronutrients stimulate intake when sensed in the mouth (e.g., sweet taste) but as food enters the GI tract its effects become inhibitory, triggering satiation processes leading to meal termination. Here we report experiments extending recent work (see [1]) showing that under some circumstances nutrients sensed in the gut produce a positive feedback effect, immediately promoting continued intake. In one experiment, rats with intragastric (IG) catheters were accustomed to consuming novel flavors in saccharin daily while receiving water infused IG (5 ml/15 min). The very first time glucose (16% w/w) was infused IG instead of water, …


Supervisees' Experiences Of Ruptures In Multicultural Supervision: A Qualitative Study, Laura Lubbers 2013 Marquette University

Supervisees' Experiences Of Ruptures In Multicultural Supervision: A Qualitative Study, Laura Lubbers

Dissertations (1934 -)

As the paradigmatic shift of multiculturalism emerges in counseling, the constructs of culture and context warrant examination in the supervision process. With an understanding that conflict is inevitable in supervision relationships particularly when cultural topics are being discussed, investigation into the process of ruptures and rupture repair as they take place within multicultural supervision is warranted. Despite the attention paid to addressing culture in supervision, surprisingly little empirical attention has focused on supervisee experiences of ruptures in multicultural supervision. This study sought to provide a deeper understanding of supervisees' experiences of ruptures in multicultural supervision. Twelve participants were interviewed regarding …


Research Brief: "Prospectively Assessed Post-Traumatic Stress Disorder And Associated Physical Activity", Institute for Veterans and Military Families at Syracuse University 2013 Syracuse University

Research Brief: "Prospectively Assessed Post-Traumatic Stress Disorder And Associated Physical Activity", Institute For Veterans And Military Families At Syracuse University

Institute for Veterans and Military Families

This brief is about the connection between physical activity and symptoms of post-traumatic stress disorder in veterans. In policy and practice, service members who experienced combat should have high levels of physical activity in order to reduce the possibility of developing PTSD, clinicians should mention the importance of physical activity for mental health to service members, as well as recommend alternatives for veterans who are unable to do high levels of physical activity. The VA should implement and promote fitness programs for service members and veterans to lower the possibility of developing PTSD, and policymakers should fund physical activity programs …


Research Brief: "Predictors Of Psychiatric Disorders In Combat Veterans", Institute for Veterans and Military Families at Syracuse University 2013 Syracuse University

Research Brief: "Predictors Of Psychiatric Disorders In Combat Veterans", Institute For Veterans And Military Families At Syracuse University

Institute for Veterans and Military Families

This brief is about the predictors of mental health diagnoses within a sample of Marines who experienced combat in Iraq and Afghanistan. In policy and practice, support networks should be implemented for servicemembers to share with their peers, clinicians should give female servicemembers and others who have a higher likelihood of developing a mental health disorder after combat information on how to prevent certain psychiatric disorders, and families should know the signs of psychiatric disorders to help servicemembers in their re-adjustment period after deployment. Military branches and policymakers could improve counseling for servicemembers returning from combat and encourage servicemembers to …


Deficits In Retrospective And Prospective Components Underlying Prospective Memory Tasks In Amnestic Mild Cognitive Impairment, Ting Zhou, Lucas S. Broster, Yang Jiang, Feng Bao, Huali Wang, Juan Li 2013 Chinese Academy of Sciences, China

Deficits In Retrospective And Prospective Components Underlying Prospective Memory Tasks In Amnestic Mild Cognitive Impairment, Ting Zhou, Lucas S. Broster, Yang Jiang, Feng Bao, Huali Wang, Juan Li

Behavioral Science Faculty Publications

OBJECTIVES: By use of purer indices of PM and RM components than previous studies and adoption of three PM task types, the present study aimed to investigate the deficits of these two components underlying global impairment at a PM task in individuals with amnestic mild cognitive impairment (aMCI).

METHODS: Nineteen aMCI patients and 22 normal controls were examined on event-, time- and activity-based PM tasks. Separate scores were obtained for initiation of intentions (i.e. PM component) and for the content of the intentions (i.e. RM component).

RESULTS: Individuals with aMCI achieved lower PM component (but not RM component) scores than …


Adverse Childhood Experiences, Disability And Health-Risk Behaviors, Sophia Miryam Schussler-Fiorenza Rose MD, PhD 2013 Stanford University School of Medicine

Adverse Childhood Experiences, Disability And Health-Risk Behaviors, Sophia Miryam Schussler-Fiorenza Rose Md, Phd

Population Health Matters (Formerly Health Policy Newsletter)

No abstract provided.


Health Consequences Of Sexual Hookups For First-Year College Women: A One-Year Prospective Investigation, Robyn Leanne Fielder 2013 Syracuse University

Health Consequences Of Sexual Hookups For First-Year College Women: A One-Year Prospective Investigation, Robyn Leanne Fielder

Psychology - Dissertations

"Hookups" are sexual encounters between partners who are not in a traditional committed romantic relationship. The majority of college students engage in hookup behavior, but little is known about the health consequences of hookups. This longitudinal study examined the effects of sexual hookups on mental health and risk for sexual victimization (SV) and sexually transmitted diseases (STDs) among first-year college women. It was hypothesized that sexual hookup behavior would negatively affect women's mental health and increase their likelihood of experiencing SV and STDs. Participants (N = 483) completed 13 monthly online surveys that assessed sexual behavior (performing oral sex, receiving …


Interests In High-Functioning Autism Are More Intense, Interfering, And Idiosyncratic Than Those In Neurotypical Development, Laura G. Anthony, Lauren Kenworthy, Benjamin E. Yerys, Kathryn F. Jankowski, Joette James, Madeline B. Harms, Alex Martin, Gregory L. Wallace 2013 George Washington University

Interests In High-Functioning Autism Are More Intense, Interfering, And Idiosyncratic Than Those In Neurotypical Development, Laura G. Anthony, Lauren Kenworthy, Benjamin E. Yerys, Kathryn F. Jankowski, Joette James, Madeline B. Harms, Alex Martin, Gregory L. Wallace

Psychiatry and Behavioral Sciences Faculty Publications

Although circumscribed interests are pathognomonic with autism, much about these interests remains unknown. Using the Interests Scale (IS), this study compares interests between 76 neurotypical (NT) individuals and 109 individuals with high-functioning autism spectrum disorder (HF-ASD) matched groupwise on age, IQ, and gender ratio. Participants and their parents/caregivers completed diagnostic measures (the Autism Diagnostic Interview—Revised and the Autism Diagnostic Observation Schedule; HF-ASD only), cognitive tests (Wechsler IQ Scales), and questionnaires (the Repetitive Behavior Scale—Revised, the Behavior Rating Inventory of Executive Function, and the Social Responsiveness Scale), in addition to the IS. Consistent with previous research, HF-ASD and NT individuals did …


Controlled Attention And Sleep Deprivation: Adding A Self-Regulation Approach?, June J. Pilcher, Holly A. Geldhauser, J. Adam Beeco, Tracy A. Lindquist 2013 Clemson University

Controlled Attention And Sleep Deprivation: Adding A Self-Regulation Approach?, June J. Pilcher, Holly A. Geldhauser, J. Adam Beeco, Tracy A. Lindquist

Publications

The current study examined performance on an automated task battery under short-term sleep deprivation and non-sleep deprivation conditions. Twenty-six volunteers completed the sleep deprivation study. Twenty-three volunteers completed the non-sleep deprivation study. Performance was examined across five test sessions during 25 hours of acute sleep deprivation conditions and during two days of non-sleep deprivation conditions. ANOVAs examining changes in performance from baseline levels indicated that performance under sleep deprivation conditions resulted in a decrease in performance in some tasks and an increase in estimated blood alcohol concentration. Non-sleep deprivation resulted in stable or increasing performance and a decrease in estimated …


Sex Trafficking Of Minors In Kentucky, Jennifer Cole, Elizabeth Anderson 2013 University of Kentucky

Sex Trafficking Of Minors In Kentucky, Jennifer Cole, Elizabeth Anderson

Center on Trauma and Children Reports

From executive summary:

Findings presented in this report are from telephone surveys conducted from July 2012 through April 2013 with 323 professionals who worked in agencies that serve at-risk youth and/or crime victims across Kentucky. Respondents were from all geographic and demographic communities in Kentucky, with the highest number serving Bluegrass metropolitan communities including Louisville, Lexington, and Northern Kentucky.


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