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An Examination Of Social Connectedness On Ptsd And Freezing In A Student Military Population, Jessica Marie Ledwith 2020 University of North Florida

An Examination Of Social Connectedness On Ptsd And Freezing In A Student Military Population, Jessica Marie Ledwith

UNF Graduate Theses and Dissertations

This study investigates the impact of social connectedness (SC) and post-traumatic stress disorder (PTSD) in a military college population, and their relation to physiological measures such as body sway, heart rate (HR), and heat rate variability (HRV). According to previous research, people with PTSD are more likely to exhibit a freezing response to affective images. In the present study, we explore the potential freezing response for military personnel at the levels of PTSD symptom groups and social connectedness. We also investigate the possible buffering effect social connectedness has on the outcome of PTSD and freezing. There was a total of ...


The Impact Of Bone Marrow Transplantion On Patients With Psychiatric Diagnoses: Medication Adherence Assessment, Brittany Galop 2020 University of Kentucky

The Impact Of Bone Marrow Transplantion On Patients With Psychiatric Diagnoses: Medication Adherence Assessment, Brittany Galop

Theses and Dissertations--Pharmacy

Objectives: We investigated whether there is a measurable difference in medication utilization for psychiatric conditions before and after bone marrow transplantation (BMT). Previous studies have identified a potential association between psychiatric conditions and immune function. We hypothesized that medication utilization for psychiatric diagnoses would be impacted by BMT.

Methods: This study was a retrospective, quasi-experimental cohort design. De-identified data was compiled from the Truven database for patients ranging from January 2009 through December 2016. Two measurements of medication utilization, proportion of days covered (PDC) and medication possession ratio (MPR) were calculated for each included Medispan-defined class of medications before analyzing ...


Evaluating Interpersonal Problems In Anorexia Nervosa Through The Lens Of Polyvagal Theory, marika morelan 2020 Claremont Colleges

Evaluating Interpersonal Problems In Anorexia Nervosa Through The Lens Of Polyvagal Theory, Marika Morelan

CMC Senior Theses

Eating disorders are an increasingly prevalent issue, especially among young women. While they aren’t a new phenomenon, they are historically under-researched, and remain widely misunderstood. Without understanding the causes underlying these disorders or the mechanisms working to maintain them, treating them successfully has proved to be incredibly difficult. This is especially the case with Anorexia Nervosa. Out of the six eating disorders in the DSM-5, it has the lowest treatment success rate and an alarmingly high relapse rate. Treating the disorder through weight restoration and the extinction of compensatory behaviors alone does not fully resolve the disordered pathology; interpersonal ...


Impact Of A Multimodal Exercise Program On Tibial Bone Health In Adolescents With Development Coordination Disorder: An Examination Of Feasibility And Potential Efficacy, Jocelyn L. Tan, Aris Siafarikas, Timo Rantalainen, Nicolas H. Hart, Fleur McIntyre, Beth Hands, Paola Chivers 2020 Edith Cowan University

Impact Of A Multimodal Exercise Program On Tibial Bone Health In Adolescents With Development Coordination Disorder: An Examination Of Feasibility And Potential Efficacy, Jocelyn L. Tan, Aris Siafarikas, Timo Rantalainen, Nicolas H. Hart, Fleur Mcintyre, Beth Hands, Paola Chivers

ECU Publications Post 2013

© 2020, International Society of Musculoskeletal and Neuronal Interactions. All rights reserved. Objectives: Developmental coordination disorder (DCD) compromises bone health purportedly due to lower levels of physical activity. The potential of an exercise intervention to improve bone health parameters in adolescents with DCD has not previously been studied. This study thus aimed to determine the impact of a multimodal exercise intervention on bone health in this population at-risk of secondary osteoporosis. Methods: Twenty-eight adolescents (17 male, 11 female) aged between 12-17 years (Mage =14.1) with DCD participated in a twice weekly, 13-week generalised multimodal exercise intervention. Peripheral quantitative computed tomography ...


Association Of Genetic Risks With Autism Spectrum Disorder And Early Neurodevelopmental Delays Among Children Without Intellectual Disability, Nagahide Takahashi, Taeko Harada, Tomoko Nishimura, Akemi Okamura, Damee Choi, Toshiki Iwabuchi, Hitoshi Kuwabara, Shu Takagai, Yoko Nomura, Nori Takei, Kenji J. Tsuchiya 2020 Hamamatsu University School of Medicine

Association Of Genetic Risks With Autism Spectrum Disorder And Early Neurodevelopmental Delays Among Children Without Intellectual Disability, Nagahide Takahashi, Taeko Harada, Tomoko Nishimura, Akemi Okamura, Damee Choi, Toshiki Iwabuchi, Hitoshi Kuwabara, Shu Takagai, Yoko Nomura, Nori Takei, Kenji J. Tsuchiya

Publications and Research

IMPORTANCE Autism spectrum disorder (ASD) is highly heritable, and modest contributions of common genetic variants to ASD have been reported. However, the association of genetic risks derived from common risk variants with ASD traits in children from the general population is not clear, and the association of these genetic risks with neurodevelopment in infants has not been well understood.

OBJECTIVE To test whether a polygenic risk score (PRS) for ASD is associated with neurodevelopmental progress at age 18 months and ASD traits at age 6 years among children from the general population.

DESIGN, SETTING, AND PARTICIPANTS In this cohort study ...


Comparing Sensitivity To Change Using The 6-Item Versus The 17-Item Hamilton Depression Rating Scale In The Guided Randomized Controlled Trial, Boadie W. Dunlop, Sagar V. Parikh, Anthony J. Rothschild, Michael E. Thase, Charles DeBattista, Charles R. Conway, Brent P. Forester, Francis M. Mondimore, Richard C. Shelton, Matthew Macaluso, Jennifer Logan, Paul Traxler, James Li, Holly Johnson, John F. Greden 2019 Emory University

Comparing Sensitivity To Change Using The 6-Item Versus The 17-Item Hamilton Depression Rating Scale In The Guided Randomized Controlled Trial, Boadie W. Dunlop, Sagar V. Parikh, Anthony J. Rothschild, Michael E. Thase, Charles Debattista, Charles R. Conway, Brent P. Forester, Francis M. Mondimore, Richard C. Shelton, Matthew Macaluso, Jennifer Logan, Paul Traxler, James Li, Holly Johnson, John F. Greden

Open Access Publications by UMMS Authors

BACKGROUND: Previous research suggests that the 17-item Hamilton Depression Rating Scale (HAM-D17) is less sensitive in detecting differences between active treatment and placebo for major depressive disorder (MDD) than is the HAM-D6 scale, which focuses on six core depression symptoms. Whether HAM-D6 shows greater sensitivity when comparing two active MDD treatment arms is unknown.

METHODS: This post hoc analysis used data from the intent-to-treat (ITT) cohort (N = 1541) of the Genomics Used to Improve DEpression Decisions (GUIDED) trial, a rater- and patient-blinded randomized controlled trial. GUIDED compared combinatorial pharmacogenomics-guided care with treatment as usual (TAU) in patients with MDD. Percent ...


Effectiveness Of Integrative Medicine Group Visits In Chronic Pain And Depressive Symptoms: A Randomized Controlled Trial, Paula Gardiner, Man Luo, Salvatore D'Amico, Katherine Gergen-Barnett, Laura F. White, Robert Saper, Suzanne Mitchell, Jane M. Liebschutz 2019 University of Massachusetts Medical School

Effectiveness Of Integrative Medicine Group Visits In Chronic Pain And Depressive Symptoms: A Randomized Controlled Trial, Paula Gardiner, Man Luo, Salvatore D'Amico, Katherine Gergen-Barnett, Laura F. White, Robert Saper, Suzanne Mitchell, Jane M. Liebschutz

Open Access Publications by UMMS Authors

BACKGROUND: Current treatment options for chronic pain and depression are largely medication-based, which may cause adverse side effects. Integrative Medical Group Visits (IMGV) combines mindfulness techniques, evidence based integrative medicine, and medical group visits, and is a promising adjunct to medications, especially for diverse underserved patients who have limited access to non-pharmacological therapies.

OBJECTIVE: Determine the effectiveness of IMGV compared to a Primary Care Provider (PCP) visit in patients with chronic pain and depression.

DESIGN: 9-week single-blind randomized control trial with a 12-week maintenance phase (intervention-medical groups; control-primary care provider visit).

SETTING: Academic tertiary safety-net hospital and 2 affiliated federally-qualified ...


An Exploratory Study Of How Millennials Approach And Communicate Mental Health In The Workplace, Johanna I. Seitenbach 2019 CUNY Bernard M Baruch College

An Exploratory Study Of How Millennials Approach And Communicate Mental Health In The Workplace, Johanna I. Seitenbach

Student Theses

Depression is the leading cause of disability worldwide, affecting more than 300 million people. As more millennials take on leadership positions, it is important to understand how companies are currently addressing mental health in the workplace and compare this to how millennials approach the subject. The quantitative analysis completed through this study helped to determine what a mentally healthy workplace looks and feels like for millennials. Companies are increasingly investing in mental health initiatives for several reasons: to increase brand recognition, to improve company culture, to mitigate potential lawsuits, and to increase employee engagement and retention. This survey assessed how ...


Memantine: Can It Be Used To Treat Children With Autism Spectrum Disorder?, Austin Brown, Katherine Liu, Pul Lee, Rachel Muhlenkamp, Manoranjan D'Souza 2019 Ohio Northern University

Memantine: Can It Be Used To Treat Children With Autism Spectrum Disorder?, Austin Brown, Katherine Liu, Pul Lee, Rachel Muhlenkamp, Manoranjan D'Souza

Pharmacy and Wellness Review

Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impairment in social, behavior and communicative skills. The current therapy for ASD only targets the associated symptoms such as aggression, self-harming acts or temper tantrums but not the core symptoms of social dysfunction. The pathology of ASD is not fully understood. Interestingly, imaging studies in ASD patients have reported abnormal high levels of glutamate in certain brain regions that play an important role in social interaction and communication. Thus, it has been hypothesized that medications attenuating glutamate transmission may be used as treatment for some of the core symptoms of ...


Examining Emotion-Related Processes In Selective Mutism; Autonomic, Behavioral And Parental Factors, Rachel B. Tenenbaum 2019 Florida International University

Examining Emotion-Related Processes In Selective Mutism; Autonomic, Behavioral And Parental Factors, Rachel B. Tenenbaum

FIU Electronic Theses and Dissertations

Selective mutism (SM) is associated with considerable individual and family burdens, significant long-term functional impairment, and risk for later psychopathology. However, literature examining the phenomenology of SM has been scant, and it remains unclear which mechanisms are related to the development or maintenance of SM. Multiple theoretical perspectives have been proposed, and it appears that several pathways may be involved and interact to lead to the development of SM. Emotionrelated processes, such as negative emotion reactivity, disruptions in emotion regulation, and parental behavior and emotionality have been proposed to be involved in the etiology and/or maintenance of SM. The ...


The Use Of Propranolol In The Treatment Of Posttraumatic Stress Disorder, Tana M. Peterman, Alison L. Huet, Sarah E. Drake, Jamie L. Drees, Robert D. Raiff, B. Shane Martin 2019 Ohio Northern University

The Use Of Propranolol In The Treatment Of Posttraumatic Stress Disorder, Tana M. Peterman, Alison L. Huet, Sarah E. Drake, Jamie L. Drees, Robert D. Raiff, B. Shane Martin

Pharmacy and Wellness Review

This article examines the rising issue of post-traumatic stress disorder (PTSD) and possible treatment options. PTSD is a behavioral disorder resulting from memory formation and association with a traumatic event. A search of the published literature reveals several positive studies and case reports suggesting that propranolol, a beta adrenergic receptor antagonist, may be useful for both treatment and prevention of PTSD. Additionally, current studies are being completed in different population groups to determine the overall effectiveness and mechanism by which propranolol is able to provide relief from certain symptoms common to the disorder. This article discusses the medical evidence and ...


Role Of The Pharmacist In Improving Treatment For Children With Concurrent Gastrointestinal And Autism Spectrum Disorders, Whitney R. Henry, Kaitlin A. Sanders, Jenna L. Schaffner, Leslie M. Hart, Whitney N. Detillion, Anne F. Gentry 2019 Ohio Northern University

Role Of The Pharmacist In Improving Treatment For Children With Concurrent Gastrointestinal And Autism Spectrum Disorders, Whitney R. Henry, Kaitlin A. Sanders, Jenna L. Schaffner, Leslie M. Hart, Whitney N. Detillion, Anne F. Gentry

Pharmacy and Wellness Review

Over the last several years, a noteworthy association between gastrointestinal (GI) disorders and autism spectrum disorders (ASD) has been documented, although no large population-based studies exist. GI disorders in ASD children may stem from the underlying behavioral, communication, sensory or neurological issues intrinsic to the autistic disorder itself; therefore, the incorporation of alternative therapies, including behavioral modification, may be compelling treatment additions to the GI care traditionally recommended in children. To improve GI symptoms and quality of life in ASD children, a multidisciplinary approach is optimal, with pharmacists playing an active role in determining appropriate pharmacotherapy. Although there is a ...


The Healing Power Of The Arts - Drama Therapy And The Use Of Theatre In The Treatment Of Trauma, Brooklyn Snyder 2019 Chapman University

The Healing Power Of The Arts - Drama Therapy And The Use Of Theatre In The Treatment Of Trauma, Brooklyn Snyder

Student Scholar Symposium Abstracts and Posters

Theatre is an incredibly valuable therapeutic tool. In this thesis, I explore the ways in which trauma can reshape individuals lives, both cognitively and physically, impeding their sense of self, ability to trust, engagement, and many other seemingly ordinary aspects of day to day life that those of us unaffected by trauma take for granted. Additionally, I cover how employing theatrical tools, like improvisation and role play, can act as a beneficial treatment option for those who have suffered a traumatic past. Drama therapy allows individuals to reconnect with their bodies and their minds, gain new perspectives on their experiences ...


Ontrack: A Program Evaluation, Justin Mynatt 2019 Lincoln Memorial University

Ontrack: A Program Evaluation, Justin Mynatt

Doctoral Projects

OnTrack is a program that provides coordinated specialty care (CSC) services for patients who have experienced their first episode of psychosis (FEP). Appropriately identifying and aggressively treating this vulnerable population, while providing support to both them and their families is critical for improved outcomes. Appropriate treatment of FEP patients can improve their quality of life, preserve brain matter, improve overall functioning, and lessen the burden of the clients’ family who may be involved in their care, such as caregiver strain or financial hardship. The purpose of this project is to evaluate the success of OnTrack, a FEP program, at improving ...


Effects Of Exercise For Depression, Rebecca Gleason 2019 Oral Roberts University

Effects Of Exercise For Depression, Rebecca Gleason

Health, Leisure, and Sport Sciences Undergraduate Work

The purpose of this study was to examine the effects of exercise for adolescents, middle-aged adults, and older adults with depression.

Literature from thirty-four professional medical journals and eight professional websites were reviewed. The resulting information was organized into categories as described in the purpose of the study.

In 2017, it was estimated that 17.3 million adults living in the United States had at least one major depressive episode, which came to be 7.1% of all adults (DBSA, 2019). In a 2019 review, causes of depression were related to personal factors, some being personality, drug or alcohol use ...


Improving Access To Mental Health Care With Nurse Practitioners, Jessica Whelan 2019 University of Missouri-St. Louis

Improving Access To Mental Health Care With Nurse Practitioners, Jessica Whelan

Dissertations

Problem: Over 40% of those with mental illness are untreated since the supply of psychiatrists does not meet the demand. The psychiatric mental health nurse practitioner (PMHNP) may be an adjunct in providing those services. The purpose of this quality assurance study was to evaluate outcomes of care between a PMHNP and a psychiatrist (medical doctor [MD]).

Methods: An observational, descriptive design with a retrospective medical record review of adult patients over a six-month period in a suburban, Midwestern, privately owned psychiatric practice.

Results: A total of 787 individual patients encountered at least one visit (N=787) although 3,679 ...


In Vivo Clonal Expansion And Phenotypes Of Hypocretin-Specific Cd4(+) T Cells In Narcolepsy Patients And Controls, Wei Jiang, James R. Birtley, Grant C. Weaver, Liying Lu, Lawrence J. Stern, Elizabeth D. Mellins 2019 Stanford University

In Vivo Clonal Expansion And Phenotypes Of Hypocretin-Specific Cd4(+) T Cells In Narcolepsy Patients And Controls, Wei Jiang, James R. Birtley, Grant C. Weaver, Liying Lu, Lawrence J. Stern, Elizabeth D. Mellins

Open Access Publications by UMMS Authors

Individuals with narcolepsy suffer from abnormal sleep patterns due to loss of neurons that uniquely supply hypocretin (HCRT). Previous studies found associations of narcolepsy with the human leukocyte antigen (HLA)-DQ6 allele and T-cell receptor alpha (TRA) J24 gene segment and also suggested that in vitro-stimulated T cells can target HCRT. Here, we present evidence of in vivo expansion of DQ6-HCRT tetramer(+)/TRAJ24(+)/CD4(+) T cells in DQ6(+) individuals with and without narcolepsy. We identify related TRAJ24(+) TCRalphabeta clonotypes encoded by identical alpha/beta gene regions from two patients and two controls. TRAJ24-G allele(+) clonotypes only expand in the two ...


Losing Our Minds To Madness: Paradigm Changes In Western European Perceptions Of Mental Illness, James Michael Cecil 2019 California Polytechnic State University, San Luis Obispo

Losing Our Minds To Madness: Paradigm Changes In Western European Perceptions Of Mental Illness, James Michael Cecil

History

Academia and scholarship of the 20th-century bred a renewed interest in mental illness throughout history. Despite an increase in the literature within the discourse surrounding "madness," scholars have generally failed to understand how and why Western European societies have viewed mental illness in various ways throughout recorded history. This paper argues that there remains an inherent, human desire to reject anything different from humanity, particularly mental illness, which is nearly impossible to fully comprehend. This is especially true in the case of how societies have institutionalized, punished, and subjugated the "mad" individual.


Dimensions Of Symptom Presentation And Scholarly Representation Of Young Females With Fragile X Syndrome, Andrew N. Snell 2019 Brigham Young University

Dimensions Of Symptom Presentation And Scholarly Representation Of Young Females With Fragile X Syndrome, Andrew N. Snell

Intuition: The BYU Undergraduate Journal of Psychology

No abstract provided.


Thinking Outside The Checkbox: Examining The Benefits Of Depression In The Workplace, Tyler L. Jensen 2019 Brigham Young University

Thinking Outside The Checkbox: Examining The Benefits Of Depression In The Workplace, Tyler L. Jensen

Intuition: The BYU Undergraduate Journal of Psychology

No abstract provided.


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