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Downregulation Of Mmp1 Expression Mediates The Anti-Aging Activity Of Citrus Sinensis Peel Extract Nanoformulation In Uv Induced Photoaging In Mice, Maha Salama, October University for Modern Sciences & Arts, The British University in Egypt 2021 The British University in Egypt

Downregulation Of Mmp1 Expression Mediates The Anti-Aging Activity Of Citrus Sinensis Peel Extract Nanoformulation In Uv Induced Photoaging In Mice, Maha Salama, October University For Modern Sciences & Arts, The British University In Egypt

Pharmacy

Aging of the skin is a complicated bioprocess that is affected by constant exposure to ultraviolet irradiation. The application of herbal-based anti-aging creams is still the best choice for treatment. In the present study, Citrus sinensis L. fruit peels ethanolic extract (CSPE) was formulated into lipid nanoparticles (LNPs) anti-aging cream. Eight different formulations of CSEP-LNPs were prepared and optimized using 23 full factorial designs. In vivo antiaging effect of the best formula was tested in Swiss albino mice where photo-aging was induced by exposure to UV radiation. HPLC-QToF-MS/MS metabolic profiling of CSPE led to the identification of twenty-nine metabolites. CSPE …


Nurse Practitioner Knowledge, Attitudes, And Likelihood Of Cbd Use In Clinical Practice, Kenita Murray, Deborah C. Gray 2021 Old Dominion University

Nurse Practitioner Knowledge, Attitudes, And Likelihood Of Cbd Use In Clinical Practice, Kenita Murray, Deborah C. Gray

College of Health Sciences Posters

Problem: Many Americans have begun to seek alternative and natural remedies for common medical conditions previously treated by prescription drugs. As highly trained clinical professionals, nurse practitioners (NP) are responsible for adequately educating patients about their clinical disease process and treatment options. Due to limited clinical research surrounding CBD, NPs may lack the proper qualifications and resources to counsel patients on CBD use adequately. Despite an increase in CBD curiosity and use among the American population, there are no studies that assess Nurse Practitioner (NP) provider's knowledge and attitudes towards CBD or the factors affecting NP's decisions for its use. …


The Influence Of Prenatal Yoga On Mental Health In Pregnancy During The Covid-19 Pandemic, Cathryn Duchette 2021 Western Kentucky University

The Influence Of Prenatal Yoga On Mental Health In Pregnancy During The Covid-19 Pandemic, Cathryn Duchette

Masters Theses & Specialist Projects

The COVID-19 pandemic poses risks to the mental health of expecting mothers as studies have demonstrated increased levels of stress and anxiety for new and expectant mothers during the pandemic. Prenatal yoga has been shown to be effective for improving mental health during pregnancy, but no research has been done to determine its effect on mental health during a pandemic. The purpose of this study was to determine the influence of a 10-week prenatal yoga intervention on the mental health of pregnant women during the COVID-19 pandemic. Baseline levels of anxiety and depression were high, with an average depression score …


Ketogenic Diet As A Preventative Measure Or Treatment Option For Osteoarthritistargeting Nfl Athletes As A High-Risk Group, Kelsi J. Smith 2021 Southeastern University - Lakeland

Ketogenic Diet As A Preventative Measure Or Treatment Option For Osteoarthritistargeting Nfl Athletes As A High-Risk Group, Kelsi J. Smith

Selected Honors Theses

Osteoarthritis (OA) is a prevalent joint disease that results from the degradation of articular cartilage, leading to inflammation, pain, and eventual joint failure. At one time, it was thought that OA was only the result of the natural decline experienced in old age; however, various risk factors have now been identified that may contribute to an increased risk for developing OA. Risk factors may include joint loading, altered biomechanics, obesity, and joint injury, to which athletes are exposed at a high rate. NFL athletes are one group of athletes that have continued to show a high prevalence of arthritis in …


A British Health Seeker In Southern California: Beatrice Harraden (1864-1936), Molly McClain 2021 University of San Diego

A British Health Seeker In Southern California: Beatrice Harraden (1864-1936), Molly Mcclain

History: Faculty Scholarship

In the late nineteenth-century, health tourists travelled the globe in search of relief for tuberculosis, rheumatoid arthritis, and other ailments for which the medical profession had no cure. Some sought the mountain air of the Swiss Alps while others headed to the French and Italian Riviera. A smaller, more eclectic group made their way to San Diego, an up-and-coming tourist destination that promised plenty of sunshine, fresh air, and a mild, dry climate thought to be well-suited to damaged lungs and aching joints. Among them was the best-selling British novelist Beatrice Harraden who wrote several books about Southern California, including …


The Effect Of Nutrition And Exercise On Mental Health, Rebekah Owen 2021 Liberty University

The Effect Of Nutrition And Exercise On Mental Health, Rebekah Owen

Senior Honors Theses

Research has shown nutrition and exercise are especially effective in helping relieve mental illness. Mental health can be aided through dietary alterations such as increasing intake of omega-3 fatty acids, fermented foods, certain vitamins, minerals, and amino acids. Proper nutritional patterns help regulate neurotransmitters and assist in the betterment of brain functioning, offering protection from and maintenance of mental illness. Furthermore, the Mediterranean diet provides to be most beneficial for mental health compared to the standard American diet which contains additives harmful to the human brain. Physical exercise also provides to be a possible therapy for those suffering from mental …


The Utilization And Effectiveness Of Telemedicine In The Wake Of Covid-19, Maxwell Sharawy 2021 University of South Carolina - Columbia

The Utilization And Effectiveness Of Telemedicine In The Wake Of Covid-19, Maxwell Sharawy

Senior Theses

The COVID-19 pandemic devastated the world, in every industry. Almost none were hit as hard as the healthcare system. Through the use of telemedicine, healthcare providers were able to care for their patients without rise of infection. Through a review of published literature and interviews conducted with three practicing physicians of various specialties, a diagnosis was developed to determine if the care provided through telemedicine was as effective as in-person care. It was hypothesized that when used properly, telemedicine can be used as an effective replacement for in-person care across a wide range of specialties. After review of the literature …


Use Of A Zebrafish Model To Identify Anticonvulsant Properties Of Cannabinoid And Terpenoid Extracts And Mixtures, Courtney Murr 2021 Louisiana State University

Use Of A Zebrafish Model To Identify Anticonvulsant Properties Of Cannabinoid And Terpenoid Extracts And Mixtures, Courtney Murr

LSU Master's Theses

Epilepsy is a complex group of neurological disorders affecting approximately 65 million people worldwide. Animal models reveal the activation of cannabinoid receptor 1 and cannabinoid receptor 2 reduces the severity of seizures associated with epilepsy. Trials of phytocannabinoids in mammals demonstrate their efficacy of reducing the severity of epileptic seizures. Numerous terpenoid compounds are present in Cannabis plants but most have yet to be clinically investigated. The goal of this research was to use zebrafish (Danio rerio) to identify the potential anticonvulsive properties of phytocannabinoid and terpenoid compounds. During acute cannabinoid exposures, 7-days-post-fertilization (7 dpf) zebrafish larvae were …


James's Choice: Treating An Infant With Craniosacral Therapy (Cst), Veronica Quarry 2021 Thom Charles River Early Intervention

James's Choice: Treating An Infant With Craniosacral Therapy (Cst), Veronica Quarry

Journal of Transformative Touch

No abstract provided.


Anti‑Estrogenic And Anti‑Aromatase Activities Of Citrus Peels Major Compounds In Breast Cancer, Maha Salama, Dina Mahmoud ElKersh, Shahira M. Ezzat, Yasmeen Attiaa, Engy A. Mahrous, Mohey ElMazar 2021 The British University in Egypt

Anti‑Estrogenic And Anti‑Aromatase Activities Of Citrus Peels Major Compounds In Breast Cancer, Maha Salama, Dina Mahmoud Elkersh, Shahira M. Ezzat, Yasmeen Attiaa, Engy A. Mahrous, Mohey Elmazar

Pharmacy

Estrogen signaling is crucial for breast cancer initiation and progression. Endocrine-based therapies comprising estrogen receptor (ER) modulators and aromatase inhibitors remain the mainstay of treatment. This study aimed at investigating the antitumor potential of the most potent compounds in citrus peels on breast cancer by exploring their anti-estrogenic and anti-aromatase activities. The ethanolic extract of different varieties of citrus peels along with eight isolated flavonoids were screened against estrogen-dependent breast cancer cell lines besides normal cells for evaluating their safety profile. Naringenin, naringin and quercetin demonstrated the lowest IC50s and were therefore selected for further assays. In silico molecular modeling …


The Bioactivities Of Resveratrol And Its Naturally Occurring Derivatives On Skin, Ming-Hsien Lin, Chi-Feng Hung, Hsin-Ching Sung, Shih-Chun Yang, Huang-Ping Yu, Jia-You Fang 2021 Chi Mei Medical Center, Taiwan

The Bioactivities Of Resveratrol And Its Naturally Occurring Derivatives On Skin, Ming-Hsien Lin, Chi-Feng Hung, Hsin-Ching Sung, Shih-Chun Yang, Huang-Ping Yu, Jia-You Fang

Journal of Food and Drug Analysis

Resveratrol has been extensively reported as a potential compound to treat some skin disorders, including skin cancer, photoaging, allergy, dermatitis, melanogenesis, and microbial infection. There has been an increasing interest in the discovery of cosmetic application using resveratrol as the active ingredient because of its anti-aging and skin lightening activities. The naturally occurring derivatives of resveratrol also exert a beneficial effect on the skin. There are four groups of resveratrol derivatives, including hydroxylated compounds, methoxylated compounds, glycosides, and oligomers. The major mechanism of resveratrol and its derivatives for attenuating cutaneous neoplasia, photoaging and inflammation, are related with its antioxidative activity …


Deconstructing Patriarchy In The Healing Arts, Rebekah Harbour 2021 Zero Balancing

Deconstructing Patriarchy In The Healing Arts, Rebekah Harbour

Journal of Transformative Touch

Sometimes we perpetuate the very systems we want to change because it's the only way we know. Making a change in the outer world can require a shift in our inner perspective.


An In Vitro Study Of Hydrangea Arborescens, Homoeopathic Preparation As An Inhibitor Of Calcium Oxalate Crystallisation, Rupali Telang 2021 Department of Homoeopathy Pharmacy, KLE Homoeopathic Medical College, Belagavi, Karnataka

An In Vitro Study Of Hydrangea Arborescens, Homoeopathic Preparation As An Inhibitor Of Calcium Oxalate Crystallisation, Rupali Telang

Indian Journal of Research in Homoeopathy

Background: Homoeopathic mother tincture Hydrangea arborescens (Hydrang.) is conventionally used for urinary complaints, such as urinary tract infection, renal stones and prostate hypertrophy. However, the mode of its action for annihilation of complaints remains uncertain. This study was designed to investigate in vitro effect of homoeopathic preparations of Hydrang. on urolithiasis (Calcium oxalate [CaOx] crystallisation). Objective: To analyse the role of Hydrang. a, homoeopathic preparation in an in-vitro CAOx crystallisation. Materials and Methods: Spectrophotometric crystallisation assay was carried on and the slopes of nucleation and aggregation phases were calculated using linear regression analysis, and the percentage inhibition exerted by the …


Preclinical Updates Of The Homoeopathic Medicines Used In Diabetes Mellitus: A Narrative Review, G Kumar, V Chitra, Pankaj Gupta, Bibaswan Biswas, Arya Renu 2021 Department of Drug Standardization, Dr. Anjali Chatterji Regional Research Institute for Homoeopathy, Central Council for Research in Homoeopathy, Kolkata, West Bengal

Preclinical Updates Of The Homoeopathic Medicines Used In Diabetes Mellitus: A Narrative Review, G Kumar, V Chitra, Pankaj Gupta, Bibaswan Biswas, Arya Renu

Indian Journal of Research in Homoeopathy

Introduction: Homoeopathy, one of the most commonly employed alternative medicines globally, has a wide range of role in the management of diabetes. Screening of the action of homoeopathic medicines in diabetes on animal model not only helps in validating their antidiabetic potential but also aids in understanding their effect on living systems and their mechanism of action. The present review focusses on the collection of results of pre-clinical studies carried out on homoeopathic medicines employed in the management of diabetes. Methodology: PubMed, HomBRex portal, and published literature such as library catalogue were searched up to November 2019. The search terms …


Obliteration Of Ranula With Homoeopathic Treatment: A Case Report, Partha Pal 2021 Dr. Anjali Chatterji Regional Research Institute (H), Kolkata, Under Central Council for Research in Homoeopathy, Ministry of AYUSH, Govt of India

Obliteration Of Ranula With Homoeopathic Treatment: A Case Report, Partha Pal

Indian Journal of Research in Homoeopathy

Introduction: Ranula is a soft translucent swelling that occurs in the floor of the mouth usually causing mild discomfort to the patient. Conventional therapeutic modalities range from the injection of sclerosing agents to various surgical techniques. Only a few documented cases with non-surgical management are available on literature search, as surgery is considered to be the mainstay for this clinical condition. Case Summary: This is a case of a female child with a painless, cystic swelling in the right side of the floor of the mouth of 3-month duration and another smaller painless cystic swelling on the inner side of …


Active Principle In Potentised Medicines: Nanoparticle Versus Quantum Domain – An Overview, Papiya Nandy, Durga Bhar 2021 Centre for Interdisciplinary Research and Education, Kolkata, West Bengal

Active Principle In Potentised Medicines: Nanoparticle Versus Quantum Domain – An Overview, Papiya Nandy, Durga Bhar

Indian Journal of Research in Homoeopathy

Background: The fact that homoeopathic medicines act even at very high dilutions has created a confusion amongst scientists. This led to different models such as formation of nanoparticles and memory of water. The basic question 'what is responsible for physiological activity of homoeopathic medicines' is yet to be answered conclusively. Objective: The objective of this overview was to find out if formation of nanoparticles or creation of quantum domain in the medium is responsible for the physiological activity of homoeopathic medicines. Methods: This overview is based on the experiments done between 2004 and 2019. Results: The succussion of the medicine …


Research Highlights, Sarita Gola, Parul Parul 2021 Senior Research Fellow, Central Council for Research in Homeopathy, New Delhi

Research Highlights, Sarita Gola, Parul Parul

Indian Journal of Research in Homoeopathy

No abstract provided.


Homoeopathy For Management Of Type 2 Diabetes Mellitus In A Patient Of Major Depressive Disorder - A Case Report, Karanpreet Nahar, Subhash Kaushik 2021 Central Council for Research in Homoeopathy, New Delhi

Homoeopathy For Management Of Type 2 Diabetes Mellitus In A Patient Of Major Depressive Disorder - A Case Report, Karanpreet Nahar, Subhash Kaushik

Indian Journal of Research in Homoeopathy

Introduction: Major depressive disorder in diabetic individuals represents a multifactorial phenomenon resulting from interactions between biological and psychosocial factors, which may intensify the probability of developing type 2 diabetes mellitus (T2DM) in otherwise healthy individuals. Case Summary: A case of T2DM is reported in a 38-year-old woman suffering from major depressive disorder who was treated successfully with individualised homoeopathic medicines. The patient reported to the Lifestyle Disorders clinic of Homoeopathic Hospital, Noida, with recently diagnosed diabetes of 8 months. After individualised homoeopathic treatment, the patient's fasting plasma glucose, postprandial glucose, HbA1c levels, fasting plasma insulin and Hamilton Depression Rating Scale …


Are We At The Crossroads For Integrative Medicine?, Anil Khurana 2021 Director General, CCRH

Are We At The Crossroads For Integrative Medicine?, Anil Khurana

Indian Journal of Research in Homoeopathy

No abstract provided.


Homoeopathic Treatment Of Women With Polycystic Ovarian Syndrome: A Prospective Observational Study, Girish Gupta, Naveen Gupta, Santosh Singh, Varanasi Roja, Dewan Deepti 2021 Homoeopathic Research Foundation, Lucknow, Uttar Pradesh

Homoeopathic Treatment Of Women With Polycystic Ovarian Syndrome: A Prospective Observational Study, Girish Gupta, Naveen Gupta, Santosh Singh, Varanasi Roja, Dewan Deepti

Indian Journal of Research in Homoeopathy

Background: Polycystic ovarian syndrome (PCOS) is one of the most common hormonal disorders among women of reproductive age group and a leading cause of female sub-fertility. Objectives: This study was conducted to evaluate the effect of individualised homoeopathy on clinical and hormonal profile in women suffering from PCOS. Materials and Methods: A prospective, observational study was conducted from July 2015 to June 2017 at Homoeopathic Research Foundation, Lucknow, in which 80 cases were screened, and 38 cases fulfilling the eligibility criteria were enrolled. Polycystic Ovary Syndrome Health-Related Quality of Life Questionnaire (PCOSQ) was used to evaluate the quality of life. …


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