Mitochondrial Degeneration Precedes The Development Of Muscle Atrophy In Progression Of Cancer Cachexia In Tumour-Bearing Mice,
2017
University of Texas at Tyler
Mitochondrial Degeneration Precedes The Development Of Muscle Atrophy In Progression Of Cancer Cachexia In Tumour-Bearing Mice, Jacob L. Brown, Megan E. Rosa-Caldwell, David E. Lee, Thomas A. Blackwell, Lemuel A. Brown, Richard A. Perry, Wesley S. Haynie, Justin P. Hardee, James A. Carson, Michael P. Wiggs, Tyrone A. Washington, Nicholas P. Greene
Health & Kinesiology Faculty Publications and Presentations
Background: Cancer cachexia is largely irreversible, at least via nutritional means, and responsible for 20–40% of cancer-related deaths. Therefore, preventive measures are of primary importance; however, little is known about muscle perturbations prior to onset of cachexia. Cancer cachexia is associated with mitochondrial degeneration; yet, it remains to be determined if mitochondrial degeneration precedes muscle wasting in cancer cachexia. Therefore, our purpose was to determine if mitochondrial degeneration precedes cancer-induced muscle wasting in tumour-bearing mice. Methods: First, weight-stable (MinStable) and cachectic (MinCC) ApcMin/+ mice were compared with C57Bl6/J controls for mRNA contents of mitochondrial quality regulators in quadriceps muscle. Next, …
Understanding Why Undergraduate Students Declare And Continue To Study An Exercise Science-Related Major,
2017
University of Idaho
Understanding Why Undergraduate Students Declare And Continue To Study An Exercise Science-Related Major, Matthew Vaartstra, Vanessa Kercher, Amanda Start, Amber Brown, Mark Peterson, Ryan Mcgrath
International Journal of Exercise Science
International Journal of Exercise Science 10(5): 807-817, 2017. Understanding factors that contribute to a student’s selection of an exercise science-related major is important to student success, higher education and industry. This study sought to 1) better understand why undergraduate students study an exercise science-related major, 2) determine whether positive influences to study an exercise science-related major differ by academic classification, and 3) identify what student’s aspirations are after graduation. Department administrators from four-year colleges and universities offering an exercise science-related major in the Northwest Region of the United States (i.e., Idaho, Montana, Oregon, and Washington) were contacted. Cooperating department administrators …
Blood Pressure And Cardiovascular Health Has Relationship With Age In Adults During Adulthood,
2017
Washington University in St. Louis
Blood Pressure And Cardiovascular Health Has Relationship With Age In Adults During Adulthood, Allyson K. Getty, Jessica M. Lenzo, Tia R. Wisdo, Joyann E. Oakman, Christina M. Cromwell, Jessica A. Hill, Lauren N. Chavis, Deborah L. Feairheller, Phd
International Journal of Exercise Science
International Journal of Exercise Science 10(5): 798-806, 2017. Efforts to combat cardiovascular disease (CVD) have proven effective, especially in the population aged 55-74 years. However, less research has been conducted in younger populations to determine at what age CVD risk develops. The purpose of this study is to compare cardiovascular health markers in adults, specifically CVD risk between younger adults aged 18-22 and a slightly older group of adults in middle adulthood aged 23-54. Cardiovascular health measures were collected from a group of adults; 13 younger adults (20.2±0.9 yrs) and 10 adults in middle adulthood (42.9±10.1 yrs). All participants were …
Dynamics Of Stride Interval Characteristics During Continuous Stairmill Climbing,
2017
Charité–Universitätsmedizin Berlin
Dynamics Of Stride Interval Characteristics During Continuous Stairmill Climbing, Peter C. Raffalt, Srikant Vallabhajosula, Jessica J. Renz, Mukul Mukherjee, Nikolaos Stergiou
Journal Articles
It has been shown that statistical persistence in stride intervals characteristics exist during walking, running and cycling and were speed-dependent among healthy young adults. The purpose of this study was to determine if such statistical persistence in stride time interval, stride length and stride speed also exists during self-paced continuous stairmill climbing and if the strength is dependent on stepping rate. Stride time, stride length, and stride speed were collected from nine healthy participants during 3 min of stairmill climbing at 100, 110, and 120% of their preferred stepping rate (PSR) and 5 min of treadmill walking at preferred walking …
A Prospective Study Comparing Distance-Based Vs. Time-Based Exercise Prescriptions Of Walking And Running In Previously Sedentary Overweight Adults,
2017
Western Kentucky University
A Prospective Study Comparing Distance-Based Vs. Time-Based Exercise Prescriptions Of Walking And Running In Previously Sedentary Overweight Adults, Cody E. Morris, John C. Garner Iii, Scott G. Owens, Melinda W. Valliant, Hunter Debusk, Mark Loftin
International Journal of Exercise Science
International Journal of Exercise Science 10(5): 782-798, 2017. Prior work has reported that the declines observed in body mass index (BMI) and circumference measurements in their cross-sectional data were twice as large when calculated from distance energy expenditure estimations compared to energy expenditure estimations based on time and intensity. The primary purpose of this study was to compare walking/running for distance to walking/running for time as part of an exercise intervention. This study followed a between-subjects, repeated measures design. Fifteen overweight, but otherwise healthy participants completed the study. The time-based group walked/ran for self-reported time while the distance-based group walked/ran …
Run Economy On A Normal And Lower Body Positive Pressure Treadmill,
2017
SUNY-Cortland
Run Economy On A Normal And Lower Body Positive Pressure Treadmill, Corey Temple, Erik Lind, Deborah Van Langen, Larissa True, Saige Hupman, James F. Hokanson
International Journal of Exercise Science
International Journal of Exercise Science 10(5): 774-781, 2017. Lower body positive pressure (LBPP) treadmill running is used more frequently in clinical and athletic settings. Accurate caloric expenditure is required for proper exercise prescription, especially for obese patients performing LBPP exercise. It is unclear if running on LBPP changes running economy (RE) in proportion to the changes in body weight. The purpose of the study was to measure the oxygen consumption (VO2) and running economy (RE) of treadmill running at normal body weight and on LBPP. Twenty-three active, non-obese participants (25.8±7.2 years; BMI = 25.52±3.29 kg∙m-2) completed …
Wrist-Worn Physical Activity Trackers Tend To Underestimate Steps During Walking,
2017
Campbell University
Wrist-Worn Physical Activity Trackers Tend To Underestimate Steps During Walking, Tiffany Sears, Elmer Alvalos, Samantha Lawson, Ian Mcalister, L. Chris Eschbach, Jennifer Bunn
International Journal of Exercise Science
International Journal of Exercise Science 10(5): 764-773, 2017. The purpose of this study was to determine step-count accuracy of pedometers at different walking speeds. Ten recreationally active participants walked at five treadmill speeds (0.89, 1.11, 1.34, 1.56, and 1.79 m/s) for five minutes while wearing four wrist-worn activity trackers (Fitbit Charge HR®, Garmin Vivosmart HR®, Apple iWatch®, Jawbone UP3®) and the hip-worn Digi-Walker®. Each step was manually counted by a research technician (benchmark). Total step count at each speed was obtained for each device and compared to the benchmark using one-way MANOVA and Pearson correlation coefficient. For all five speeds, …
Examining The Impact Of A University-Driven Exercise Programming Event On End-Of-Semester Stress In Students,
2017
University of Nevada, Las Vegas
Examining The Impact Of A University-Driven Exercise Programming Event On End-Of-Semester Stress In Students, Tessa L. Koschel, John C. Young, James W. Navalta
International Journal of Exercise Science
International Journal of Exercise Science 10(5): 754-763, 2017. Stress levels in university students peak during the final exam period. An inverse association exists between Physical Activity (PA) and poor mental health. UNLV has created Fitness4Finals (F4F), an event novel in its approach to academic stress reduction by incorporating both physical activity and mental relaxation. To our knowledge, a university-driven programming event aimed at reducing physiological and psychological stress among students approaching final exams had never been studied. Therefore, the aims of this research were to 1) examine the influence of F4F on physiological stress and perceived psychological stress (PPS) and …
Changes In Gait And Texting Ability During Progressively Difficult Gait Tasks,
2017
Bradley University
Changes In Gait And Texting Ability During Progressively Difficult Gait Tasks, Andrew J. Strubhar, Brody Rapp, Dillon Thomas
International Journal of Exercise Science
International Journal of Exercise Science 10(5): 743-753, 2017. To investigate the effects of a cell phone texting task on an individual’s ability to perform three ambulation-based tasks, each with different and progressively more difficult demands. 36 participants (24 male/12 female, average age 23.4) performed: a Timed Up & Go (TUG), stair ambulation (STAIR), and tandem gait (TAN). Participants completed each gait-based task under four conditions: as a practice, while holding their cellular device (baseline), while texting a message, and while reading a message. Statistically significant differences were found within the following variables: 1) mean time to complete a gait task …
Recovery In Level 7-10 Usa Artistic Gymnastics,
2017
Arizona State University, Tempe
Recovery In Level 7-10 Usa Artistic Gymnastics, Stephen Buckner, Nicholas T. Bacon, Phillip Bishop
International Journal of Exercise Science
International Journal of Exercise Science 10(5): 734-742, 2017. This study assessed physical performance in women’s artistic gymnastics following three variable recovery periods. Participants included fifteen female gymnasts (mean age = 13.5 ± 1.1) who had competed at USA Gymnastics (USAG) levels 7 – 10 within at least one year prior to the study. Each testing session consisted of a warm-up followed by four muscular endurance tests and one explosive maximal test. Assessments included pull-ups, leg lifts, handstand push-ups, vertical jump, and push-ups. After the performance assessments, the participants completed a typical practice session. The performance measures were reassessed at the …
Fluid Intake And Sweat Rate During Hot Yoga Participation,
2017
Central Washington
Fluid Intake And Sweat Rate During Hot Yoga Participation, Stephanie Campbell, Robert C. Pritchett, Katie Cederburg, Tim Burnham, Kelly C. Pritchett
International Journal of Exercise Science
International Journal of Exercise Science 10(5): 721-733, 2017. Hot yoga participants are at risk for dehydration due to the nature of the environment they exercise in. Therefore, the purpose of this study was to investigate the pre-exercise hydration status, fluid balance, perception of sweat loss, and sweat sodium loss in 21 male and female hot yoga participants (mean age ± SD, 33.0 ± 10.5 yr; mass, 70.7 ± 11.0 kg). Data was recorded pre and post a one- hour hot yoga class (38.7 ± 2.6 °C, 36 ± 13% relative humidity). Pre-exercise urine specific gravity (USG), hydration status, body mass …
In-Season High-Intensity Interval Training Improves Conditioning In High School Soccer Players,
2017
Willamette University
In-Season High-Intensity Interval Training Improves Conditioning In High School Soccer Players, Neal Howard, Stasinos Stavrianeas
International Journal of Exercise Science
International Journal of Exercise Science 10(5): 713-720, 2017. Soccer is characterized by high aerobic demands interspersed with frequent bursts of anaerobic activity. High-intensity interval training (HIIT) is considered a viable alternative to traditional endurance conditioning and offers the additional time-saving benefits of anaerobic training. We hypothesized that HIIT will compare favorably to traditional (aerobic-based) soccer conditioning over the course of a high school soccer season. Junior varsity soccer players were split into control (CON, n=16) and experimental (HIIT, n=16) groups for the 10-week study. The HIIT group performed 4-6 “all-out” sprints lasting 30s each, with 4.5 minute recovery, 3 times …
Effect Of Sedentary And Physical Activities On Children’S Food Choice,
2017
North Dakota State University
Effect Of Sedentary And Physical Activities On Children’S Food Choice, Allison M. Barry, Jesse L. Rhoades, John S. Fitzgerald, Dennis J. Caine, Dalonda L. Dalin, Tanis J. Walch
International Journal of Exercise Science
International Journal of Exercise Science 10(5): 702-712, 2017. Childhood obesity is a growing public health concern. Research has shown sedentary behavior (SB) increases children’s unhealthy food consumption, while physical activity (PA) decreases caloric intake and increases energy expenditure. The purpose of this study was to examine child snack choice following a bout of active, SB, and a mix of SB and active (SB-A). Participants included a volunteer sample of children (n=24) ranging from 9-13 years of age. A within-subjects simple experimental design was used, and children participated in three conditions: active, SB, and SB-A. After each condition, the children were …
Pilot Study Of Endurance Runners And Brain Responses Associated With Delay Discounting,
2017
University of Kansas Medical Center
Pilot Study Of Endurance Runners And Brain Responses Associated With Delay Discounting, Laura E. Martin, Jason-Flor V. Sisante, David R. Wilson, Angela A. Moody, Cary R. Savage, Sandra A. Billinger
International Journal of Exercise Science
International Journal of Exercise Science 10(5): 690-701, 2017. High levels of endurance training have been associated with potentially negative health outcomes and addictive-like symptoms such as exercise in the presence of injury and higher levels of impulsivity. This pilot study examined the relationships among self-report measures of addictive symptoms related to exercise and behavioral and neural measures of impulsivity in endurance runners. We hypothesized endurance runners would have increased preference for immediate rewards and greater activation of cognitive control regions when making decisions involving delayed rewards. Twenty endurance runners (at least 20 miles/week) were recruited to undergo measures of self-report …
Clinical Outcomes Of Different Tempos Of Music During Exercise In Cardiac Rehabilitation Patients,
2017
Lower Columbia College
Clinical Outcomes Of Different Tempos Of Music During Exercise In Cardiac Rehabilitation Patients, Jarad S. Miller, Donna J. Terbizan
International Journal of Exercise Science
International Journal of Exercise Science 10(5): 681-689, 2017. This study examined the effects of stimulating and sedative music on ratings of perceived exertion (RPE), heart rate (HR), blood pressure (BP), and feeling status during exercise in cardiac rehabilitation (CR) patients. Twenty-two male and female older adults age 64 ± 8.0 y currently enrolled in phase III CR completed the study. Repeated measures crossover designs guided data collection. The manipulated independent variable was music condition (sedative, stimulating, and non-music control). The dependent variables were RPE, BP, HR, and feeling status with each represented by four repeated measures ANOVAs over time via …
Irisin And Fibronectin Type Iii Domain-Containing 5 Responses To Exercise In Different Environmental Conditions,
2017
University of Nebraska at Omaha
Irisin And Fibronectin Type Iii Domain-Containing 5 Responses To Exercise In Different Environmental Conditions, Matthew Bubak, Matthew W.S. Heesch, Robert J. Shute, Nicholas E. Dinan, Terence L. Laursen, D. Taylor La Salle, Dustin R. Slivka
International Journal of Exercise Science
International Journal of Exercise Science 10(5): 666-680, 2017. Fibronectin type III domain-containing 5 (FNDC5) is a skeletal muscle membrane-bound precursor to the myokine irisin. Irisin is involved in stimulating adipose tissue to become more metabolically active in order to produce heat. The purpose of this study was to determine the effects of exercise in a hot (33 °C), cold (7 °C), and room temperature (RT, 20 °C) environment on the skeletal muscle gene expression of FNDC5 and the plasma concentrations of irisin. Twelve recreationally trained males completed three separate, 1 h cycling bouts at 60% of Wmax in a …
The Effect Of Psychomotor Performance, Cerebral And Arterial Blood Saturation Between African-American And Caucasian Males Before, During And After Normobaric Hypoxic Exercise,
2017
Grand Valley State University
The Effect Of Psychomotor Performance, Cerebral And Arterial Blood Saturation Between African-American And Caucasian Males Before, During And After Normobaric Hypoxic Exercise, Matthew R. Feeback, Yongsuk Seo, Matthew Dancy, Ellen L. Glickman
International Journal of Exercise Science
International Journal of Exercise Science 10(5): 655-665, 2017. To further elucidate physiological and cognitive performance differences between African-American (AA) and Caucasian individuals (CAU) before, during or after hypoxic and normoxic exercise. Twelve college aged (18-25) apparently healthy African-American (six volunteers) and Caucasian (six subjects) males took part in two trials consisting of normobaric normoxia and normobaric hypoxia (12% oxygen). Each subject cycled at 50% of their altitude adjusted VO2max (-26% of normoxia VO2max) for one hour after a two-hour baseline. Subjects were monitored for cerebral and arterial O2 saturation, as well as the Trail Making Test …
Blood Flow Restriction Training: Implementation Into Clinical Practice,
2017
Western Kentucky University
Blood Flow Restriction Training: Implementation Into Clinical Practice, William R. Vanwye, Alyssa Weatherholt, Alan E. Mikesky
International Journal of Exercise Science
International Journal of Exercise Science 10(5): 649-654, 2017. To improve muscular strength and hypertrophy the American College of Sports Medicine recommends moderate to high load resistance training. However, use of moderate to high loads are often not feasible in clinical populations. Therefore, the emergence of low load (LL) blood flow restriction (BFR) training as a rehabilitation tool for clinical populations is becoming popular. Although the majority of research on LL-BFR training has examined healthy populations, clinical applications are emerging. Overall, it appears BFR training is a safe and effective tool for rehabilitation. However, additional research is needed prior to widespread …
On The Rules For Aquatic Locomotion,
2017
Harvard University
On The Rules For Aquatic Locomotion, M. Saadat, Frank E. Fish, A. G. Domel, G. V. Lauder, H. Haj-Hariri
Biology Faculty Publications
We present unifying rules governing the efficient locomotion of swimming fish and marine mammals. Using scaling and dimensional analysis, supported by new experimental data, we show that efficient locomotion occurs when the values of the Strouhal (St) number St(=f A/U) and A∗(=A/L), two nondimensional numbers that relate forward speed U, tail-beat amplitude A, tail-beat frequency f , and the length of the swimmer L are bound to the tight ranges of 0.2–0.4 and 0.1–0.3, respectively. The tight range of 0.2–0.4 for the St number has previously been associated with optimal thrust generation. We show that the St number alone is …
Mechanobiology Of Epithelial Clusters In Ecms Of Diverse Mechanical Properties,
2017
Washington University in St. Louis
Mechanobiology Of Epithelial Clusters In Ecms Of Diverse Mechanical Properties, Samila Nasrollahi
McKelvey School of Engineering Graduate Student Theses & Dissertations
Cell clusters reside in complex extracellular matrices (ECMs) of varying mechanical properties. Epithelial cells sense and translate the mechanical cues presented by the surrounding ECM into biochemical signals through a process called ‘mechanotransduction’, which controls fundamental aspects of disease and development. During the course of metastasis, mechanical changes in the tumor microenvironment can lead to declustering of epithelial cells through a process called epithelial-to-mesenchymal transition (EMT). Throughout different steps of metastasis, escaped epithelial clusters encounter heterogeneous tissues of varying mechanical properties that ultimately influence their behavior in distant locations within the body. This dissertation investigates the mechanobiology of epithelial clusters …
