Kinesiology Commons^™

Decoding Human Movement Through Experiments And Simulation, Vishnu Deep Chandran

Dissertations

The ability to walk or move independently plays a decisive role in one's quality of life. This human ability requires complex coordination with several systems, such as the nervous, muscular, skeletal, and sensory organs, to execute movement tasks. Hence, any disorder of these systems from injury, disease, or aging severely affects the ability to walk or move independently. Disabilities that impair movement severely affect the quality of life. Therefore, studying the changes affecting human movement is necessary to improve the lives of individuals with impaired movement. Since human movement is complex and many systems interact in non-intuitive ways, the overarching …

Machine Learning-Based Peripheral Artery Disease Identification Using Laboratory-Based Gait Data, Ali Al-Ramini, Mahdi Hassan, Farah Fallahtafti, Mohammad Ali Takallou, Hafizur Rahman, Basheer Qolomany, Iraklis Pipinos, Fadi Alsaleem, Sara A. Myers

Journal Articles

Peripheral artery disease (PAD) manifests from atherosclerosis, which limits blood flow to the legs and causes changes in muscle structure and function, and in gait performance. PAD is underdiagnosed, which delays treatment and worsens clinical outcomes. To overcome this challenge, the purpose of this study is to develop machine learning (ML) models that distinguish individuals with and without PAD. This is the first step to using ML to identify those with PAD risk early. We built ML models based on previously acquired overground walking biomechanics data from patients with PAD and healthy controls. Gait signatures were characterized using ankle, knee, …

Application Of Polynomial Regression Model For Joint Stiffness, Youngmin Chun, Craig Mcgowan, Jinah Kim, Joshua P. Bailey

International Journal of Exercise Science

International Journal of Exercise Science 15(1): 1236-1245, 2022. Quasi-stiffness (joint stiffness) is often used to characterize leg properties during athletic and other activities and has been reported by a single slope of angle-moment curve. However, the joint angle-moment relationship of some relationship are not effectively represented by a simple linear regression model. Thus, the purpose of this analysis was to investigate the benefits of utilizing a 2^nd order polynomial regression (quadratic) model as compared to the linear model when calculating lower extremity joint stiffness incorporating subdivided eccentric phases. Thirty healthy and active college students performed 15 drop jumps from …

Whole Genome Association Study Of The Plasma Metabolome Identifies Metabolites Linked To Cardiometabolic Disease In Black Individuals, Usman A. Tahir, Daniel H. Katz, Julian Avila-Pachecho, Alexander G. Bick, Akhil Pampana, Jeremy M. Robbins, Zhi Yu, Zsu-Zsu Chen, Mark D. Benson, Daniel E. Cruz, Debby Ngo, Shuliang Deng, Xu Shi, Shuning Zheng, Aaron S. Eisman, Laurie Farrell, Michael E. Hall, Adolfo Correa, Russell P. Tracy, Peter Durda, Mark A. Sarzynski Ph.D., Faha, Facsm, Et. Al.

Faculty Publications

Integrating genetic information with metabolomics has provided new insights into genes affecting human metabolism. However, gene-metabolite integration has been primarily studied in individuals of European Ancestry, limiting the opportunity to leverage genomic diversity for discovery. In addition, these analyses have principally involved known metabolites, with the majority of the profiled peaks left unannotated. Here, we perform a whole genome association study of 2,291 metabolite peaks (known and unknown features) in 2,466 Black individuals from the Jackson Heart Study. We identify 519 locus-metabolite associations for 427 metabolite peaks and validate our findings in two multi-ethnic cohorts. A significant proportion of these …

Co-Twin Relationship Quality As A Moderator Of Genetic And Environmental Factors On Urinary Cortisol Levels Among Adult Twins, Joseph A. Schwartz, Scott Jessick, Jessica L. Calvi, Douglas A. Granger

Athletic Performance Research

Previous research has indicated that genetic and environmental factors shape physiological activity. Cortisol levels, in particular, have received significant attention, with studies indicating substantive heritability estimates across various sampling techniques. A related line of research has indicated that genetic and environmental factors that explain variability in cortisol levels may vary across context and experiences by way of gene-environment interactions (G×Es). Despite these findings, a limited number of studies have examined the extent to which interpersonal relationships may operate as a moderator. The current study focused on co-twin relationship quality as a source of moderation, as twins are more likely to …

Energy Cost Of Reclining, Sitting, And Standing Activities In Chinese Adults, Jiajia Liu, Yiyan Li, Minghui Quan, Jie Zhuang, Zhen-Bo Cao, Zheng Zhu, Yongming Li, Stephen D. Herrmann, Barbara E. Ainsworth

International Journal of Exercise Science

International Journal of Exercise Science 15(7): 1202-1211, 2022. The 2011 Compendium presents MET values for sedentary behaviors (SBs) and light-intensity physical activities (LIPAs). Some entries have estimated METs, others have multiple activities in a single entry, and newer activities are not in the Compendium. Accurate MET values are needed to increase the validity and generalizability of the Compendium. This study measured and analyzed SBs and LIPAs’ energy costs in reclining, sitting, standing postures, and fidgeting. Indirect calorimetry measured the energy costs (VO₂, ml^.kg^-1.min^-1) in 11 males and seven females (30.7 ± 7.6 …

Differences In Rate Of Perceived Exertion And Workload Intensity In Males And Females During Submaximal Arm And Leg Ergometry, Konrad J. Dias, Amanda Mungenast, Stephanie Sherwood, Patrick Mcpherson, Allison Verville, Shannon Eaton, Dustin Nadler

International Journal of Exercise Science

International Journal of Exercise Science 15(4): 1222-1235, 2022. Purpose: Arm ergometry (AE) is necessitated for individuals unable to perform leg ergometry (LE) exercise. This study explored gender differences in RPE and workload (WL) during AE and LE at submaximal target heart rates (THR). Methods: 35 healthy college-aged individuals were randomly allocated to begin exercise on either AE or LE. Participants exercised on both modes with increasing WL to achieve submaximal THRs of 110, 120, 130, 140 and 150 beats per minute (bpm). Factorial ANOVAs tested for differences in RPE and WL. Results: No significant differences were found in RPE between …

Effects Of Varying Load Intensity On Skeletal Muscle Damage Between Two Isovolumic Resistance Exercise Bouts, Lee J. Winchester, Cody E. Morris, Patton Allen, Teresa Wiczynski, Scott W. Arnett, T. Scott Lyons

International Journal of Exercise Science

International Journal of Exercise Science 15(4): 1212-1221, 2022. There are limited data comparing the efficacy of resistance loads within the hypertrophy range for promoting muscular growth, particularly when similar training volumes are utilized. The purpose of this study was to determine if two similar volume-loads, utilizing different intensities, would produce dissimilar muscular damage and inflammation. Eleven resistance-trained, college-aged males participated in this study. After testing 1RM barbell squats, participants completed two similar volume-load barbell squat sessions at two different resistance loads (67% and 85% of 1RM) on two separate visits. Venous blood samples were collected at baseline and one hour …

Sex Differences In Measures Of Wave Reflection And Aortic Arterial Stiffness In Response To Weight Machine Resistance Exercise, Emily K. Erb, Stacie Humm, Sarah Kearney, Anthony G. Pinzone, Michelle A. Kern, J. Derek Kingsley

International Journal of Exercise Science

International Journal of Exercise Science 15(2): 1190-1201, 2022. While it has been demonstrated that acute resistance exercise (RE) alters measures of wave reflection and aortic arterial stiffness in young, healthy individuals, limited research has evaluated sex differences. Accordingly, we recruited moderately active, resistance-trained men (Age: 22 ± 3yrs, n=12) and women (23 ± 3yrs, n=10) to perform two randomized conditions consisting of an acute bout of weight machine RE or a quiet control (CON). Measures of aortic wave reflection and aortic stiffness were taken at baseline and 15 minutes following the RE (Recovery). At baseline, women had significantly higher heart …

Body Composition Of Utah Highway Patrol Officers: No Difference Between Air Displacement Plethysmography And Alternative Tools For Measurement And Prediction., Peter Macgregor, Justin R. Brown, Jacqueline Spoon, L Nathan Thomas

Topics in Exercise Science and Kinesiology

Topics in Exercise Science and Kinesiology Volume 3: Issue 1, Article 6, 2022. Different techniques exist for examining body composition. The purpose of this study was to examine differences in body fat percentage as measured by air displacement plethysmography (ADP), body adiposity index (BAI), bioelectrical impedance (BIA), a body mass index conversion equation (BMI_D), and skinfolds (SKF). Twenty-one male Utah Highway Patrol Officers participated in this study (age 35.19 ± 10.32 years, 1.79 ± 0.09 m tall, 92.20 ± 14.56 kg in weight, and 105.52 ± 10.01 cm hip circumference). All measurements were taken during a single visit …

The Effects Of A Multi-Ingredient Supplement On Various Cognitive Measures, Jason M. Curtis, Cassandra Evans, Veronica Mekhail, Paulina Czartoryski, Juan Carlos Santana, Jose Antonio

Journal for Sports Neuroscience

The purpose of this study was to investigate the effects of a multi-ingredient pre-workout supplement (MIPS) on mental and physical performance. Seventeen exercise-trained men (n = 7) and women (n=10) completed this randomized, placebo-controlled, double-blind, counterbalanced, crossover trial. Participants consumed either a multi-ingredient pre-workout supplement (MIPS) or a placebo in a randomized, counterbalanced order. Forty-five minutes post-consumption, the following assessments were conducted: psychomotor vigilance test (PVT), Profile of Mood States (POMS), Stroop test, vertical jump test, and a Cold pressor test. There was a one-week washout period between assessments. There were significant differences in the incongruent task for the Stroop …

Modeling, Analysis, And Simulation To Reveal The Mechanisms Of Ciliary Beating, Louis Woodhams

McKelvey School of Engineering Graduate Student Theses & Dissertations

Cilia are microscopic cellular appendages that help us breathe by clearing our airways, maintain the health of our central nervous system by circulating cerebrospinal fluid, and allow us to reproduce by transporting eggs and propelling sperm cells. Cilia even determine the asymmetry of our internal organs during embryonic development. However, the mechanisms underlying ciliary beating are not fully understood. Questions remain as to how arrays of the motor protein dynein generate the propulsive waveforms observed in cilia and how structural elements within the cilium and its connection to the cell deform during beating. In the current work, mathematical modeling, analysis, …

Advancing The Assessment And Treatment Of Signs And Symptoms Of Parkinson Disease, David Scott May

WUSM Theses and Dissertations – All Programs

People with PD often report signs and symptoms that negatively impact quality of life. Among these are balance difficulties, impaired gait, and FOG. New treatment and assessment strategies for these signs and symptoms are needed, as current techniques are limited. While new treatment and assessment strategies continue to emerge, gaps in knowledge persist. Deep brain stimulation (DBS) has been utilized in many people with PD throughout the 21st century, but it is unknown specifically how subthalamic nucleus deep brain stimulation (STN-DBS) affects balance. Alternative treatment strategies, such as a dental mouthpiece, have also been proposed. While dental mouthpieces have shown …

Expiratory Flow Limitation In Youth Endurance-Trained And Recreationally Active Females, Sarah Ridgeway

Masters Theses, 2020-current

The purpose of this study was to investigate the presence of expiratory flow limitation (EFL) in endurance trained (ET) youth females compared to a recreationally active (RA) group. EFL has been reported in ET males of pubertal age, however, the presence of EFL in ET youth females is not established. Methods: Youth ET female subjects (n=9, 15.8 ± 1.1 years) and RA subjects (n=10, 16.8 ± 1.6 years) completed an incremental exercise test to exhaustion on a cycle ergometer to determine peak oxygen consumption (VO_2peak). Maximum flow volume loops (MFVL), forced vital capacity (FVC), forced expiratory volume in …

The Role Of Ot In Adapted Crossfit, Emily Adams

Student Capstone Papers

Background: A quarter of adults are diagnosed with a disability in the United States, with almost half considered being inactive (CDC, 2020). The population of persons with disabilities (PWD) are at higher risk for secondary health concerns due to a sedentary lifestyle (Diaz et al., 2019). CrossFit recently implemented their first adaptive division in 2021 (CrossFit, LLC, 2022), however there continue to be barriers preventing PWD from participating in CrossFit.

Problem/Purpose: PWD may experience limited access to CrossFit due to structural and social barriers to access equipment and participating in movements. The purpose of this project was to …

A Biomechanical Approach To Prevent Falls In Ergonomic Settings, Sachini Kodithuwakku Arachchige

Theses and Dissertations

Introduction: Fall-related injuries are exceptionally prevalent in occupational settings. While endangering the workers’ health, falls cause poor productivity and increased economic burden in the workplace. Hence, identifying these threats and training workers to achieve proper postural control is crucial. Purpose: Study 1: To investigate the ankle joint kinematics in unexpected and expected trip responses during single-tasking (ST), dual-tasking (DT), and triple-tasking (TT), before and after a physically fatiguing exercise. Study 2: To investigate the impact of virtual heights, DT, and training on static postural stability and cognitive processing. Methods: Study 1: Twenty collegiate volunteers (10 males and females, one left …

Efficacy Of A 6-Week Suspension Training Exercise Program On Fitness Components In Older Adults, Christina Pierle, Alexander T. Mcdaniel, Lindsey H. Schroeder, Michel J.H. Heijnen, Wayland Tseh

International Journal of Exercise Science

International Journal of Exercise Science 15(3): 1168-1178, 2022. The purpose of this study was to determine the efficacy of a 6-week suspension training exercise program on fitness components in older adults. Eleven participants (age = 80 ± 5 yrs) completed a 6-week suspension training exercise program. Pre- and post-fitness assessments comprised of body composition, handgrip dynamometer, functional reach, and balance. The 6-week suspension training intervention required individuals to perform suspension training exercises for fifty minutes, twice per week. A paired sample t-test was used to determine differences from pre-and post-assessments. An improvement was observed in functional reach (57.2 ± …

The Association Between Handgrip Strength Asymmetry Severity And Future Morbidity Accumulation: Results From The Health And Retirement Study, Lukus Klawitter, Kyle Collins, Dawson Ringhofer, Bryan Christensen, Ryan Mcgrath

International Journal of Exercise Science

International Journal of Exercise Science 15(3): 1133-1141, 2022. Analyzing the severity of handgrip strength (HGS) asymmetry in aging populations may help to screen for morbidities and add utility to handgrip dynamometer testing. Our study sought to determine the relationships between HGS asymmetry severity and future accumulating morbidities in older Americans. Secondary analyses from the 2006-2016 waves of the Health and Retirement Study included 18,506 adults ≥ 50 years old. The highest recorded HGS values from each hand were used to calculate HGS asymmetry ratio (non-dominant HGS/dominant HGS). If the HGS asymmetry ratio < 1.0, it was inversed to make all asymmetry ratios ≥ 1.0. Participants were categorized into groups based on the severity of their HGS asymmetry ratio: 1) 0.0% - 10.0%, 2) 10.1% - 20.0%, 3) 20.1% - 30.0%, and 4) > 30.0%. Healthcare provider-diagnosed morbidities (hypertension, diabetes, cancer, chronic …

Impact Of Acute Uninterrupted Sitting On Cerebrovascular Hemodynamics, Raymond Jones, Dominique Mcarthur, Stephanie Mccoy, Lee Stoner, Simon Fryer, Daniel P. Credeur

International Journal of Exercise Science

International Journal of Exercise Science 15(2): 1156-1167, 2022. Reductions in brain blood flow are associated with reduced cognitive function and cerebrovascular disease. Acute periods of uninterrupted sitting can lead to endothelial dysfunction, namely due to a reduction in shear stress and subsequent reduction in nitric oxide bioavailability. Little is known of the impact of sitting on brain health. The purpose was to determine the total brain blood flow response following a 60-minute bout of uninterrupted sitting. Using a parallel design, this study evaluated the impact of 60-minutes of sitting on total brain blood flow. Fifteen participants (n=15; age=24 ± …

Effects Of Creatine Supplementation And Progressive Resistance Training In Stroke Survivors, Sara Butchart, Darren G. Candow, Scott Forbes, Cameron Mang, Julianne Gordon, Jongbum Ko, Dalton Deprez, Phil Chilibeck, David Ditor

International Journal of Exercise Science

International Journal of Exercise Science 15(2): 1117-1132, 2022. The purpose was to investigate the effects of progressive resistance training (PRT) and creatine supplementation in stroke survivors. Participants were randomized to one of two groups: creatine (n = 5; 51 ± 16y) or placebo (n = 3; 73 ± 8y) during 10 weeks of supervised PRT. Prior to and following PRT and supplementation, assessments were made for body composition (lean tissue and fat mass), muscle thickness, muscle strength (1-repetition maximum), functional exercise capacity (6-minute walk test, Berg Balance Scale; BBS), cognition (Montreal Cognitive Assessment; MoCA), and symptoms of anxiety …