Exercise Science Commons^™

Longitudinal Associations Between Waking Movement Behaviors And Health-Related Quality Of Life In Older Adults: A Compositional Data Analysis Approach, Jaclyn P. Maher, Alexander Jochim, Yeongjun Seo, Brynn L. Hudgins, Iman F. Khan, Peyton A. Greco, Emily M. Postlehwait, Om L. Patel, Krista S. Leonard, Chih-Hsiang Yang, Denver M. Y. Brown

Faculty Publications

Objectives

Movement behaviors, such as sedentary behavior (SB), light intensity physical activity (LPA), and moderate to vigorous intensity physical activity (MVPA) are mutually exclusive, in that time spent in one behavior inevitably displaces time spent in another. Yet, few studies have simultaneously considered these health behaviors and their association with health-related quality of life (HRQoL), an important indicator of health and well-being in aging populations. This study aimed to explore the role of waking movement behaviors (i.e., SB, LPA, MVPA) in prospectively predicting HRQoL in older adults. The study further aimed to cross-validate associations between movement behaviors and HRQoL using …

A Caffeine And Theacrine Combination Improves Cognitive Performance In Tactical Personnel Under Physically Fatiguing Conditions, Blaine S. Lints, Adam T. Harrison, Sten O. Stray-Gundersen, Gianna F. Mastrofini, Riccardo F. Romersi, Noah K. Nakagawa, Mackenzie B. Yonder, Chimaobim E. Martin-Diala, Alexa J. Chandler, R. Davis Moore, Shawn M. Arent Ph.D., Cscs*D, Fissn, Facsm, Fnak

Faculty Publications

Background

Optimizing human performance under stressful physical and cognitive conditions is paramount during high-stakes military operations. As such, interventions to improve warfighter performance by mitigating task-induced cognitive performance deficits are necessary. While caffeine is the most widely consumed psychoactive substance in the world, common side effects (i.e. anxiousness, micro-saccades, irritability) may be detrimental to warfighter operations. Theacrine, a purine alkaloid similar in structure to caffeine but with a longer half-life, less habituation, and fewer side effects, is proposed as a caffeine-alternative to enhance cognitive resilience.

Methods

Tactically trained participants (n = 20; F = 5; M = 16; age …

Designing Context-Specific Physical Activity Interventions For English Primary Schools: Key Learning From A Four-Month Rapid Ethnography, Robert Walker, Danielle House, Simona Kent-Saisch, Alice Porter, Ruth Salway, Lydia Emm-Collison, Michael W. Beets Med, Mph, Phd, David Revalds Lubans, Frank De Vocht, Russell Jago

Faculty Publications

Background

Physical activity is essential for children’s health. Primary schools offer an opportunity to equitably promote physical activity. However, school-based interventions have been shown to have little to no effect, potentially due to a lack of consideration of school heterogeneity. This study reports on a rapid ethnography study that was used to capture insights into English primary schools physical activity. The data are intended to inform the design of a context-specific intervention to improve pupil physical activity.

Methods

Three researchers conducted a four-month rapid ethnography study within three primary schools in Bristol, UK, between March and July 2024. Several methods …

Designing Context-Specific Physical Activity Interventions For English Primary Schools: Key Learning From A Four-Month Rapid Ethnography, Robert Walker, Danielle House, Simona Kent-Saisch, Alice Porter, Ruth Salway, Lydia Emm-Collison, Michael Beets Med, Mph, Phd, David Revalds Lubans, Frank De Vocht, Russell Jago

Faculty Publications

Background

Physical activity is essential for children’s health. Primary schools offer an opportunity to equitably promote physical activity. However, school-based interventions have been shown to have little to no effect, potentially due to a lack of consideration of school heterogeneity. This study reports on a rapid ethnography study that was used to capture insights into English primary schools physical activity. The data are intended to inform the design of a context-specific intervention to improve pupil physical activity.

Methods

Three researchers conducted a four-month rapid ethnography study within three primary schools in Bristol, UK, between March and July 2024. Several methods …

Predicting Sleep And Sleep Stage In Children Using Actigraphy And Heartrate Via A Long Short-Term Memory Deep Learning Algorithm: A Performance Evaluation, Robert Weaver Med, Phd, James White, Olivia Finnegan, Hongpeng Yang, Zifei Zhong, Keagan Kiely, Catherine Jones, Yan Tong, Srihari Nelakuditi, Rahul Ghosal, David E. Brown, Russell R. Pate Ph.D., Gregory J. Welk, Massimiliano De Zambotti, Yuan Wang, Sarah Burkart, Elizabeth L. Adams Phd, Bridget Armstrong, Michael Beets Med, Mph, Phd

Faculty Publications

Children's ambulatory sleep is commonly measured via actigraphy. However, traditional actigraphy measured sleep (e.g., Sadeh algorithm) struggles to predict wake (i.e., specificity, values typically < 70) and cannot predict sleep stages. Long short-term memory (LSTM) is a machine learning algorithm that may address these deficiencies. This study evaluated the agreement of LSTM sleep estimates from actigraphy and heartrate (HR) data with polysomnography (PSG). Children (N = 238, 5–12 years,52.8% male, 50% Black 31.9% White) participated in an overnight laboratory polysomnography. Participants were referred be-cause of suspected sleep disruptions. Children wore an ActiGraph GT9X accelerometer and two of three consumer wearables(i.e., Apple Watch Series 7, Fitbit Sense, Garmin Vivoactive 4) on their non-dominant wrist during the polysomnogram. LSTM estimated sleep versus wake and sleep stage (wake, not-REM, REM) using raw actigraphy and HR data for each 30-s epoch. Logistic regression and random forest were also estimated as a benchmark for performance with which to compare the LSTM results. A 10-fold cross-validation technique was employed, and confusion matrices were constructed. Sensitivity and specificity were calculated to assess the agreement between research-grade and consumer wearables with the criterion polysomnography. For sleep versus wake classification, LSTM outperformed logistic regression and random forest with accuracy ranging from 94.1to 95.1, sensitivity ranging from 94.9 to 95.9 across different devices, and specificity ranging from 84.5 to 89.6. The addition of HR improved the prediction of sleep stages but not binary sleep versus wake. LSTM is promising for predicting sleep and sleep staging from actigraphy data, and HR may improve sleep stage prediction.

To Play Or Not To Play: Investigating The Effects Of Auditory Stimuli During Running, Anna L. Tamblyn, Jodi Brandt, Chloe Schmidt, Grace Barnett, Danielle Kern

2025 Symposium

Research has shown that listening to music during physical activity can have a positive effect on emotional state, ratings of perceived exertion, and overall performance. However, limited research has investigated the differences between tempo-matched music and metronome pacing on running performance. Many runners utilize metronome pacing to pace a run, improve efficiency, and enhance form. To date, research on the efficacy of metronome pacing compared to music on one mile run time to completion is limited. PURPOSE: To determine the effects of different auditory stimuli (e.g., music, metronome, and silence) on one mile run time in young adults. METHODS: Young …

Differences In Children’S Food And Beverage Consumption Between School And Summer: Three-Year Findings From The What’S Up (Undermining Prevention) With Summer Observational Cohort Study, Michael Beets Med, Mph, Phd, Sarah Burkart, Christopher D. Pfledderer, Elizabeth L. Adams Phd, Robert Weaver Med, Phd, Bridget Armstrong, Keith Brazendale, Xuanxuan Zhu, Alexander Mclain, Gabrielle Turner-Mcgrievy Ph.D., Rd, Russell R. Pate, Andrew T. Kaczynski, Amanda Fairchild, Brian Saelens, Hannah Parker, Amy L. Yaroch, Emily Eglitis, Anthony J. Holmes

Faculty Publications

Background

Summer vacation is a time when youth gain excessive weight. A key driver of unhealthy weight gain is poor dietary quality. The absence of consistent structure (e.g., school), is hypothesized to be one of the reasons for lower diet quality during summer. This study examined differences in school and summer dietary quality among a diverse cohort of children across three years. We also examined the impact of attending structured programs on children’s diets.

Methods

Parents of 1,032 children (age 5–14 years, 48% girls) completed a time use diary each day for 14-days during school (April/May) and again in summer …

Acute Effect Of A Multi-Ingredient Pre-Workout Supplement On Pacing And Kinetic Expression During Shorter And Longer Bouts Of High Intensity Functional Training, Gerald Mangine, Christopher Staples, James W. Henley, Ashley Hines, Kristyn C. Mcgeehan, Wysmark Chaves, Wil King, Tiffany A. Esmat, John R. Mclester, Jacob L. Grazer

Faculty Articles

Background: High-intensity functional training (HIFT) varies daily workout programming, and trainees are often tasked with completing “as many repetitions as possible” (AMRAP) within a set time. Successful performance depends on fatigue management skills and maintaining a consistent expression of force and velocity when performing and transitioning between exercises over the duration of the workout. Multi-ingredient preworkout (MIPS) supplement formulations often contain ingredients shown to facilitate energy availability and mitigate fatigue, and therefore, might positively affect HIFT performance. This study aimed to assess a multi-ingredient pre-workout supplement’s acute effect on pacing and the expression of kinetics throughout a 5- and 15-minute …

Blood Flow Occlusion Superimposed On Low-Volume, Low-Intensity Knee Extensions Does Not Evoke Hypoalgesia: A Pilot Study, Sophie-Jayne Morgan, Jenny Zhang, Neil Lemay, Neda Khaledi, Saied J. Aboodarda

Topics in Exercise Science and Kinesiology

Topics in Exercise Science and Kinesiology Volume 6: Issue 1, Article 9, 2025. Exercise-induced hypoalgesia (EIH) is a transient decrease in pain perception that can be observed following various tasks, including low-intensity and high-intensity exercise. The application of blood flow occlusion (BFO) can help enhance exercise adaptations while being able to exercise at a low intensity, which has important implications for clinical and rehabilitative settings. Through descending inhibitory pathways, BFO-induced pain can potentially alleviate exercise-induced pain. This study aimed to assess whether the superimposition of BFO – and its associated augmented perceived responses – during low-intensity, low-volume resistance exercise could …

A Comparison Of Measured Versus Estimated Metabolic Equivalents (Mets) During The Farmer's Carry And Sled Push Exercises On A Commercially Available Step Mill, Colin Miller, Ethan Remotigue, Shane Hammer, J. Jay Dawes, Taylor K. Dinyer-Mcneely

Topics in Exercise Science and Kinesiology

Topics in Exercise Science and Kinesiology Volume 6: Issue 1, Article 8, 2025. The Stairmaster 10G ergometer allows users to perform non-traditional movements such as the sled push and farmer’s carry, which involve substantial upper and lower body contributions. Standard MET calculations for stair stepping do not account for this increase upper-body workload, so there is potential for error when aiming to determine exercise intensity based exclusively on estimated METs. The primary purpose of this study is to compare the metabolic and physiological effects of two training modes on the Stairmaster 10G ergometer, specifically evaluating the accuracy of MET values …

Effectiveness Of A Telephone-Delivered Walk With Ease Program On Arthritis-Related Symptoms, Function, And Activity: A Randomized Trial, Christine Pellegrini Ph.D., Sara Wilcox Phd, Yesil Kim, Scott Jamieson, Katherine Devivo, Daniel Heidtke

Faculty Publications

Objective

Walk With Ease (WWE) is a six-week arthritis-appropriate evidence-based physical activity program traditionally offered in a face-to-face format. Because many populations encounter participation barriers to in-person programs, WWE was modified for telephone delivery (WWE-T). The short- and long-term effects of this program on physical activity and arthritis-related outcomes were examined.

Methods

Participants (n = 267) with arthritis were randomized to WWE-T or a wait list control. WWE-T participants received two telephone calls per week (one group and one individual call) for six weeks. Group calls focused on arthritis education and social support. Individual calls focused on problem-solving and goal …

Novel Approaches To Combat Neuro-Degradation: Investigations Of Two Supplemental Strategies Aimed At Improving Warfighter Performance, Blaine Lints

Theses and Dissertations

This dissertation examines the efficacy of two distinct nutritional supplementation strategies for improving physical and/or cognitive performance under stress. The first study investigated the effects of 150 mg caffeine plus 150 mg theacrine ingestion in tactically trained individuals. Results indicated that the combination of caffeine and theacrine was associated with significant improvements in reaction time, accuracy, and measures of ocular control following high-intensity interval (HII) exercise. The HII exercise protocol consisted of ten repetitions of 60s high-intensity intervals (≥90% maximal oxygen uptake [VO_2max]) followed by 120s low-intensity intervals (~40% VO_2max) on a treadmill. These benefits were …

Investigating Mechanisms And Day-Level Factors That Influence Children’S 24-Hour Movement Behaviors, Hannah Parker

Theses and Dissertations

Twenty-four hour movement behaviors (i.e., physical activity (PA), screen time (ST), and sleep) are associated with health outcomes, chronic disease (obesity, type 2 diabetes), and mortality. Most literature evaluating children’s 24-hour movement behaviors has focused on static person-level demographic information such as age or biological sex. Relatively less work has examined the variable factors that change day to day, such as environment or context. The Structured Days Hypothesis (SDH) suggests that when children are in structured environments, they have healthier movement behaviors compared to less structured environments where children have more discretionary time to engage in obesogenic behaviors. Besides school/childcare, …

Modeling The Interaction Between Pain And Movement: Insights From Brain Activation Patterns And Context-Dependent Emotion In Chronic Low Back Pain, Pradeep Kumar Sahu

Theses and Dissertations

In persons with chronic pain, fear or anxiety related to movement is a well-established model under the biopsychosocial framework that explains in part, the chronicity of symptoms commonly reported by individuals with chronic low back pain (cLBP). This dissertation aimed to further understand the link between the context-dependent emotion network in the brain and movement in two separate studies using brain functional MRI and autonomic nervous system indices. Aim 1sought to investigate the brain functional connectivity linking brain regions involved in context-dependent emotion and movement while cLBP participants moved their back inside the scanner by performing a modified trunk bridging …

Academic Wellness In Health Professional Students: The Intersection Between Dietary Attitudes And Behaviors, Sleep Quality, And Mental Health, Kenya Shereece Moore

Theses and Dissertations

Academic success is strongly influenced by student well-being, with nutrition, sleep, and mental health emerging as critical and interconnected components. Health profession students often face significant mental and physical demands, as they navigate their educational training, which can challenge their ability to maintain healthy behaviors and access necessary support. Although these students are often trained to recognize, treat, and promote wellness in others, they may struggle to prioritize or seek care for themselves. This work aims to explore the health behaviors and care-seeking patterns of health profession students, with a focus on dietary habits, sleep, and barriers to mental health …

Establishing A Novel Neurofunctional Pre-Season Baseline For Sports-Related Concussion In Men And Women Collegiate Athletics, Jonathan C. Vincent, Jon G. Divine Md Ms, Aaron Kuehn-Himmler At Ms, Robert E. Mangine Pt Med Atc, Jim K. Ellis Od, Frederick R. Carrick Dc, Phd, Ms-Hped, Kimberly A. Hasselfeld, Blake M. Bacevich, Daniel Fosselman Do Mba, Joseph F. Clark Phd, Atc

Journal for Sports Neuroscience

Objective: To develop and validate a multi-domain neurofunctional baseline incorporating ocular, vestibular, proprioceptive, and cognitive assessments for collegiate athletes, thereby providing a more comprehensive approach to detecting and managing sports-related concussions.

Design: Retrospective chart review of pre-season baseline data.

Setting: Collegiate athletic training facility.

Participants: A total of 194 Division I collegiate athletes aged 18–24 years, stratified by sport, sex, and self-reported concussion history.

Interventions: A comprehensive battery of clinical and instrument-based neurological assessments, including Dynavision D2 tests (visual-motor coordination and reaction time), stereopsis, convergence, proprioception, peripheral vision, and retinal nerve fiber layer (RNFL) thickness measurements.

Main Outcome Measures: Normative …

Sensory Integration Processes Characterize Concussed Athletes With Balance Deficits, Bhagyashree Singh, Ingo Helmich

Exercise and Sport Studies: Faculty Publications

Impaired postural control constitutes a major symptom after mild traumatic brain injuries (mTBI/sport-related concussions (SRC)). In order to uphold cognition and behavior during pathological situations, individuals may be characterized by neuronal upregulation. Because postural control necessitates the integration of sensory information within somatosensory (/parietal) cortices, we investigated the hypothesis that athletes with ongoing symptoms after SRC are characterized by increased brain activation within these areas in order to compensate for postural deficits. Sixty-six athletes (27 ± 13 years; 50 men, 16 women) participated in the study. Twenty-two concussed athletes reported high post-concussion symptoms (PCS; symptomatic group), and 22 concussed athletes …

Global Mitophagy Inhibition Via Bnip3 Ablation Is Not Sufficient To Alleviate Skeletal Muscle Impairments In Male And Female Tumor-Bearing Mice, Francielly Morena, Ana Regina Cabrera, Toby L. Chambers, Pietier J. Koopmans, Seongkyun Lim, Stavroula Tsitanou, Sabin Khadgi, Calvin Peterson, Eleanor R. Schrems, Ruqaiza Muhyudin, Sepideh Shakeri, Kevin Zhao, Devan Mishra, Tyrone Washington, Kevin A. Murach, Nicholas P. Greene

Health, Human Performance and Recreation Faculty Publications and Presentations

Cancer cachexia (CC) is marked by severe skeletal muscle loss and dysfunction, associated with mitochondrial degeneration. Our previous studies showed induction of the mitophagy marker BNIP3 3-wk post-Lewis lung carcinoma (LLC) induction. We hypothesize that excessive mitophagy contributes to muscle wasting in CC. To test this, we used a Bnip3 knockout (KO) mouse model with LLC-induced CC to assess its impact on muscle outcomes. Eight-wk-old male and female mice were injected with 1 x 10(6) LLC cells or PBS (sham controls). After 4 wk, we assessed muscle function through dorsiflexor electrophysiology, muscle protein synthesis via deuterium oxide labeling, and mitochondrial …

The N-Pact Factor, Replication And Power Associated With Quantitative Research In Physical Activity And Health, Angelina Haidar, Jeffrey J. Martin, Adam J. Martin, Sarah Rogers, Fatemeh Dehghan, Eva Prokesova

International Journal of Physical Activity and Health

Physical Activity (PA) and health science researchers often face challenges related to sample size, which can impact the reliability and generalizability of study findings. The purpose of the current paper is to address these issues by discussing key statistical concepts: effect size and Type I and Type II errors, with a specific focus on examining statistical power and sample size using studies from the Disability and Health Journal (DHJ). We examined research articles published in DHJ over a 15-year period (2008–2022), covering 62 issues and analyzing a total of 1,177 articles. Our analysis revealed that the median sample sizes …

Associations Between 24-Hour Movement Compositions And Cardiometabolic Health In Children And Adolescents: A Five-Part Compositional Analysis Using Data From The International Children’S Accelerometery Database (Icad), Zoë A. Marshall, Adam Runacres, Pedro Curi Hallal, Russ Jago, Soyang Kwon, Kate Northstone, Russell R. Pate, Jardena Puder, John J. Reilly, Luis B. Sardinha, Niels Wedderkopp, Ester Van Slujis

Faculty Publications

Objectives The benefits of physical activity (PA) and the negative impacts of sedentary time (SED) on health in youth are well established. However, uncertainty remains surrounding how PA and SED jointly influence cardiometabolic risk (CMR) factors. The aim of this study was to determine the joint influence of SED, light-, moderate- and vigorous-intensity PA (LPA, MPA and VPA), and sleep on CMR factors using five-part compositional analyses.

Methods Data were pooled from 16 cohort studies comprising 22 474 children and adolescents from the International Children’s Accelerometery Database. PA was measured using hip-mounted accelerometers with sleep self-reported. CMRs included body mass …