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Articles 61 - 90 of 304

Full-Text Articles in Medicine and Health

Addressing The Black Maternal Mortality Rate, Kennedy Sanders, Venkateswar Venkataraman, Kate Whelihan May 2024

Addressing The Black Maternal Mortality Rate, Kennedy Sanders, Venkateswar Venkataraman, Kate Whelihan

Rowan-Virtua Research Day

Introduction: As of 2021, the Black maternal mortality rate in the United States was 69.9 deaths per 100,000 live births as compared to the national average of 32.9 and the White American average of 26.61. It has been demonstrated that this discrepancy is not fully explained by socioeconomic status. Doulas are professionals who provide support and guidance throughout pregnancy, birth, and early parenthood. Encouraging the use of doulas may be an effective approach to improve the birth experience for Black mothers. Methods: A literature review was performed using PubMed and the following search strings: maternal mortality rate (+race, +race +ethnicity, …


The Importance Of Framing The Context Of Black/African Americans' Livelihood To Enhance Health Outcomes And Mitigate Health Inequalities, Elvis Gyan May 2024

The Importance Of Framing The Context Of Black/African Americans' Livelihood To Enhance Health Outcomes And Mitigate Health Inequalities, Elvis Gyan

Theses, Dissertations and Culminating Projects

This study investigates the portrayal of Black/African Americans in Health Marriage and Relationship Education (HMRE) programs, which predominantly follow Eurocentric models while examining how social and structural determinants (e.g., community context) influence stress levels, general health, and relationship satisfaction through two main objectives. Firstly, it aims to scrutinize the acknowledgment of biases towards non-Eurocentric communities in published Administration of Children and Families HMRE programs, analyzing 39 research studies. Secondly, it examines the interplay between perceived community context, stress as a mediator, general health, and relationship satisfaction among Black/African Americans across three distinct articles by testing hypothesized process models. Results for …


Trends In Sleep Duration In The Us From 2004 To 2018: A Decomposition Analysis, Jiahui Xu, Liying Luo, Alyssa Gamaldo, Ashton Verdery, Melissa Hardy, Orfeu M Buxton, Qian Xiao Mar 2024

Trends In Sleep Duration In The Us From 2004 To 2018: A Decomposition Analysis, Jiahui Xu, Liying Luo, Alyssa Gamaldo, Ashton Verdery, Melissa Hardy, Orfeu M Buxton, Qian Xiao

Faculty, Staff and Student Publications

Average sleep duration in the United States declined in recent years, and the decline may be linked with many biopsychosocial factors. We examine how a set of biopsychosocial factors have differentially contributed to the temporal trends in self-reported sleep duration across racial groups between 2004-2005 and 2017-2018. Using repeated nationally representative cross-sections from the National Health Interview Survey, we decompose the influence of biopsychosocial factors on sleep duration trends into two components. One component corresponds to coefficient changes (i.e., changes in the associations between behaviors or exposures and sleep duration) of key biopsychosocial factors, and the other part accounts for …


Cultura Y (Ataque De) Corazón: A Training For Health Professionals Needing Medical Interpretation Services, Elizabeth Dudek, Shelby Edwards Feb 2024

Cultura Y (Ataque De) Corazón: A Training For Health Professionals Needing Medical Interpretation Services, Elizabeth Dudek, Shelby Edwards

11th National Symposium on Spanish as a Heritage Language (Archived)

Limited English proficiency is a known barrier to quality health care outcomes (Green 2017, Helmi 2021). Inclusion of a certified language interpreter during health care encounters improves outcomes among ESL (English as a Second Language) patients (Karliner, Jacobs, Chen, and Mutha 2007). Interpretation with a certified interpreter promotes understanding between patients and their medical providers, and advances both health and race equity (Foiles Sifuentes, Robledo Cornejo, Castaneda-Avila, Tija, and Lapane 2020). Most health care workers receive no formal training in how to use an interpreter with limited English-proficiency patients. Located in the Hispanic Heritage District of an increasingly Latine mid-sized …


Non-Fatal Intimate Partner Violence In Seminole County, Fl, 2016-2020, Jonzelle Bell Bs, Julio Montanez Ma, Amy Donley Phd Feb 2024

Non-Fatal Intimate Partner Violence In Seminole County, Fl, 2016-2020, Jonzelle Bell Bs, Julio Montanez Ma, Amy Donley Phd

Institute for Social and Behavioral Science (ISBS)

In 2024, the University of Central Florida's Institute for Social and Behavioral Science developed a white paper summarizing Uniform Crime Reports data for Seminole County, FL from the Florida Department of Law Enforcement. The white paper tabulates intimate partner violence offenses by victim-offender relationship, offense severity, and offense type.


Facilitators To Cervical Cancer Screening In A Minority, Urban, Underserved Population, Noel Higgason, Linh Nguyen, Yen-Chi Le, Ogochukwu Juliet Ezeigwe, Tong Han Chung, Natalia Williams, Xochitl K Olguin, Abigail S Zamorano Feb 2024

Facilitators To Cervical Cancer Screening In A Minority, Urban, Underserved Population, Noel Higgason, Linh Nguyen, Yen-Chi Le, Ogochukwu Juliet Ezeigwe, Tong Han Chung, Natalia Williams, Xochitl K Olguin, Abigail S Zamorano

Faculty, Staff and Student Publications

OBJECTIVES: Cervical cancer has markedly declined due to widespread use of screening, but Hispanic women continue to bear a disproportionate amount of the cervical cancer burden due to under-screening. Previous studies have explored barriers to screening but have failed to identify targetable facilitators in this group. We aimed to assess facilitators to cervical cancer screening among a predominantly urban, Hispanic population who presented to a no-cost, community-based clinic.

METHODS: Patients completed demographic and health information, a validated social determinants of health (SDOH) screen, and a self-reported facilitators survey on factors which enabled them to present to clinic. Descriptive statistics were …


Human Zoo Healthcare At The 1904 World’S Fair, Angel Blake Jan 2024

Human Zoo Healthcare At The 1904 World’S Fair, Angel Blake

Undergraduate Research Symposium

Human Zoo Healthcare at the 1904 World’s Fair

Were precautions taken or put into place for the Human Zoo performers at the 1904 World’s Fair? This topic has been overlooked and understudied by historians, there are few articles written and we do not know the true death toll which shows the racism towards these indigenous peoples. The research for this project was conducted at the State Historical Society of Missouri, the St. Louis Mercantile Library, Newspapers.com, Archives.com, St. Louis Public Library, and the Missouri Historical Society, including research on primary sources such as official World’s Fair committee meeting minutes, hospital …


Perceived Neighborhood Disorder And Type 2 Diabetes Disparities In Hispanic, Black, And White Americans, Min Ying Yu, Alfredo J. Velasquez, Belinda Campos, Jennifer W. Robinette Jan 2024

Perceived Neighborhood Disorder And Type 2 Diabetes Disparities In Hispanic, Black, And White Americans, Min Ying Yu, Alfredo J. Velasquez, Belinda Campos, Jennifer W. Robinette

Psychology Faculty Articles and Research

Introduction: Approximately 32 million Americans have type 2 diabetes, and that number continues to grow. Higher prevalence rates are observed among certain subgroups, including members of marginalized racial/ethnic groups as well as residents of disordered neighborhoods (i.e., those with more trash and vandalism). Institutionalized discriminatory practices have resulted in disproportionate representation of marginalized racial/ethnic groups in disordered neighborhoods compared to non-Hispanic Whites. These neighborhood disparities may partially contribute to health disparities, given that signs of neighborhood disorder often relate to a general withdrawal from the neighborhood, minimizing opportunities for both physical and social engagement. Yet, research suggests variability across …


Outpatient Fall Prevention In Ambulatory Adults 65 Years Old And Over, Dorothy L. Osborne-White Jan 2024

Outpatient Fall Prevention In Ambulatory Adults 65 Years Old And Over, Dorothy L. Osborne-White

Doctor of Nursing Practice (DNP) Scholarly Projects - Archive

Background: In the United States (U.S.), falls are the leading cause of injury among adults 65 and over, resulting in 36 million falls yearly (Moreland et al., 2020). According to the Centers for Disease Control and Prevention (CDC, 2023), one in four older adults experiences a fall each year. Falls are the world's second most prominent cause of accidental deaths (World Health Organization [WHO], 2021). Falls are the leading cause of both fatal and non-fatal injuries among older adults (Moreland et al., 2020).

Methods: A quality improvement project that included a fall bundle was implemented in a primary clinic. A …


Implementing Social Determinants Of Health Data Collection In A Large Urban Pediatric Hospital Setting, Stormee Williams, Kristina Hill, Barry Owen, Forest Melton Jan 2024

Implementing Social Determinants Of Health Data Collection In A Large Urban Pediatric Hospital Setting, Stormee Williams, Kristina Hill, Barry Owen, Forest Melton

Research

No abstract provided.


Autopathography Across Media: Trauma And Fluid Embodied Subjectivity, He (Kristen) Shen Jan 2024

Autopathography Across Media: Trauma And Fluid Embodied Subjectivity, He (Kristen) Shen

Honors Theses

Illness memoirs with first-person point of view have gained more attention in recent years among medical sociologists and anthropologists. Different from traditional “case histories”written by doctors that are in danger of ignoring patients’ voices, autopathograhical works delineate narrators’ transformative experiences of persons to patients, emphasizing the importance of gaining social understanding of illness. Focusing on three works within the category of autopathography across genres and media forms in the late 1950s and contemporary periods, The Cancer Journals (1980) written by Audre Lorde, The Collected Schizophrenias (2019) written by Esmé Weijun Wang, and The Diving Bell and the Butterfly (2007) directed …


Health Consequences Of Racial Disparity In Access To Abortion: A Systematic Review, Lacy M. Frye, Calvin Odhiambo Jan 2024

Health Consequences Of Racial Disparity In Access To Abortion: A Systematic Review, Lacy M. Frye, Calvin Odhiambo

University of South Carolina Upstate Student Research Journal

Prior to the 2022 Dobbs decision, Black women already experienced negative maternal health outcomes at an alarmingly disparate rate in comparison to White women. Given that the Dobbs decision emboldens state power to enforce abortion restrictions or protections, there has been significant strides made in both directions. Nonetheless, within states where reproductive rights have been significantly eroded, the heightened abortion restrictions may compound the limited access that Black women previously had before Dobbs. This, in turn will exacerbate the already disparate negative maternal outcomes that Black women experience. However, research on the relationship between the lack of access to abortion …


The Unequal Distribution Of Social Risk For Black Men Across The Life-Span. A Novel Framework., Waleed Y. Sami Jan 2024

The Unequal Distribution Of Social Risk For Black Men Across The Life-Span. A Novel Framework., Waleed Y. Sami

Adultspan Journal

This conceptual overview offers a comprehensive overview of systemic pathways that negatively impact the mental health of Black Men throughout their lives. Our argument highlights the importance for counselors and mental health professionals to utilize a thorough social risk assessment that considers these pathways in order to effectively address the mental health needs of Black Men while fostering positive working relationships. This overview strongly advocates for the use of context and structural determinants when evaluating mental health symptoms. Without an appropriate understanding of social risk and determinants, counselors may inadvertently perpetuate disparities by decontextualizing symptomology, and reproducing racist discourse.


Determining The Differences Of Racial Microaggressions Faced By Multiracial Versus Monoracial Minority Patients Within Healthcare Settings, Elizabeth S. Ommi Jan 2024

Determining The Differences Of Racial Microaggressions Faced By Multiracial Versus Monoracial Minority Patients Within Healthcare Settings, Elizabeth S. Ommi

Honors Undergraduate Theses

This study examines the disadvantages that multiracial patients face when seeking healthcare in the United States in comparison to the disadvantages encountered by monoracial minority patients. Specifically, this study mainly focuses on the impacts of racial microaggressions within such medical settings. This was explored using a critical discourse analysis, analyzing discourse presented from past research published from 2014 to 2023. Discourse was collected based on its relevancy to the given topic and was analyzed to identify general disadvantages presented for each subpopulation. It was found that multiracial patients face different disadvantages when receiving medical care in comparison to monoracial minority …


Representation In Healthcare Matters: Perspectives On Inadequate Physician Diversity And Its Potential Impact On Minority Patients, Madison Andrews Jan 2024

Representation In Healthcare Matters: Perspectives On Inadequate Physician Diversity And Its Potential Impact On Minority Patients, Madison Andrews

Sociology Honors Papers

Disparities in access to healthcare among U.S. racial and ethnic groups, including access to quality services, have existed for centuries (Gibbons, 2005), leading to inequality in health outcomes as race/ethnicity intersects with gender and socioeconomic status (Wellons et al., 2009; Yan et al., 2023). Patients from minority communities face disadvantages due to the lack of diversity amongst physicians, including communication barriers, lack of trust, lesser rapport, and lower level of comfort with doctors who are non-representative of patients’ demographics (Ha & Longnecker, 2010; Lopez et al., 2023; Maldonado et al., 2014; Weech-Maldonado et al., 2003). It is important, then, to …


Association Of Social Vulnerability And Covid-19 Mortality Rates In Texas Between 15 March 2020, And 21 July 2022: An Ecological Analysis, Dennis Ogeto Nyachoti, Nalini Ranjit, Ryan Ramphul, Leah D Whigham, Andrew E Springer Oct 2023

Association Of Social Vulnerability And Covid-19 Mortality Rates In Texas Between 15 March 2020, And 21 July 2022: An Ecological Analysis, Dennis Ogeto Nyachoti, Nalini Ranjit, Ryan Ramphul, Leah D Whigham, Andrew E Springer

Faculty, Staff and Student Publications

BACKGROUND: Despite the key role of social vulnerability such as economic disadvantage in health outcomes, research is limited on the impact of social vulnerabilities on COVID-19-related deaths, especially at the state and county level in the USA.

METHODS: We conducted a cross-sectional ecologic analysis of COVID-19 mortality by the county-level Minority Health Social Vulnerability Index (MH SVI) and each of its components in Texas. Negative binomial regression (NBR) analyses were used to estimate the association between the composite MH SVI (and its components) and COVID-19 mortality.

RESULTS: A 0.1-unit increase in the overall MH SVI (IRR, 1.27; 95% CI, 1.04-1.55; …


Analyzing African American College Student Willingness To Participate In Clinical Trials, Caitlin B. Ulmer Oct 2023

Analyzing African American College Student Willingness To Participate In Clinical Trials, Caitlin B. Ulmer

Senior Theses

Previous studies regarding African American participation in clinical trials have found that African Americans participate at a significantly lower rate than other ethnic/racial groups. Scholars argue that this lack of participation in clinical trials is a direct result of historical trauma linked to unethical experiments and African American distrust in the healthcare system. However, there is a gap in the literature because these studies focus on African American individuals above the age of 30. This study aimed to fill the gap by examining clinical trial participation among African American college students within the ages 18 to 23. This study also …


Colonial Geographies Of Gendered Violence And Mental Health In The United States And Puerto Rico, Lorraine Lizbeth L. Torres Colon Sep 2023

Colonial Geographies Of Gendered Violence And Mental Health In The United States And Puerto Rico, Lorraine Lizbeth L. Torres Colon

Dissertations, Theses, and Capstone Projects

As of January 2021, after years of community organizing and protests, the Puerto Rican island government announced a state of emergency due to the high rates of gendered violence on the island. At the same time, within the field of psychiatric epidemiology, consistent findings have indicated higher frequencies of mood disorders and substance abuse disorders among Puerto Ricans both on and off the island, relative to all other US Latinx ethnic groups. This dissertation frames Puerto Ricans experiences with psychological distress and gendered violence as public health issues nested within differing geographies of colonial divestment. I explore the relationships between …


Confronting The Doppelganger: Mapping The Ontological Terrain Of An Afro-Caribbean Woman As She Rebrands Diasporic, Feminine Identity Politics: An Autoethnography, Aysha E. Todd-Stone Sep 2023

Confronting The Doppelganger: Mapping The Ontological Terrain Of An Afro-Caribbean Woman As She Rebrands Diasporic, Feminine Identity Politics: An Autoethnography, Aysha E. Todd-Stone

Dissertations, Theses, and Capstone Projects

This thesis seeks to interrogate the intricacies governing the intra-racial\ intra-gendered relationship of an Afro-Trinidadian woman as she commandeers professional spaces in North America. The intent is to challenge the instrument of Black sisterhood deeming it as an incomplete, social instrument, and to prove using an auto-ethnographic approach how Diasporic, feminine trauma leads to psychically induced, episodic violence that is highly suggestive but subtle to the naked eye which in turn irretrievably damages intra-interpersonal relations. Quantitative studies have produced a composite from the white\black perspective (Goosby et al., 2015, Sims et al., 2012) and others dealing with gender (Braithwaite., 1981, …


A Polygenic Risk Score For Alzheimer’S Disease Constructed Using Apoe-Region Variants Has Stronger Association Than Apoe Alleles With Mild Cognitive Impairment In Hispanic/Latino Adults In The Us, Tamar Sofer, Nuzulul Kurniansyah, Einat Granot-Hershkovitz, Matthew O Goodman, Wassim Tarraf, Iris Broce, Richard B Lipton, Martha Daviglus, Melissa Lamar, Sylvia Wassertheil-Smoller, Jianwen Cai, Charles S Decarli, Hector M Gonzalez, Myriam Fornage Aug 2023

A Polygenic Risk Score For Alzheimer’S Disease Constructed Using Apoe-Region Variants Has Stronger Association Than Apoe Alleles With Mild Cognitive Impairment In Hispanic/Latino Adults In The Us, Tamar Sofer, Nuzulul Kurniansyah, Einat Granot-Hershkovitz, Matthew O Goodman, Wassim Tarraf, Iris Broce, Richard B Lipton, Martha Daviglus, Melissa Lamar, Sylvia Wassertheil-Smoller, Jianwen Cai, Charles S Decarli, Hector M Gonzalez, Myriam Fornage

Faculty, Staff and Student Publications

INTRODUCTION: Polygenic Risk Scores (PRSs) are summaries of genetic risk alleles for an outcome.

METHODS: We used summary statistics from five GWASs of AD to construct PRSs in 4,189 diverse Hispanics/Latinos (mean age 63 years) from the Study of Latinos-Investigation of Neurocognitive Aging (SOL-INCA). We assessed the PRS associations with MCI in the combined set of people and in diverse subgroups, and when including and excluding the APOE gene region. We also assessed PRS associations with MCI in an independent dataset from the Mass General Brigham Biobank.

RESULTS: A simple sum of 5 PRSs ("PRSsum"), each constructed based on a …


An Sms Text Message-Based Type 2 Diabetes Prevention Program For Hispanic Adolescents With Obesity: Qualitative Co-Design Process, Erica Soltero, Callie Lopez, Sandra Mihail, Ayleen Hernandez, Salma M Musaad, Teresia M O'Connor, Debbe Thompson Aug 2023

An Sms Text Message-Based Type 2 Diabetes Prevention Program For Hispanic Adolescents With Obesity: Qualitative Co-Design Process, Erica Soltero, Callie Lopez, Sandra Mihail, Ayleen Hernandez, Salma M Musaad, Teresia M O'Connor, Debbe Thompson

Faculty, Staff and Students Publications

BACKGROUND: SMS text message-based interventions are a promising approach for reaching and engaging high-risk youths, such as Hispanic adolescents with obesity, in health promotion and disease prevention opportunities. This is particularly relevant, given that SMS text messaging is widely accessible and available and that adolescents are frequent texters. Including youths in the development of SMS text message content can lead to more acceptable and relevant messaging; however, few studies include this group as cocollaborators.

OBJECTIVE: This study aimed to use a co-design process to inform the development of SMS text messages that promote healthy physical activity (PA) and sleep behaviors …


Unintentional Fatal Overdose Analysis In Orange County, Fl Yearly Trends 2018-2022, Alexandria Mcclarty, Amy Donley Phd Jul 2023

Unintentional Fatal Overdose Analysis In Orange County, Fl Yearly Trends 2018-2022, Alexandria Mcclarty, Amy Donley Phd

Institute for Social and Behavioral Science (ISBS)

This report aims to analyze yearly trends in unintentional fatal overdoses in Orange County, FL. Like many other parts of the country, the Central Florida area continues to suffer from a high number of overdose mortalities. As such, this report analyzes unintentional fatal overdoses across the years 2018-2022, focusing on the variables of sex, race, age, drug toxicology, victim residency information, and death location to draw conclusions on Orange County’s overdose climate and identify any changes over time. Additionally, we analyze quarterly trends within each calendar year, and estimate overdose rates in regard to county population by using publicly available …


Does Using Sofa Score For Ventilator Triage Among Covid 19 Patients Result In Suboptimal Allocation Of Medical Ventilators For The Bipoc Population?, Alexandrea Mp Masocco, Elisabeth Michel, Ebbin Dotson Jul 2023

Does Using Sofa Score For Ventilator Triage Among Covid 19 Patients Result In Suboptimal Allocation Of Medical Ventilators For The Bipoc Population?, Alexandrea Mp Masocco, Elisabeth Michel, Ebbin Dotson

Journal of Health Disparities Research and Practice

Introduction: Since the COVID-19 pandemic in the United States, Black, and Latinx populations have been disproportionately affected by the COVID-19 pandemic. It can be inferred with high confidence that those most vulnerable are the least likely to receive essential care. Kidney transplant allocation and COVID-19 triage protocols share commonalities in that both protocols involve using multivariate scored criteria with objective and subjective inputs. As such, the similar conclusion in outcomes is concerning. It is worth questioning whether the racial inequalities demonstrated in the COVID-19 pandemic related to access to life-saving ventilators were associated with triage protocols.

Methodology: Using an exploratory …


Assessment Of Personal Care Product Use And Perceptions Of Use In A Sample Of Us Adults Affiliated With A University In The Northeast, Adana A. M. Llanos, Amber Rockson, Kylie Getz, Patricia Greenberg, Eva Portillo, James A. Mcdonald, Dede K. Teteh, Justin Villasenor, Carolina Lozada, Jamirra Franklin, Vaishnavi More, Zorimar Rivera-Núñez, Carolyn W. Kinkade, Emily S. Barrett Jul 2023

Assessment Of Personal Care Product Use And Perceptions Of Use In A Sample Of Us Adults Affiliated With A University In The Northeast, Adana A. M. Llanos, Amber Rockson, Kylie Getz, Patricia Greenberg, Eva Portillo, James A. Mcdonald, Dede K. Teteh, Justin Villasenor, Carolina Lozada, Jamirra Franklin, Vaishnavi More, Zorimar Rivera-Núñez, Carolyn W. Kinkade, Emily S. Barrett

Health Sciences and Kinesiology Faculty Articles

Evidence supports unequal burdens of chemical exposures from personal care products (PCPs) among some groups, namely femme-identifying and racial and ethnic minorities. In this study, we implemented an online questionnaire to assess PCP purchasing and usage behaviors and perceptions of use among a sample of US adults recruited at a Northeastern university. We collected PCP use across seven product categories (hair, beauty, skincare, perfumes/colognes, feminine hygiene, oral care, other), and behaviors, attitudes, and perceptions of use and safety across sociodemographic factors to evaluate relationships between sociodemographic factors and the total number of products used within the prior 24–48 h using …


Neighborhood Disadvantage And Pediatric Inpatient Opioid Prescription Patterns, Ashley W. Kranjac, Dinko Kranjac, Zeev N. Kain, Louis Ehwerhemuepha, Candice Donaldson, Brooke N. Jenkins Jun 2023

Neighborhood Disadvantage And Pediatric Inpatient Opioid Prescription Patterns, Ashley W. Kranjac, Dinko Kranjac, Zeev N. Kain, Louis Ehwerhemuepha, Candice Donaldson, Brooke N. Jenkins

Sociology Faculty Articles and Research

Background

To explore the role of children's residential environment on opioid prescribing patterns in a predominantly Latinx sample.

Methods

We connected geocoded data from electronic medical records in a diverse sample of pediatric patients to neighborhood environments constructed using latent profile modeling techniques. We then estimated a series of multilevel models to determine whether opioid prescribing patterns vary by residential context.

Results

A stepwise pattern exists between neighborhood disadvantage and pediatric opioid prescription patterns, such that higher levels of disadvantage associate with a greater likelihood of opioid prescription, independent of the patient's individual profile.

Conclusion

In a largely Latinx sample …


Parabens Promote Protumorigenic Effects In Luminal Breast Cancer Cell Lines With Diverse Genetic Ancestry, Jazma L. Tapia, Jillian C. Mcdonough, Emily L. Cauble, Cesar G. Gonzalez, Dede K. Teteh, Lindsey S. Treviño Jun 2023

Parabens Promote Protumorigenic Effects In Luminal Breast Cancer Cell Lines With Diverse Genetic Ancestry, Jazma L. Tapia, Jillian C. Mcdonough, Emily L. Cauble, Cesar G. Gonzalez, Dede K. Teteh, Lindsey S. Treviño

Health Sciences and Kinesiology Faculty Articles

Context

One in 8 women will develop breast cancer in their lifetime. Yet, the burden of disease is greater in Black women. Black women have a 40% higher mortality rate than White women, and a higher incidence of breast cancer at age 40 and younger. While the underlying cause of this disparity is multifactorial, exposure to endocrine disrupting chemicals (EDCs) in hair and other personal care products has been associated with an increased risk of breast cancer. Parabens are known EDCs that are commonly used as preservatives in hair and other personal care products, and Black women are disproportionately exposed …


Evaluating The Use Of Blood Pressure Polygenic Risk Scores Across Race/Ethnic Background Groups, Nuzulul Kurniansyah, Matthew O Goodman, Alyna T Khan, Jiongming Wang, Elena Feofanova, Joshua C Bis, Kerri L Wiggins, Jennifer E Huffman, Tanika Kelly, Tali Elfassy, Xiuqing Guo, Walter Palmas, Henry J Lin, Shih-Jen Hwang, Yan Gao, Kendra Young, Gregory L Kinney, Jennifer A Smith, Bing Yu, Simin Liu, Sylvia Wassertheil-Smoller, Joann E Manson, Xiaofeng Zhu, Yii-Der Ida Chen, I-Te Lee, C Charles Gu, Donald M Lloyd-Jones, Sebastian Zöllner, Myriam Fornage, Charles Kooperberg, Adolfo Correa, Bruce M Psaty, Donna K Arnett, Carmen R Isasi, Stephen S Rich, Robert C Kaplan, Susan Redline, Braxton D Mitchell, Nora Franceschini, Daniel Levy, Jerome I Rotter, Alanna C Morrison, Tamar Sofer Jun 2023

Evaluating The Use Of Blood Pressure Polygenic Risk Scores Across Race/Ethnic Background Groups, Nuzulul Kurniansyah, Matthew O Goodman, Alyna T Khan, Jiongming Wang, Elena Feofanova, Joshua C Bis, Kerri L Wiggins, Jennifer E Huffman, Tanika Kelly, Tali Elfassy, Xiuqing Guo, Walter Palmas, Henry J Lin, Shih-Jen Hwang, Yan Gao, Kendra Young, Gregory L Kinney, Jennifer A Smith, Bing Yu, Simin Liu, Sylvia Wassertheil-Smoller, Joann E Manson, Xiaofeng Zhu, Yii-Der Ida Chen, I-Te Lee, C Charles Gu, Donald M Lloyd-Jones, Sebastian Zöllner, Myriam Fornage, Charles Kooperberg, Adolfo Correa, Bruce M Psaty, Donna K Arnett, Carmen R Isasi, Stephen S Rich, Robert C Kaplan, Susan Redline, Braxton D Mitchell, Nora Franceschini, Daniel Levy, Jerome I Rotter, Alanna C Morrison, Tamar Sofer

Faculty, Staff and Student Publications

We assess performance and limitations of polygenic risk scores (PRSs) for multiple blood pressure (BP) phenotypes in diverse population groups. We compare "clumping-and-thresholding" (PRSice2) and LD-based (LDPred2) methods to construct PRSs from each of multiple GWAS, as well as multi-PRS approaches that sum PRSs with and without weights, including PRS-CSx. We use datasets from the MGB Biobank, TOPMed study, UK biobank, and from All of Us to train, assess, and validate PRSs in groups defined by self-reported race/ethnic background (Asian, Black, Hispanic/Latino, and White). For both SBP and DBP, the PRS-CSx based PRS, constructed as a weighted sum of PRSs …


Strategies For Recruiting Underrepresented In Medicine And Sexual And Gender Minority Students To Emergency Medicine, Lauren T Wilson, Benjamin Weigel, Edgardo Ordonez, Navdeep Sekhon, Adedoyin Adesina, Anisha Turner, Aleksandr M Tichter, Sarah Bezek, Ynhi T Thomas Jun 2023

Strategies For Recruiting Underrepresented In Medicine And Sexual And Gender Minority Students To Emergency Medicine, Lauren T Wilson, Benjamin Weigel, Edgardo Ordonez, Navdeep Sekhon, Adedoyin Adesina, Anisha Turner, Aleksandr M Tichter, Sarah Bezek, Ynhi T Thomas

Faculty, Staff and Students Publications

BACKGROUND: Despite having well-described benefits, diversifying the physician workforce has been an ongoing challenge. Within emergency medicine (EM), multiple professional organizations have identified expanding diversity and inclusion as top priorities. The following is a description of an interactive session held at the SAEM annual meeting addressing recruitment strategies for underrepresented in medicine (URiM) and sexual and gender minority (SGM) students into EM.

METHODS: During the session, the authors provided an overview of the current state of diversity in EM. In the small-group portion of the session, a facilitator helped characterize the challenges programs face in recruiting URiM and SGM students. …


Analytical Approach For Monitoring The Behavior Of Patients With Pancreatic Adenocarcinoma At Different Stages As A Function Of Time, Aditya Chakaborty Dr, Chris P. Tsokos Dr May 2023

Analytical Approach For Monitoring The Behavior Of Patients With Pancreatic Adenocarcinoma At Different Stages As A Function Of Time, Aditya Chakaborty Dr, Chris P. Tsokos Dr

Biology and Medicine Through Mathematics Conference

No abstract provided.


Calculating Risk: A Scoping Review Of Ncaa D1 Football Players’ Motivations To Play And The Correlation To Demographic Characteristics And Injury Experiences, Kathleen D. Walsh May 2023

Calculating Risk: A Scoping Review Of Ncaa D1 Football Players’ Motivations To Play And The Correlation To Demographic Characteristics And Injury Experiences, Kathleen D. Walsh

Honors Theses

The purpose of this research was to investigate the motivations of National Collegiate Athletic Association (NCAA) Division 1 (D1) football players for playing the game and how these motivations are associated with their socioeconomic status (SES). Further, the research aimed to investigate how the uncovered motivations were linked to injury experiences. The original project was designed as a survey-based mixed methods study on a national scale. However, issues with participant recruitment led to sidelining of that primary research. The research presented is a scoping review of the available literature pertaining to the research question: What is known from existing literature …