Biological Psychology Commons^™

Anxiety-Like Behaviors And C-Fos Expression In Adult Zebrafish: Effects Of Housing Conditions, Alcohol And Caffeine, Adam Douglas Collier

Dissertations

Alcohol abuse is the third largest risk factor for disease world, responsible for an estimated 3.3 million deaths each year. The concomitant ingestion of alcohol and caffeine is hypothesized to increase risk factors associated with alcohol use alone by reducing subjective effects of intoxication. The zebrafish (Danio rerio) has recently garnered attention from researchers as an effective pre-clinical in-vivo animal model in behavioral pharmacology research, largely due to small size, low-cost and ease of drug delivery. A number of studies have reported the effects of alcohol and caffeine on zebrafish behavior at a variety of doses. However, the …

Humor In Medicine: A Literature Review Of Humor’S Potential Therapeutic Value In Health Care, Weston Michael Grant

Psychological Science Undergraduate Honors Theses

Using humor and laughter within the health care field has the potential to be relevant to patients during treatment, to the patient-caregiver relationship, to the subjective well-being of health care providers, and to the environments’ (e.g., work settings) impact on group relationships (e.g., colleagues). A review of the literature examines how the psychological and physiological effects of laughter and humor within the human body impact health and well-being, how humor and laughter improve the patient-practitioner relationship, and if humor and laughter can potentially impact physician burnout. Several possible implications for these findings are discussed, such as professional medical comedians, improvements …

The Influence Of Estrogen On Sex Differences In Chemotherapy-Induced Nausea And Vomiting (Cinv), Danna L. Zevy

Electronic Thesis and Dissertation Repository

Chemotherapy-induced nausea and vomiting (CINV) is one of the most distressing events that affects the quality of life of cancer patients. Evidence suggests that females are more susceptible to CINV than males, but the mechanism remains unknown. The current thesis examined whether higher levels of circulating estrogens in females contributes to this sex difference. CINV was analyzed in a pediatric oncology population, where it was revealed female patients demonstrate increased delayed CINV relative to male patients, in the post-pubertal age group. CINV was also studied by examining the influence of the estrous cycle on anticipatory nausea (AN) in rats. This …

Social Risks As Costly Trait Signals, Ruth E. Sarafin

Psychology ETDs

Costly signaling theory posits that people will sometimes engage in seemingly irrational behavior to show off attractive qualities about themselves. These behaviors may end in or incur a cost to the actor such that only individuals who are highly fit are able to succeed at the behavior, and therefore behavior success is an honest signal of fitness. Previous research has used costly signaling to explain human physical risk taking behaviors such as rock climbing, but the current study seeks to apply them to social risk taking, such as raising one’s hand in class. Should social risk taking prove to be …

Maternal Stress And Stress Symptomatology In Children, Emily Klipa

Undergraduate Distinction Papers

With stress being referred to as the “health epidemic of the 21^st century” by the World Health Organization, questions arise about not only how this epidemic affects adults, but also how stress may affect today’s children. Research indicates that stress impacting parents trickle down to children, and the effects can be palpable. In this study the author examined maternal stress as well as stress related symptoms and illnesses in their children. Participants are mothers of children age’s five to ten. The protocol included completion of a four part online survey addressing demographic information, perceived stress, and recent stressful life …

Image Memory For Hyperpalatable Foods In University Aged Females, Leila M. Mackay

Brescia Psychology Undergraduate Honours Theses

Hyperpalatable foods are high in sugar and/or fat and highly processed. These foods increase dopamine in the brain similar to other rewards, such as drugs of abuse, producing pleasure and an enhanced drive to consume them. Undergraduate students (n = 44) completed an explicit memory task where they were asked if they recalled various types of food (high sugar, high fat, sugar+fat, fruits, vegetables and breads) and non-food images. Questionnaires evaluating eating patterns were also completed. It was hypothesized that hyperpalatable foods would be recalled better and faster than less-palatable foods or non-food images. The study found that hyperpalatable …

Exploring Neural Entrainment And Beat Perception Through Movement, Sarah M. Schwanz

Brescia Psychology Undergraduate Honours Theses

The way humans move to music has a large impact on how music is synchronized to, interpreted, and enjoyed. It is understood that movements to music aid in beat perception, and neural oscillations have the ability to entrain to musical rhythms. This study attempted to link these two well-established phenomena by exploring the use of movement to simple and complex musical rhythms to enhance neural entrainment. Ten undergraduate students engaged in 60 simple and complex musical rhythms, either tapping along to the beat or listening without movement, while undergoing EEG recording. Although the differences in brain response amplitude were not …

Cognitive Functioning During Conflict In Intimate Partner Relationships Between Traumatized And Non-Traumatized Samples, Kylie N. Coleman

Doctor of Psychology (PsyD)

Significant differences have been found in neural connectivity of the brain in frontal, central, temporal, and parietal areas of individuals who experienced childhood trauma compared to those who had not (Cook, Ciorciari, Varker, & Devilly, 2009). This study investigated the relationship between the number of distressing and traumatic life experiences and participants’ neural responses to observing simulated conflict in intimate relationship. Graduate students (n = 11) answered conflict resolution and emotional activation questions while watching a simulated, escalating marital conflict. The participants’ neural responses were recorded via EEG mean power data from frontal and temporal brain regions. Heart rate (bpm) …

Dopamine D1 And D3 Receptor Polypharmacology In Cocaine Reward And Cocaine Seeking, Ewa J. Galaj

Dissertations, Theses, and Capstone Projects

Background: In the search for efficacious pharmacotherapies to treat cocaine addiction much attention has been given to agents targeting D1 or D3 receptors because of the involvement of these receptors in cocaine-related behaviors. D1 and D3 receptor partial agonists and antagonists have been shown to reduce cocaine reward, reinstatement of cocaine seeking and conditioned place preference (CPP) in rodents and non-human primates. However, translation of these encouraging results with selective D1 or D3 receptor agents has been limited due to a number of factors including toxicity, poor pharmacokinetic properties and extrapyramidal and sedative side effects.

Purpose: Given the …

Capturing The Attention Of Caregivers: Variability In Infant Vocalizations, Catharine A. Castelluccio De Diesbach

Dissertations, Theses, and Capstone Projects

The effect of variability in infant vocalizations on potential caregivers’ heart rate variability (HRV), facial expressions, and subjective ratings on emotional reactions and desire to approach the baby was examined in an evolutionary context. Recordings of non-canonical, canonical, fussing, and crying vocalizations were utilized to elicit physiological and self-reported reactions from sixty participants. Breastfeeding mothers, non-mothers at high estradiol point in menstrual cycle, non-mothers at low estradiol point in menstrual cycle, fathers, and non-fathers were included in the study. Participants wore Polar RS800 heart rate monitors, were video recorded for facial expression analysis, and filled out 11 point self-rating forms …

Sex Differences In The Anxiety Effects Of Cannabinoids, Helen T. French

Dissertations, Theses, and Capstone Projects

Aim: Anxiety disorders are twice as common among women, and those with anxiety disorders are 2-3 times more likely to have a substance abuse disorder than the general populace. However, little data exists on the sexually dimorphic effects of cannabinoids. In male humans and rodents, low acute doses of cannabinoids are anxiolytic while high and/or chronic doses are anxiogenic. In the dose response curve (DRC), we examined whether the biphasic effects of cannabinoids observed in males are also present in females. In the CB1R antagonism study, CP55,940-induced CB1R activation was antagonized via the CB1R-selective antagonist rimonabant to test the hypothesis …

Estradiol, Substance P, And The Pi3k-Akt-Mtor Pathway In The Dorsal Horn Of The Spinal Cord During Inflammatory Pain, Zane Ferguson

Dissertations, Theses, and Capstone Projects

Pain is a critical survival mechanism that signals potential or actual damage, but it can become pathological when it persists beyond the injury. Chronic pain is a major health issue that affects 10-20% of the adult population and is found disproportionately in women. There are numerous, interacting mechanisms underlying this phenomenon. This study used female rats to investigate the impact of estrogens on sensory signaling by substance P, a neuropeptide that contributes to the development of chronic pain, and the PI3K-Akt-mTOR pathway, an intracellular mechanism of nervous system plasticity.

Bitter Taste Preference And Psychopathy: A Partial Replication Of Sagioglou And Greitemeyer, 2016, Lauren A. Waymire

Honors Program Theses

In this study, we did a partial replication of Sagioglou and Greitemeyer’s 2016 study concerning bitter taste preferences and malevolent personality traits. Undergraduate students (n=40, mean age=19.40, 75% females) completed a laboratory component consisting of 24 samples of 8 different solutions (sucrose, sodium chloride, quinine, and citric acid with a higher and lower concentration of each) for 3 iterations, as well as PTC testing and tongue staining in order to count fungiform papillae. This was followed by a survey component that utilized HEXACO (which assesses six major domains of personality) and the IPIP-NEO scale for psychopathy (measured with the factors …

An Investigation Of The Relations Between Stress And Prospective Memory, Brandon T. Stewart

Graduate Student Theses, Dissertations, & Professional Papers

Prospective memory (PM) is a future-oriented memory system that entails “remembering to remember” intentions, or to perform actions in the future. People spend significant portions of their day-to-day lives forming and acting on intentions, and the ability to successfully generate, retain, and complete these intentions has important implications for one’s daily functioning and quality of life. Another common human experience is stress, whether that be short-term, acute stress, or long-term, chronic stress. Despite the significance and ubiquity of both PM and stress, the research base documenting the relations between them is sparse. This topic area necessitates additional research to delineate …

Characterization Of Sex Differences In The Reinforcing Effects Of Nicotine, Rodolfo Jesus Flores Garcia

Open Access Theses & Dissertations

It is presently unclear whether ovarian hormones, such as estradiol (E2) promote the reinforcing effects of nicotine in females. Thus, we compared extended access to nicotine intravenous self-administration (IVSA) in intact male, intact female, and OVX female rats (Study 1) as well as OVX females that received vehicle or E2 supplementation (Study 2). The E2 supplementation procedure involved a 4-day procedure involving 2 days of vehicle administration and 2 days of E2 administration. Two doses of E2 (25 or 250 ug) were assessed in separate groups of OVX females in order to examine the dose-dependent effects of this hormone on …

Psychopathy And The Effect Of Imitation On Empathetic Pain, Emily N. Lasko

Electronic Theses and Dissertations

Psychopathy is a disorder largely characterized by a marked deficit in empathy, however, the specificity and extent of the deficit is currently unclear. While it has been well-established in the literature that individuals higher in psychopathy tend to have intact Theory of Mind abilities and exhibit a deficient ability for affective empathy (Blair, 2005), the contribution of motor empathy to these abilities, particularly in regard to empathy for pain, has yet to be experimentally examined. Additionally, the possibility of imitation increasing motor empathic abilities has not been tested in this capacity. The goal of the current study was to further …

Antidepressant-Like Effects Of Amisulpride, Ketamine, And Their Enantiomers On Differential-Reinforcement-Of-Low-Rate (Drl) Operant Responding In Male C57/Bl/6 Mice, Doug Smith

Theses and Dissertations

Major depressive disorder (MDD) is a widespread psychiatric disorder that affects millions of people worldwide and is hypothesized to occur due to impairments in several neurotransmitter systems, including the monoaminergic and glutamatergic neurotransmitter systems. Antidepressant medications targeting multiple monoamine neurotransmitters have been shown to be effective for the treatment of depression. Racemic amisulpride is an atypical antipsychotic that has been used at low doses to treat dysthymia, a mild form of depression, and functions as an antagonist at DA_2/3, 5-HT_2B, and 5-HT₇ receptors. Recent preclinical studies have suggested that the S(+) isomer may be more …

Cannabis Use Frequency And Mood On Creativity, Caitlin Clark

Cal Poly Humboldt theses and projects

This study examines the relationship between cannabis use (infrequent, moderate, and heavy use) and one’s mood (neutral, positive, and negative) on creativity. Folk ideas of creativity and the relationships between cannabis use and mood may not reflect the real relationship between these factors (e.g. regarding cannabis use, it is perceived to be linked with higher rates of creativity; regarding mood, negative states [i.e. tortured artist] are thought to fuel creativity). Although both cannabis use and mood have been found to influence creativity independently, the current study is unique in its aims to identify whether cannabis use and mood interact to …

Are Caffeine’S Effects On Neuronal Calcium Levels Due To The Caffeine Metabolite, Paraxanthine?, Kendra Jean Hartsuyker

Cal Poly Humboldt theses and projects

Caffeine has diverse effects on neurons including, potentially, protection against Parkinson’s-related neurodegeneration. Caffeine may protect neurons from damage by limiting mitochondrial membrane permeability through a calcium-dependent mechanism. This study was a first step investigating calcium’s role in caffeine neuroprotection in vivo using zebrafish larvae. Elavl3:GCaMP6s zebrafish, which express a genetically encoded fluorescent calcium indicator protein in most CNS neurons, received caffeine (0, 50, 125, 250 µM, bath applied) in an ascending dose series during fluorescence calcium imaging of a central catecholaminergic nucleus (a proposed zebrafish homolog of the locus coeruleus, a structure affected in Parkinson’s disease). Parallel experiments tested effects …

Restoration Of Attentional Deficits After Concussion, Katharine B. Earle

Cal Poly Humboldt theses and projects

Difficulties with concentration and attention are among the most prevalent symptoms experienced after concussion. Rest has been the most common form of recovery from concussion; however, new research is suggesting mild mental exertion to be an effective aid in recovery. Drawing from Attention Restoration Theory, this study evaluated the idea that cognitive engagement with natural environments can mitigate post-concussion directed-attention deficits. A between subjects repeated measures design was used to test directed-attention after video exposure to restorative/nature and nonrestorative/city environments. Measures of mood, connectedness to environment, and symptomology scores were also collected. No meaningful difference between exposure type was found …

The Impact Of Stress On Steroid Hormones And Cue Reactivity In Smokers And Gamblers, Stephanie Elaine Wemm

Legacy Theses & Dissertations (2009 - 2024)

Addictions, both substance and behavioral, have been conceptualized as having similar biopsychosocial processes with different opportunistic expressions (Shaffer et al., 2004). Biological processes such as the hormonal response to stress as measured by cortisol, dehydroepiandrosterone (DHEA), and the ratio of the DHEA/cortisol may be among the variables underlying the disposition to develop an addictive disorder, regardless of whether it is a substance-based or a so-called behavioral addiction. The current study aimed to examine whether physiological and psychological reactions to stress are similar in high-frequency smokers and gamblers. The subjective (urges, cravings) and physiological responses (skin conductance and heart rate) of …

The Effect Of Two Modes Of Aerobic Assessment On Fifth Grade Students' Self Efficacy, Debra Roth

Walden Dissertations and Doctoral Studies

Declining youth physical activity levels and lack of aerobic fitness have been well documented with a corresponding rise in obesity levels and health issues. Based on Bandura's social cognitive theory, healthy physical activity levels and aerobic fitness are strongly connected to positive physical activity self-efficacy beliefs. This study examined whether student physical activity self-efficacy, motivation, and effort were different for the FitnessGram-® (FG) 1-Mile Run when compared to the 15-minute Aerobic Assessment Based on Improvement (AABI). A concurrent mixed method quasi-experimental approach measured 5th grade students' physical activity self-efficacy beliefs through a pretest and posttest survey while aerobic assessment scores …

The Mediating Effects Of Cortisol On The Relationship Between Conscientiousness And Judgments Of Learning, Katherine D. Miller

MSU Graduate Theses

Cortisol assists in facilitating stress response. A peak in cortisol levels can be seen between 20 and 40 minutes after exposure to the stressful event. Judgments of learning (JOLs) are within the field of metacognition and are judgments individuals make about how well they feel they have acquired the target information. Many factors influence the accuracy of these judgments, including whether they are immediate or delayed. Conscientiousness is a characteristic of personality that is associated with responsibility and organization. Individuals high in conscientiousness are more likely to have positive health related outcomes. A relationship between conscientiousness and the appraisal of …

Differentiating The Effects Of Animal-Assisted Versus Equine Facilitated Psychotherapy On Positive Psychological Outcomes Through A Stress Induction Context, Catherine J.V. Jones

Electronic Theses and Dissertations

The unique benefits of Equine Facilitated Psychotherapy (EFP) such as the human-horse bond, a non-traditional therapy setting, and performing altruistic acts are thought to facilitate positive change in humans. One mechanism by which positive changes occur is through improved coping and resilience in the face of stress. To date, only a handful of correlational studies speak to the potential effects of EFP on resilience-based outcomes. Thus, this study sought to address this gap in the literature by exploring the benefits of EFP compared to traditional Animal Assisted Therapy (AAT) in an experimental context. Specifically, we examined the effects of different …

Integrating Genetics And Neuroimaging To Study Subtypes Of Binge Drinkers, Megan E. Cooke

Theses and Dissertations

Risky alcohol use is a major health concern among college students, with 40.1% reporting binge drinking (5 or more drinks in one occasion) and 14.4% reporting heavy drinking (binge drinking on 5 or more occasions) in the past month. Risky alcohol use is thought to be the result of a complex interplay between genes, biological processes, and other phenotypic characteristics. Understanding this complex relationship is further complicated by known phenotypic heterogeneity in the development of alcohol use. Developmental studies have suggested two pathways to risky alcohol use, characterized by externalizing and internalizing characteristics, respectively. However, the underlying biological processes that …

Behavioral Deficits Across Development In A Novel Mouse Model Of Fetal Ethanol Effects, Andrew B. Hawkey

Theses and Dissertations--Psychology

Fetal Alcohol Spectrum Disorders (FASD) are a spectrum of anatomical, developmental and neurobehavioral impairments resulting from ethanol (ETOH) exposure during fetal development. Efforts to develop and screen novel pharmacotherapies against fetal ETOH effects depend heavily upon rodent models to provide indicators of the safety and efficacy of such compounds, in addition to helping better understand the underlying mechanisms to develop and test these pharmacotherapies. The following experiments describe the development of a novel mouse model of FASD using behavioral batteries to assess behavioral or cognitive deficits in juvenile and adolescent offspring (Experiment 1, Experiment 2) and whether deficits with this …