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Full-Text Articles in Biological Psychology
Caffeine Withdrawal And Dependence: A Review, Alexander Roberts
Caffeine Withdrawal And Dependence: A Review, Alexander Roberts
Williams Honors College, Honors Research Projects
With the prevalence of caffeine use increasing in modern lifestyles, it is important to look at the symptoms of caffeine use, including withdrawal and dependence, and whether these symptoms have implications for addiction. A limited number of assessments have been developed to assess caffeine withdrawal. In order to make a call for more assessments and programs to be developed to assist with healthy caffeine use, this literature review observed recent studies focusing on withdrawal and dependence. Ozsunger et al. (2009) classified caffeine withdrawal into three categories of symptoms. Three years later, Juliano et al. (2012) used an experimental approach to …
Anxiety-Like Behaviors And C-Fos Expression In Adult Zebrafish: Effects Of Housing Conditions, Alcohol And Caffeine, Adam Douglas Collier
Anxiety-Like Behaviors And C-Fos Expression In Adult Zebrafish: Effects Of Housing Conditions, Alcohol And Caffeine, Adam Douglas Collier
Dissertations
Alcohol abuse is the third largest risk factor for disease world, responsible for an estimated 3.3 million deaths each year. The concomitant ingestion of alcohol and caffeine is hypothesized to increase risk factors associated with alcohol use alone by reducing subjective effects of intoxication. The zebrafish (Danio rerio) has recently garnered attention from researchers as an effective pre-clinical in-vivo animal model in behavioral pharmacology research, largely due to small size, low-cost and ease of drug delivery. A number of studies have reported the effects of alcohol and caffeine on zebrafish behavior at a variety of doses. However, the …
Are Caffeine’S Effects On Neuronal Calcium Levels Due To The Caffeine Metabolite, Paraxanthine?, Kendra Jean Hartsuyker
Are Caffeine’S Effects On Neuronal Calcium Levels Due To The Caffeine Metabolite, Paraxanthine?, Kendra Jean Hartsuyker
Cal Poly Humboldt theses and projects
Caffeine has diverse effects on neurons including, potentially, protection against Parkinson’s-related neurodegeneration. Caffeine may protect neurons from damage by limiting mitochondrial membrane permeability through a calcium-dependent mechanism. This study was a first step investigating calcium’s role in caffeine neuroprotection in vivo using zebrafish larvae. Elavl3:GCaMP6s zebrafish, which express a genetically encoded fluorescent calcium indicator protein in most CNS neurons, received caffeine (0, 50, 125, 250 µM, bath applied) in an ascending dose series during fluorescence calcium imaging of a central catecholaminergic nucleus (a proposed zebrafish homolog of the locus coeruleus, a structure affected in Parkinson’s disease). Parallel experiments tested effects …