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Articles 361 - 390 of 3152

Full-Text Articles in Animal Studies

Canine Microwear In Relation To Diet In Sumatran Primates And African Great Apes, Putu Pujiantari Dec 2021

Canine Microwear In Relation To Diet In Sumatran Primates And African Great Apes, Putu Pujiantari

Graduate Theses and Dissertations

This thesis considers canine microwear in relation to diet in five Sumatran primates (Pongo abelii, Hylobates lar, Hylobates agilis, Presbytis thomasi, and Macaca fascicularis) and two African great apes (Pan paniscus and Pan troglodytes schweinfurthii) using both microwear texture analysis and microwear feature analysis techniques. Statistical results for texture analysis show that there are significant differences in scale of maximum and heterogeneity. This indicates that some species have large pits on their canine surfaces, having these dominated by deep features at coarse scale yet have a slight microwear heterogeneity. For feature analysis, all variables show statistically significant variation. Variance in …


Investigation Of Histomoniasis Prevention In Poultry, Lesleigh Beer Dec 2021

Investigation Of Histomoniasis Prevention In Poultry, Lesleigh Beer

Graduate Theses and Dissertations

Histomonas meleagridis is the etiological agent of histomoniasis, also commonly known as blackhead disease. This protozoal disease of poultry is detrimental to turkeys with flock mortalities often reaching 80-100%, although other gallinaceous birds are susceptible. Since the voluntary removal of nitarsone in 2015, the poultry industry is suffering with no approved prophylactics, therapeutics, or vaccines for this disease. The objectives of this dissertation were to evaluate multiple methods for prevention or control of histomoniasis, including dietary chemoprophylaxis and vaccination. Specifically, this research evaluated quinine as a chemoprophylactic candidate (Chapter 3) or live-attenuated H. meleagridis as vaccine candidates (Chapter 4) in …


Reducing Dietary Crude Protein: Characterization Of Branched-Chain Amino Acid Antagonism In Modern Broiler Chickens, Craig William Maynard Dec 2021

Reducing Dietary Crude Protein: Characterization Of Branched-Chain Amino Acid Antagonism In Modern Broiler Chickens, Craig William Maynard

Graduate Theses and Dissertations

Reducing the crude protein content of broiler diets while maintaining performance has been a primary research area in nutrition. During the late 20th century, the bulk of this research has involved supplementing broiler diets with feed-grade amino acids and proving the economic benefits of their additions. To date, widespread adoption of feed-grade amino acids is limited to methionine, lysine, threonine, and to some extent valine. With valine and isoleucine gaining prevalence in commercial formulation, classic data on the antagonisms associated with the branched-chain amino acids has returned to the forefront of practical broiler nutrition research. Therefore, a series of 23 …


An Assessment Of The Neurovascular Structures Of The Trigeminal Nerve And Their Relationship To Diet In Primates, Caitlin Yoakum Dec 2021

An Assessment Of The Neurovascular Structures Of The Trigeminal Nerve And Their Relationship To Diet In Primates, Caitlin Yoakum

Graduate Theses and Dissertations

The inferior alveolar nerve (IAN) enters the mandible via the mental foramen, supplies nervous sensation to the mandibular teeth as it travels through the mandibular canal, and exits the mandibular foramen to send information to the brain to maintain chewing cycles and protect the teeth from damage. Although bony canals and foramina have been shown to form around soft-tissue structures, there are some examples (e.g., the hypoglossal nerve/canal) where the nervous structures do not comprise most of the canal/foramina space. It is important to know the size of nerves because it has been established that larger nerves convey more information …


Efficacy Of Spirulina (Arthrospira Platensis) Utilization In Broiler Diets, Garrett James Mullenix Dec 2021

Efficacy Of Spirulina (Arthrospira Platensis) Utilization In Broiler Diets, Garrett James Mullenix

Graduate Theses and Dissertations

Spirulina (Arthrospira platensis) is a cyanobacteria microalgae that has potential as an animal feed ingredient. Five experiments were conducted to further assess its ability to serve as a protein source in broiler diets. Experiment 1 consisted of an amino acid digestibility and apparent metabolizable energy assay. The results indicated that the standardized ileal amino acid levels of spirulina are comparable with typical soybean meal. Experiment 2 assessed the performance and processing parameters of broilers fed 10% spirulina in low crude protein diets, using published digestibility coefficients. Spirulina inclusion improved footpad quality and increased redness and yellowness of the breast, skin …


Diversity, Equity And Inclusion In Human-Animal Interaction, Nira Grynheim Nov 2021

Diversity, Equity And Inclusion In Human-Animal Interaction, Nira Grynheim

Discovery Undergraduate Interdisciplinary Research Internship

No abstract provided.


Model Fitting And Analysis Of The Cost-Effectiveness Of Control Strategies In The Threatened Wildebeest-Lion Prey-Predator System In The Serengeti Ecosystem, Thadei D. Sagamiko Nov 2021

Model Fitting And Analysis Of The Cost-Effectiveness Of Control Strategies In The Threatened Wildebeest-Lion Prey-Predator System In The Serengeti Ecosystem, Thadei D. Sagamiko

Journal of Humanities and Social Sciences

In this paper, a wildebeest-lion prey-predator model for the Serengeti ecosystem was adopted from a previous publication. The threats to the model system were poaching, retaliatory killings, and droughts. The proposed threat control strategies for these threats were anti-poaching patrol to mitigate poaching, construction of strong bomas to reduce retaliatory killings, and construction of dams to mitigate the impact of droughts. Data on the lion population density in the Serengeti ecosystem were used to fit the model by using the maximum likelihood method. The impact of different control strategies for a period of five years was analysed using the incremental …


Local And Systemic Cytokine, Chemokine, And Fgf Profile In Bacterial Chondronecrosis With Osteomyelitis (Bco)-Affected Broilers, Alison Ramser, Elizabeth Greene, Robert Wideman, Sami Dridi Nov 2021

Local And Systemic Cytokine, Chemokine, And Fgf Profile In Bacterial Chondronecrosis With Osteomyelitis (Bco)-Affected Broilers, Alison Ramser, Elizabeth Greene, Robert Wideman, Sami Dridi

Poultry Science Faculty Publications and Presentations

Complex disease states, like bacterial chondronecrosis with osteomyelitis (BCO), not only result in physiological symptoms, such as lameness, but also a complex systemic reaction involving immune and growth factor responses. For the modern broiler (meat-type) chickens, BCO is an animal welfare, production, and economic concern involving bacterial infection, inflammation, and bone attrition with a poorly defined etiology. It is, therefore, critical to define the key inflammatory and bone-related factors involved in BCO. In this study, the local bone and systemic blood profile of inflammatory modulators, cytokines, and chemokines was elucidated along with inflammasome and key FGF genes. BCO-affected bone showed …


Cetacean Acousticwelfare In Wild And Managed-Care Settings: Gaps And Opportunities, Paige E. Stevens, Heather Hill, Jason N. Bruck Nov 2021

Cetacean Acousticwelfare In Wild And Managed-Care Settings: Gaps And Opportunities, Paige E. Stevens, Heather Hill, Jason N. Bruck

Faculty Publications

Cetaceans are potentially at risk of poor welfare due to the animals’ natural reliance on sound and the persistent nature of anthropogenic noise, especially in the wild. Industrial, commercial, and recreational human activity has expanded across the seas, resulting in a propagation of sound with varying frequency characteristics. In many countries, current regulations are based on the potential to induce hearing loss; however, a more nuanced approach is needed when shaping regulations, due to other non-hearing loss effects including activation of the stress response, acoustic masking, frequency shifts, alterations in behavior, and decreased foraging. Cetaceans in managedcare settings share the …


Attitude Toward Companion And Guard Dogs In Hawaii: Health And Welfare Implications, Lynn Morrison, Julie Ann Luiz Adrian, Marina Kelley, Johana Hill, Zachariah Tman, Dana-Lynn Ko'omoa-Lange Oct 2021

Attitude Toward Companion And Guard Dogs In Hawaii: Health And Welfare Implications, Lynn Morrison, Julie Ann Luiz Adrian, Marina Kelley, Johana Hill, Zachariah Tman, Dana-Lynn Ko'omoa-Lange

People and Animals: The International Journal of Research and Practice

The island of Hawaii exhibits extremes in dog welfare ranging from dogs as family members to dogs used as commodities, either as guard or hunting dogs, with many lacking appropriate care. This study offers a preliminary exploration of people’s attitudes toward companion and noncompanion dogs and the health and welfare implications for humans and dogs. Data collection included interviews and surveys conducted among 20 companion dog/human and eight guard dog/human dyads. Blood pressure (BP) was monitored during interviews to assess stress. The results of the interview data led to five themes. The first two themes describing contexts of dog welfare …


Man V.S. Wild: An Analysis Of Language Used Regarding Human-Wildlife Conflict In The Kibale National Park Community, Western Region, Uganda, Sophie Perfetto Oct 2021

Man V.S. Wild: An Analysis Of Language Used Regarding Human-Wildlife Conflict In The Kibale National Park Community, Western Region, Uganda, Sophie Perfetto

Independent Study Project (ISP) Collection

If humans are to live sustainably and in harmony with wildlife in the vicinity of Protected Areas, policy makers, and government authorities need to make informed decisions with consideration to the needs of local communities. For this to happen, policy makers must understand the perceptions of local communities and take local perspectives into account. As language is at the root of perception, language was studied in the context of its role in shaping local perceptions of human-wildlife conflict and consequential conflict mitigation strategies. Six communities around the Northern region of Kibale National Park, Uganda, were studied, with sites located in …


Discontinuity Between Religion, Law, And Society Through Animal Treatment In Morocco, Michael Altman Oct 2021

Discontinuity Between Religion, Law, And Society Through Animal Treatment In Morocco, Michael Altman

Independent Study Project (ISP) Collection

Animal treatment is a topic which is covered by many facets of what helps create the guiding principles for humans, yet all in different ways; there is some overlap, and there is some distinction. From my three months of study in Rabat, Morocco, seeing how each person approaches the homeless animal differently, I write on how three important overarching areas: religious, legal, and societal, discuss how animals should be treated.

In this paper, I will be analyzing religious texts, legal writings both in place and in draft, and will rely on external works written animal markets and on the school …


Animal-Assisted Play: A Strategy For Promoting Children’S Physical Activity Play, Jennifer A. Boisvert, W. Andrew Harrell Sep 2021

Animal-Assisted Play: A Strategy For Promoting Children’S Physical Activity Play, Jennifer A. Boisvert, W. Andrew Harrell

International Journal of Playwork Practice

This article explores how animal-assisted play might be used as a strategy in playwork to support children’s right to play, enrich their play experiences, encourage their physical activity play and better their health and life quality. Children’s interactions with pets or companion animals in free play or animal-assisted activities (AAA) can yield therapeutic benefits by increasing physical and mental health and well-being and also offer possibilities for more outdoor play, agency, risk-taking, fun and enjoyment, as well as high-quality play experiences. We invite playwork practitioners to consider the important role of animals in children’s lives and the potential value of …


Does Cortisol Respond To A Social Perturbation In Captive Bonobos?, Tiffany Ly Aug 2021

Does Cortisol Respond To A Social Perturbation In Captive Bonobos?, Tiffany Ly

Symposium of Student Scholars

All animals are influenced by their environment. For social species, this means that changes in group size or composition can have long-lasting effects on survival or reproduction. When these social species are placed in captivity and new individuals are introduced suddenly by zookeepers or researchers, these events can lead to stress by changing established dominance hierarchies. For example, these interactions can cause stress hormones—like cortisol in primates and humans—to be released in response to meeting unfamiliar individuals. We took advantage of an introduction event happening at a captive research and conservation facility to better understand how introducing a new female …


Implications Of Visual Social Access On The Welfare And Behavior Of Shelter Dogs, Christina M. Walthers, Madison J. Pattillo, Jessie A. Catchpole, Lauren E. Faulkner, Lauren N. Mitchell, Allison L. Martin Aug 2021

Implications Of Visual Social Access On The Welfare And Behavior Of Shelter Dogs, Christina M. Walthers, Madison J. Pattillo, Jessie A. Catchpole, Lauren E. Faulkner, Lauren N. Mitchell, Allison L. Martin

Symposium of Student Scholars

Animal shelter environments have many stressful factors that impact the welfare of shelter dogs, such as lack of predictability and control, and social isolation. Social isolation has been found to increase abnormal behavior and lead to poorer adoption outcomes. Providing visual access to shelter dogs is a relatively easy environmental modification that increases social opportunities and allows for more predictability and control over the environment, potentially improving welfare. To investigate the impact of visual access on the behavior of dogs, we used a within-subject design, conducting 5-min focal observations four times weekly before, during, and after visual access was provided …


Effects Of Essential Oils On Shelter Dog Behavior, Madison Pattillo Aug 2021

Effects Of Essential Oils On Shelter Dog Behavior, Madison Pattillo

Symposium of Student Scholars

Shelter environments are stressful for dogs due to loud noises and unfamiliar surroundings. Dogs rely heavily on scent information, and exposure to some scents has shown reductions in activity and vocalizations in shelter dogs. We investigated the effects of two calming (lavender and vetiver) and two stimulating (lemon and rosemary) essential oils on crate position and active, resting, and stress behaviors. Observations were conducted for 5-min intervals eight times per week, with observations split between baseline and scent exposure. Our preliminary analysis using the Wilcoxon Signed-Rank test found that dogs exposed to lavender (n = 13), lemon (n = 9), …


The Effects Of Olfactory Enrichment On Shelter Dog Behavior, Madison J. Pattillo, Lauren N. Mitchell, Jessica A. Catchpole, Allison L. Martin Aug 2021

The Effects Of Olfactory Enrichment On Shelter Dog Behavior, Madison J. Pattillo, Lauren N. Mitchell, Jessica A. Catchpole, Allison L. Martin

The Kennesaw Journal of Undergraduate Research

Shelter environments are stressful for dogs due to loud noises and unfamiliar surroundings. Previous research showed that exposure to some scents resulted in reductions in activity and vocalizations in shelter dogs. We investigated the effects of two calming (lavender and vetiver) and two stimulating (lemon and rosemary) essential oils on crate position and active, resting, and stress behaviors. There were 8, 5-min observations conducted each week per dog, split between baseline and scent exposure. Our analysis using the Wilcoxon Signed-Rank test found that dogs exposed to lavender (n = 13), lemon (n = 10), rosemary (n = …


Wild Boar In Flanders, Belgium: (Dis)Agreements Between Key Stakeholders On Wild Boar Management Objectives, Actions, And Legal Provisions, Caroline Geeraerts, Anneleen Rutten, Emma Cartuyvels, Pieter Verschelde, Sander Devisscher, Francis Turkelboom, Paul Quataert, Jim Casaer Aug 2021

Wild Boar In Flanders, Belgium: (Dis)Agreements Between Key Stakeholders On Wild Boar Management Objectives, Actions, And Legal Provisions, Caroline Geeraerts, Anneleen Rutten, Emma Cartuyvels, Pieter Verschelde, Sander Devisscher, Francis Turkelboom, Paul Quataert, Jim Casaer

Human–Wildlife Interactions

Wild boar (Sus scrofa) reappeared in Flanders, Belgium in 2006 after more than half a century of absence. Besides being a native and highly valued game species in Europe, wild boar are also known to be responsible for car collisions, crop damage, disease transmission, and ecological damage at high densities. The management of wild boar therefore seeks to balance these positive and negative impacts. Given the highly fragmented landscape in Flanders and its multifunctional use, coexistence with wild boar is only possible through integrated management involving relevant stakeholder groups. However, to be successful, this requires that the management …


Cats And Wildlife: An Animal Welfare Perspective., John Hadidian Aug 2021

Cats And Wildlife: An Animal Welfare Perspective., John Hadidian

Management - General

While there is no question that outdoors cats have an impact on wildlife, the extent and significance of this impact is the subject of considerable debate. The controversy surrounding outdoor cats can be traced back at least a century, with contemporary claims of threats to global biodiversity bringing animal welfare and conservation interests directly into opposition, largely over the means of managing conflicts. The irony in this is that cat defenders and cat detractors generally agree that it is in the best interests of cats that they should be shielded from the vagaries of outdoor life. While there are practical …


Household Perceptions And Patterns Of Crop Loss By Wild Pigs In North India, Bivash Pandav, Lakshminarayanan Natarajan, Ankit Kumar, Ajay A. Desai, Banteibor Lyngkhoi Aug 2021

Household Perceptions And Patterns Of Crop Loss By Wild Pigs In North India, Bivash Pandav, Lakshminarayanan Natarajan, Ankit Kumar, Ajay A. Desai, Banteibor Lyngkhoi

Human–Wildlife Interactions

Loss to cultivated crops by wild pigs (Sus scrofa) is widespread and can jeopardize low-income farmers. In India, although there is lot of political interest in the problem, efforts to understand the patterns, correlates, and underlying reasons for wild pig conflict continue to be minimal. We quantified loss of wheat (Triticum aestivum) to wild pigs and assessed the spatial patterns of damage in a forest settlement of Van Gujjar (Haridwar, India), which is a dairy-based pastoralist community. We chose a 4-km2 cultivated area comprising 400 farmlands (each measuring 0.8 ha and belonging to a family) and …


Interactions Between Humans, Crocodiles, And Hippos At Lake Kariba, Zimbabwe, Ivan Marowa, Joshua Matanzima, Tamuka Nhiwatiwa Aug 2021

Interactions Between Humans, Crocodiles, And Hippos At Lake Kariba, Zimbabwe, Ivan Marowa, Joshua Matanzima, Tamuka Nhiwatiwa

Human–Wildlife Interactions

Human–wildlife conflicts (HWCs) are on the increase due to shrinking space that results in increased competition for land, water, and other natural resources between humans and wildlife. Investigating the occurrence of HWCs is important in that the results can be used to formulate better management policies and strategies. In this paper, we describe the nature of HWCs emerging between humans and the Nile crocodile (Crocodylus niloticus) and between humans and the African hippopotamus (Hippopotamus amphibius; hippo) on Lake Kariba, Zimbabwe. Lake Kariba is the second largest manmade lake by volume in the world. Conflicts involving humans …


Human-Bear Conflict And Community Perceptions Of Risk In The Zanskar Region, Northern India, Kirti Chavan, Sophie M. Watts, Tsewang Namgail Aug 2021

Human-Bear Conflict And Community Perceptions Of Risk In The Zanskar Region, Northern India, Kirti Chavan, Sophie M. Watts, Tsewang Namgail

Human–Wildlife Interactions

The Himalayan brown bear (Ursus arctos isabellinus) is an endangered subspecies of brown bear (U. a. spp.) and is found throughout the Himalayan region of south and central Asia. We describe the type of and the current level of human–bear conflict (HBC) with Himalayan brown bears in the Zanskar region of northern India and suggest potential mitigation methods. Between July and September 2018, we interviewed 218 households across the Zanskar region, all of whom had experienced HBC. Participants reported increasing numbers of HBC events in the last 4 years. The most common form of HBC was damage …


Ecological Correlates Of Alligator Snapping Turtle Bite Performance, Ashley Herrin Gagnon Aug 2021

Ecological Correlates Of Alligator Snapping Turtle Bite Performance, Ashley Herrin Gagnon

Graduate Theses/Dissertations

The Alligator Snapping Turtle (Macrochelys temminckii) is one of many turtle species facing conservation challenges. Nearly extirpated in the 1980s, it is currently the subject of a head-start initiative, of which, any lasting behavioral or physiological effects were—until now—unknown! To evaluate the ability of captive-reared individuals to excel in natural habitats, and to foresee any future research or conservation challenges regarding this animal, I explored a suite of variables that influence bite performance and behaviors including captive or free-ranging status, and environmental conditions including body temperature and season. My results indicated that free-ranging M. temminckii outperform those residing …


Pilot Testing A Survey Instrument To Evaluate Eaat Professionals' Views On The Effects Of Equine-Assisted Activities And Therapies On Hope And Depression In Court-Involved Youth, Emily Stewart Aug 2021

Pilot Testing A Survey Instrument To Evaluate Eaat Professionals' Views On The Effects Of Equine-Assisted Activities And Therapies On Hope And Depression In Court-Involved Youth, Emily Stewart

Animal Science Undergraduate Honors Theses

Equine Assisted Activity and Therapy (EAAT) programs have proven beneficial for individuals with mental, physical and psychological ailments. Only in the last few years have court systems begun to utilize the complex nature of the human-horse relationship to benefit the lives of court-involved youth. Despite its novelty, the few existing studies in this field yield positive results (Frederick et al., 2015). To address the need for further research in this area, a pilot study was conducted. An exploratory survey was given to EAAT professionals to determine their views on the effects of EAAT programs on hope and depression in court-involved …


Alienation, Modernization, And Animal Welfare: Human-Animal Relationships At The Farm, State, And Country Levels, Michael D. Briscoe Aug 2021

Alienation, Modernization, And Animal Welfare: Human-Animal Relationships At The Farm, State, And Country Levels, Michael D. Briscoe

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Our relationships with animals are important for us as humans, for the environment, and for the animals themselves. In this dissertation I look at the relationships between humans and animals at three scales: farm, U.S. state, and country. Specifically, I address how factors like economic growth, technological innovation, and globalization affect human relationships with animals. Understanding how these factors influence human-animal relationships is important for improving these relationships and deciding which directions will most contribute to sustainable outcomes. I address the social factors that influence human-animal relationships in three studies.

In the first study I surveyed and interviewed dairy farmers …


Effects Of Feeding Enrichment On The Behavior Of Ex-Pet Ring-Tailed Lemurs (Lemur Catta), Amanda Rodriguez Jul 2021

Effects Of Feeding Enrichment On The Behavior Of Ex-Pet Ring-Tailed Lemurs (Lemur Catta), Amanda Rodriguez

Theses and Dissertations

Environmental enrichment is a prevailing tool used to enhance the welfare of captive species. Benefits of enrichment commonly range from promoting activity levels to reducing stereotypic/abnormal behavior. This study investigated the impact of two forms of feeding enrichment on the behavior of ring-tailed lemurs confiscated from the illegal pet trade.


Characteristics Of Non-Fatal Attacks By Black Bears: Conterminous United States, 2000–2017, Janel M. Scharhag, Cady Sartini, Shawn M. Crimmins, Scott E. Hygnstrom, Jeffrey B. Stetz Jul 2021

Characteristics Of Non-Fatal Attacks By Black Bears: Conterminous United States, 2000–2017, Janel M. Scharhag, Cady Sartini, Shawn M. Crimmins, Scott E. Hygnstrom, Jeffrey B. Stetz

Human–Wildlife Interactions

Attacks on humans by bears (Ursus spp.) have increased in recent decades, as both human and bear populations have increased. To help mitigate the risk of future attacks, it is important to understand the circumstances in past attacks. Information and analyses exist regarding fatal attacks by both American black bears (Ursus americanus) and brown bears (U. arctos) as well as non-fatal attacks by brown bears. No similarly thorough analyses on non-fatal attacks by black bears are available. Our study addressed this information gap by analyzing all (n = 210) agency-confirmed, non-fatal attacks by black …


Seasonality Of Social Behaviour Among Immature Belugas (Delphinapterus Leucas) In Managed Care, Jackson R. Ham, Malin K. Lilley, Malin R. Miller, Heather M. Manitzas Hill Jul 2021

Seasonality Of Social Behaviour Among Immature Belugas (Delphinapterus Leucas) In Managed Care, Jackson R. Ham, Malin K. Lilley, Malin R. Miller, Heather M. Manitzas Hill

Psychology Faculty Publications (Archived)

Belugas (Delphinapterus leucas ) in managed care have been reported to show seasonal variation in socio-sexual behaviour, hormone levels and respiration rates; however, little is known about the social interactions of wild belugas when they are not in summer, near-shore congregations. To better understand if belugas show seasonal variation in social interactions, this study recorded the behaviour of 10 belugas (five females, five males, ranging from birth to 10 years of age) housed in managed care. Social interactions typically peaked in the summer months but persisted at very low levels during the rest of the year. Seasonal variation was most …


Through The Lens Of The Eaat Facility Manager: Benefits Of Equine-Assisted Activities And Therapies To College-Aged Students, Annalee Parker Jul 2021

Through The Lens Of The Eaat Facility Manager: Benefits Of Equine-Assisted Activities And Therapies To College-Aged Students, Annalee Parker

Animal Science Undergraduate Honors Theses

This study aimed to explore and gather information on the benefits of equine assisted activities and therapies (EAAT) to college-aged students so that the information may be given to college students as an educational source and a mental health relief resource. This study strived to explore, through the lens of managers of EAAT organizations and their coworkers, how EAAT has positively affected college-aged students, including those with PTSD, behavioral problems, communication obstacles, Down syndrome, family differences, abusive relationships, depression, anxiety, and/or physical ailments. As a whole, EAAT is viewed as more of a recreational activity rather than a method of …


Directed Genome Evolution To Identify Genes For Macrophage Survival By Staphylococcus Agnetis, Sonali Lakshika Anne Lenaduwe Lokuge Jul 2021

Directed Genome Evolution To Identify Genes For Macrophage Survival By Staphylococcus Agnetis, Sonali Lakshika Anne Lenaduwe Lokuge

Graduate Theses and Dissertations

Bacterial Chondronecrosis with Osteomyelitis (BCO) is a debilitating infection that negatively impacts animal welfare and costs the broiler industry billions of dollars annually. We have previously isolated Staphylococcus agnetis 908 from BCO samples obtained from broilers at the University of Arkansas research farm. This isolate can induce BCO lameness at greater than 50% in broilers exposed to the pathogen in drinking water. We found that S. agnetis 908 is capable of surviving and escaping macrophages compared to a closely related cattle isolate,1379. Through Directed Genome Evolution (DGE) we identified that this difference is at least partially associated with an alanine …