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Articles 31 - 60 of 1811
Full-Text Articles in Animal Studies
Why Is Fish Welfare Still So Neglected?, Caroline M. Maia
Why Is Fish Welfare Still So Neglected?, Caroline M. Maia
Animal Sentience
Oldfield & Bonano (O&B) address an important problem in the field of fish welfare, one that calls for greater attention from scientists and practitioners. O&B show that fish welfare, particularly at the psychological level, is under-investigated. They focus mainly on zoos and aquaria, but their concerns extend also to other domains, including fish farming. Fish are sentient animals; priority should be given to their welfare in all environments where they are under human care.
The Left Ventricle Under Stress: Exploring The Impact Of Gestational Stress On Postpartum Cardiovascular Health, Archana Ramesh
The Left Ventricle Under Stress: Exploring The Impact Of Gestational Stress On Postpartum Cardiovascular Health, Archana Ramesh
Senior Theses
A woman’s cardiovascular system undergoes several changes to equip it for the physiological demands of pregnancy. The left ventricle (LV) is most susceptible to changes such as increased cardiac output and workload because it is the primary chamber in the heart that pumps oxygenated blood to the entire body. Some mothers may be unable to cope with the physiological demands, and ventricular hypertrophy, along with other cardiac remodeling that takes place during pregnancy, may bring light to underlying cardiovascular disease (CVD). The peripartum period often comes with heightened stress, disproportionately for certain populations, and this stress has been linked with …
Précis Of: "Birds, Bats And Minds: Tales Of A Revolutionary Scientist, Donald R. Griffin", Carolyn A. Ristau
Précis Of: "Birds, Bats And Minds: Tales Of A Revolutionary Scientist, Donald R. Griffin", Carolyn A. Ristau
Animal Sentience
Donald Griffin co-discovered bat sonar and founded the field of echolocation. He studied bird migration and founded Cognitive Ethology, the study of animal awareness and mental experiences. In all these endeavors, he faced hostile opposition. The biography (Ristau 2024) examines Griffin's life and the scientific explorations by him and others in these fields. This Précis emphasizes his arguments and supporting evidence for animal consciousness as well as his later research. Griffin considered the inhibiting assumptions made by scientists, including Cartesian views, the misunderstanding of innate behaviors, prejudice against lower animals, concern with violations of parsimony, and the assertions of the …
Creating Sustainable School And Home Gardens: Using Trail Cameras, Kaitlin Campbell, Kathy Cabe Trundle, Rita Hagevik
Creating Sustainable School And Home Gardens: Using Trail Cameras, Kaitlin Campbell, Kathy Cabe Trundle, Rita Hagevik
All Current Publications
Trail cameras (also called game or wildlife cameras) have been used for decades to document wildlife for personal use, education, and scientific use (documenting distributions of animals worldwide for conservation). Using a trail camera can allow us to see the biodiversity around us. Trail cameras are often used to help conserve and monitor wildlife populations. You can participate in these efforts too!
Casein Gene Polymorphism Of Goat In Thailand, Naparat Naowanat, Duangsmorn Suwattana, Boonnarong Suphap
Casein Gene Polymorphism Of Goat In Thailand, Naparat Naowanat, Duangsmorn Suwattana, Boonnarong Suphap
The Thai Journal of Veterinary Medicine
The genetic polymorphism of the casein genes and the evaluation of haplotype variability in Saanen and Thai Native breeds in Thailand were investigated. The 23 Saanen and 42 Thai Native goats were genotyped at CSN1S1, CSN2, CSN1S2, and CSN3 loci using sequencing techniques. Three variants of A, C, and E on the CSN1S1 gene locus were demonstrated. The genotypic frequencies of CSN1S1 AA, AC, and AE are shared by over 80% of the population. The CSN2 A and F alleles were observed. The CSN2 genotypes of AA, AF, and FF were indicated with the majority of AF frequency. The 2 …
The Effects Of People, Time Of Day, And Season On Affiliative And Stereotypic Behaviors In Captive Rhinoptera Bonasus And Other Rays Across Two Human-Interactive Enclosures, Wren C. A. Newman
Theses and Dissertations
Cownose rays (Rhinoptera bonasus) are among the most common species found in aquaria, yet the impact of touch enclosures on their welfare remains largely unknown. While research on animal-visitor interactions has produced mixed results for other species, the lack of studies focusing on fish welfare poses a risk of overlooking potential welfare concerns. Therefore, we aimed to establish a baseline for cownose rays regarding stereotypic behaviors, sociality, and activity in captivity, and to examine the influence of human interaction on these behaviors. We collected over 700 hours of footage from two enclosures at Adventure Aquarium in Camden, NJ …
Microplastic Accumulation In The Marsh Periwinkle (Littoraria Irrorata), Sarah Keaton, Hannah Lukhard, Eli Windy, Manar Hasan
Microplastic Accumulation In The Marsh Periwinkle (Littoraria Irrorata), Sarah Keaton, Hannah Lukhard, Eli Windy, Manar Hasan
DePaul Discoveries
Contamination of oceans by microplastics (mm) currently poses a major threat to aquatic and terrestrial ecosystems worldwide. Recent attention towards this issue has raised questions about the extent to which microplastics have accumulated in the environment, and has led to an increase in studies on the effects of microplastics in various organisms. However, levels of contamination in protected natural areas are still largely unexplored, yet can offer an important empirical perspective on the issue. In addition, little is known about the potential effects of microplastics on behavior in the field. This research was conducted within the protected ACE Basin National …
Postweaning Skull Growth In Living Didelphid Marsupials: The Case Of Gracilinanus Agilis And Cryptonanus Chacoensis, Iveth A. Villalobos Guerrero, Noé U. De La Sancha
Postweaning Skull Growth In Living Didelphid Marsupials: The Case Of Gracilinanus Agilis And Cryptonanus Chacoensis, Iveth A. Villalobos Guerrero, Noé U. De La Sancha
DePaul Discoveries
Ontogeny is described as the history of an organism through its lifetime including development, growth, and allometry. The ontogenetic approach in cranial dimensions has proved useful in interpreting evolutionary patterns. Among the largest Didelphidae family of Neotropical marsupials, the species of Gracilinanus agilis and Cryptonanus chacoensis are poorly known. In this study, we address three questions; Is there sexual dimorphism in these species? What is the pattern of allometry? Which allometric patterns best describe the patterns in the skull and mandible? We applied geometric morphometrics to describe and test these differences using MorphoJ. A discriminant function analysis was performed to …
Virtual Fencing In Livestock Management: Effects On Beef Cattle Stress And Enhancing Wildlife Conservation, Kaitlyn E. Dozler
Virtual Fencing In Livestock Management: Effects On Beef Cattle Stress And Enhancing Wildlife Conservation, Kaitlyn E. Dozler
School of Natural Resources: Dissertations, Theses, and Student Research
I examined the effects of virtual fencing on beef cattle stress and how implementing the technology can aid wildlife habitat conservation at the University of Nebraska Gudmundsen Sandhills laboratory (GSL) near Whitman, NE. First, I examined how virtual fencing influences acute heart rate changes in beef cattle fitted with the virtual fencing collars. No significant difference in the average heart rate of a cow (P > 0.05) was observed between the 30 min control and virtual fenced periods for both trial dates. Second, I examined the influence of topography on wildlife species richness and presence at GSL using wildlife camera …
Phototaxis In The Terrestrial Isopod: A Mechanism For Investigating Invertebrate Learning And Memory, Christopher Buzzelli, Jessica Kent, Chelsea Pawlak, Kevin P. Kaut
Phototaxis In The Terrestrial Isopod: A Mechanism For Investigating Invertebrate Learning And Memory, Christopher Buzzelli, Jessica Kent, Chelsea Pawlak, Kevin P. Kaut
Journal of Neuropsychology and Behavioral Processes
Isopods readily explore new environments and typically prefer contexts with lower levels of illumination (i.e., negative phototaxis). In the first of two behavioral experiments reported here, the ability of isopods to discriminate between light and dark nesting regions was confirmed, although evidence suggests an initial ‘instinctive’ draw toward a darker context. Extending these findings to experiment 2, isopods were trained against their negatively phototaxic tendency and had to exit a darkened start chamber in order to locate nesting material in a brighter chamber. Within-session improvements in latency to enter the nesting region were noted across training trials, coupled with evidence …
A Comparison Of Shaping And Imitation For Reducing A Dog’S Problem Behavior, Carlee Weir, Robbie Hanson
A Comparison Of Shaping And Imitation For Reducing A Dog’S Problem Behavior, Carlee Weir, Robbie Hanson
Theses
Over one million dogs have entered shelters in 2024 alone with approximately 31% of those dogs being relinquished by their owners (Shelter Animal Count, 2024). Further, non-aggressive behavioral issues are often cited as a primary cause for owner relinquishment (Best Friends Network Partners, 2018; Howard & DiGennaro Reed, 2014). Previous research has shown the effectiveness of training methods based on positive reinforcement to reduce problematic behavior with dogs and to increase desirable behavior, such as shaping and clicker training, and there has been a growing interest in the use of imitation during training. Fugazza and Miklosi (2015) compared a shaping …
The Influence Of Feed Additives On Laying Hen Health, Welfare, And Egg Quality, Alexa Johnson
The Influence Of Feed Additives On Laying Hen Health, Welfare, And Egg Quality, Alexa Johnson
All Dissertations
Natural feed additives like oregano essential oil and synbiotic (prebiotic and probiotic) are options with great potential for increasing the health and welfare of laying hens. The first two studies explored the effects of dietary oregano essential oil (EOO) on performance, gastrointestinal traits (GIT), blood lipids, antioxidant capacity, and egg quality in laying hens from 0 to 40 weeks of age. The third study was conducted to examine dietary EOO on layers on the shelf life and fatty acid profile of eggs. The final study aimed to examine the effects of a dietary synbiotic on agonistic behavior, plasma and brain …
Euhaplorchis Sp. A Effect On Social Behavior And Familiarity Of Gulf Killifish (Fundulus Grandis), Hannah Bauman
Euhaplorchis Sp. A Effect On Social Behavior And Familiarity Of Gulf Killifish (Fundulus Grandis), Hannah Bauman
All HCAS Student Capstones, Theses, and Dissertations
Trophically transmitted parasites may manipulate their hosts’ phenotype (e.g., behavior, physiology, morphology) to increase the likelihood of transmission to the definitive host. In fishes, stable social groups develop familiarity over time through repeated interactions among individuals, and social preferences are often developed due to familiarity. Consequently, fishes often shoal with familiar fishes, a behavior that is likely to be protective against predation. Parasites may alter fish social dynamics in two ways: by decreasing association with familiar individuals, thereby isolating infected fish and making them more susceptible to predation by definitive hosts; and/or by incentivizing uninfected individuals to avoid infected fish …
Socioecological Assessment Of Birds In Ngezi-Vumawimbi Nature Forest Reserve, Eli Taub
Socioecological Assessment Of Birds In Ngezi-Vumawimbi Nature Forest Reserve, Eli Taub
Independent Study Project (ISP) Collection
Effective management of natural resources requires consideration of the environment through both a physical and a sociological lens. In this study, the birds in Ngezi-Vumawimbi Nature Forest Reserve were examined through both a biological mist-net survey and a socioecological series of interviews with people living in the surrounding villages. The mist-net survey compared the understory species in undisturbed and disturbed area of the forest, as well as analyzing birds caught for biologically meaningful information on subspecies and sexual dimorphism. While the mist-net survey was largely unsuccessful, highlighting the need for alternative bird capture methods in Ngezi, it found a decrease …
White-Fronted Capuchins (Cebus Albifrons Aequatorialis) In La Hesperia Cloud Forest Reserve: A Study Of Aggressive Behaviors In Response To Human Presence, Marin Lynch
Independent Study Project (ISP) Collection
The Ecuadorian white-fronted capuchin, Cebus albifrons aequatorialis, is a critically endangered primate species native to Ecuador and northern Peru. Their population consists of only a handful of surviving troops spread out across this region. One surviving population exists in La Hesperia Cloud Forest Reserve in Ecuador. This reserve serves as an education and volunteer site for dozens of international travelers every year. I studied the effect of the presence of humans and the lodging they have constructed. Specifically, I investigated the effect on behavior of the proximity of the troops alpha male to manmade structures in the reserve. I …
Rock Hyrax: A Study Of Hyrax Energy Budget And Behavior Near Randilen Wildlife Management Area, Tanzania, Alice Thompson
Rock Hyrax: A Study Of Hyrax Energy Budget And Behavior Near Randilen Wildlife Management Area, Tanzania, Alice Thompson
Independent Study Project (ISP) Collection
Conducted at the gate of Randilen Wildlife Management Area (WMA), the purpose of this study was to contribute knowledge regarding rock hyraxes (Procavia capensis) through studying their energy budget and behavior. Rock hyraxes are small mammals belonging to the order hyracoidea. Despite being abundant across most of the African continent and parts of the Middle East, these herbivorous animals remain understudied in Tanzania. During the wet season of spring 2024, a total of 70 hours was applied to this research over the course of 10 days (April 7th to April 16th) using both qualitative and quantitative methods. The …
Demographic Consequences Of Off-River Nesting For Piping Plover (Charadrius Melodus) And Interior Least Tern (Sternula Antillarum Athalassos) In The Lower Platte River System, Nebraska, Elsa M. Forsberg
School of Natural Resources: Dissertations, Theses, and Student Research
Piping plovers (Charadrius melodus; hereafter, plovers) and interior least terns (Sternula antillarum athalassos; hereafter, terns) are two avian species that nest along the Lower Platte River system (LPRS) in Nebraska. In the LPRS, river sandbars provide natural nesting habitat, but off-river sites provide substantial nesting habitat especially when sandbar habitat is scarce. Although presumed to be important for the persistence of plovers and terns, off-river habitat is not self-sustaining and predicted to decline. Understanding the vital rates of plovers and terns in the LPRS will inform the role of off- river sites in the future conservation …
Vigilance And Foraging Behaviors Of Two Sciurid Species Between College Campuses And Urban Environments, Patrick Geyer, Zoe Buffington, Lorelei E. Patrick
Vigilance And Foraging Behaviors Of Two Sciurid Species Between College Campuses And Urban Environments, Patrick Geyer, Zoe Buffington, Lorelei E. Patrick
SACAD: Scholarly Activities
A comparison between the extent that sciurid specimens display vigilance and foraging behaviors on college campuses against specimens within urban environments. Observations of fox squirrels and western gray squirrels were taken from the Squirrel-Net behavioral database used for this project. We found there was a significant difference between the percent vigilance behaviors and foraging behaviors on college campuses compared to urban environments. This suggests that squirrels residing on college campuses are more desensitized to pedestrian activity and foot traffic compared to squirrels that inhabit urban areas.
Materials And Methods Developed For The Recording And Analysis Of Behavior In The Common Marmoset (Callithrix Jacchus)., Christian Wintle
Materials And Methods Developed For The Recording And Analysis Of Behavior In The Common Marmoset (Callithrix Jacchus)., Christian Wintle
UNO Student Research and Creative Activity Fair
Materials and methods developed for the recording and analysis of behavior in the common marmoset (Callithrix jacchus).
Christian J. Wintlea, Jordan B. Hernandeza,b,c, Dobromir Dotovd, and Jonathan B. Claytona,b,e,f,g
aDepartment of Biology, University of Nebraska at Omaha, Omaha, NE, USA
bNebraska Food for Health Center, University of Nebraska-Lincoln, Lincoln, NE, USA
cDepartment of Genetics, Cell Biology, and Anatomy, University of Nebraska Medical Center, NE, USA
dDepartment of Biomechanics, University of Nebraska at Omaha, Omaha, NE, USA
eDepartment of Food Science and Technology, University of Nebraska-Lincoln, Lincoln, …
Impact Of Equine Interaction During Psychotherapy On Anxiety And Depression For Residential Treatment Program Patients Experiencing Substance Withdrawal, Molly M. Friend, Molly C. Nicodemus, Clay Cavinder, Caleb Lemley, Pauline Prince, Katherine A. Cagle-Holtcamp, Rebecca M. Swanson
Impact Of Equine Interaction During Psychotherapy On Anxiety And Depression For Residential Treatment Program Patients Experiencing Substance Withdrawal, Molly M. Friend, Molly C. Nicodemus, Clay Cavinder, Caleb Lemley, Pauline Prince, Katherine A. Cagle-Holtcamp, Rebecca M. Swanson
People and Animals: The International Journal of Research and Practice
As incidences of substance use disorders (SUD) increase in the wake of the COVID-19 pandemic, there is a need for more effective treatment approaches. Further, treatment approaches currently available struggle to retain patients during the period of substance withdrawal in early treatment due to patients’ withdrawal symptoms including increased feelings of anxiety and depression. Withdrawal symptoms have been linked to dysregulated cortisol concentrations present in this period. Psychotherapy incorporating equine interaction (PIE) has emerged in other populations as a treatment that decreases cortisol concentrations and improves treatment retention. The present study investigated the impact of 4 weeks of PIE on …
Birds, Bats And Minds. Tales Of A Revolutionary Scientist: Donald R. Griffin. Volume One, Carolyn A. Ristau
Birds, Bats And Minds. Tales Of A Revolutionary Scientist: Donald R. Griffin. Volume One, Carolyn A. Ristau
eBooks
In this three-volume biography, we revisit the life and accomplishments of the revolutionary scientist, Donald R. Griffin. He encountered a lifetime of initial hostile resistance to his ideas and studies; now they are largely accepted. He and a colleague discovered the phenomenon of echolocation used by bats to navigate and capture insects, proposed that birds navigate guided by such cues as the sun and stars, and suggested that animals are likely aware, thinking and feeling beings. Forty interviews with his colleagues and friends help us understand the young emerging scientist and the mature researcher. We learn about his and others’ …
Birds, Bats And Minds. Tales Of A Revolutionary Scientist: Donald R. Griffin. Volume Two, Carolyn A. Ristau
Birds, Bats And Minds. Tales Of A Revolutionary Scientist: Donald R. Griffin. Volume Two, Carolyn A. Ristau
eBooks
In this three-volume biography, we revisit the life and accomplishments of the revolutionary scientist, Donald R. Griffin. He encountered a lifetime of initial hostile resistance to his ideas and studies; now they are largely accepted. He and a colleague discovered the phenomenon of echolocation used by bats to navigate and capture insects, proposed that birds navigate guided by such cues as the sun and stars, and suggested that animals are likely aware, thinking and feeling beings. Forty interviews with his colleagues and friends help us understand the young emerging scientist and the mature researcher. We learn about his and others’ …
Birds, Bats And Minds. Tales Of A Revolutionary Scientist: Donald R. Griffin. Volume Three, Carolyn A. Ristau
Birds, Bats And Minds. Tales Of A Revolutionary Scientist: Donald R. Griffin. Volume Three, Carolyn A. Ristau
eBooks
In this three-volume biography, we revisit the life and accomplishments of the revolutionary scientist, Donald R. Griffin. He encountered a lifetime of initial hostile resistance to his ideas and studies; now they are largely accepted. He and a colleague discovered the phenomenon of echolocation used by bats to navigate and capture insects, proposed that birds navigate guided by such cues as the sun and stars, and suggested that animals are likely aware, thinking and feeling beings. Forty interviews with his colleagues and friends help us understand the young emerging scientist and the mature researcher. We learn about his and others’ …
The Effect Of Caffeine On Bee Behavior: A Progressive Ratio Study, Kayle Cohen, Becky Hansis-O'Neill, Aimee Dunlap Dr
The Effect Of Caffeine On Bee Behavior: A Progressive Ratio Study, Kayle Cohen, Becky Hansis-O'Neill, Aimee Dunlap Dr
Undergraduate Research Symposium
This presentation focuses on the effect of caffeine on bee behavior using behavioral pharmacology methodologies. Researchers trained bumblebees to drink out of artificial flowers, then administered sucrose nectar or caffeinated sucrose nectar during a schedule of progressive and fixed ratios. The finding suggests that caffeine did increase the number of rewards during the fixed ratio, but not in the progressive ratio. However, research is still ongoing as bees continue to be tested..
Eristalis Tenax Movement Behavior In Response To Light, Temperature, And Food, Jeffery J. Zheng, Zdena M. Janderova, Jason D. Lang
Eristalis Tenax Movement Behavior In Response To Light, Temperature, And Food, Jeffery J. Zheng, Zdena M. Janderova, Jason D. Lang
Georgia Journal of Science
Drone flies, Eristalis tenax (Diptera: Syrphidae), are important generalist pollinators and visit flowers globally that range widely in color. The flies’ photoreceptors allow them to sense light wavelengths between 300-600 nm and E. tenax exhibit a positive phototactic response. To understand the effects of light on E. tenax movement, we conducted two-choice behavioral tests to determine their phototactic response to different wavelengths of light across the spectrum (ultraviolet to red light, plus full spectrum white light). The drone flies moved most and quickest toward sunlight, with almost twice the percentage of flies moving toward sunlight than toward black and …
Ms Environmental Biology Capstone Project, Reilly Miller
Ms Environmental Biology Capstone Project, Reilly Miller
Regis University Student Publications (comprehensive collection)
Habitat loss due to deforestation is a primary threat to global biodiversity. Clearing tropical rainforests for agriculture leads to forest fragmentation. Forest fragments contain fewer large trees and provide lower food availability for primates compared to continuous forests. Mantled howler monkeys inhabit the increasingly fragmented rainforests of Central and South America and may need to alter their activity and spatial cohesion to mitigate competition and preserve energy in fragments where there is lower quality food. We compared howler monkey activity and spatial cohesion across a small forest fragment (La Suerte Biological Research Station, LSBRS) and a large, continuous forest (La …
The Biobehavioral Effects Of Embryonic Exposure To Neural Inflammation And Oxidative Stress In Zebrafish, Dalton J. Anderson
The Biobehavioral Effects Of Embryonic Exposure To Neural Inflammation And Oxidative Stress In Zebrafish, Dalton J. Anderson
Honors College Theses
The purpose of this research is to improve understanding of the neurodevelopmental effects of embryonic exposure to elevated inflammation and oxidative stress induced by the antipyretic drug acetaminophen (APAP). Our study was the first to examine the interactive effects of APAP and inflammation in zebrafish embryos and how the treatments affect brain development and larval behavior. Experimental groups of zebrafish larvae were exposed to lipopolysaccharide (LPS) to induce inflammation, APAP, or LPS + APAP and larval behavior was analyzed using Ethovision automated behavioral tracking software. We also measured changes in whole-brain Glycogen Synthase Kinase 3 Beta (GSK3B) and GSK3B phosphorylation, …
Grass Rejection By Capybaras Can Be Used As A Possible Strategy To Mitigate Road Accidents, André Luiz Gama Nogueira, Sérgio Luiz Gama Nogueira-Filho, Selene Siqueira Da Cunha Nogueira, Denis Sato, Natasha Camilo Maximiano Da Silva, Lilian Elgalise Techio Pereira, Michael Mendl, Adroaldo José Zanella
Grass Rejection By Capybaras Can Be Used As A Possible Strategy To Mitigate Road Accidents, André Luiz Gama Nogueira, Sérgio Luiz Gama Nogueira-Filho, Selene Siqueira Da Cunha Nogueira, Denis Sato, Natasha Camilo Maximiano Da Silva, Lilian Elgalise Techio Pereira, Michael Mendl, Adroaldo José Zanella
Human–Wildlife Interactions
Feeding management can be a good strategy for avoiding wildlife–vehicle collisions (WVCs), which are a worldwide concern. In this study, we aimed to identify grass species that capybaras (Hydrochoerus hydrochaeris) reject as feeding material. These species could be planted to make roadsides less attractive to capybaras and, consequently, decrease WVCs involving this species. We planted 3 grass species (Brachiaria decumbens cv. Basilisk, B. hybrid Mavuno, and Zoysia japonica) in 4 blocks, applying a randomized-complete blocks design. The first 2 species we assumed would be rejected, since some animals do not consume them due to their high …
Snake Translocation Policies And Practices Within The United States, Robin E. Bedard, Megan Rottenborn, Emily Taylor
Snake Translocation Policies And Practices Within The United States, Robin E. Bedard, Megan Rottenborn, Emily Taylor
Human–Wildlife Interactions
Human–wildlife conflict with nuisance snakes (Serpentes) is rapidly increasing with human population growth and development rates. Translocation of nuisance snakes has become a widespread practice, aided by social media pages connecting people to volunteer and for-profit snake translocators. However, translocators often struggle to find information and resources from wildlife agencies about the policies required, and some may unintentionally use translocation procedures that disregard the health and survival of the snakes. The goals of this study were to (1) obtain data on policies, permitting, and training required for translocating nuisance snakes in each U.S. state that has snakes and (2) compare …
Opioid System's Potential Involvement In Ketamine's Cognitive And Antidepressant-Like Effects In Rats, Fan Zhang
Theses and Dissertations
Depression stands as one of the most pervasive mental health challenges worldwide, including the United States. Conventional antidepressants typically display a delayed onset of therapeutic action (4-8 weeks) and lack efficacy in a substantial portion of patients (over 40% of depressed patients are treatment-resistant). The dissociative anesthetic ketamine, which is a glutamatergic N-methyl-D-aspartate (NMDA) antagonist, has emerged as a promising novel treatment due to its rapid and prolonged antidepressant effects, and it is especially beneficial for treatment-resistant depression. Nevertheless, the precise neurochemical mechanisms underlying ketamine’s antidepressant properties remain elusive, hampering the development of safer and more efficacious treatments. The present …