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2024

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Articles 2581 - 2610 of 20677

Full-Text Articles in Social and Behavioral Sciences

Traversing Realities: Genres, Histories, And Politics In Popular Culture [Dialogue, Volume 2, Issue 1 (Spring 2015)], Lynnea Chapman King, Anna Cohenmiller Nov 2024

Traversing Realities: Genres, Histories, And Politics In Popular Culture [Dialogue, Volume 2, Issue 1 (Spring 2015)], Lynnea Chapman King, Anna Cohenmiller

Dialogue: The Interdisciplinary Journal of Popular Culture and Pedagogy

Editorial

Examining Perspectives and Applications, Lynnea Chapman King and A.S. CohenMiller

Articles

A Field Guide to Teaching Agency and Ethics: The West Wing and American Foreign Policy, Kayce Mobley and Sarah Fisher

Survivor Skills: Why I Want to Teach Reality TV, May Friedman

Girls, Guns, and Zombies: Five Dimensions of Teaching and Learning in The Walking Dead, Anthony Neely

“Can you imagine, a real, live Indian right here in Walnut Grove?”: American Indians in Television Adaptations of Little House on the Prairie, Amy S. Fatzinger

The Gentle Tongue: How Language Affected the World of Mister Rogers’ Neighborhood, …


Book Review: M. J. Trow, A Brief History Of Vampires, Myha Do Nov 2024

Book Review: M. J. Trow, A Brief History Of Vampires, Myha Do

Dialogue: The Interdisciplinary Journal of Popular Culture and Pedagogy

Review of M. J. Trow's A Brief History of Vampires. Philadelphia: Running Press Book Publishers, 2010. xv, 368 pages, paperback, ISBN 978-0-7624-3988-1.


Music Review: “Indy Classical Innovation: Ymusic” At Usc’S Southern Exposure New Music Series, March 21, 2014, Peter B. Kay Nov 2024

Music Review: “Indy Classical Innovation: Ymusic” At Usc’S Southern Exposure New Music Series, March 21, 2014, Peter B. Kay

Dialogue: The Interdisciplinary Journal of Popular Culture and Pedagogy

Review of “Indy Classical Innovation: yMusic” at the University of South Carolina’s Southern Exposure New Music Series, March 21, 2014.


Applications In The Classroom: Hardly Elementary—Frontiers For Freshman Composition With Conan Doyle’S A Study In Scarlet, Kate M. Donley Nov 2024

Applications In The Classroom: Hardly Elementary—Frontiers For Freshman Composition With Conan Doyle’S A Study In Scarlet, Kate M. Donley

Dialogue: The Interdisciplinary Journal of Popular Culture and Pedagogy

Three recent television and !lm adaptations testify to the continuing popularity of Arthur Conan Doyle’s consulting detective Sherlock Holmes. The fast-paced novella that introduces detective duo Holmes and Watson, A Study in Scarlet involves some astonishing elements, and not just in the plot. With just a little probing, collegiate readers may wonder whether Conan Doyle plagiarized his most famous character, invented forensic science, despised Mormons, and accidentally wrote a Western.

The novel was adapted as A Study in Pink, the !rst episode of the BBC’s series Sherlock created by Steven Moffat and Mark Gatiss. Their vision of Holmes set …


Reflection: The Twenty-Line Trap? Shakespeare Enacted By Young Women, Shannon Reed Nov 2024

Reflection: The Twenty-Line Trap? Shakespeare Enacted By Young Women, Shannon Reed

Dialogue: The Interdisciplinary Journal of Popular Culture and Pedagogy

Professional actors assemble a toolkit of monologues with an obligatory “Shakespearean monologue” of around 20 lines. But female actors are at a disadvantage, with less than 150 women in a repertoire of over 1,100 characters in Shakespeare’s 37 or more plays. Young female actors (18-22 years old) are even more at a loss, if the powerful and complex older female roles are removed, leaving only a few dozen appropriate speeches. What effect does this limited canon have on such actors? Here, I reflect upon my own participant observer experience as a young woman actor, who received the bulk of my …


Learning About People, Places And Spaces Of The World Through Informal Pedagogy: Socio-(Inter)Cultural Constructions And Connections To Popular Culture, Shelbee R. Nguyen Nov 2024

Learning About People, Places And Spaces Of The World Through Informal Pedagogy: Socio-(Inter)Cultural Constructions And Connections To Popular Culture, Shelbee R. Nguyen

Dialogue: The Interdisciplinary Journal of Popular Culture and Pedagogy

This article explores how adult and higher education (AHE) learners utilize popular culture as an informal pedagogical resource when learning about different cultures and preparing for international learning abroad or study abroad. Specifically, this case study research is concerned with what particular sources of popular culture serve as informal pedagogy and how these shape AHE learners’ cultural perceptions about study abroad to a specific international destination. A review of current literature at the intersection of popular culture and study abroad identities both the need to include adult and higher education learners as well as the ubiquitous nature of learning through …


“Can You Imagine, A Real, Live Indian Right Here In Walnut Grove?”: American Indians In Television Adaptations Of Little House On The Prairie, Amy S. Fatzinger Nov 2024

“Can You Imagine, A Real, Live Indian Right Here In Walnut Grove?”: American Indians In Television Adaptations Of Little House On The Prairie, Amy S. Fatzinger

Dialogue: The Interdisciplinary Journal of Popular Culture and Pedagogy

Laura Ingalls Wilder’s Little House novels have been adapted into two major television series: Michael Landon’s well-known series, which aired from 1974-1983, and a more recent Disney adaptation, which aired as a miniseries in 2005. The premier movie, which preceded Landon’s series, and the Disney miniseries both focus on the events in Wilder’s 1935 novel, Little House on the Prairie, which covered the period from 1869-1871 during which the Ingalls family lived among the Osage in Kansas Indian Territory. Wilder’s portrayal of the Osage in her novel is controversial, but she does also include some literary devices that allow …


Girls, Guns, And Zombies: Five Dimensions Of Teaching And Learning In The Walking Dead, Anthony Neely Nov 2024

Girls, Guns, And Zombies: Five Dimensions Of Teaching And Learning In The Walking Dead, Anthony Neely

Dialogue: The Interdisciplinary Journal of Popular Culture and Pedagogy

Rooted in sociocultural theory, this article utilizes a conceptual framework derived from Alexander, Schallert, and Reynolds’ four topographical dimensions of learning: who of learning, what of learning, where of learning, and when of learning. Situated learning (Lave and Wenger) is presented as a fifth dimension to address how learning occurs in communities of practice absent of formal schooling. Content analysis (Elo and Kyngass) is used to analyze a teaching and learning event from an episode of The Walking Dead based on the five topographical dimensions of learning listed above. Findings provide insights for pedagogical application for …


Survivor Skills: Authenticity, Representation And Why I Want To Teach Reality Tv, May Friedman Nov 2024

Survivor Skills: Authenticity, Representation And Why I Want To Teach Reality Tv, May Friedman

Dialogue: The Interdisciplinary Journal of Popular Culture and Pedagogy

This paper will consider the pedagogical potential in constructing a class on the phenomenon of reality television by exploring the possibilities and pitfalls of a shared viewing of these “texts” as a site of critical engagement with popular culture. A course on reality TV would require a deep analysis of the topics of representation, authenticity, and audience reactions. The course I would like to teach would also consider the ways that reality TV is simultaneously emblematic of, and contributes to, the foregrounding of neoliberal discourses. This paper addresses some of the pedagogical implications of an analysis of reality TV by …


A Field Guide To Teaching Agency And Ethics: The West Wing And American Foreign Policy, Kayce Mobley, Sarah Fisher Nov 2024

A Field Guide To Teaching Agency And Ethics: The West Wing And American Foreign Policy, Kayce Mobley, Sarah Fisher

Dialogue: The Interdisciplinary Journal of Popular Culture and Pedagogy

Though political science undergraduate courses reflect a rich theoretical tradition, they typically lack opportunities for students to express intangible concepts through the interpretation of creative works, a standard exercise of critical analysis. Educators can address this dearth in many ways, such as through utilization of popular culture texts. We employ the television series The West Wing to ground debates in American politics, specifically American foreign policy. Although this show has been on air since 2006, Netflix and Amazon have recently released the entire series for streaming, significantly reducing the hassle and monetary cost of using this source in the classroom. …


Editorial: Examining Perspectives And Applications, Lynnea Chapman King, Anna Cohenmiller Nov 2024

Editorial: Examining Perspectives And Applications, Lynnea Chapman King, Anna Cohenmiller

Dialogue: The Interdisciplinary Journal of Popular Culture and Pedagogy

The editors and contributors of Dialogue: The Interdisciplinary Journal of Popular Culture and Pedagogy are pleased to present Volume 2, Issue 1, “Traversing Realities: Genres, Histories, and Politics in Popular Culture.”


“We Don’T Do That”: Negotiating Graduate Education As A Bisexual+ Student, Kaity Prieto, Victoria B. Olivo Nov 2024

“We Don’T Do That”: Negotiating Graduate Education As A Bisexual+ Student, Kaity Prieto, Victoria B. Olivo

Journal of Queer and Trans Studies in Education

Bisexual+ people comprise the largest portion of the queer and trans community, yet there is limited research on bi+ subpopulations and a particular absence of literature exploring bisexual+ student identities and experiences. Much of the extant bi+ college student literature has centered on undergraduate experiences, leaving graduate experiences underexplored. Through this narrative inquiry study, guided by a queer theoretical framework, we sought to understand how bi+ graduate students navigate academic and professional contexts and how systems of power influence their identity negotiation narratives. Findings revealed pervasive bisexual+ erasure in academic contexts, pressure to conform to normative notions of professionalism, and …


Health Outcomes Reported By Healthcare Providers And Clients Of A Community-Based Medically Tailored Meal Program, Jessica M Sautter, Jule Anne Henstenburg, Adrian Glass Crafford, Ian Rowe-Nicholls, Victor S Diaz, Kaitlyn Ann Bartholomew, Julia S Evans, Maria R Johnson, Jeffrey Zhou, Deeksha Ajeya Nov 2024

Health Outcomes Reported By Healthcare Providers And Clients Of A Community-Based Medically Tailored Meal Program, Jessica M Sautter, Jule Anne Henstenburg, Adrian Glass Crafford, Ian Rowe-Nicholls, Victor S Diaz, Kaitlyn Ann Bartholomew, Julia S Evans, Maria R Johnson, Jeffrey Zhou, Deeksha Ajeya

Rowan-Virtua School of Osteopathic Medicine Departmental Research

BACKGROUND: Medically tailored meal (MTM) programs provide home-delivered meals to people living with serious illness and poor nutritional status. Client outcome studies have found evidence of decreased healthcare utilization and cost savings associated with MTM program participation, and inconclusive evidence of change in health measures. The purpose of this study was to use a novel observational framework to describe the client profile and change in health outcomes using routinely collected health and program data from a community-based MTM program at MANNA (Philadelphia, PA).

METHODS: Clients reported their self-rated health and experiences of food insecurity and malnutrition. Healthcare providers reported clients' …


Introducing Zippy: Digitizing Our Collections One Clip At A Time, Heidi J. Southworth, Leah Zacate Nov 2024

Introducing Zippy: Digitizing Our Collections One Clip At A Time, Heidi J. Southworth, Leah Zacate

Library Services Publications

The University Archives and Southern Minnesota Historical Center at Minnesota State University, Mankato recently purchased a large format overhead scanner from the Crowley Company. We’d like to share what we purchased and why, and how Zippy (yes, we named our scanner) has changed our digitization possibilities and workflows.


The Wallet And The Gut: Forecasting The 2024 Presidential Election With A State-By-State Adaptation Of The Time-For-Change Model, Simeon A. Betapudi, Hadassah Betapudi Nov 2024

The Wallet And The Gut: Forecasting The 2024 Presidential Election With A State-By-State Adaptation Of The Time-For-Change Model, Simeon A. Betapudi, Hadassah Betapudi

Science University Research Symposium (SURS)

This study adapts Abramowitz's Time-for-Change model to a state-level framework to forecast the 2024 U.S. presidential election. The Time-for-Change model’s focus on the popular vote has become less relevant in recent years, given the growing divergence between popular vote outcomes and electoral college results. Our model addresses these issues by adapting the original Time-for-Change predictors (presidential approval rating, GDP, and time in office) to the state level. Using data from five election cycles (2004–2020), we employ an Ordinary Least Squares (OLS) regression to predict incumbent two-party vote share. Unlike the original model, state-level GDP and incumbency duration were found to …


Staff Education On Effective Communication Techniques, Victorine Kebei Tangwa Nov 2024

Staff Education On Effective Communication Techniques, Victorine Kebei Tangwa

Walden Dissertations and Doctoral Studies

The doctor of nursing (DNP) staff education project took place in a group home with staff who care for six individuals with intellectual and physical disabilities. A gap in practice related to ineffective communication between staff and individuals with intellectual and physical disabilities was identified. The practice focused question attempted to answer whether educating staff on effective communication would increase staff knowledge. The purpose of this project was to educate staff on the ability to communicate effectively with individuals. The literature supported the need for the project. Nine nurses voluntarily participated in the project. After receiving the ethics approval from …


Cross-Country Comparison Of Depressive Symptoms And Social-Emotional Aspects In University Students From Brazil And Germany During The Covid-19 Pandemic: Results From Two Cross-Sectional Surveys, Aneliana Da Silva Prado, Sabrina Baldofski, Elisabeth Kohls, Alessandra S. Bianchi, Fernanda S. Oda, Joanneliese De Lucas Freitas, Christine Rummel-Kluge Nov 2024

Cross-Country Comparison Of Depressive Symptoms And Social-Emotional Aspects In University Students From Brazil And Germany During The Covid-19 Pandemic: Results From Two Cross-Sectional Surveys, Aneliana Da Silva Prado, Sabrina Baldofski, Elisabeth Kohls, Alessandra S. Bianchi, Fernanda S. Oda, Joanneliese De Lucas Freitas, Christine Rummel-Kluge

Pacific Faculty Work

Background The COVID-19 pandemic negatively affected students' mental health, increasing pre-existing psychosocial vulnerabilities. University students worldwide have presented differences in their mental health status; however, cross-country studies comparing students' mental health during the pandemic are lacking. Aims To investigate potential differences between university students from Brazil and those from Germany with respect to (a) depressive symptoms and alcohol and drug consumption, (b) social and emotional aspects (loneliness, self-efficacy, perceived stress, social support and resilience) and (c) attitudes towards vaccination. Method Two online cross-sectional studies were conducted with university students during the COVID-19 pandemic in Brazil (November 2021 to March 2022) …


Restoring And Improving Senior Citizens' Trust In Water Safety In Flint, Michigan, Jessica Nichole Burt Nov 2024

Restoring And Improving Senior Citizens' Trust In Water Safety In Flint, Michigan, Jessica Nichole Burt

Walden Dissertations and Doctoral Studies

Trust can be defined as a belief in truth, hope, or simply the idea that a person or group has the best interest or ability of the next party. During the Flint, Michigan, water crisis, trust significantly impacted how a person or group perceived the person deemed dependable when decisions made impacted their life. The purpose of this study was to explore senior citizens' experiences and perceptions and make recommendations for restoring the public's confidence in water safety in Flint, Michigan, which has been fragmented within the minority senior community. A qualitative case study was designed by using interviews to …


‘Foundations Of The Mind, Brain, And Behavioral Relationships’: A Combined Faculty And Student’S Perspective Of A New Textbook On Clinical Neuroscience, Richard J. Addante, Jahdiel Perez Caban, Sarah E. Smith Nov 2024

‘Foundations Of The Mind, Brain, And Behavioral Relationships’: A Combined Faculty And Student’S Perspective Of A New Textbook On Clinical Neuroscience, Richard J. Addante, Jahdiel Perez Caban, Sarah E. Smith

Psychology Faculty Publications

The textbook, ‘Foundations of the Mind, Brain, and Behavioral Relationships’ (Moini et al., Citation2023), is one of the newest textbooks in neuroscience to arrive. The market for textbooks in the field of neuroscience is competitive among several excellent comparators, but critical market gaps still remain to be filled, notably the area of clinical neuroscience that is both advanced in content but accessible to students. One of the reasons that this gap has existed in the field is precisely because it can be a very difficult a mark to hit: how does one present neurobiological content that is …


Readability Metrics In Patient Education: Where Do We Innovate?, Som Singh, Aleena Jamal, Fawad Qureshi Nov 2024

Readability Metrics In Patient Education: Where Do We Innovate?, Som Singh, Aleena Jamal, Fawad Qureshi

SKMC Student Presentations and Publications

The increasing use of digital applications in healthcare has led to a greater need for patient education materials. These materials, often in the form of pamphlets, booklets, and handouts, are designed to supplement physician-patient communication and aim to improve patient outcomes. However, the effectiveness of these materials can be hindered by variations in patient health literacy. Readability, a measure of text comprehension, is a key factor influencing how well patients understand these educational materials. While there has been growing interest in readability assessment in medicine, many studies have demonstrated that digital texts do not frequently meet the recommended sixth-to-eighth grade …


Incorporating Ai Literacy Into Music Library Instruction: An Interactive Discussion, Taylor J. Greene Nov 2024

Incorporating Ai Literacy Into Music Library Instruction: An Interactive Discussion, Taylor J. Greene

Library Presentations, Posters, and Audiovisual Materials

Taylor Greene gave a presentation connecting AI Literacy to his work not only as the liaison to the Hall-Musco Conservatory of Music but also more broadly in his role as Chair of Research and Instructional Services. He began by providing an overview of Chapman University’s cautious approach to embracing generative AI and highlighted the library’s role in supporting faculty, staff, librarians, and students in better understanding these technologies and their potential impact on higher education. He summarized the work of the AI Task Force and offered a general overview of the AI Literacy lectures that he and Dr. Doug Dechow …


11.04.2024 Orsp Connect, Liz Williamson Nov 2024

11.04.2024 Orsp Connect, Liz Williamson

ORED Newsletter

Small Grant Program for Faculty

Mid-South REACH Product Dev Grant

NSF Virtual Grants Conference


Relationship Between Social Media And Acts Of Domestic Terrorism And Extremism, Winford Rochelle Craig Nov 2024

Relationship Between Social Media And Acts Of Domestic Terrorism And Extremism, Winford Rochelle Craig

Walden Dissertations and Doctoral Studies

After 9/11, domestic terrorism began to evolve in the United States and technological advances and the usage of social media (SM) increased exponentially. During the same era, technological advancement intensified and SM became one primary method of communication between extremists. SM has infiltrated into multiple segments of society, and became a method of transference of ideology, to the population of the United States. Domestic violent extremism (DVE) groups used SM to indoctrinate, train, and recruit individuals throughout the United States. The purpose of this quantitative study was to explore the relationship between the increased usage of SM and the rise …


A Method To Incorporate Transition Risk Stress Testing Into Probability Of Default (Pd) Models For Retail Portfolios, Aneta Ptak-Chmielewska, Paweł Kopciuszewski, Alvaro Fernandez Toledo Nov 2024

A Method To Incorporate Transition Risk Stress Testing Into Probability Of Default (Pd) Models For Retail Portfolios, Aneta Ptak-Chmielewska, Paweł Kopciuszewski, Alvaro Fernandez Toledo

Journal of Banking and Financial Economics

Climate risk is one of the type of risks in a bank’s portfolio which is not fully recognized, and its impact on the future overall risk changes is hidden due to lack of sufficient knowledge at the moment. One of the most common data comes from Network for Greening the Financial System (NGFS) scenarios related to climate change (physical risk) and climate policy and technology trends (transition risk). In the paper we focused on the transition risk scenarios and their impact on the economy and in particular on credit risk. Our main goal was to check the tendency in the …


Cultural Normative Beliefs In The U.S. As A Determinant Of Negative Dental Experiences And Dental Anxiety: A Preliminary Investigation, Andrew L. Geers, Laura D. Seligman, Keenan A. Pituch, Kelly S. Clemens, Sarah Francis, Lauren Kramer, Emily K. Spotts, Michael Vang Nov 2024

Cultural Normative Beliefs In The U.S. As A Determinant Of Negative Dental Experiences And Dental Anxiety: A Preliminary Investigation, Andrew L. Geers, Laura D. Seligman, Keenan A. Pituch, Kelly S. Clemens, Sarah Francis, Lauren Kramer, Emily K. Spotts, Michael Vang

Psychological Science Faculty Publications

Dental anxiety, a predictor of both dental treatment avoidance and health outcomes, has been linked with early negative dental experiences. The causes of this relationship remain largely unexplored. This study provides a preliminary exploration of within-cultural variations of dental normative beliefs on the perception of negative dental experiences and the subsequent experience of dental anxiety in the U.S. A sample of 190 U.S. adults recruited from Amazon’s MTurk completed measures of cultural normative beliefs about oral health care, age and fear at first dental visit, history of negative dental experiences, and dental anxiety. Factor analysis yielded support for a three-factor …


Social Workers' Challenges And Successes In Working With Black Men During Times Of Social Upheaval., Eric Dewayne Franklin Nov 2024

Social Workers' Challenges And Successes In Working With Black Men During Times Of Social Upheaval., Eric Dewayne Franklin

Walden Dissertations and Doctoral Studies

U.S. social workers experienced challenges and successes when working with Black male clients in mental and medical health and addiction therapy or treatment settings before and during the simultaneous events of the COVID-19 pandemic, political elections, and racial violence/social injustice movements of the late 2010s–early 2020s. This project addressed the lack of knowledge regarding evidence-based practices to address the challenges and positive therapeutic experiences of social workers, specifically those working in clinical practice with Black American male clients. The theoretical framework for this study was Bell's critical race theory. The generic qualitative research design was used to address three research …


Suicide Bereavement And Community Resource Use From A Clinician’S Perspective, Kristina Rose Culpepper Nov 2024

Suicide Bereavement And Community Resource Use From A Clinician’S Perspective, Kristina Rose Culpepper

Walden Dissertations and Doctoral Studies

Social workers, clinicians, and mental health professionals commonly work to positively influence their client’s lives. Social workers specifically abide by the principle of pursuing social change for vulnerable populations. As suicide remains one of the top mental health concerns worldwide, the suicide-loss population continues to grow. Suicide loss is a social problem that affects all cultures and impacts individuals and communities. The suicide-loss population is vulnerable with seemingly limited research-based interventions and resources. The research addressed how clinicians describe the availability and benefit of community resources at each system level. This study was guided by systems theory, which allows clinicians …


Predictive Validity Of Person-Environment Fit On The Hiring Desirability Of Software Engineers, Lucija Velican Nov 2024

Predictive Validity Of Person-Environment Fit On The Hiring Desirability Of Software Engineers, Lucija Velican

Walden Dissertations and Doctoral Studies

Person-environment (P-E) fit, particularly in recruitment, has gained significant attention, expanding beyond the traditional focus on job-applicant compatibility to include alignment with team and organizational dynamics. Despite its importance, there is no consensus on how to effectively measure this fit, which limits its predictive power for employee outcomes. This quantitative correlational study addressed this gap by examining the predictive validity of congruence between candidates’ psychological characteristics and various facets of the work environment among software engineers. Drawing on Schneider’s attraction-selection-attrition model, the study examined congruence at multiple levels (candidate-team, candidate-leader, and candidate-role) and its influence on hiring desirability. Secondary data …


Euphemism In Ai Discourse As Colonial Harm & Effect: Learnings From Subaltern Puerto Rico, Jacqueline Oquendo Nov 2024

Euphemism In Ai Discourse As Colonial Harm & Effect: Learnings From Subaltern Puerto Rico, Jacqueline Oquendo

LSU Doctoral Dissertations

Through three integrated studies, this dissertation explores complex human-AI interactions by comparing the perceptions of two groups of U.S. citizens: subaltern Puerto Ricans and stateside Americans’ interactions with ChatGPT. This corpus-assisted Critical Discourse Analysis or CLCDA, triangulated with 1:1 semi-structured interviews, validates scholars’ concerns about the biases inherent in generative AI. Contributing to those concerns, this dissertation reveals that ChatGPT deploys discourse strategies that, when executed, facilitate digital colonialism. Euphemistic language is prominent among its discourse strategies, replacing controversial words, phrases, and topics with more palatable ones. When prompted on events of historical significance, I find that ChatGPT’s discourse obscures …


Nerve Injury Inhibits Oprd1 And Cnr1 Transcription Through Rest In Primary Sensory Neurons, Ashok Subedi, Asieh Etemad, Aadhya Tiwari, Yuying Huang, Biji Chatterjee, Samantha M Mcleod, Yungang Lu, Diangelo Gonzalez, Krishna Ghosh, Mario Sirito, Sanjay K Singh, Elisa Ruiz, Sandra L Grimm, Cristian Coarfa, Hui-Lin Pan, Sadhan Majumder Nov 2024

Nerve Injury Inhibits Oprd1 And Cnr1 Transcription Through Rest In Primary Sensory Neurons, Ashok Subedi, Asieh Etemad, Aadhya Tiwari, Yuying Huang, Biji Chatterjee, Samantha M Mcleod, Yungang Lu, Diangelo Gonzalez, Krishna Ghosh, Mario Sirito, Sanjay K Singh, Elisa Ruiz, Sandra L Grimm, Cristian Coarfa, Hui-Lin Pan, Sadhan Majumder

Faculty, Staff and Students Publications

The transcription repressor REST in the dorsal root ganglion (DRG) is upregulated by peripheral nerve injury and promotes the development of chronic pain. However, the genes targeted by REST in neuropathic pain development remain unclear. The expression levels of four opioid receptor genes (Oprm1, Oprd1, Oprl1 and Oprk1) and the cannabinoid CB1 receptor (Cnr1) gene in the DRG regulate nociception. In this study, we determined the role of REST in controlling their expression in the DRG induced by spared nerve injury (SNI). SNI induced chronic pain hypersensitivity in wild-type mice and was accompanied by increased levels of Rest transcript and …