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Bayesian inference

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Full-Text Articles in Statistical Models

Multiscale Modelling Of Brain Networks And The Analysis Of Dynamic Processes In Neurodegenerative Disorders, Hina Shaheen Jan 2024

Multiscale Modelling Of Brain Networks And The Analysis Of Dynamic Processes In Neurodegenerative Disorders, Hina Shaheen

Theses and Dissertations (Comprehensive)

The complex nature of the human brain, with its intricate organic structure and multiscale spatio-temporal characteristics ranging from synapses to the entire brain, presents a major obstacle in brain modelling. Capturing this complexity poses a significant challenge for researchers. The complex interplay of coupled multiphysics and biochemical activities within this intricate system shapes the brain's capacity, functioning within a structure-function relationship that necessitates a specific mathematical framework. Advanced mathematical modelling approaches that incorporate the coupling of brain networks and the analysis of dynamic processes are essential for advancing therapeutic strategies aimed at treating neurodegenerative diseases (NDDs), which afflict millions of …


A Bayesian Programming Approach To Car-Following Model Calibration And Validation Using Limited Data, Franklin Abodo Jun 2022

A Bayesian Programming Approach To Car-Following Model Calibration And Validation Using Limited Data, Franklin Abodo

FIU Electronic Theses and Dissertations

Traffic simulation software is used by transportation researchers and engineers to design and evaluate changes to roadway networks. Underlying these simulators are mathematical models of microscopic driver behavior from which macroscopic measures of flow and congestion can be recovered. Many models are intended to apply to only a subset of possible traffic scenarios and roadway configurations, while others do not have any explicit constraint on their applicability. Work zones on highways are one scenario for which no model invented to date has been shown to accurately reproduce realistic driving behavior. This makes it difficult to optimize for safety and other …


Point Process Modelling Of Objects In The Star Formation Complexes Of The M33 Galaxy, Dayi Li Apr 2020

Point Process Modelling Of Objects In The Star Formation Complexes Of The M33 Galaxy, Dayi Li

Electronic Thesis and Dissertation Repository

In this thesis, Gibbs point process (GPP) models are constructed to study the spatial distribution of objects in the star formation complexes of the M33 galaxy. The GPP models circumvent the limitations of the two-point correlation function employed in the current astronomy literature by naturally accounting for the inhomogeneous distribution of these objects. The spatial distribution of these objects serves as a sensitive probe in understanding the star formation process, which is crucial in understanding the formation of galaxies and the Universe. The objects under study include the CO filament structure, giant molecular clouds (GMCs) and young stellar cluster candidates …


Exploring The Estimability Of Mark-Recapture Models With Individual, Time-Varying Covariates Using The Scaled Logit Link Function, Jiaqi Mu Aug 2019

Exploring The Estimability Of Mark-Recapture Models With Individual, Time-Varying Covariates Using The Scaled Logit Link Function, Jiaqi Mu

Electronic Thesis and Dissertation Repository

Mark-recapture studies are often used to estimate the survival of individuals in a population and identify factors that affect survival in order to understand how the population might be affected by changing conditions. Factors that vary between individuals and over time, like body mass, present a challenge because they can only be observed when an individual is captured. Several models have been proposed to deal with the missing-covariate problem and commonly impose a logit link function which implies that the survival probability varies between 0 and 1. In this thesis I explore the estimability of four possible models when survival …


Modelling Weighted Signed Networks, Alberto Caimo, Isabella Gollini Jun 2019

Modelling Weighted Signed Networks, Alberto Caimo, Isabella Gollini

Conference papers

In this paper we introduce a new modelling approach to analyse weighted signed networks by assuming that their generative process consists of two models: the interaction model which describes the overall connectivity structure of the relations in the network without taking into account neither the weight nor the sign of the dyadic relations; and the conditional weighted signed network model describes how the edge signed weights form given the interaction structure. We then show how this modelling approach can facilitate the interpretation of the overall network process. Finally, we adopt a Bayesian inferential approach to illustrate the new methodology by …


Bayesian Analysis For The Intraclass Model And For The Quantile Semiparametric Mixed-Effects Double Regression Models, Duo Zhang Jan 2019

Bayesian Analysis For The Intraclass Model And For The Quantile Semiparametric Mixed-Effects Double Regression Models, Duo Zhang

Dissertations, Master's Theses and Master's Reports

This dissertation consists of three distinct but related research projects. The first two projects focus on objective Bayesian hypothesis testing and estimation for the intraclass correlation coefficient in linear models. The third project deals with Bayesian quantile inference for the semiparametric mixed-effects double regression models. In the first project, we derive the Bayes factors based on the divergence-based priors for testing the intraclass correlation coefficient (ICC). The hypothesis testing of the ICC is used to test the uncorrelatedness in multilevel modeling, and it has not well been studied from an objective Bayesian perspective. Simulation results show that the two sorts …


Inference From Network Data In Hard-To-Reach Populations, Isabelle Beaudry Mar 2017

Inference From Network Data In Hard-To-Reach Populations, Isabelle Beaudry

Doctoral Dissertations

The objective of this thesis is to develop methods to make inference about the prevalence of an outcome of interest in hard-to-reach populations. The proposed methods address issues specific to the survey strategies employed to access those populations. One of the common sampling methodology used in this context is respondent-driven sampling (RDS). Under RDS, the network connecting members of the target population is used to uncover the hidden members. Specialized techniques are then used to make inference from the data collected in this fashion. Our first objective is to correct traditional RDS prevalence estimators and their associated uncertainty estimators for …


Ordinal Probit Wavelet-Based Functional Models For Eqtl Analysis, Mark J. Meyer, Jeffrey S. Morris, Craig P. Hersh, Jarret D. Morrow, Christoph Lange, Brent A. Coull Jan 2015

Ordinal Probit Wavelet-Based Functional Models For Eqtl Analysis, Mark J. Meyer, Jeffrey S. Morris, Craig P. Hersh, Jarret D. Morrow, Christoph Lange, Brent A. Coull

Jeffrey S. Morris

Current methods for conducting expression Quantitative Trait Loci (eQTL) analysis are limited in scope to a pairwise association testing between a single nucleotide polymorphism (SNPs) and expression probe set in a region around a gene of interest, thus ignoring the inherent between-SNP correlation. To determine association, p-values are then typically adjusted using Plug-in False Discovery Rate. As many SNPs are interrogated in the region and multiple probe-sets taken, the current approach requires the fitting of a large number of models. We propose to remedy this by introducing a flexible function-on-scalar regression that models the genome as a functional outcome. The …


Acceptance-Rejection Sampling With Hierarchical Models, Christian A. Ayala Jan 2015

Acceptance-Rejection Sampling With Hierarchical Models, Christian A. Ayala

CMC Senior Theses

Hierarchical models provide a flexible way of modeling complex behavior. However, the complicated interdependencies among the parameters in the hierarchy make training such models difficult. MCMC methods have been widely used for this purpose, but can often only approximate the necessary distributions. Acceptance-rejection sampling allows for perfect simulation from these often unnormalized distributions by drawing from another distribution over the same support. The efficacy of acceptance-rejection sampling is explored through application to a small dataset which has been widely used for evaluating different methods for inference on hierarchical models. A particular algorithm is developed to draw variates from the posterior …


Semiparametric Regression In Capture-Recapture Modelling, O. Gimenez, C. Barbraud, Ciprian M. Crainiceanu, S. Jenouvrier, B.T. Morgan Dec 2004

Semiparametric Regression In Capture-Recapture Modelling, O. Gimenez, C. Barbraud, Ciprian M. Crainiceanu, S. Jenouvrier, B.T. Morgan

Johns Hopkins University, Dept. of Biostatistics Working Papers

Capture-recapture models were developed to estimate survival using data arising from marking and monitoring wild animals over time. Variation in the survival process may be explained by incorporating relevant covariates. We develop nonparametric and semiparametric regression models for estimating survival in capture-recapture models. A fully Bayesian approach using MCMC simulations was employed to estimate the model parameters. The work is illustrated by a study of Snow petrels, in which survival probabilities are expressed as nonlinear functions of a climate covariate, using data from a 40-year study on marked individuals, nesting at Petrels Island, Terre Adelie.