Statistical Models Commons^™

Reexamining The Croton Aqueduct: A Ward-Level Microhistorical Analysis Of Infrastructure And Cholera Mortality In 1849 New York City, Alexandria R. Toothman

Dissertations, Theses, and Capstone Projects

This work reexamines the Croton Aqueduct’s role in public health by shifting analysis from the citywide level to the ward level, revealing that infrastructure expansion did not produce uniform benefits across New York City. When the Croton Aqueduct opened in 1842, it was celebrated as an achievement that would deliver pure water and eliminate disease. However, only seven years after its opening, in 1849, cholera returned with greater force in the Sixth Ward. This work shows that the uneven distribution of Croton infrastructure corresponded with uneven cholera mortality rates, challenging narratives that present Croton as a singular triumph of urban …

Computational Insights Into Nucleosome Dynamics In Epigenetics Using Molecular Dynamics Simulations, Rutika Patel

Dissertations, Theses, and Capstone Projects

Nucleosome core particles (NCP) are the building blocks that form a highly organized and compact chromatin structure. Nucleosomes package DNA in the nucleus of eukaryotic cells. The NCP consists of about 147 base pairs of DNA wrapped around the histone octamer, with 1.65 superhelical turns in a left-handed manner. The histone octamer is composed of two copies of H3, H4, H2A, and H2B. Together with histone H1 and linker DNA, they further assemble into a higher-order chromatin structure. The nucleosome complex is stabilized by electrostatic interactions between positively charged histone residues and the negatively charged DNA backbone. To effectively access …

A Predictive Coding Account Of Spatial Working Memory Following Prophylactic Levetiracetam Administration Prior To Traumatic Brain Injury, Omeima Mutwali

Dissertations, Theses, and Capstone Projects

Traumatic brain injury (TBI) symptom prevention and remediation is an important area of research that would benefit vulnerable groups, including active-duty and veteran soldiers. These patients can sustain penetrative forces in fields of combat or in training, which result in focal lesions that trigger inflammatory and degenerative processes in the brain. Both primary and secondary injuries are associated with changes to cognition, behavior and affective state. This disease poses increased risk of epileptogenesis, as well. Given these outcomes, prior research has evaluated levetiracetam (LEV) as a prophylactic treatment for seizures, cognitive deficits and negative emotionality. LEV acts as a presynaptic …

How Argentina Won The 2022 Fifa Men's World Cup: A Data Story, Aniruddha Parthasarathy

Dissertations, Theses, and Capstone Projects

This project analyzes Argentina’s 2022 FIFA Men’s World Cup win using open-source football (soccer) data. The project evaluates the team’s performance at a micro-level across three domains: without possessing the ball, possessing the ball and the team’s in-game management tactics. A statistical framework, i.e., multiple linear regression modeling, was used to identify the five key defensive actions influencing the Argentinian team’s intensity of pressure applied, and visualized by heatmaps and time-segmented plots. More specifically, an Expected Threat (xT) analysis quantified the threat or danger from passes and progressive carries (moving the ball at least 10 meters), revealing that Lionel Messi’s …

Modeling Of Covid-19 Clinical Outcomes In Mexico: An Analysis Of Demographic, Clinical, And Chronic Disease Factors, Livia Clarete

Dissertations, Theses, and Capstone Projects

This study explores COVID-19 clinical outcomes in Mexico, focusing on demographic, clinical, and chronic disease variables to develop predictive models. In the binary classification task, the Ada Boost Classifier distinguishes survivors from non-survivors, with age, sex, ethnicity, and chronic medical conditions influencing outcomes. In multiclass classification, the Gradient Boosting Classifier categorizes patients into outcome groups.

Demographic variables, especially age, are crucial for predicting COVID-19 outcomes for both the binary and multiclass classification tasks. Clinical information about previous conditions, including chronic diseases, also holds relevance, especially diabetes, immunocompromise, and cardiovascular diseases. These insights inform public health measures and healthcare strategies, emphasizing …

Making Sense Of Making Parole In New York, Alexandra Mcglinchy

Dissertations, Theses, and Capstone Projects

For many individuals incarcerated in New York, the initial step toward freedom begins with an interview with the Board of Parole. This process, however, is frequently a complex and challenging one, characterized by repeated denials and extended incarcerations. The disparity in outcomes – where one individual may receive over 20 denials and another is granted parole on their first attempt – highlights the ambiguity and inconsistency in the parole decision-making process. This project aims to clarify the factors that influence parole decisions by concentrating on measurable variables. These include age, race, duration of sentence served, proportion of sentence served, type …

Analyzing Relationships With Machine Learning, Oscar Ko

Dissertations, Theses, and Capstone Projects

Procedurally, this project aims to take a dataset, analyze it, and offer insights to the audience in an easy-to-digest format. Conceptually, this project will seek to explore questions like: “Do couples that meet through online dating or dating apps have higher or lower quality relationships?”, “Can any features in this dataset help predict how a subject would rate their relationship quality?”, and “What other insights can I derive from using machine learning for exploratory analysis?” The intended audience for this project is anyone interested in romantic relationships or machine learning.

The dataset is from a Stanford University survey, “How Couples …

Semi-Supervised Regression With Generative Adversarial Networks Using Minimal Labeled Data, Greg Olmschenk

Dissertations, Theses, and Capstone Projects

This work studies the generalization of semi-supervised generative adversarial networks (GANs) to regression tasks. A novel feature layer contrasting optimization function, in conjunction with a feature matching optimization, allows the adversarial network to learn from unannotated data and thereby reduce the number of labels required to train a predictive network. An analysis of simulated training conditions is performed to explore the capabilities and limitations of the method. In concert with the semi-supervised regression GANs, an improved label topology and upsampling technique for multi-target regression tasks are shown to reduce data requirements. Improvements are demonstrated on a wide variety of vision …

Assessing The Ordinality Of Response Bias With Item Response Models: A Case Study Using The Phq-9, Venessa N. Singhroy

Dissertations, Theses, and Capstone Projects

Improper scale usage in psychological and clinical assessment is an important problem. If respondents do not use the scales in a consistent manner, the reliability of a composite is likely to be attenuated. This is particularly problematic when particular items are singled out for special treatment or when subscales are of interest, not just a total score. This study used both non-parametric and parametric item response theory (IRT) methods to gain further insight into the validity of the PHQ-9, a dual purpose instrument that assesses the severity of depressive symptoms using nine Likert-scale items and allows the investigator to establish …

Physical Applications Of The Geometric Minimum Action Method, George L. Poppe Jr.

Dissertations, Theses, and Capstone Projects

This thesis extends the landscape of rare events problems solved on stochastic systems by means of the \textit{geometric minimum action method} (gMAM). These include partial differential equations (PDEs) such as the real Ginzburg-Landau equation (RGLE), the linear Schroedinger equation, along with various forms of the nonlinear Schroedinger equation (NLSE) including an application towards an ultra-short pulse mode-locked laser system (MLL).

Additionally we develop analytical tools that can be used alongside numerics to validate those solutions. This includes the use of instanton methods in deriving state transitions for the linear Schroedinger equation and the cubic diffusive NLSE.

These analytical solutions are …