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Full-Text Articles in Statistical Models
Multiscale Modelling Of Brain Networks And The Analysis Of Dynamic Processes In Neurodegenerative Disorders, Hina Shaheen
Multiscale Modelling Of Brain Networks And The Analysis Of Dynamic Processes In Neurodegenerative Disorders, Hina Shaheen
Theses and Dissertations (Comprehensive)
The complex nature of the human brain, with its intricate organic structure and multiscale spatio-temporal characteristics ranging from synapses to the entire brain, presents a major obstacle in brain modelling. Capturing this complexity poses a significant challenge for researchers. The complex interplay of coupled multiphysics and biochemical activities within this intricate system shapes the brain's capacity, functioning within a structure-function relationship that necessitates a specific mathematical framework. Advanced mathematical modelling approaches that incorporate the coupling of brain networks and the analysis of dynamic processes are essential for advancing therapeutic strategies aimed at treating neurodegenerative diseases (NDDs), which afflict millions of …
A Bayesian Programming Approach To Car-Following Model Calibration And Validation Using Limited Data, Franklin Abodo
A Bayesian Programming Approach To Car-Following Model Calibration And Validation Using Limited Data, Franklin Abodo
FIU Electronic Theses and Dissertations
Traffic simulation software is used by transportation researchers and engineers to design and evaluate changes to roadway networks. Underlying these simulators are mathematical models of microscopic driver behavior from which macroscopic measures of flow and congestion can be recovered. Many models are intended to apply to only a subset of possible traffic scenarios and roadway configurations, while others do not have any explicit constraint on their applicability. Work zones on highways are one scenario for which no model invented to date has been shown to accurately reproduce realistic driving behavior. This makes it difficult to optimize for safety and other …
Point Process Modelling Of Objects In The Star Formation Complexes Of The M33 Galaxy, Dayi Li
Point Process Modelling Of Objects In The Star Formation Complexes Of The M33 Galaxy, Dayi Li
Electronic Thesis and Dissertation Repository
In this thesis, Gibbs point process (GPP) models are constructed to study the spatial distribution of objects in the star formation complexes of the M33 galaxy. The GPP models circumvent the limitations of the two-point correlation function employed in the current astronomy literature by naturally accounting for the inhomogeneous distribution of these objects. The spatial distribution of these objects serves as a sensitive probe in understanding the star formation process, which is crucial in understanding the formation of galaxies and the Universe. The objects under study include the CO filament structure, giant molecular clouds (GMCs) and young stellar cluster candidates …
Bayesian Analysis For The Intraclass Model And For The Quantile Semiparametric Mixed-Effects Double Regression Models, Duo Zhang
Dissertations, Master's Theses and Master's Reports
This dissertation consists of three distinct but related research projects. The first two projects focus on objective Bayesian hypothesis testing and estimation for the intraclass correlation coefficient in linear models. The third project deals with Bayesian quantile inference for the semiparametric mixed-effects double regression models. In the first project, we derive the Bayes factors based on the divergence-based priors for testing the intraclass correlation coefficient (ICC). The hypothesis testing of the ICC is used to test the uncorrelatedness in multilevel modeling, and it has not well been studied from an objective Bayesian perspective. Simulation results show that the two sorts …
Ordinal Probit Wavelet-Based Functional Models For Eqtl Analysis, Mark J. Meyer, Jeffrey S. Morris, Craig P. Hersh, Jarret D. Morrow, Christoph Lange, Brent A. Coull
Ordinal Probit Wavelet-Based Functional Models For Eqtl Analysis, Mark J. Meyer, Jeffrey S. Morris, Craig P. Hersh, Jarret D. Morrow, Christoph Lange, Brent A. Coull
Jeffrey S. Morris
Current methods for conducting expression Quantitative Trait Loci (eQTL) analysis are limited in scope to a pairwise association testing between a single nucleotide polymorphism (SNPs) and expression probe set in a region around a gene of interest, thus ignoring the inherent between-SNP correlation. To determine association, p-values are then typically adjusted using Plug-in False Discovery Rate. As many SNPs are interrogated in the region and multiple probe-sets taken, the current approach requires the fitting of a large number of models. We propose to remedy this by introducing a flexible function-on-scalar regression that models the genome as a functional outcome. The …