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Biostatistics Commons™

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Selected Works

2018

Public Health

Articles 1 - 4 of 4

Full-Text Articles in Biostatistics

Aggressive Diuresis And Severity-Adjusted Length Of Hospital Stay In Acute Congestive Heart Failure Patients., Muhammad U. Butt M.D. Apr 2018

Aggressive Diuresis And Severity-Adjusted Length Of Hospital Stay In Acute Congestive Heart Failure Patients., Muhammad U. Butt M.D.

Muhammad Umer Butt M.D., MSCRD

To see if aggressive diuresis in 1st 24 hours is associated with a comparable number of total days in the hospital as compared to non-aggressive diuresis.  In this retrospective cohort study, we compared the length of hospital stay of consecutive patients admitted in one year based on their diuresis during the first twenty-four hours of hospitalization: aggressive diuresis (group 1) i.e. >2400mL versus non-aggressive diuresis (group 2) i.e. ≤ 2400mL urine output. Patients were excluded if in cardiogenic shock, had creatinine level above 3 mg/dL on admission, or on dialysis. A total of 194 patients were enrolled (29 in group …

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Predictors Of Neonatal Abstinence Syndrome In Buprenorphine Exposed Newborn: Can Cord Blood Buprenorphine Metabolite Levels Help?, Darshan Shah, Stacy Brown, Nick Hagemeier, Shimin Zheng, Amy Kyle, Jason Pryor, Nilesh Dankhara, Piyuesh Singh Feb 2018

Predictors Of Neonatal Abstinence Syndrome In Buprenorphine Exposed Newborn: Can Cord Blood Buprenorphine Metabolite Levels Help?, Darshan Shah, Stacy Brown, Nick Hagemeier, Shimin Zheng, Amy Kyle, Jason Pryor, Nilesh Dankhara, Piyuesh Singh

Nicholas E. Hagemeier

Background

Buprenorphine is a semi-synthetic opioid used for the treatment of opioid dependence. Opioid use, including buprenorphine, has been increasing in recent years, in the general population and in pregnant women. Consequently, there has been a rise in frequency of neonatal abstinence syndrome (NAS), associated with buprenorphine use during pregnancy. The purpose of this study was to investigate correlations between buprenorphine and buprenorphine-metabolite concentrations in cord blood and onset of NAS in buprenorphine exposed newborns.

Methods

Nineteen (19) newborns who met inclusion criteria were followed after birth until discharge in a double-blind non-intervention study, after maternal consent. Cord blood and …

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Characterization Of Plasmodium Falciparum And Plasmodium Vivax Recent Exposure In An Area Of Significantly Decreased Transmission Intensity In Central Vietnam, Johanna Helena Kattenberg, Annette Erhart, Minh Hieu Truong, Eduard Rovira-Vallbona, Khac Anh Dung Vu, Thi Hong Ngoc Nguyen, Van Hong Nguyen, Van Van Nguyen, Melanie Bannister-Tyrrell, Michael Theisen, Adam Bennet, Andrew A. Lover, Thanh Duong Tran, Xuan Xa Nguyen, Anna Rosanas-Urgell Dec 2017

Characterization Of Plasmodium Falciparum And Plasmodium Vivax Recent Exposure In An Area Of Significantly Decreased Transmission Intensity In Central Vietnam, Johanna Helena Kattenberg, Annette Erhart, Minh Hieu Truong, Eduard Rovira-Vallbona, Khac Anh Dung Vu, Thi Hong Ngoc Nguyen, Van Hong Nguyen, Van Van Nguyen, Melanie Bannister-Tyrrell, Michael Theisen, Adam Bennet, Andrew A. Lover, Thanh Duong Tran, Xuan Xa Nguyen, Anna Rosanas-Urgell

Andrew Lover

Background
In Vietnam, malaria transmission has been reduced to very low levels over the past 20 years, and as a consequence, the country aims to eliminate malaria by 2030. This study aimed to characterize the dynamics and extent of the parasite reservoir in Central Vietnam, in order to further target elimination strategies and surveillance.
Methods
A 1-year prospective cohort study (n = 429) was performed in three rural communities in Quang Nam province. Six malaria screenings were conducted between November 2014 and November 2015, including systematic clinical examination and blood sampling for malaria parasite identification, as well as molecular and serological …

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Malaria Elimination: Time To Target All Species, Andrew A. Lover, J. Kevin Baird, Roly Gosling, Ric N. Price Dec 2017

Malaria Elimination: Time To Target All Species, Andrew A. Lover, J. Kevin Baird, Roly Gosling, Ric N. Price

Andrew Lover

Important strides have been made within the past decade toward malaria elimination in many regions, and with this progress, the feasibility of eradication is once again under discussion. If the ambitious goal of eradication is to be achieved by 2040, all species of Plasmodium infecting humans will need to be targeted with evidence-based and concerted interventions. In this perspective, the potential barriers to achieving global malaria elimination are discussed with respect to the related diversities in host, parasite, and vector populations. We argue that control strategies need to be reorientated from a sequential attack on each species, dominated by Plasmodium …

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