Biostatistics Commons^™

A Math Research Project Inspired By Twin Motherhood, Tiffany N. Kolba

Tiffany N Kolba

The phenomenon of twins, triplets, quadruplets, and other higher order multiples has fascinated humans for centuries and has even captured the attention of mathematicians who have sought to model the probabilities of multiple births. However, there has not been extensive research into the phenomenon of polyovulation, which is one of the biological mechanisms that produces multiple births. In this paper, I describe how my own experience becoming a mother to twins led me on a quest to better understand the scientific processes going on inside my own body and motivated me to conduct research on polyovulation frequencies. An overview of …

Aggressive Diuresis And Severity-Adjusted Length Of Hospital Stay In Acute Congestive Heart Failure Patients., Muhammad U. Butt M.D.

Muhammad Umer Butt M.D., MSCRD

Integrated Bioinformatics, Environmental Epidemiologic And Genomic Approaches To Identify Environmental And Molecular Links Between Endometriosis And Breast Cancer, Deodutta Roy, Marisa L. Morgan, Changwon Yoo, Alok Deoraj, Sandhya Roy, Vijay Kumar Yadav, Mohannad Garoub, Hamza Assaggaf, Mayur Doke

Alok Deoraj

We present a combined environmental epidemiologic, genomic, and bioinformatics approach to identify: exposure of environmental chemicals with estrogenic activity; epidemiologic association between endocrine disrupting chemical (EDC) and health effects, such as, breast cancer or endometriosis; and gene-EDC interactions and disease associations. Human exposure measurement and modeling confirmed estrogenic activity of three selected class of environmental chemicals, polychlorinated biphenyls (PCBs), bisphenols (BPs), and phthalates. Meta-analysis showed that PCBs exposure, not Bisphenol A (BPA) and phthalates, increased the summary odds ratio for breast cancer and endometriosis. Bioinformatics analysis of gene-EDC interactions and disease associations identified several hundred genes that were altered by …

Predictors Of Neonatal Abstinence Syndrome In Buprenorphine Exposed Newborn: Can Cord Blood Buprenorphine Metabolite Levels Help?, Darshan Shah, Stacy Brown, Nick Hagemeier, Shimin Zheng, Amy Kyle, Jason Pryor, Nilesh Dankhara, Piyuesh Singh

Nicholas E. Hagemeier

Background

Buprenorphine is a semi-synthetic opioid used for the treatment of opioid dependence. Opioid use, including buprenorphine, has been increasing in recent years, in the general population and in pregnant women. Consequently, there has been a rise in frequency of neonatal abstinence syndrome (NAS), associated with buprenorphine use during pregnancy. The purpose of this study was to investigate correlations between buprenorphine and buprenorphine-metabolite concentrations in cord blood and onset of NAS in buprenorphine exposed newborns.

Methods

Nineteen (19) newborns who met inclusion criteria were followed after birth until discharge in a double-blind non-intervention study, after maternal consent. Cord blood and …

A Ten-Year Comparison Of Women Authorship In U.S. Dermatology Literature, 1999 Vs. 2009, Shali Zhang, Ha-Young Kim, Rachel E.S. Hill, Emir Veledar, Suephy C. Chen

Emir Veledar

Women are entering medicine at increasing rates, particularly in dermatology. In this study, we compared women’s influence and status in academic dermatology with that of men by examining authorship roles in peer-reviewed dermatology literature.Weexamined the literature in2009 and compared that to10 years prior (1999).Atotal of 1399 articles were reviewed, 594 of whichmet study criteria andwere included in statistical analysis. There was amarked increase in senior female authorship over a decade (22% vs. 38%, p b 0.001). Female first authorship increased as well (41% vs. 51%, p b 0.001). In contrast, changes in male senior and first authorship were not statistically …

Characterization Of Plasmodium Falciparum And Plasmodium Vivax Recent Exposure In An Area Of Significantly Decreased Transmission Intensity In Central Vietnam, Johanna Helena Kattenberg, Annette Erhart, Minh Hieu Truong, Eduard Rovira-Vallbona, Khac Anh Dung Vu, Thi Hong Ngoc Nguyen, Van Hong Nguyen, Van Van Nguyen, Melanie Bannister-Tyrrell, Michael Theisen, Adam Bennet, Andrew A. Lover, Thanh Duong Tran, Xuan Xa Nguyen, Anna Rosanas-Urgell

Andrew Lover

Malaria Elimination: Time To Target All Species, Andrew A. Lover, J. Kevin Baird, Roly Gosling, Ric N. Price

Andrew Lover