Statistics and Probability Commons^™

Jmasm11: Comparing Two Small Binomial Proportions, James F. Reed Iii

Journal of Modern Applied Statistical Methods

A large volume of research has focused on comparing the difference between two small binomial proportions. Statisticians recognize that Fisher’s Exact test and Yates chi-square test are excessively conservative. Likewise, many statisticians feel that Pearson’s Chi-square or the likelihood statistic may be inappropriate for small samples. Viable alternatives exist.

A Test-Retest Transition Matrix: A Modification Of Mcnemar’S Test, J. Wanzer Drane, W. Gregory Thatcher

Journal of Modern Applied Statistical Methods

McNemar introduced what is known today as a test for symmetry in a two by two contingency tables. The logic of the test is based on a sample of matched pairs with a dichotomous response. In our example, the sample consists of the scores before and after an education program and the responses before and after the program. Each pair of scores is from only one person. The pretest divides the group of responders according to their answers to a dichotomous question. The posttest divides the two groups into two groups of like labels. The result is a two by …

On The Reporting Of Reliability In Content Analysis, Patric R. Spence

Journal of Modern Applied Statistical Methods

This article explores one type of misreporting of reliability that has been seen in recent conference papers and articles using the method of content analysis. The reporting of reliability is central to the validity of claims made using this method. A brief overview of content analysis is offered, followed by the exploration of one type of misreporting of reliability. Suggestions are offered to address the problem.

Validation Studies: Matters Of Dimensionality, Accuracy, And Parsimony With Predictive Discriminant Analysis And Factor Analysis, David A. Walker

Journal of Modern Applied Statistical Methods

Two studies were used as examples that examined issues of dimensionality, accuracy, and parsimony in educational research via the use of predictive discriminant analysis and factor analysis. Using a two-group problem, study 1 looked at how accurately group membership could be predicted from subjects’ test scores. Study 2 looked at the dimensionality structure of an instrument and if it developed constructs that would measure theorized domains.

Stratified Extreme Ranked Set Sample With Application To Ratio Estimators, Hani M. Samawai, Laith J. Saeid

Journal of Modern Applied Statistical Methods

Stratified extreme ranked set sample (SERSS) is introduced. The performance of the combined and separate ratio estimates using SERSS is investigated. Theoretical and simulation study are presented. Results indicate that using SERSS for estimating the ratios is more efficient than using stratified simple random sample (SSRS) and simple random sample (SRS). In some cases it is more efficient than ranked set sample (RSS) and stratified ranked set sample (SRSS), when the underlying distribution is symmetric. An application to real data on the bilirubin level in jaundice babies is introduced to illustrate the method.

Depth Based Permutation Test For General Differences In Two Multivariate Populations, Yonghong Gao

Journal of Modern Applied Statistical Methods

For two p-dimensional data sets, interest exists in testing if they come from the common population distribution. Proposed is a practical, effective and easy to implement procedure for the testing problem. The proposed procedure is a permutation test based on the concept of the depth of one observation relative to some population distribution. The proposed test is demonstrated to be consistent. A small Monte Carlo simulation was conducted to evaluate the power of the proposed test. The proposed test is applied to some numerical examples.

Accurate Binary Decisions For Assessing Coronary Artery Disease, Mehmet Ali Cengiz

Journal of Modern Applied Statistical Methods

Generalized linear models offer convenient and highly applicable tools for modeling and predicting the behavior of random variables in terms of observable factors and covariates. This paper investigates applications of a special case of generalized linear model to improve the accuracy of predictions and decisions adopting Bayesian methods, in the specific context of assessing coronary artery disease. The basic model is developed for this application using binary response. The results clearly demonstrate the potential advantages offered by this approach.

Statistical Pronouncements Iii, Jmasm Editors

Journal of Modern Applied Statistical Methods

No abstract provided.

Meta-Analysis Of Results And Individual Patient Data In Epidemiologal Studies, Aurelio Tobías, Marc Saez, Manolis Kogevinas

Journal of Modern Applied Statistical Methods

Epidemiological information can be aggregated by combining results through a meta-analysis technique, or by pooling and analyzing primary data. Common approaches to analyzing pooled studies through an example on the effect of occupational exposure to wood dust on sinonasal cancer are described. Results were combined applying a meta-analysis technique. Alternatively, primary data from all studies were pooled and re-analyzed using mixed effect models. The combination of individual information rather than results is desirable to facilitate interpretations of epidemiological findings, leading also to more precise estimations and more powerful statistical tests for study heterogeneity.

Multivariate Location: Robust Estimators And Inference, Rand R. Wilcox, H. J. Keselman

Journal of Modern Applied Statistical Methods

The sample mean can have poor efficiency relative to various alternative estimators under arbitrarily small departures from normality. In the multivariate case, (affine equivariant) estimators have been proposed for dealing with this problem, but a comparison of various estimators by Massé and Plante (2003) indicated that the small-sample efficiency of some recently derived methods is rather poor. This article reports that a skipped mean, where outliers are removed via a projection-type outlier detection method, is found to be more satisfactory. The more obvious method for computing a confidence region based on the skipped estimator (using a slight modification of the …

A Power Comparison Of Robust Test Statistics Based On Adaptive Estimators, H. J. Keselman, Rand R. Wilcox, James Algina, Abdul R. Othman

Journal of Modern Applied Statistical Methods

Seven test statistics known to be robust to the combined effects of nonnormality and variance heterogeneity were compared for their sensitivity to detect treatment effects in a one-way completely randomized design containing four groups. The six Welch-James-type heteroscedastic tests adopted either symmetric or asymmetric trimmed means, were transformed for skewness, and used a bootstrap method to assess statistical significance. The remaining test, due to Wilcox and Keselman (2003), used a modification of the well-known one-step M-estimator of central tendency rather than trimmed means. The Welch-James-type test is recommended because for nonnormal data likely to be encountered in applied research settings …

A Rank-Based Estimation Procedure For Linear Models With Clustered Data, Suzanne R. Dubnicka

Journal of Modern Applied Statistical Methods

A rank method is presented for estimating regression parameters in the linear model when observations are correlated. This correlation is accounted for by including a random effect term in the linear model. A method is proposed that makes few assumptions about the random effect and error distribution. The main goal of this article is to determine the distributions for which this method performs well relative to existing methods.

A Generalized Quasi-Likelihood Model Application To Modeling Poverty Of Asian American Women, Jeffrey R. Wilson

Journal of Modern Applied Statistical Methods

A generalized quasi-likelihood function that does not require the assumption of an underlying distribution when modeling jointly the mean and the variance, is introduced to examine poverty of Asian American women living in the West coast of the United States, using data from U.S. Census Bureau.

Estimation Of Multiple Linear Functional Relationships, Amjad D. Al-Nasser

Journal of Modern Applied Statistical Methods

This article deals with multiple linear functional relationships models. Two robust estimations procedure are proposed to estimate the model, based on Generalized Maximum Entropy and Partial Least Square. They are distribution free and do not rely (so much) on classical assumptions. The experiments showed that the GME approach outperforms the PLS in terms of mean squares of errors (MSE). Empirical examples are studied.

Teaching Random Assignment: Do You Believe It Works?, Shlomo S. Sawilowsky

Journal of Modern Applied Statistical Methods

Textbook authors admonish students to check on the comparability of two randomly assigned groups by conducting statistical tests on pretest means to determine if randomization worked. A Monte Carlo study was conducted on a sample of n = 2 per group, where each participant’s personality profile was represented by 7,500 randomly selected and assigned scores. Independent samples t tests were conducted and the results demonstrated that random assignment was successful in equating the two groups on 7,467 variables. The students’ focus is redirected from the ability of random assignment to create comparable groups to the testing of the claims of …

A Comparison Of Bayesian And Frequentist Statistics As Applied In A Simple Repeated Measures Example, Jan Perkins, Daniel Wang

Journal of Modern Applied Statistical Methods

Clinicians see Bayesian and frequentist analysis in published research papers, and need a basic understanding of both. A repeated measures data set was analyzed using both approaches. Assumptions underlying each method and conclusions reached were contrasted. The Bayesian approach is a viable alternative to frequentist statistical analysis for many clinical projects.

Jmasm10: A Fortran Routine For Sieve Bootstrap Prediction Intervals, Andrés M. Alonso

Journal of Modern Applied Statistical Methods

A Fortran routine for constructing nonparametric prediction intervals for a general class of linear processes is described. The approach uses the sieve bootstrap procedure of Bühlmann (1997) based on residual resampling from an autoregressive approximation to the given process.

A Resistant Estimator Of Multivariate Location And Dispersion, David J. Olive

Articles and Preprints

This paper presents a simple resistant estimator of multivariate location and dispersion. The DD plot is a plot of Mahalanobis distances from the classical estimator versus the distances from a resistant estimator and can be used to detect outliers and as a diagnostic for multivariate normality. The new estimator can be used in the DD plot, is easy to compute and provides insights about several useful robust algorithm techniques.

A Comparison Of Methods For Longitudinal Analysis With Missing Data, James Algina, H. J. Keselman

Journal of Modern Applied Statistical Methods

In a longitudinal two-group randomized trials design, also referred to as randomized parallel-groups design or split-plot repeated measures design, the important hypothesis of interest is whether there are differential rates of change over time, that is, whether there is a group by time interaction. Several analytic methods have been presented in the literature for testing this important hypothesis when data are incomplete. We studied these methods for the case in which the missing data pattern is non-monotone. In agreement with earlier work on monotone missing data patterns, our results on bias, sampling variability, Type I error and power support the …

On Polynomial Transformations For Simulating Multivariate Non-Normal Distributions, Todd C. Headrick

Journal of Modern Applied Statistical Methods

Procedures are introduced and discussed for increasing the computational and statistical efficiency of polynomial transformations used in Monte Carlo or simulation studies. Comparisons are also made between polynomials of order three and five in terms of (a) computational and statistical efficiency, (b) the skew and kurtosis boundary, and (c) boundaries for Pearson correlations. It is also shown how ranked data can be simulated for specified Spearman correlations and sample sizes. Potential consequences of nonmonotonic transformations on rank correlations are also discussed.

An Alternative Q Chart Incorporating A Robust Estimator Of Scale, Michael B. C. Khoo

Journal of Modern Applied Statistical Methods

In overcoming the shortcomings of the classical control charts in a short runs production, Quesenberry (1991 & 1995a – d) proposed Q charts for attributes and variables data. An approach to enhance the performance of a variable Q chart based on individual measurements using a robust estimator of scale is proposed. Monte carlo simulations are conducted to show that the proposed robust Q chart is superior to the present Q chart.

Quantifying The Proportion Of Cases Attributable To An Exposure, Camil Fuchs, Vance W. Berger

Journal of Modern Applied Statistical Methods

The attributable fraction and the average attributable fractions, which are commonly used to assess the relative effect of several exposures to the prevalence of a disease, do not represent the proportion of cases caused by each exposure. Furthermore, the sum of attributable fractions over all exposures generally exceeds not only the attributable fraction for all exposures taken together, but also 100%. Other measures are discussed here, including the directly attributable fraction and the confounding fraction, that may be more suitable in defining the fraction directly attributable to an exposure.

The Robustness Of Factor Analyses When The Data Does Not Conform To Standard Parametric Requirements, Haisong Peng

All Graduate Plan B and other Reports, Spring 1920 to Spring 2023

Objective: To access the robustness of factor analyses when the data does not conform to standard parametric requirements.

Methods: Data were simulated in package R. Maximum likelihood was used to fit and assess the factor models. Chi-square statistics were obtained to test hypotheses about the correct number of factors in simulated settings where the true number of factors was known. The number of true factors varied between 1 and 3; the number of observed variables was either 6 (for 1 factor) or 3 per factor for 2 or more factors.

Results: With standard normal factor populations, and normal errors added …

Does Weighting For Nonresponse Increase The Variance Of Survey Means?, Rod Little, Sonya L. Vartivarian

The University of Michigan Department of Biostatistics Working Paper Series

Nonresponse weighting is a common method for handling unit nonresponse in surveys. A widespread view is that the weighting method is aimed at reducing nonresponse bias, at the expense of an increase in variance. Hence, the efficacy of weighting adjustments becomes a bias-variance trade-off. This note suggests that this view is an oversimplification -- nonresponse weighting can in fact lead to a reduction in variance as well as bias. A covariate for a weighting adjustment must have two characteristics to reduce nonresponse bias - it needs to be related to the probability of response, and it needs to be related …

Resampling Methods For Estimating Functions With U-Statistic Structure, Wenyu Jiang, Jack Kalbfleisch

The University of Michigan Department of Biostatistics Working Paper Series

Suppose that inference about parameters of interest is to be based on an unbiased estimating function that is U-statistic of degree 1 or 2. We define suitable studentized versions of such estimating functions and consider asymptotic approximations as well as an estimating function bootstrap (EFB) method based on resampling the estimated terms in the estimating functions. These methods are justified asymptotically and lead to confidence intervals produced directly from the studentized estimating functions. Particular examples in this class of estimating functions arise in La estimation as well as Wilcoxon rank regression and other related estimation problems. The proposed methods are …

One- And Two-Sample Nonparametric Inference Procedures In The Presence Of Dependent Censoring, Yuhyun Park, Lu Tian, L. J. Wei

Harvard University Biostatistics Working Paper Series

No abstract provided.

Covariate Adjustment In The Analysis Of Microarray Data From Clinical Studies, Debashis Ghosh, Arul Chinnaiyan

The University of Michigan Department of Biostatistics Working Paper Series

There is tremendous scientific interest in the analysis of gene expression data in clinical settings, such as oncology. In this paper, we describe the importance of adjusting for confounders and other prognostic factors in order to select for differentially expressed genes for followup validation studies. We develop two approaches to the analysis of microarray data in nonrandomized clinical settings. The first is an extension of the current significance analysis of microarray procedures, where other covariates are taken into account. The second is a novel covariate-adjusted regression modelling based on the receiver operating characteristic curve for the analysis of gene expression …

Evaluating Markers For Selecting A Patient's Treatment, Xiao Song, Margaret S. Pepe

UW Biostatistics Working Paper Series

Selecting the best treatment for a patient's disease may be facilitated by evaluating clinical characteristics or biomarker measurements at diagnosis. We consider how to evaluate the potential of such measurements to impact on treatment selection algorithms. For example, magnetic resonance neurographic imaging is potentially useful for deciding whether a patient should be treated surgically for carpal tunnel syndrome or if he/she should receive less invasive conservative therapy. We propose a graphical display, the selection impact (SI) curve, that shows the population response rate as a function of treatment selection criteria based on the marker. The curve can be useful for …

Nonparametric Control Chart For The Range, Arnold J. Stromberg

Statistics Faculty Patents

The method comprises establishing the number of subsets of a dataset that have a range of the difference between any two datapoints within the dataset, and computing a control chart for the range based thereon. In another aspect, a software program for accomplishing the method of the present invention is provided. The method of the invention allows monitoring variability of a product being produced by a particular piece of machinery, of a process conducted by the machinery, or of a product stream generated thereby, accurately detecting changes in variability in real time. The true distribution of the data is reflected, …

Mathematical And Empirical Modeling Of Chemical Reactions In A Microreactor, Jing Hu

Doctoral Dissertations

This dissertation is concerned with mathematical and empirical modeling to simulate three important chemical reactions (cyclohexene hydrogenation and dehydrogenation, preferential oxidation of carbon monoxide, and the Fischer-Tropsch (F-T) synthesis in a microreaction system.

Empirical modeling and optimization techniques based on experimental design (Central Composite Design (CCD)) and response surface methodology were applied to these three chemical reactions. Regression models were built, and the operating conditions (such as temperature, the ratio of the reactants, and total flow rate) which maximize reactant conversion and product selectivity were determined for each reaction.

A probability model for predicting the probability that a certain species …