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Full-Text Articles in Statistics and Probability

How 6-12th Grade Staff Support Students With Depression: A Pilot Study To Develop Measures Of Implicit Associations, Explicit Attitudes And Helping Behavior, Paul M. Thompson Jan 2020

How 6-12th Grade Staff Support Students With Depression: A Pilot Study To Develop Measures Of Implicit Associations, Explicit Attitudes And Helping Behavior, Paul M. Thompson

Electronic Theses and Dissertations

Students with emotional disabilities are disproportionately suspended and expelled in K-12 schools. Attribution theory suggests individuals are less likely to provide assistance to others if they believe the individuals are responsible for their own difficulties. To test attribution theory, this study created new measures of explicit attitudes and implicit associations of licensed 6-12th grade staff regarding students with depression as well as a helping behavior measure of staff toward students with depression. The survey was distributed within a single school district in the western United States. A majority of the sample (N = 52) held a mental health license (60%), …


An Analysis Of The Success Of Farmers Markets In Kentucky Using Logistic Regression And Support Vector Machines, Jeron Russell Jan 2020

An Analysis Of The Success Of Farmers Markets In Kentucky Using Logistic Regression And Support Vector Machines, Jeron Russell

Mahurin Honors College Capstone Experience/Thesis Projects

The purpose of this research is to look at the relationship that market-specific, economic, and demographic variables have with the success of farmers markets in Kentucky. It additionally seeks to build a tool for predicting farmers market success that could be used by policy makers to aid in decision-making processes concerning farmers markets. Logistic regression and Support Vector Machines (SVMs) are used on data acquired from the Kentucky Department of Agriculture and the American Community Survey in order to analyze the data in a traditional statistical approach as well as a machine learning approach. The results included an SVM model …


A Multinational Study Of The Etiology And Clinical Teleology Of Moral Evaluations Of Patient Behaviors, Anna Yu Lee Jan 2020

A Multinational Study Of The Etiology And Clinical Teleology Of Moral Evaluations Of Patient Behaviors, Anna Yu Lee

CGU Theses & Dissertations

This dissertation is a collection of four studies which collectively explore a hypothesized construct of ‘moral evaluation of patient behaviors’ (MEPB) as a driver of health professionals’ readiness to interact humanistically with their patients. In these studies, ‘humanistic interactions’ refer to the non-technical, intangible skills and factors of clinical competence; the factors specifically explored in these studies were compassion toward patients, self-efficacy for treating patients, and optimism toward patient treatment. For the purpose of specificity, all factors were examined as they pertained to patients with substance use disorders. Survey data from a convenience sample of 524 health professionals (i.e. physicians, …


Wage-Productivity Analysis Of U.S. Domestic Airlines, Jesse Lucas, Khairul Azuar, Justin Tan, Syed Ilyas Jan 2020

Wage-Productivity Analysis Of U.S. Domestic Airlines, Jesse Lucas, Khairul Azuar, Justin Tan, Syed Ilyas

Introduction to Research Methods RSCH 202

This study examines the impact of wages on productivity by examining US domestic airlines.

Current literature places emphasis on jobs conducted in-flight, specifically pilots and cabin crew. This paper considers all job titles involved in the operations of the airline, including executives and management. Existing research focuses on factors such as governance, domestic economic level, and personal attributes such as intrinsic motivation, gender, and age. There is insufficient research regarding the relationship between wage and productivity. Thus, it is uncertain if high wage leads to high productivity. Preliminary findings suggest higher wage equates to higher productivity.


Three Essays On Model Selection, Fangning Li Jan 2020

Three Essays On Model Selection, Fangning Li

Legacy Theses & Dissertations (2009 - 2024)

In empirical research, we often need to address the issue of what model to use given a collection of candidate models. Conventionally, we use model selection to choose one best model from the collection of candidate models based on some model selection criteria. Model averaging is a generalization of model selection in the sense that it assigns weights to candidate models and uses a weighted average to construct an aggregated model. Usually model averaging provides better performance than model selection which chooses a single candidate model based on AIC or BIC.


The Economic Determinants Of American Professional Sports Franchise Valuations, Ryan Flora Jan 2020

The Economic Determinants Of American Professional Sports Franchise Valuations, Ryan Flora

Mahurin Honors College Capstone Experience/Thesis Projects

This thesis seeks to analyze the impact of regional identities on American professional sports team valuations. Regional identities are classified as any name of a team that is not tied directly to the city that they reside in. For example, the Carolina Panthers have a regional identity because they are not based out of “Carolina”, they are based out of Charlotte, North Carolina. Another example would be the Arizona Cardinals, whose name encompasses the whole state of Arizona rather than Phoenix, the city they are based out of. The leagues that will be involved in this study are the National …


An Introduction To Copulas, Yifan Guo, Geng Zhang Jan 2020

An Introduction To Copulas, Yifan Guo, Geng Zhang

Capstone Showcase

Copulas are the mathematical functions that connect the distribution functions of univariate random variables to form multivariate distributions. We define copulas, present some of their key properties, and provide examples of their applications.


Accounting For The Uncertainty Due To Chemicals Below The Detection Limit In Mixture Analysis, Paul M. Hargarten Jan 2020

Accounting For The Uncertainty Due To Chemicals Below The Detection Limit In Mixture Analysis, Paul M. Hargarten

Theses and Dissertations

Humans are exposed to multiple chemicals every day. Epidemiological studies have shown that chemical mixtures are associated with cancers, allergies, neurodevelopmental disorders, and other adverse health effects. To assess these associations, investigators are increasingly using chemical mixture approaches like weighted quantile sum (WQS) regression. In these studies, the research objectives are to determine whether a mixture of correlated chemicals is associated with an adverse health outcome and to identify the important chemicals. However, as experimental equipment measures each exposure to a chemical-specific detection limit, the exposures are unknown between zero and the detection limit. Indeed, the number of exposures below …


The Effect Of Time And Temperature On The Quality Of Latent Fingerprints On Incandescent Lightbulbs, Varying Donors Age And Sex, Kinaysha M. Collazo Maldonado Jan 2020

The Effect Of Time And Temperature On The Quality Of Latent Fingerprints On Incandescent Lightbulbs, Varying Donors Age And Sex, Kinaysha M. Collazo Maldonado

Master of Science in Forensic Science Directed Research Projects

Fingerprints are used as a means of identification, but there are no established methodologies to determine time since deposition of latent fingerprints by visual means alone. This research considered the influence of age and sex on the quality of recovered latent prints from lit and unlit lightbulbs from 1 to 10 days, using accumulated degree hours (ADH) to account for both heat and time simultaneously. Two male and two female donors (one of each aged40 years) were used. A thermal imaging camera was used to monitor the lightbulbs top and middle regions, which were significantly different (p≤0.05) for the experimental …


K-Means Stock Clustering Analysis Based On Historical Price Movements And Financial Ratios, Shu Bin Jan 2020

K-Means Stock Clustering Analysis Based On Historical Price Movements And Financial Ratios, Shu Bin

CMC Senior Theses

The 2015 article Creating Diversified Portfolios Using Cluster Analysis proposes an algorithm that uses the Sharpe ratio and results from K-means clustering conducted on companies' historical financial ratios to generate stock market portfolios. This project seeks to evaluate the performance of the portfolio-building algorithm during the beginning period of the COVID-19 recession. S&P 500 companies' historical stock price movement and their historical return on assets and asset turnover ratios are used as dissimilarity metrics for K-means clustering. After clustering, stock with the highest Sharpe ratio from each cluster is picked to become a part of the portfolio. The economic and …


Three Essays On Health Economics And Policy Evaluation, Shishir Shakya Jan 2020

Three Essays On Health Economics And Policy Evaluation, Shishir Shakya

Graduate Theses, Dissertations, and Problem Reports (ETD)

This dissertation consists of three essays on the U.S. Health care policy. Each paragraph below refers to the three abstracts for the three chapters in this dissertation, respectively. I provide quantitative evidence on how much Prescription Drug Monitoring Programs (PDMPs) affects the retail opioid prescribing behaviors. Using the American Community Survey (ACS), I retrieve county-level high dimensional panel data set from 2010 to 2017. I employ three separate identification strategies: difference-in-difference, double selection post-LASSO, and spatial difference-in-difference. I compare how the retail opioid prescribing behaviors of counties, that are mandatory for prescribers to check the PDMP before prescribing controlled substances …


Mass Grave Localization Prediction With Geographical Information Systems In Guatemala And Future Impacts, Perla Santillan Jan 2020

Mass Grave Localization Prediction With Geographical Information Systems In Guatemala And Future Impacts, Perla Santillan

Master of Science in Forensic Science Directed Research Projects

Conducting physical searches for mass grave locations based on anecdotal evidence is a time consuming and resource intensive endeavor in circumstances that often pose a threat to personal safety. The development of tools and procedures to speed such searches can greatly reduce the risk involved, increase the number of individuals whose remains are recovered and identified; and, more importantly, reunite these remains with their loved ones to provide them with a proper burial. Geographic information systems (GIS) software, which can analyze and manipulate the spatial characteristics of known mass grave data, represents a powerful tool that can be used to …


Public Perception Of Different Planting Techniques Using Augmented Reality, Sultana Quader Tania Jan 2020

Public Perception Of Different Planting Techniques Using Augmented Reality, Sultana Quader Tania

College of Graduate Studies: Theses & Dissertations

The objective of this study was to measure public perception of the different planting techniques (block and matrix), which are used at visitor information centers (VICs) and other rights of way (ROW) areas. The main factors that affect public perception of planting techniques were identified through an extensive literature review and qualitative survey from four welcome centers in the state of Georgia. The ranking of those indicators, based on public preferences, was discovered through a quantitative survey. During the first phase of the quantitative survey, images of block and matrix were used. An iOS-based user-friendly and cost-effective augmented reality (AR) …


Phenotype Extraction: Estimation And Biometrical Genetic Analysis Of Individual Dynamics, Kevin L. Mckee Jan 2020

Phenotype Extraction: Estimation And Biometrical Genetic Analysis Of Individual Dynamics, Kevin L. Mckee

Theses and Dissertations

Within-person data can exhibit a virtually limitless variety of statistical patterns, but it can be difficult to distinguish meaningful features from statistical artifacts. Studies of complex traits have previously used genetic signals like twin-based heritability to distinguish between the two. This dissertation is a collection of studies applying state-space modeling to conceptualize and estimate novel phenotypic constructs for use in psychiatric research and further biometrical genetic analysis. The aims are to: (1) relate control theoretic concepts to health-related phenotypes; (2) design statistical models that formally define those phenotypes; (3) estimate individual phenotypic values from time series data; (4) consider hierarchical …


Modelling Interactions Among Offenders: A Latent Space Approach For Interdependent Ego-Networks, Isabella Gollini, Alberto Caimo, Paolo Campana Jan 2020

Modelling Interactions Among Offenders: A Latent Space Approach For Interdependent Ego-Networks, Isabella Gollini, Alberto Caimo, Paolo Campana

Articles

Illegal markets are notoriously difficult to study. Police data offer an increasingly exploited source of evidence. However, their secondary nature poses challenges for researchers. A key issue is that researchers often have to deal with two sets of actors: targeted and non-targeted. This work develops a latent space model for interdependent ego-networks purposely created to deal with the targeted nature of police evidence. By treating targeted offenders as egos and their contacts as alters, the model (a) leverages on the full information available and (b) mirrors the specificity of the data collection strategy. The paper then applies this approach to …


Personalized Detection Of Anxiety Provoking News Events Using Semantic Network Analysis, Jacquelyn Cheun Phd, Luay Dajani, Quentin B. Thomas Dec 2019

Personalized Detection Of Anxiety Provoking News Events Using Semantic Network Analysis, Jacquelyn Cheun Phd, Luay Dajani, Quentin B. Thomas

SMU Data Science Review

In the age of hyper-connectivity, 24/7 news cycles, and instant news alerts via social media, mental health researchers don't have a way to automatically detect news content which is associated with triggering anxiety or depression in mental health patients. Using the Associated Press news wire, a semantic network was built with 1,056 news articles containing over 500,000 connections across multiple topics to provide a personalized algorithm which detects problematic news content for a given reader. We make use of Semantic Network Analysis to surface the relationship between news article text and anxiety in readers who struggle with mental health disorders. …


Implications Of The Modifiable Areal Unit Problem For Wildfire Analyses, Timothy P. Nagle-Mcnaughton, Xi Gong, Jose A. Constantine Dec 2019

Implications Of The Modifiable Areal Unit Problem For Wildfire Analyses, Timothy P. Nagle-Mcnaughton, Xi Gong, Jose A. Constantine

Geography and Environmental Studies Faculty Publications

Wildfires pose a danger to both ecologies and communities. To this end, many large-scale analyses of wildfire patterns and behavior rely on the aggregation of point data to polygons, typically those based on distinct disparate ecological areas. However, the sizes, shapes, andorientations of the polygons to which data are aggregated are not neutral factors in the resulting analysis. The influence of the aggregation polygons on calculated results is known as the modifiable areal unit problem (MAUP), which is well-documented in the spatial statistics literature. Despite the documentation of the MAUP, relatively few wildfire studies consider the effects of the MAUP …


Evaluation Of Modern Missing Data Handling Methods For Coefficient Alpha, Katerina Matysova Dec 2019

Evaluation Of Modern Missing Data Handling Methods For Coefficient Alpha, Katerina Matysova

College of Education and Human Sciences: Dissertations, Theses, and Student Research

When assessing a certain characteristic or trait using a multiple item measure, quality of that measure can be assessed by examining the reliability. To avoid multiple time points, reliability can be represented by internal consistency, which is most commonly calculated using Cronbach’s coefficient alpha. Almost every time human participants are involved in research, there is missing data involved. Missing data means that even though complete data were expected to be collected, some data are missing. Missing data can follow different patterns as well as be the result of different mechanisms. One traditional way to deal with missing data is listwise …


Communications And Methodologies In Crime Geography: Contemporary Approaches To Disseminating Criminal Incidence And Research, Mitchell Ogden Dec 2019

Communications And Methodologies In Crime Geography: Contemporary Approaches To Disseminating Criminal Incidence And Research, Mitchell Ogden

Electronic Theses and Dissertations

Many tools exist to assist law enforcement agencies in mitigating criminal activity. For centuries, academics used statistics in the study of crime and criminals, and more recently, police departments make use of spatial statistics and geographic information systems in that pursuit. Clustering and hot spot methods of analysis are popular in this application for their relative simplicity of interpretation and ease of process. With recent advancements in geospatial technology, it is easier than ever to publicly share data through visual communication tools like web applications and dashboards. Sharing data and results of analyses boosts transparency and the public image of …


Using A Discrete Choice Experiment To Estimate Willingness To Pay For Location Based Housing Attributes, Kristopher C. Toll Dec 2019

Using A Discrete Choice Experiment To Estimate Willingness To Pay For Location Based Housing Attributes, Kristopher C. Toll

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

In 1993, a travel study was conducted along the Wasatch front in Utah (Research Systems Group INC, 2013). The main purpose of this study was to assess travel behavior to understand the needs for future growth in Utah. Since then, the Research Service Group (RSG), conducted a new study in 2012 to understand current travel preferences in Utah. This survey, called the Residential Choice Stated Preference survey, asked respondents to make ten choice comparisons between two hypothetical homes. Each home in the choice comparison was described by different attributes, those attributes that were used are, type of neighborhood, distance from …


Effect Of Self-Regulated Learning For Improving Dietary Management And Quality Of Life In Patients With Type-2 Diabetes Mellitus At Dr. Ramelan Naval Hospital, Surabaya, Indonesia, Yayuk Estuningsih, Thinni Nurul Rochmah, Merryana Andriani, Trias Mahmudiono Nov 2019

Effect Of Self-Regulated Learning For Improving Dietary Management And Quality Of Life In Patients With Type-2 Diabetes Mellitus At Dr. Ramelan Naval Hospital, Surabaya, Indonesia, Yayuk Estuningsih, Thinni Nurul Rochmah, Merryana Andriani, Trias Mahmudiono

Kesmas

Self-regulated learning is a process of learning how to manage and regulate oneself to obtain skills and knowledge without depending on others. It is expected that diabetes patients can manage their diabetes by themselves. This study aimed to analyze the effect of self-regulated learning-based educational intervention on quality of life for patients with type-2 diabetes mellitus (DM) at Dr. Ramelan Naval Hospital, Surabaya. This was a quasi-experimental study in the form of pretest and posttest with a control group design. A total of 20 patients with DM were randomly divided into intervention and control groups to undergo a 4-week intervention. …


Maternal Knowledge, Attitude, And Practices About Traditional Food Feeding With Stunting And Wasting Of Toddlers In Farmer Families, Betty Yosephin Simanjuntak, Miratul Haya, Desri Suryani, Ali Khomsan, Che An Ahmad Nov 2019

Maternal Knowledge, Attitude, And Practices About Traditional Food Feeding With Stunting And Wasting Of Toddlers In Farmer Families, Betty Yosephin Simanjuntak, Miratul Haya, Desri Suryani, Ali Khomsan, Che An Ahmad

Kesmas

Traditional foods are foods consumed by a certain ethnic group in a specific region. The habit of consuming traditional foods is usually inherited by the family members, including toddlers, of a respective generation. The study aimed to determine relationship of maternal knowledge, attitude, and practices in traditional food feeding with stunting and wasting of toddlers in the farmer families of the Central Bengkulu District. This study employed a cross-sectional design with a sample of mothers with children aged 12–59 months. The sample included a total of 115 farmer families. Data on nutritional knowledge, attitude, practices about traditional food, sex of …


Overweight And Obesity Status With Dental Caries Among Children Aged 7–12 Years Old In Badung District, Bali 2018, Hariani Rafitha, Putri Bungsu Machmud, Ratna Djuwita, Dwi Gayatri, Fakhrana Ariani Ayub Nov 2019

Overweight And Obesity Status With Dental Caries Among Children Aged 7–12 Years Old In Badung District, Bali 2018, Hariani Rafitha, Putri Bungsu Machmud, Ratna Djuwita, Dwi Gayatri, Fakhrana Ariani Ayub

Kesmas

Dental caries is an infectious disease that Dental is characterized by the dental damage resulting from microorganism products in carbohydrate fermentation. Dental caries and obesity in children are multifactorial diseases associated with eating habits and certain lifestyle factors. This study aimed to assess the association between overweightness, obesity, and dental caries among children aged 7–12 years in Badung district, Bali province in 2018. The total sample of 426 children and their mothers were recruited from all first to fifth elementary grade students in three schools selected by simple random sampling. The logistic regression analysis has demonstrated a significant association between …


Personal Exposure Of Traffic Policeman To Particulate Matter In Jakarta: Distribution Of Size, Chemical Composition, And Work Time, Doni Hikmat Ramdhan, Eka Fitriani Ahmad, Fitri Kurniasari, Zuly Prima Rizky, Hardy Atmajaya, Muhayatun Santoso Nov 2019

Personal Exposure Of Traffic Policeman To Particulate Matter In Jakarta: Distribution Of Size, Chemical Composition, And Work Time, Doni Hikmat Ramdhan, Eka Fitriani Ahmad, Fitri Kurniasari, Zuly Prima Rizky, Hardy Atmajaya, Muhayatun Santoso

Kesmas

Particulate matter (PM) is an air pollutant that has an impact on public health, especially in an urban area. The objective of this study was to analyze the personal concentration of PM2.5 and its composition among police working in the roadside area in Jakarta. PM measurement has done to the policeman that controlled traffic on four near highway locations in Jakarta. Sioutas impactor, Leland Legacy personal pump, and quartz fiber filter were chosen to measure the fine particles. Each PM was measured for 8-hour period. PM concentration was analyzed by the gravimetric method while tracing element and black carbon in …


Users’ Perception Of The Hospital Information System In A Maternity Hospital In Lampung, Indonesia, Al Asyary, Arief Kurniawan Nur Prasetyo, Tris Eryando, Solvay Gerke Nov 2019

Users’ Perception Of The Hospital Information System In A Maternity Hospital In Lampung, Indonesia, Al Asyary, Arief Kurniawan Nur Prasetyo, Tris Eryando, Solvay Gerke

Kesmas

Hospital information systems (HIS) have been applied on a massive scale; however, user evaluation of their effectiveness, efficiency, and service quality improvements remain rare. This study aimed to describe the utility of information systems from the users’ point of view by using the Technology Acceptance Model (TAM) in a maternity hospital in Lampung, Indonesia. The study provided an overview of the features of the information system and the workflow of the user through this information system. Screenshots were taken by using Camtasia Studio 2.0 Trial Version application software for one day (two shifts) in the outpatient service. The HIS generally …


Knowledge, Attitude, Practices, And Health Beliefs Of Pregnant Women About Urinary Tract Infection And Its Associated Risk Factors: A Local Filipino Community Experience, Annalyn Navarro, Raphael Enrique Tiongco, Reynaldo Bundalian Jr. Nov 2019

Knowledge, Attitude, Practices, And Health Beliefs Of Pregnant Women About Urinary Tract Infection And Its Associated Risk Factors: A Local Filipino Community Experience, Annalyn Navarro, Raphael Enrique Tiongco, Reynaldo Bundalian Jr.

Kesmas

Urinary tract infection (UTI) during pregnancy is assumed to be associated with increased maternal and fetal morbidity and mortality; hence, a proper assessment of knowledge and practices is crucial to formulate preventive strategies to ensure the health of both the mother and the baby. The study determined the knowledge, attitude, practices (KAP), and the beliefs of pregnant women about UTI based on the Health Belief Model. A survey questionnaire was used to gather data from pregnant women with and without UTI. The association of the pregnant women’s sociodemographic characteristics with their KAP and health beliefs was determined using Pearson’s chi-square …


Midwife’S Role In The Mother-To-Child Transmission Prevention Program In Primary Health Care In Yogyakarta, Niken Meilani, Nanik Setiyawati, Sammy Onyapidi Barasa Nov 2019

Midwife’S Role In The Mother-To-Child Transmission Prevention Program In Primary Health Care In Yogyakarta, Niken Meilani, Nanik Setiyawati, Sammy Onyapidi Barasa

Kesmas

Curing and eradicating Human Immunodeficiency Virus (HIV)/Acquired Immunodeficiency Syndrome (AIDS) are to the core principles of the United Nations’ Sustainable Development Goals (SDGs). The incidence of HIV in the world remains high. Although midwives play a pivotal role in PMTCT implementation, the factors associated with midwives’ role in its implementation are not well understood. The aim of this study was to determine factors associated with midwives’ role in implementation of PMTCT. This study used a cross-sectional design. The subjects were 80 midwives at 14 primary health care in Yogyakarta City, Indonesia. The study was conducted from April to August 2017. …


Sexual Dysfunction Among Women With Diabetes In A Primary Health Care At Semarang, Central Java Province, Indonesia, Lintang Dian Saraswati, Ari Udiyono, Dian Sutrisni, Muh Fauzi Nov 2019

Sexual Dysfunction Among Women With Diabetes In A Primary Health Care At Semarang, Central Java Province, Indonesia, Lintang Dian Saraswati, Ari Udiyono, Dian Sutrisni, Muh Fauzi

Kesmas

Sexual dysfunction is associated with pain during sexual intercourse. Diabetes mellitus (DM) has been reported to be one of the causal factors for sexual dysfunction in women. This cross-sectional study was conducted to describe the status of sexual dysfunction in women with DM in the Tlogosari Kulon Primary Health Care, Semarang, Indonesia, in March 2017. A total of 103 women with DM attending the health center participated in this study. Data were collected using a questionnaire-guided interview and through measurements (blood pressure and random blood glucose test). Results showed that 74.8% of women with DM had sexual dysfunction. The proportion …


Economic Design Of Acceptance Sampling Plans For Truncated Life Tests Using Three-Parameter Lindley Distribution, Amer Ibrahim Al-Omari, Enrico Ciavolino, Amjad D. Al-Nasser Nov 2019

Economic Design Of Acceptance Sampling Plans For Truncated Life Tests Using Three-Parameter Lindley Distribution, Amer Ibrahim Al-Omari, Enrico Ciavolino, Amjad D. Al-Nasser

Journal of Modern Applied Statistical Methods

A single acceptance sampling plan for the three-parameter Lindley distribution under a truncated life test is developed. For various consumer’s confidence levels, acceptance numbers, and values of the ratio of the experimental time to the specified average lifetime, the minimum sample size important to assert a certain average lifetime are calculated. The operating characteristic (OC) function values as well as the associated producer’s risks are also provided. A numerical example is presented to illustrate the suggested acceptance sampling plans.


Post-Acquisition Processing Confounds In Brain Volumetric Quantification Of White Matter Hyperintensities, Ahmed A. Bahrani, Omar M. Al-Janabi, Erin L. Abner, Shoshana H. Bardach, Richard J. Kryscio, Donna M. Wilcock, Charles D. Smith, Gregory A. Jicha Nov 2019

Post-Acquisition Processing Confounds In Brain Volumetric Quantification Of White Matter Hyperintensities, Ahmed A. Bahrani, Omar M. Al-Janabi, Erin L. Abner, Shoshana H. Bardach, Richard J. Kryscio, Donna M. Wilcock, Charles D. Smith, Gregory A. Jicha

Neurology Faculty Publications

BACKGROUND: Disparate research sites using identical or near-identical magnetic resonance imaging (MRI) acquisition techniques often produce results that demonstrate significant variability regarding volumetric quantification of white matter hyperintensities (WMH) in the aging population. The sources of such variability have not previously been fully explored.

NEW METHOD: 3D FLAIR sequences from a group of randomly selected aged subjects were analyzed to identify sources-of-variability in post-acquisition processing that can be problematic when comparing WMH volumetric data across disparate sites. The methods developed focused on standardizing post-acquisition protocol processing methods to develop a protocol with less than 0.5% inter-rater variance.

RESULTS: A series …