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Articles 1 - 3 of 3
Full-Text Articles in Condensed Matter Physics
Frontiers In The Self-Assembly Of Charged Macromolecules, Khatcher O. Margossian
Frontiers In The Self-Assembly Of Charged Macromolecules, Khatcher O. Margossian
Doctoral Dissertations
The self-assembly of charged macromolecules forms the basis of all life on earth. From the synthesis and replication of nucleic acids, to the association of DNA to chromatin, to the targeting of RNA to various cellular compartments, to the astonishingly consistent folding of proteins, all life depends on the physics of the organization and dynamics of charged polymers. In this dissertation, I address several of the newest challenges in the assembly of these types of materials. First, I describe the exciting new physics of the complexation between polyzwitterions and polyelectrolytes. These materials open new questions and possibilities within the context …
An Experimental Study Of Lipid-Membrane Based Structure Formation And Development Of A Responsive System, Rui Cao
Doctoral Dissertations
This thesis shows how controlling adhesive interactions among lipid bilayer vesicles and surrounding polymers or particles leads to formation of new mesoscopic and macroscopic structures. The vesicle-gel reported could find application as a closed-cell, 99% water solid platform for releasing cargo in response to a stimulus, either by tuning membrane permeability or by disruption of the vesicles.
Voltage Driven Translocation Of Polyelectrolytes Through Nanopores, Byoung-Jin Jeon
Voltage Driven Translocation Of Polyelectrolytes Through Nanopores, Byoung-Jin Jeon
Doctoral Dissertations
Recently, translocations of polyelectrolyte molecules through membrane channel protein pores or solid-state nanopores have been actively studied. Although the polymer translocation researches emerged mainly due to technological demands in terms of genome sequencing, the detailed physics of the single molecule transport through a narrow channel remains fully understood. To obtain further understanding of common features of the translocation process, this thesis focuses on the effects of salt concentration, pore-polymer electrostatic interactions, and externally applied electric field on the voltage-driven polymer translocations. The study is carried out by performing a series of systematically designed experiments using alpha-hemolysin (αHL) protein pore to …