Physics Commons^™

Quantitative Analysis Of Human Blood Serum Using Vibrational Spectroscopy., Hugh Byrne, Franck Bonnier, Jennifer Mcintyre, Drishya Rajan Parachalil

Articles

Analysis of bodily fluids using vibrational spectroscopy has attracted increasing attention in recent years. In particular, infrared spectroscopic screening of blood products, particularly blood serum, for disease diagnostics has been advanced considerably, attracting commercial interests. However, analyses requiring quantification of endogenous constituents or exogenous agents in blood are less well advanced. Recent advances towards this end are reviewed, focussing on infrared and Raman spectroscopic analyses of human blood serum. The importance of spectroscopic analysis in the native aqueous environment is highlighted, and the relative merits of infrared absorption versus Raman spectroscopy are considered, in this context. It is argued that …

Investigation Of The Chemical Composition Of Plasma-Treated Water By Midiplexc And Its Antimicrobial Effect On L. Monocytogenes And Pseudomonas Fluorescens Monospecies Suspension Cultures, Oliver Handorf, Harald Below, Uta Schnabel, Katharina Riedel

Articles

Plasma -generated compounds conceived by microwave -induced plasma (MidiPLexc) were physicochemically investigated in their molecular compositions. Therefore, plasma -treated water (PTW) was generated by treatment with the MidiPLexc within a 1 l glass bottle for a pre -treatment time of 100 s, 300 s and 900 s. The PTW was further investigated in its composition of reactive oxygen/nitrogen species. For this purpose, the hydrogen peroxide (H2O2) concentration of the PTW was determined electrochemically using chronoamperometry, and the anionic components were determined using ion chromatography. As a result, H2O2 concentrations of up to 720 mg l−1 , nitrite concentrations of 1600 …

Empirical Study On The Effects Of Acquisition Parameters For Ftir Hyperspectral Imaging Of Brain Tissue, David Perezguaita, Julia Sacharz, Mustafa Kasniz, Shaiju Nazeer, Bayden Wood, Philip Heraud

Articles

Fourier transform infrared (FTIR) spectroscopic imaging is a powerful technique for molecular imaging of pathologies associated with the nervous systems including multiple sclerosis research. However, there is no standard methodology or standardized protocol for FTIR imaging of tissue sections that maximize the ability to discriminate between the molecular, white and granular layers, which is essential in the investigation of the mechanism of demyelination process. Tissue sections are heterogeneous, complex and delicate, hence the parameters to generate high quality images in minimal time becomes essential in the modern clinical laboratory. This article presents an FTIR spectroscopic imaging study of post-mortem human …

Microfluidic Flow Direction And Rate Vector Sensor Based On A Partially Gold-Coated Tfbg, Changyu Shen, Dejun Liu, Xiaokang Lian, Tingting Lang, Chunliu Zhao, Yuliya Semenova, Jacques Albert

Articles

In microfluidic chips applications, the monitoring of the rate and the direction of a microfluidic flow is very important. Here, we demonstrate a liquid flow rate and a direction sensor using a partially gold-coated tilted fiber Bragg grating (TFBG) as the sensing element. Wavelength shifts and amplitude changes of the TFBG transmission resonances in the near infrared reveal the direction of the liquid flowing along the fiber axis in the vicinity of the TFBG due to a nanoscale gold layer over part of the TFBG. For a device length of 10 mm (and a diameter of 125 µm for easy …

Simultaneous Measurement Of Displacement And Temperature Based On Two Cascaded Balloon-Like Bent Fibre Structures, Ke Tian, Ruoning Wang, Meng Zhang, Xiafan Wang, Xin Wang, Guoyong Jin, Elfed Lewis, Gerald Farrell, Pengfei Wang

Articles

A low-cost optical fibre sensor based on two cascaded balloon-like bent fibre (BBF) structures for simultaneous displacement and temperature measurement is reported. The sensor is fabricated by cascading two balloon-like bent single-mode fibres (SMFs) which with different bending radii, generating two separate interference dips within a limited wavelength range. The wavelength of the two interference dips exhibits different responses to external displacement and temperature variations, hence simultaneous measurement of displacement and temperature is realized. Experimental results show that the proposed optical fibre sensor achieves a displacement sensitivity of −318.8 pm/μm and a temperature sensitivity of 47.4 pm/°C. Taking advantage of …

Nis2 As A Broadband Saturable Absorber For Ultrafast Pulse Lasers, Pengfei Wang, Han Zhang, Yu Yin, Qiuyun Ouyang, Yujin Chen, Elfed Lewis, Gerald Farrell, Masaki Tokurakawa, Sulaiman Wadi Harun, Cong Wang, Shi Li

Articles

Nickel disulfide (NiS2) has recently been found to possess strong nonlinear saturable absorption properties. This feature is highly attractive for nonlinear photonics applications. Ultrafast pulse generation is successfully demonstrated in this article for both Ytterbium- and Erbium-doped fibre lasers using micro-fibre deposited nickel disulfide (NiS2) as a saturable absorber (SA). The fabricated SA device has a modulation depth of 23% at 1.06 μm and 30.8% at 1.55 μm. Stable dissipative soliton operation was achieved at 1064.5 nm with a pulse duration of 11.7 ps and another stable conventional soliton pulse train was also obtained at 1560.2 nm with a pulse …

Intense Mid-Infrared Emission At 3.9 Μm In Ho3+-Doped Zbya Glasses For Potential Use As A Fiber Laser, Haiyan Zhao, Ruicong Wang, Xin Wang, Shijie Jia, Yaxian Fan, Elfed Lewis, Gerald Farrell, Shunbin Wang, Pengfei Wang

Articles

Intense mid-infrared emission at 3.9 µm in Ho3+-doped ZBYA glasses with direct upper laser level (Ho3+ : 5 I5) pumping at a wavelength of 888 nm is reported for the first time, to the best of our knowledge. Spectroscopic parameters were determined using the Judd–Ofelt theory and the measured absorption spectrum. The maximum emission cross section of the Ho3+-doped ZBYA glass is estimated to be 2.7 × 10−21 cm2 at 3906 nm. Additionally, fluorescence spectra and lifetimes of ZBYA glasses with different Ho3+ ion doping concentrations were measured. The results provide theoretical and experimental basis for better selection of rare-earth-doped …

On The Intermediate Long Wave Propagation For Internal Waves In The Presence Of Currents, Joseph Cullen, Rossen Ivanov

Articles

A model for the wave motion of an internal wave in the presence of current in the case of intermediate long wave approximation is studied. The lower layer is considerably deeper, with a higher density than the upper layer. The flat surface approximation is assumed. The fluids are incompressible and inviscid. The model equations are obtained from the Hamiltonian formulation of the dynamics in the presence of a depth-varying current. It is shown that an appropriate scaling leads to the integrable Intermediate Long Wave Equation (ILWE). Two limits of the ILWE leading to the integrable Benjamin-Ono and KdV equations are …

Stacked Volume Holographic Gratings For Extending The Operational Wavelength Range In Led And Solar Applications, Sanjay Keshri, Julia Marín-Sáez, Izabela Naydenova, Kevin Murphy, Jesús Atencia, Daniel Chemisana, Sean Garner, María-Victoria Collados, Suzanne Martin

Articles

A novel stacking procedure is presented for volume phase holographic gratings (VPHGs) recorded in photopolymer material using Corning Willow Glass as a flexible substrate in order to achieve broader angular and spectral selectivity in a diffractive device with high efficiency for solar and LED applications. For the first time to our knowledge, we have shown a device designed for use with a white LED that has the same input and output angles and high efficiency when illuminated by different wavelengths. In this paper, two VPHGs were designed, experimentally recorded, and tested when illuminated at normal incidence. The experimental approach is …

An Investigation Of The Detection Capability Of Pulsed Wave Duplex Doppler Of Low Grade Stenosis Using Ultrasound Contrast Agent Microbubbles – An In-Vitro Study, Jacinta Browne, Deirdre King, Andrew Fagan, Deepa Chari, Carmel Moran

Articles

Objective: The objective of the study was to investigate whether clinically used ultrasonic contrast agents improved the accuracy of spectral Doppler ultrasound in the detection of low grade (< 50%) renal artery stenosis. Low grade stenoses in the renal artery are notoriously difficult to reliably detect using Doppler ultrasound due to difficulties such as overlying fat and bowel gas.

Methods: A range of anatomically-realistic renal artery phantoms with varying low degrees of stenosis (0, 30 and 50%) were constructed and peak velocity data was measured from within the pre-stenotic and mid-stenotic regions in each phantom, for both unenhanced and contrast-enhanced spectral Doppler data acquisitions. The effect of a 20mm overlying fat layer on the ultrasound beam distortion and phase aberration, and hence on the measured peak velocity data, was also …

Use Of Novel Anthropomorphic Breast Ultrasound Phantoms For Radiology Resident Education, Jacinta Browne, Chris Gu, Robert Fazzio, Andrew Fagan, Donald Tradup, Nicholas Hangiandreou

Articles

Purpose: This study evaluated the training and assessment role of anthropomorphic breast ultrasound phantoms which simulated both the morphological and sonographic characteristics of breast tissue, including lesions, in a group of radiology residents at a large academic medical center. Methods: This was a prospective study involving 9 residents across all years (2^nd–4^th year) of a radiology residency program. Baseline assessments of all residents ability to detect and characterize lesions in P-I were carried out, followed by a two-hour teaching session on the same phantom. All residents underwent a post-training, final assessment on P-II to evaluate changes in …

Distribution Of Tm 3+ And Ni 2+ In Chalcogenide Glass Ceramics Containing Ga2s3 Nanocrystals: Influence On Photoluminescence Properties, Xiaosong Lu, Zhiqiang Lai, Jing Ren, Lukas Strizik, Tomas Wagner, Yanqiu Du, Gerald Farrell, Pengfei Wang

Articles

The distribution of Tm3+ and Ni2+ ions is unambiguously exhibited in 80GeS2-20Ga2S3 chalcogenide glass ceramics (GCs) containing Ga2S3 nanocrystals (NCs) by using advanced analytical transmission electron microscopy. Distinctively different distribution patterns of Tm3+ and Ni2+ ions are observed in the GCs obtained by controlled crystallization. The distribution of the dopants imposes strong influence on their optical properties which are revealed by absorption and photoluminescence (PL) spectra. Detailed discussions are given of the mechanisms of the crystallization-induced PL enhancement and quenching of the Tm3+ mid-infrared and Ni2+ near-infrared emissions, respectively.

Investigation Of The Assessment Of Low Degree (<50%) Renal Artery Stenosis Based On Velocity Flow Profile Analysis Using Doppler Ultrasound: An In-Vitro Study, Andrew Malone, Deepa Chari, Sean Cournane, Izabela Naydenova, Andrew Fagan, Jacinta Browne

Articles

Purpose: Renal arterial stenosis can lead to disrupted renal function due to reduced blood flow to the kidneys and is largely thought to be caused by atherosclerosis. Current diagnostic strategies for renal arterial stenosis rely on detecting large degree stenoses (>50%). This study aimed to test the viability of using Doppler ultrasound to assess velocity profiles to detect the presence of low degree (<50%) stenoses.

Methods: A series of anatomically realistic renal artery flow phantoms were constructed exhibiting a range of low degree stenoses (symmetric and asymmetric). The behaviour of fluid flow in the phantoms was examined using Doppler ultrasound …

Concentric Double Hollow Grid Cathode Discharges, C. T. Teodorescu-Soare, S. A. Irimiciuc, C. Ionita, D. G. Dimitriu, B. Hodoroaba, T. O'Hara, O. Vasilovici, L. Amarandi, R. W. Schrittwieser

Articles

A new cathode system, consisting of two concentric spherical hollow grids with two aligned orifices, is investigated by space-resolved Langmuir probe measurements and non-linear dynamics analysis. Negative biases of this spherical hollow grids arrangement lead to the formation of two complex space charge structures in the regions of the orifices. The overall dynamics of the current-voltage characteristic (I–V characteristic) of each discharge is characterized by strong oscillatory behaviour with various waveforms correlated with jumps in the static I–V characteristics. Space-resolved measurements through the two aligned orifices of the two grids show a peak increase of the electron temperature and particle …

Sns Optical Fiber Structure Sensor For Direct Detection Of The Phase Transition In C18h38 N-Alkane Material, Wei Han, Marek Rebow, Xiaokang Lian, Dejun Liu, Gerald Farrell, Qiang Wu, Yuliya Semenova

Articles

A singlemode-no-core-singlemode (SNS) fiber structure optical sensor for detecting the solid-liquid phase change in a phase change material: C18H38 n-alkane material (n-octadecane) is proposed and demonstrated. The transmission-type sensor probe consists of a short section of no-core fiber sandwiched between two sections of a singlemode fiber. Phase changes in n-octadecane are accompanied by large step-like variations of its refractive index (RI). Such a large discontinuous change of the n-octadecane’s RI during its phase transition, leads to the corresponding step-like change in the transmitted optical power that can reliably indicate the phase change of the sample in the vicinity of the …

Impact Of Plasma Treatment On Acoustic Properties Of Natural Cellulose Materials, Sanja S. Pavlović, Snežana B. Stanković, Andrijana Žekić, Miloš Nenadović, Dušan M. Popović, Vladimir Milosavljevic, Goran B. Poparić

Articles

Low-temperature plasma is widely used in many surface treatment technologies for modifications of the physical properties of different polymeric materials. In the present work, we have examined the modification of acoustical properties of natural cellulose materials (cotton, hemp) by the radio-frequency argon plasma. We have observed an increase of the sound absorption coefficient due to the plasma treatment for certain range of applied powers. An analysis of elementary processes which happened during plasma–material interaction was conducted. Additional analyses related to material characterizations were performed in order to resolve structural and chemical changes of plasma treated materials. The micro-mechanical modification of …

Exploring Subcellular Responses Of Prostate Cancer Cells To X-Ray Exposure By Raman Mapping, Maciej Roman, Agnieszka Panek, Hugh Byrne, Tomasz P Wrobel, Esen Efeoglu, Czeslawa Paluszkiewicz, Wojciech Maria Kwiatek

Articles

Understanding the response of cancer cells to ionising radiation is a crucial step in modern radiotherapy. Raman microspectroscopy, together with Partial Least Squares Regression (PLSR) analysis has been shown to be a powerful tool for monitoring biochemical changes of irradiated cells on the subcellular level. However, to date, the majority of Raman studies have been performed using a single spectrum per cell, giving a limited view of the total biochemical response of the cell. In the current study, Raman mapping of the whole cell area was undertaken to ensure a more comprehensive understanding of the changes induced by X-ray radiation. …

Magnetic Field Sensor Based On A Tri-Microfiber Coupler Ring In Magnetic Fluid And A Fiber Bragg Grating, Fangfang Wei, Dejun Liu, Arun Kumar Mallik, Gerald Farrell, Qiang Wu, Gang-Ding Peng, Yuliya Semenova

Articles

In this paper we propose and investigate a novel magnetic field sensor based on a Tri-microfiber coupler combined with magnetic fluid and a fiber Bragg grating (FBG) in a ring. A sensitivity of 1306 pm/mT was experimentally demonstrated in the range of magnetic fields from 0 to 15 mT. The reflection peak in the output spectrum associated with the FBG serves as a reference point allowing to avoid ambiguity in determining the spectral shift induced by the magnetic field. Due to its high sensitivity at low magnetic fields, the proposed structure could be of high interest in low field biosensing …

Surface Waves Over Currents And Uneven Bottom, Alan Compelli, Rossen Ivanov, Calin I. Martin, Michail D. Todorov

Articles

The propagation of surface water waves interacting with a current and an uneven bottom is studied. Such a situation is typical for ocean waves where the winds generate currents in the top layer of the ocean. The role of the bottom topography is taken into account since it also influences the local wave and current patterns. Specific scaling of the variables is selected which leads to approximations of Boussinesq and KdV types. The arising KdV equation with variable coefficients, dependent on the bottom topography, is studied numerically when the initial condition is in the form of the one soliton solution …

Equatorial Wave–Current Interactions, Adrian Constantin, Rossen Ivanov

Articles

We study the nonlinear equations of motion for equatorial wave–current interactions in the physically realistic setting of azimuthal two-dimensional inviscid flows with piecewise constant vorticity in a two-layer fluid with a flat bed and a free surface. We derive a Hamiltonian formulation for the nonlinear governing equations that is adequate for structure-preserving perturbations, at the linear and at the nonlinear level. Linear theory reveals some important features of the dynamics, highlighting differences between the short- and long-wave regimes. The fact that ocean energy is concentrated in the long-wave propagation modes motivates the pursuit of in-depth nonlinear analysis in the long-wave …

Relationship Of Ndvi And Oak (Quercus)Pollen Including A Predictive Model In The Sw Mediterranean Region, Rocío González-Naharro, Elia Quirós, Santiago Fernández-Rodríguez, Inmaculada Silva-Palacios, J. M. Maya-Manzano, Rafael Tormo-Molina, Raúl Pecero-Casimiro, Alejandro Monroy-Colin, Ángela Gonzalo-Garijo

Articles

Techniques of remote sensing are being used to develop phenological studies. Our goal is to study the correlation among the Normalized Difference Vegetation Index (NDVI) related with oak trees included in three set data polygons (15, 25 and 50 km to aerobiological sampling point as NDVI-15, 25 and 50), and oak (Quercus) daily average pollen counts from 1994 to 2013. The study was developed in the SW Mediterranean region with continuous pollen recording within the mean pollen season of each studied year. These pollen concentrations were compared with NDVI values in the locations containing the vegetation under a study based …

Third-Order Optical Nonlinearity Properties Of Cdcl2-Modifed Ge–Sb–S Chalcogenide Glasses, Xiaosong Lu, Jianhui Li, Lu Yang, Runan Zhang, Yindong Zhang, Jing Ren, Aurelian Catalin Galca, Mihail Secu, Gerald Farrell, Pengfei Wang

Articles

We developed a new type of chalcohalide glasses with physicochemical and nonlinear optical properties that are tunable by composition. It is found that more than 60 mol.% CdCl2 heavy metal halide can be dissolved into the ternary Ge–Sb–S system and forming stable glasses. The visible-light transparency range is extended to shorter wavelengths with the addition of CdCl2, which is beneficial for the optical quality control and infra-red (IR) system alignment. The third-order optical nonlinearity (TONL) is studied using the femtosecond Z-scan method. The results show that both the nonlinear refractive index and two photon absorption co-efficient decrease with CdCl2. Benefiting …

All Fibre Q-Switched Thulium-Doped Fibre Laser Incorporating Thulium–Holmium Co-Doped Fibre As A Saturable Absorber, Shi Li, Elfed Lewis, Gerald Farrell, Ahmad Haziq Aiman Rosol, A.A. Latiff, Sulaiman Wadi Harun, Bingang Guo, Pengfei Wang

Articles

A novel all fibre Q-switched Thulium-doped fibre laser (TDFL) is reported which includes a short length of a Thulium–Holmiumco-doped fibre (THDF) as a saturable absorber. A high repetition rate (27.26 kHz) coupled with a low pulse width (19.06μs) is obtained for single wavelength Q-switched pulse operation at an output wavelength of 1911.5 nm using a pump power of 200 mW. Increasing the pump power from 200 mW to 700 mW results in the repetition rate increasing from 27.26 kHz to 99.67 kHz and the pulse width decreasing from 19.06μs to 920 ns. The centre wavelength of the single Q-switched pulse …

A Twelve-Wavelength Thulium-Doped Fibre Laser Based On A Microfibre Coil Resonator Incorporating Black Phosphorus, Shi Li, Yu Yin, Elfed Lewis, Gerald Farrell, Pengfei Wang

Articles

A novel multi-wavelength continuous Thulium-doped fibre laser incorporating a microfibre coil resonator based on black phosphorus (MCR-BP) material has been successfully fabricated and demonstrated. A twelve-wavelength spectrum with 0.54 nm channel spacing has been achieved by simply adjusting the pump source power. A single peak extinction ratio of more than 40 dB was observed. The superior performance of the MCR-BP described in this article compared to conventional MCR based fibre lasers can be attributed the inclusion of the Black Phosphorous Material. The enhanced lasing is primarily due to the twin properties of the MCR-BP device combining a comb-like filter effect …

Ultrabroadband Mid-Infrared Emission From Cr 2+ -Doped Infrared Transparent Chalcogenide Glass Ceramics Embedded With Thermally Grown Zns Nanorods, Xiaosong Lu, Zhiqiang Lai, Runan Zhang, Haitao Guo, Jing Ren, Lukas Strizik, Tomas Wagner, Gerald Farrell, Pengfei Wang

Articles

We report, for the first time to our knowledge, an ultrabroadband mid-infrared (MIR) emission in the range of 1800–2800 nm at room temperature from a Cr2+-doped chalcogenide glass ceramic embedded with pure hexagonal (wurtzite) β-ZnS nanorods and study the emission-dependent properties on the doping concentration of Cr2+. A new family of chalcogenide glasses based on (100 − x) Ge1.5As2S6.5 – x ZnSe (in mol.%) was prepared by melt-quenching method. The Cr2+: β-ZnS nanorods of ˜150 nm in diameter and ˜1 μm in length were grown in the Cr2+-doped glass after thermal annealing. The compositional variations of glass structures and optical …

In-Fiber Temperature Sensor Based On Green Up-Conversion Luminescence In An Er3+-Yb3+ Co-Doped Tellurite Glass Microsphere, Meng Zhang, Angzhen Li, Jibo Yu, Xiaosong Lu, Shunbin Wang, Elfed Lewis, Gerald Farrell, Libo Yuan, Pengfei Wang

Articles

A novel, to the best of our knowledge, in-fiber temperature sensor based on green up-conversion (UC) luminescence in an Er3+-Yb3+" role="presentation" style="box-sizing: border-box; display: inline; font-size: 12.88px; line-height: normal; word-spacing: normal; overflow-wrap: normal; white-space: nowrap; float: none; direction: ltr; max-width: none; max-height: none; min-width: 0px; min-height: 0px; border: 0px; padding: 0px; margin: 0px; position: relative;">Er3+-Yb3+Er3+-Yb3+ co-doped tellurite glass microsphere is described. The tellurite glass microsphere is located firmly inside a suspended tri-core hollow-fiber (STCHF) structure. The pump light launched via a single-mode fiber (SMF) is passed through a section of multimode fiber, which is fusion spliced between the SMF …

Vacuum Polarization For Varying Quantum Scalar Field Parameters In Schwarzschild–Anti–De Sitter Spacetime, Cormac Breen, Peter Taylor

Articles

Equipped with new powerful and efficient methods for computing quantum expectation values in static-spherically symmetric spacetimes in arbitrary dimensions, we perform an in-depth investigation of how the quantum vacuum polarization varies with the parameters in the theory. In particular, we compute and compare the vacuum polarization for a quantum scalar field in the Schwarzschild–anti–de Sitter black hole spacetime for a range of values of the field mass and field coupling constant as well as the black hole mass and number of spacetime dimensions. In addition, a new approximation for the vacuum polarization in asymptotically anti–de Sitter black hole spacetimes is …

Raman Spectroscopy Detects Biochemical Changes Due To Different Cell Culture Environments In Live Cells In Vitro, Mahmoud Gargotti, Esen Efeoglu, Hugh Byrne, Alan Casey

Articles

The in vitro cell culture environment can impact on cell biochemistry and cell cycle. The manifestation of such substrate-induced changes in cell cycle in the Raman microspectroscopic profiles of cell cultures is investigated at the level of nucleolus, nucleus and cytoplasm. HeLa immortalised human cervical cells and HaCaT dermal cells were cultured on three different substrates, conventional polystyrene cell culture dishes, CaF2 slides as a commonly used Raman substrate, and glass slides coated with Collagen Rat Tail, as a mimic of the extra cellular matrix (ECM) environment. A cell cycle study, based on percentage DNA content, as determined using Propidium …

Significance Of A Non-Thermal Plasma Treatment On Ldpe Biodegradation With Pseudomonas Aeruginosa, Laurence Scally, Miroslav Gulan, Lars Weigang, Patrick Cullen, Vladimir Milosavljevic

Articles

The use of plastics has spanned across almost all aspects of day to day life. Although their uses are invaluable, they contribute to the generation of a lot of waste products that end up in the environment and end up polluting natural habitats such as forests and the ocean. By treating low-density polyethylene (LDPE) samples with non-thermal plasma in ambient air and with an addition of 4% CO2, the biodegradation of the samples can be increased due to an increase in oxidative species causing better cell adhesion and acceptance on the polymer sample surface. It was, however, found that the …

Serialised Holography For Brand Protection And Authentication, Dinesh Vather, Izabela Naydenova, Dervil Cody, Monika Zawadzka, Suzanne Martin, Emilia Mihaylova, Stephen Curran, Paul Duffy, Josune Portillo, Daniel Connell, Stephen Mcdonnell, Vincent Toal

Articles

The problems presented by counterfeit products and documentation are discussed. Limitations of existing holograms for anti-counterfeit applications are described. We describe the advantages of full holographic serialisation and the requirements in terms of materials and techniques for mass production of true serialised holograms. These requirements having been met, we report for the first time the mass production of fully serialised holograms. The novelty of approach consists of the direct use of product manufacturer’s information as the object in a holographic recording system along with a self-processing photopolymer and modular optical system to facilitate mass production of truly serialised volume holograms. …