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Articles 31 - 60 of 590
Full-Text Articles in Physics
3F4 Hypergeometric Functions As A Sum Of A Product Of 2F3 Functions, Jack C. Straton
3F4 Hypergeometric Functions As A Sum Of A Product Of 2F3 Functions, Jack C. Straton
Physics Faculty Publications and Presentations
This paper shows that certain 3F4 hypergeometric functions can be expanded in sums of pair products of 2F3 functions, which reduce in special cases to 2F3 functions expanded in sums of pair products of 1F2 functions. This expands the class of hypergeometric functions having summation theorems beyond those expressible as pair-products of generalized Whittaker functions, 2F1 functions, and 3F2 functions into the realm of pFq functions where p < q for both the summand and terms in the series. In addition to its intrinsic value, this result has a specific application in calculating the response of the atoms to laser stimulation in the Strong Field Approximation.
The Fourier–Legendre Series Of Bessel Functions Of The First Kind And The Summed Series Involving 1F2 Hypergeometric Functions That Arise From Them, Jack C. Straton
The Fourier–Legendre Series Of Bessel Functions Of The First Kind And The Summed Series Involving 1F2 Hypergeometric Functions That Arise From Them, Jack C. Straton
Physics Faculty Publications and Presentations
The Bessel function of the first kind JN(kx) is expanded in a Fourier–Legendre series, as is the modified Bessel function of the first kind IN(kx). The purpose of these expansions in Legendre polynomials was not an attempt to rival established numerical methods for calculating Bessel functions but to provide a form for JN(kx) useful for analytical work in the area of strong laser fields, where analytical integration over scattering angles is essential. Despite their primary purpose, one can easily truncate the series at 21 terms to provide 33-digit accuracy that matches the IEEE extended precision in …
Integral Representations Over Finite Limits For Quantum Amplitudes, Jack C. Straton
Integral Representations Over Finite Limits For Quantum Amplitudes, Jack C. Straton
Physics Faculty Publications and Presentations
We extend previous research to derive three additional M-1-dimensional integral representations over the interval [0,1]" The prior version covered the interval [0,∞]" role="presentation position: relative;">[0,∞][0,∞]. This extension applies to products of M Slater orbitals, since they (and wave functions derived from them) appear in quantum transition amplitudes. It enables the magnitudes of coordinate vector differences (square roots of polynomials) |x1−x2|=x12−2x1x2cosθ+x22" to be shifted from disjoint products of functions into a single quadratic form, allowing for the completion of its square. The M-1-dimensional integral representations of M Slater orbitals that both this extension and the prior version introduce …
Electromagnetic Fields And Radiation From Localized Current Source Interacting With A Cosmic Axion Field In The Context Of Massive Axion Electrodynamics, Railing Chang, P. T. Leung
Electromagnetic Fields And Radiation From Localized Current Source Interacting With A Cosmic Axion Field In The Context Of Massive Axion Electrodynamics, Railing Chang, P. T. Leung
Physics Faculty Publications and Presentations
Electromagnetic fields from localized current source interacting with an oscillatory cosmic axion field are studied, accounting for the possibility of a finite photon mass. In particular, focus will be on the dipole radiation from static current sources. The Proca theory is generalized to include the axion field and solutions to the modified EM field equations are obtained to first order in the axion coupling parameter. Analysis of the interplay between the two vanishingly small parameters – the axion mass (via the coupling constant and the oscillating frequency) and the photon mass – is carried out with reference to possible future …
The Use Of Fluorescence Lifetime Imaging (Flim) For In Situ Microbial Detection In Complex Mineral Substrates, Yekaterina G. Chmykh, Jay Nadeau
The Use Of Fluorescence Lifetime Imaging (Flim) For In Situ Microbial Detection In Complex Mineral Substrates, Yekaterina G. Chmykh, Jay Nadeau
Physics Faculty Publications and Presentations
The utility of fluorescence lifetime imaging microscopy (FLIM) for identifying bacteria in complex mineral matrices was investigated. Baseline signals from unlabelled Bacillus subtilis and Euglena gracilis, and Bacillus subtilis labelled with SYTO 9 were obtained using two-photon excitation at 730, 750 and 800 nm, identifying characteristic lifetimes of photosynthetic pigments, unpigmented cellular autofluorescence, and SYTO 9. Labelled and unlabelled B. subtilis were seeded onto marble and gypsum samples containing endolithic photosynthetic cyanobacteria and the ability to distinguish cells from mineral autofluorescence and nonspecific dye staining was examined in parallel with ordinary multichannel confocal imaging. It was found that FLIM …
Multi-Agent Deep Reinforcement Learning For Radiation Localization, Benjamin Scott Totten
Multi-Agent Deep Reinforcement Learning For Radiation Localization, Benjamin Scott Totten
Dissertations and Theses
For the safety of both equipment and human life, it is important to identify the location of orphaned radioactive material as quickly and accurately as possible. There are many factors that make radiation localization a challenging task, such as low gamma radiation signal strength and the need to search in unknown environments without prior information. The inverse-square relationship between the intensity of radiation and the source location, the probabilistic nature of nuclear decay and gamma ray detection, and the pervasive presence of naturally occurring environmental radiation complicates localization tasks. The presence of obstructions in complex environments can further attenuate the …
Uhv-Shear-Force Acoustic Near-Field Microscopy And Its Implementation In The Study Of Confined Mesoscopic Fluids, Theodore Alex Brockman
Uhv-Shear-Force Acoustic Near-Field Microscopy And Its Implementation In The Study Of Confined Mesoscopic Fluids, Theodore Alex Brockman
Dissertations and Theses
The design, construction, and implementation of Shear-force Acoustic Near-Field Microscopy (SANM), operational from ultrahigh vacuum (UHV) to ambient conditions--offering a pristine environment for more reliable characterization the hydrophobic/hydrophilic wetting properties of surfaces--is presented. SANM capitalizes on its sensitivity to the evanescent near-field acoustic emissions from a mesoscopic fluid (confined between the apex of a laterally oscillating tapered nanosized probe and a flat substrate) when subjected to shear motion. This distinct capability provides direct access to the fluid’s viscoelastic response when subjected to shear interactions, in contrast to indirect measurements performed by other standard probe proximity scanning techniques. The entire …
Stability Of Retinol In Liposomes As Measured By Fluorescence Lifetime Spectroscopy And Flim, Louis Sumrall, L. Smith, Elmukhtar Ehmed Alhatmi, Yekaterina G. Chmykh, D. Mitchell, Jay Nadeau
Stability Of Retinol In Liposomes As Measured By Fluorescence Lifetime Spectroscopy And Flim, Louis Sumrall, L. Smith, Elmukhtar Ehmed Alhatmi, Yekaterina G. Chmykh, D. Mitchell, Jay Nadeau
Physics Faculty Publications and Presentations
Retinol shows complex photophysical properties that make it potentially useful as an exogenous or endogenous probe of membrane microenvironment, but it has not been fully explored. In this study, we use bulk fluorescence lifetime measurements and fluorescence lifetime imaging microscopy (FLIM) to examine the stability of retinol in phosphatidylcholine (PC) multilamellar and unilamellar vesicles with and without cholesterol. We find that both light and exposure to ambient temperature and oxygen contribute to retinol degradation, with the addition of an antioxidant such as butylated hydroxytoluene (BHT) essential to provide stability, especially in the absence of cholesterol. With exposure to ultraviolet light …
Flash-Rt: Using High-Dose Radiation For Clinical Radiation Therapy, Deja Stubbs
Flash-Rt: Using High-Dose Radiation For Clinical Radiation Therapy, Deja Stubbs
University Honors Theses
This paper is a literature review on the possible mechanisms behind the FLASH effect and why such research can advance the world of radiology treatment by modifying current clinical linear accelerators to produce ultra-high doses of radiation. Radiation Therapy, also known as external Beam Radiation Therapy, is a common type of cancer treatment. Globally, cancer is the second-leading cause of death, but has seen an increase in survival rates over the past couple of years. Cancer can develop in almost any part of the body since cancer is defined as uncontrolled cell growth. The FLASH Effect is seen when treating …
A Simple In Situ Method For Optimizing Settings For The Einzel Lens Elements In A Focused Ion Beam, Rich Swinford, Erik Sanchez
A Simple In Situ Method For Optimizing Settings For The Einzel Lens Elements In A Focused Ion Beam, Rich Swinford, Erik Sanchez
Physics Faculty Publications and Presentations
Ion beams have had an incredible impact on research in the past couple of decades. One major reason for this is the continued development of systems having optimal beam currents that allows one to image more clearly at different spot sizes to include higher currents that allow for faster milling. The advancements for Focused ion beam (FIB) columns have developed rapidly due to the computational optimization of lens designs. However, once a system has been produced, the optimal column settings for these lenses may change or simply become obscure. Our work involves regaining this optimization with the newly applied values …
Microbial Motility At The Bottom Of North America: Digital Holographic Microscopy And Genomic Motility Signatures In Badwater Spring, Death Valley National Park, Carl Snyder, Jakob P. Centlvre, Shrikant Bhute, Jay Nadeau, Multiple Additional Authors
Microbial Motility At The Bottom Of North America: Digital Holographic Microscopy And Genomic Motility Signatures In Badwater Spring, Death Valley National Park, Carl Snyder, Jakob P. Centlvre, Shrikant Bhute, Jay Nadeau, Multiple Additional Authors
Physics Faculty Publications and Presentations
Motility is widely distributed across the tree of life and can be recognized by microscopy regardless of phylogenetic affiliation, biochemical composition, or mechanism. Microscopy has thus been proposed as a potential tool for detection of biosignatures for extraterrestrial life; however, traditional light microscopy is poorly suited for this purpose, as it requires sample preparation, involves fragile moving parts, and has a limited volume of view. In this study, we deployed a field-portable digital holographic microscope (DHM) to explore microbial motility in Badwater Spring, a saline spring in Death Valley National Park, and complemented DHM imaging with 16S rRNA gene amplicon …
Thin Film Deposition Of Mop, A Topological Semimetal, Robert Browning, Paul Plachinda, Raj Solanki
Thin Film Deposition Of Mop, A Topological Semimetal, Robert Browning, Paul Plachinda, Raj Solanki
Physics Faculty Publications and Presentations
MoP is a topological semimetal which has drawn attention due to its unique electrical and optical properties resulting from massless electrons. In order to utilize these properties for practical applications, it is necessary to develop a technique to produce high-quality, large-scale thin films of this 2D material. We report below our initial results of growth of MoP thin films using atomic layer deposition (ALD), where the film grows layer-by-layer. These films were grown on 5 cm × 5 cm silicon oxide coated Si wafers. Resistivity versus temperature measurements show that these films are metallic and includes a partial superconducting phase. …
Recent Advances In Experimental Design And Data Analysis To Characterize Prokaryotic Motility, Megan M. Dubay, Jacqueline Acres, Max Riekeles, Jay Nadeau
Recent Advances In Experimental Design And Data Analysis To Characterize Prokaryotic Motility, Megan M. Dubay, Jacqueline Acres, Max Riekeles, Jay Nadeau
Physics Faculty Publications and Presentations
Bacterial motility plays a key role in important cell processes such as chemotaxis and biofilm formation, but is challenging to quantify due to the small size of the individual microorganisms and the complex interplay of biological and physical factors that influence motility phenotypes. Swimming, the first type of motility described in bacteria, still remains largely unquantified. Light microscopy has enabled qualitative characterization of swimming patterns seen in different strains, such as run and tumble, run-reverse-flick, run and slow, stop and coil, and push and pull, which has allowed for elucidation of the underlying physics. However, quantifying these behaviors (e.g., identifying …
Electromagnetic Radiation From A Spherical Static Current Source Coupled To Harmonic Axion Field, Railing Chang, Huai-Yi Xie, P. T. Leung
Electromagnetic Radiation From A Spherical Static Current Source Coupled To Harmonic Axion Field, Railing Chang, Huai-Yi Xie, P. T. Leung
Physics Faculty Publications and Presentations
The electromagnetic fields generated from a static current source on a spherical surface are calculated in the framework of axion electrodynamics to first order in the coupling parameter. Comparisons of the results are made with reference to various results obtained in conventional Maxwell electrodynamics, as well as previous results obtained for point magnetic dipole source coupled to harmonic axion fields. Distinct features from the results so obtained are highlighted for possible experimental probing of the axions via electromagnetic interactions. In particular, electromagnetic radiation from sources with strong magnetic field is studied which may enable the detection of a cosmic …
Possibilities For Inertial Electrostatic Confinement Fusion, Jeffrey Edward Black
Possibilities For Inertial Electrostatic Confinement Fusion, Jeffrey Edward Black
Dissertations and Theses
While most of the fusion energy research is focused on magnetic confinement, there have been several alternative confinement methods aimed at the development of smaller and less expensive reactors. A number of these devices utilize a spherically convergent beam of recirculating ions, a technique known as inertial electrostatic confinement (IEC). This study looks at several aspects of IEC devices, including measurements of the fusion rate of an IEC device with a wire mesh electrode cathode, and a solid titanium cathode. In addition, several computational studies were performed to explore the possibilities for IEC fusion. These include development of a 1D-1P …
A Multi-Modal Volumetric Microscope With Automated Sample Handling For Surveying Microbial Life In Liquid Samples, Nathan Oborny, Eugene Serabyn, J. Kent Wallace, Kurt Liewer, Manuel Bedrossian, Stephanie Rider, Chris Lindensmith, Jay Nadeau, Multiple Additional Authors
A Multi-Modal Volumetric Microscope With Automated Sample Handling For Surveying Microbial Life In Liquid Samples, Nathan Oborny, Eugene Serabyn, J. Kent Wallace, Kurt Liewer, Manuel Bedrossian, Stephanie Rider, Chris Lindensmith, Jay Nadeau, Multiple Additional Authors
Physics Faculty Publications and Presentations
In the study of microbial life, microscopy plays a unique role due to its ability to detect ordered structure, motility, and fluorescence signals. As such it has also recently gained attention in the context of searching for extant life on distant Solar System bodies bearing liquid water. In this paper we introduce a multimodal volumetric microscopy system for potential future spaceflight missions that combines digital holographic microscopy (DHM) and volume fluorescence imager (VFI), which are volumetric imaging methods that provide highresolution, high-throughput examination of liquid samples. DHM provides information on the absorption, morphology, and motility of imaged objects without requiring …
Transient Vision Loss Associated With Prefilled Aflibercept Syringes: A Case Series And Analysis Of Injection Force, Daniel J. Lee, Brittni A. Scruggs, Erik J. Sánchez, Merina Thomas, Ambar Faridi
Transient Vision Loss Associated With Prefilled Aflibercept Syringes: A Case Series And Analysis Of Injection Force, Daniel J. Lee, Brittni A. Scruggs, Erik J. Sánchez, Merina Thomas, Ambar Faridi
Physics Faculty Publications and Presentations
Purpose
To describe cases of significant vision loss after intravitreal aflibercept administration using prefilled syringes (PFS) and to study the relationships among syringe design, injection speed, and injection force.
Design
Retrospective case series and experimental study.
Participants
Twelve patients who received intravitreal aflibercept via PFS.
Methods
All retina specialists (n = 13) at Oregon Health & Science University and the Veterans Affairs Portland Medical Center were queried in December 2020 to report episodes of significant vision loss after aflibercept PFS use. Chart review was completed for all affected patients. Using a commercially available force measuring system, injection force was measured …
Biogeochemical Responses To Mixing Of Glacial Meltwater And Hot Spring Discharge In The Mount St. Helens Crater, Ashley Dubnick, Q. Faber, J. R. Hawkings, N. Bramall, B. C. Christner, Peter T. Doran, Jay Nadeau, C. Snyder, Multiple Additional Authors
Biogeochemical Responses To Mixing Of Glacial Meltwater And Hot Spring Discharge In The Mount St. Helens Crater, Ashley Dubnick, Q. Faber, J. R. Hawkings, N. Bramall, B. C. Christner, Peter T. Doran, Jay Nadeau, C. Snyder, Multiple Additional Authors
Physics Faculty Publications and Presentations
Environments where geothermal waters and glacier meltwater mix are common on Earth yet little is known about the biogeochemical processes that occur when hot, reduced geothermal water mixes with cold, oxidized glacial meltwater in natural systems. Mount St. Helens provides an ideal location to study the interaction between geothermal and glacier waters since the water sources, and their mixing environment in Step Creek, are exposed in the volcanic crater. We find that the two water sources contain distinct major ion, trace element, dissolved organic matter (DOM), and biological signatures. The hot spring contains high concentrations of biogeochemically reactive components (e.g., …
System Design For The Quantification Of Microbial Motility In Extreme Environments, Megan Marie Dubay
System Design For The Quantification Of Microbial Motility In Extreme Environments, Megan Marie Dubay
Dissertations and Theses
Motility of microorganisms is understudied but provides useful insights into their behavior. Organisms' ability to move autonomously changes how they interact with their environment--finding nutrients, interacting with other organisms, and avoiding unfavorable conditions. Understanding motility features can also be used to identify specific species, such as the identification of Vibrio cholerae in human samples. Motility might also be used as evidence of life existing in even the most extreme environments on Earth, and possibly beyond. Specialized microscopy systems can be required to examine the motility of microorganisms due to the nature of the environments to which the instruments are exposed. …
Characterizing The Single-Photon State: Quantum Physics Experiments With Single-Photon Sensitivity, Sheldon Lee Field
Characterizing The Single-Photon State: Quantum Physics Experiments With Single-Photon Sensitivity, Sheldon Lee Field
University Honors Theses
Coincidence-counting and spontaneous parametric downconversion are central to introductory quantum mechanical experimentation but have remained largely out of reach of undergraduate physics instructors. This thesis summarizes the theory behind light polarization, spontaneous parametric downconversion, birefringent refractive indices, and an affordable self-contained photon coincidence counting unit (CCU). A method for implementing a CCU to demonstrate downconversion is presented, and empirical results are provided.
An Integral Transform For Quantum Amplitudes, Jack C. Straton
An Integral Transform For Quantum Amplitudes, Jack C. Straton
Physics Faculty Publications and Presentations
The central impediment to reducing multidimensional integrals of transition amplitudes to analytic form, or at least to a fewer number of integral dimensions, is the presence of magnitudes of coordinate vector differences (square roots of polynomials) |x1−x2|2=x21−2x1x2cosθ+x2 √ in disjoint products of functions. Fourier transforms circumvent this by introducing a three-dimensional momentum integral for each of those products, followed in many cases by another set of integral transforms to move all of the resulting denominators into a single quadratic form in one denominator whose square my be completed. Gaussian transforms introduce a one-dimensional integral for each such product while squaring …
A Multi-City Urban Atmospheric Greenhouse Gas Measurement Data Synthesis, Logan E. Mitchell, John C. Lin, Lucy R. Hutyra, David R. Bowling, Ronald C. Cohen, Kenneth J. Davis, Elizabeth Digangi, Riley M. Duren, Andrew Rice, Multiple Additional Authors
A Multi-City Urban Atmospheric Greenhouse Gas Measurement Data Synthesis, Logan E. Mitchell, John C. Lin, Lucy R. Hutyra, David R. Bowling, Ronald C. Cohen, Kenneth J. Davis, Elizabeth Digangi, Riley M. Duren, Andrew Rice, Multiple Additional Authors
Physics Faculty Publications and Presentations
Urban regions emit a large fraction of anthropogenic emissions of greenhouse gases (GHG) such as carbon dioxide (CO2) and methane (CH4) that contribute to modern-day climate change. As such, a growing number of urban policymakers and stakeholders are adopting emission reduction targets and implementing policies to reach those targets. Over the past two decades research teams have established urban GHG monitoring networks to determine how much, where, and why a particular city emits GHGs, and to track changes in emissions over time. Coordination among these efforts has been limited, restricting the scope of analyses and insights. Here we present a …
Methodologies For Quantum Circuit And Algorithm Design At Low And High Levels, Edison Tsai
Methodologies For Quantum Circuit And Algorithm Design At Low And High Levels, Edison Tsai
Dissertations and Theses
Although the concept of quantum computing has existed for decades, the technology needed to successfully implement a quantum computing system has not yet reached the level of sophistication, reliability, and scalability necessary for commercial viability until very recently. Significant progress on this front was made in the past few years, with IBM planning to create a 1000-qubit chip by the end of 2023, and Google already claiming to have achieved quantum supremacy. Other major industry players such as Intel and Microsoft have also invested significant amounts of resources into quantum computing research.
Any viable computing system requires both hardware and …
Observation And Control Of Photoemission And Electric Field Enhancement Of Plasmonic Antennas Through Photoemission Electron Microscopy, Christopher M. Scheffler
Observation And Control Of Photoemission And Electric Field Enhancement Of Plasmonic Antennas Through Photoemission Electron Microscopy, Christopher M. Scheffler
Dissertations and Theses
Photoemission electron microscopy (PEEM) is an imaging method which uses electrons excited through the photoelectric effect to characterize a sample surface with nanometer-level resolution. In PEEM, a high intensity laser excites electrons from the surface of the material and electron optics are used to form an image from the intensity and spatial distribution of the photoemission from the sample. The goal of this research was to study and maximize light confinement, which was accomplished using plasmonic nanostructures. Surface plasmons represent oscillations in the electron density of a material and can occur along the transition interface between a metal and a …
Using Digital Holographic Microscopy To Characterize Vibrio's Chemotaxis, Jacqueline Acres, Eric Valentino
Using Digital Holographic Microscopy To Characterize Vibrio's Chemotaxis, Jacqueline Acres, Eric Valentino
Student Research Symposium
Vibrio alginolyticus is a marine bacterium that displays distinctive chemotactic behavior. Chemotaxis is the ability to move in response to a concentration gradient, either in the direction of nutrients or away from repellants. Vibrio's single, polar flagellum allows it to form a tight cloud in the presence of a chemoattractant. In this work, we experimentally characterize cloud sizes after both normal culture conditions and simulated microgravity using digital holographic microscopy or DHM. DHM allows visualization of volumetric samples by recording x,y,z and t information in holograms. Plane-by-plane reconstruction retrieves the z-plane information which can then by stitched together into hyperstacks …
Surface Plasmon Characterization In Ag Nanotriangles For Evaluation Of Fano Resonance Conditions, Nabila Islam
Surface Plasmon Characterization In Ag Nanotriangles For Evaluation Of Fano Resonance Conditions, Nabila Islam
Student Research Symposium
Surface plasmon polariton (SPP) is a collective oscillation of electrons and light at the metal -dielectric interface excited by the incident radiation on metal surface through the momentum matching conditions. The properties of SPPs and the resonance conditions are highly dependent on the confining materials and geometry of the confining nanostructure. The sensitivity of the surface plasmon resonance to the property of the confining materials made Surface plasmon resonance (SPR) sensors a central tool for biosensing. However, the frequency resolution of SPR sensors is typically limited by the broad resonance of the SPR mode. The resolution can be enhanced through …
Objective Crystallographic Symmetry Classifications Of A Noisy Crystal Pattern With Strong Fedorov-Type PseudoSymmetries And Its Optimal Image-Quality Enhancement, Peter Moeck
Physics Faculty Publications and Presentations
Statistically sound crystallographic symmetry classifications are obtained with information-theory-based methods in the presence of approximately Gaussian distributed noise. A set of three synthetic patterns with strong Fedorov-type pseudosymmetries and varying amounts of noise serve as examples. Contrary to traditional crystallographic symmetry classifications with an image processing program such as CRISP, the classification process does not need to be supervised by a human being and is free of any subjectively set thresholds in the geometric model selection process. This enables crystallographic symmetry classification of digital images that are more or less periodic in two dimensions (2D), also known as crystal …
Quantification Of Motility In Bacillus Subtilis At Temperatures Up To 84°C Using A Submersible Volumetric Microscope And Automated Tracking, Megan M. Dubay, Nikki Johnston, Mark Wronkiewicz, Jake Lee, Chris Lindensmith, Jay Nadeau
Quantification Of Motility In Bacillus Subtilis At Temperatures Up To 84°C Using A Submersible Volumetric Microscope And Automated Tracking, Megan M. Dubay, Nikki Johnston, Mark Wronkiewicz, Jake Lee, Chris Lindensmith, Jay Nadeau
Physics Faculty Publications and Presentations
We describe a system for high-temperature investigations of bacterial motility using a digital holographic microscope completely submerged in heated water. Temperatures above 90°C could be achieved, with a constant 5°C offset between the sample temperature and the surrounding water bath. Using this system, we observed active motility in Bacillus subtilis up to 66°C. As temperatures rose, most cells became immobilized on the surface, but a fraction of cells remained highly motile at distances of >100 μm above the surface. Suspended non-motile cells showed Brownian motion that scaled consistently with temperature and viscosity. A novel open-source automated tracking package was used …
Characterization Of High Mobility Channels For Use In Quantum Computing Devices, Payam Amin
Characterization Of High Mobility Channels For Use In Quantum Computing Devices, Payam Amin
Dissertations and Theses
Quantum computing promises computation that is fundamentally beyond the reach of classical computers. For the realization of a full-scale quantum computer, millions of quantum bits need to be fabricated on an integrated circuit and operated at cryogenic temperatures. Silicon and silicon-germanium based electron spin quantum bits have the advantage of leveraging decades of semiconductor industry knowledge for high volume manufacturability.
During the process development of any semiconductor device, material characterization is essential to understand and improve the process. Transmission electron microscopy is the only technique that could offer localized high spatial resolution characterization. In this work we have introduced two …
Effects Of Pore-Forming Peptides (Melittin And Magainin 2) On The Phospholipid Bilayer Interior, Elmukhtar Ehmed Alhatmi
Effects Of Pore-Forming Peptides (Melittin And Magainin 2) On The Phospholipid Bilayer Interior, Elmukhtar Ehmed Alhatmi
Dissertations and Theses
Antimicrobial peptides (AMPs) are one of the most promising solutions to drug-resistant bacteria. Melittin and magainin 2 are two of the most representative and extensively studied AMPs. In this research, I investigated the interaction of these two AMPs with three models of cell membranes: 80% POPC 20% POPG, 40%POPC 40% POPE and 20% POPG, and 80%POPC 20%POPG plus 30% mole fraction of cholesterol. Time-resolved fluorescence emission and fluorescence anisotropy decays of the fluorescent probe 1,6-diphenyl-1,3,5-hexatriene (DPH) were analyzed to determine the effects of AMPs on the bilayer headgroup packing and changes in the interior of the phospholipid bilayer during the …