Mathematics Commons^™

A Comprehensive, Multi-Scale Dynamical Model Of Erbb Receptor Signal Transduction In Human Mammary Epithelial Cells, Tomáš Helikar, Naomi Kochi, Bryan Kowal, Manjari Dimri, Mayumi Naramura, Srikumar M. Raja, Vimla Band, Hamid Band, Jim A. Rogers

Mathematics Faculty Publications

The non-receptor tyrosine kinase Src and receptor tyrosine kinase epidermal growth factor receptor (EGFR/ErbB1) have been established as collaborators in cellular signaling and their combined dysregulation plays key roles in human cancers, including breast cancer. In part due to the complexity of the biochemical network associated with the regulation of these proteins as well as their cellular functions, the role of Src in EGFR regulation remains unclear. Herein we present a new comprehensive, multi-scale dynamical model of ErbB receptor signal transduction in human mammary epithelial cells. This model, constructed manually from published biochemical literature, consists of 245 nodes representing proteins …

Sub-Riemannian Heat Kernels And Mean Curvature Flow Of Graphs, Luca Capogna, Giovanna Citti, Cosimo Senni Guidotti Magnani

Mathematics Sciences: Faculty Publications

We introduce a sub-Riemannian analogue of the Bence-Merriman-Osher algorithm (Merriman et al., 1992 [42]) and show that it leads to weak solutions of the horizontal mean curvature flow of graphs over sub-Riemannian Carnot groups. The proof follows the nonlinear semi-group theory approach originally introduced by L.C. Evans (1993) [27] in the Euclidean setting and is based on new results on the relation between sub-Riemannian heat flows of characteristic functions of subgraphs and the horizontal mean curvature of the corresponding graphs.

Periodic Modules Over Gorenstein Local Rings, Amanda Croll

Department of Mathematics: Dissertations, Theses, and Student Research

It is proved that the minimal free resolution of a module M over a Gorenstein local ring R is eventually periodic if, and only if, the class of M is torsion in a certain Z[t,t^{-1}] associated to R. This module, denoted (R), is the free Z[t,t^{-1}]-module on the isomorphism classes of finitely generated R-modules modulo relations reminiscent of those defining the Grothendieck group of R. The main result is a structure theorem for J(R) when R is a complete Gorenstein local ring; the link between periodicity and torsion stated above is a corollary.

Advisor: Srikanth Iyengar

Byu Computational Number Theory Research Group, Dr. Paul Jenkins

Journal of Undergraduate Research

The computational number theory group has clearly been a success, with students writing papers, giving conference presentations, winning prestigious national fellowships, and going off to strong PhD programs in mathematics. The weekly seminar has helped students learn presentation skills and learn more mathematics, and has provided a convenient entry point for new students interested in research. It is anticipated that the group will continue into the foreseeable future, and that students will continue to benefit from the allocated resources.

Disconjugacy And Differentiation For Solutions Of Boundary Value Problems For Second-Order Dynamic Equations On A Time Scale, Jeffrey W. Lyons

Mathematics Colloquium Series

On the specific time scale—given as integer multiples of a fixed, positive real number h—and under certain conditions, solutions of a nonlinear second-order dynamic equation with conjugate boundary conditions are differentiated with respect to the boundary values and delta differentiated with respect to the boundary points. Lyons will also present two corollaries of the result.

Regularity For Solutions To Parabolic Systems And Nonlocal Minimization Problems, Joe Geisbauer

Department of Mathematics: Dissertations, Theses, and Student Research

The goal of this dissertation is to contribute to both the nonlocal and local settings of regularity within the calculus of variations. We provide analogues of higher differentiability results in the context of Besov spaces for minimizers of nonlocal functionals. We also establish the Holder continuity of solutions to a system of parabolic partial differential equations.

Advisor: Mikil Foss

Tracial Rokhlin Property And Non-Commutative Dimensions, Qingyun Wang

All Theses and Dissertations (ETDs)

This dissertation focuses on finite group actions with the tracial Rokhlin property and the structure of the corresponding crossed products. It consists of two major parts. For the first part, we study several different aspects of finite group actions with certain versions of the Rokhlin property. We are able to give an explicit characterization of product-type actions with the tracial Rokhlin property or strict Rokhlin property. We also show that, in good circumstances, the actions with the tracial Rokhlin property are generic.

In the second portion of this dissertation, we introduce the weak tracial Rokhlin property for actions on non-simple …

The Schwinger Action Principle And Its Applications To Quantum Mechanics, Paul Bracken

School of Mathematical & Statistical Sciences Faculty Publications

No abstract provided.

Single Exhaled Breath Metabolomic Analysis Identifies Unique Breathprint In Patients With Acute Decompensated Heart Failure, Michael A. Samara, W.H. Wilson Tang, Frank Cikach Jr., Zeynep Gul, Lily Tranchito, Kelly M. Paschke, Jamie Viterna, Yuping Wu, Daniel Laskowski, Raed A. Dweik

Mathematics and Statistics Faculty Publications

Acute decompensated heart failure (ADHF) is the most common indication for hospital admission, particularly in the elderly, yet the identification of those with impending decompensation using conventional clinical methods is unreliable and frequently leaves insufficient lag time for therapeutic interventions (1). Exhaled breath constitutes a complex mixture of hundreds of volatile organic compounds (VOCs) that could potentially be used as a safe and noninvasive method of diagnostic and therapeutic monitoring (2). Previous research studies have identified elevated acetone, pentane, and nitric oxide levels in exhaled breath in the setting of HF correlated with disease severity (3–5). Selected ion-flow tube mass-spectrometry …

Finances & Algebra Too!, Anne J. Catlla, Jonathan Foster, Charlene Frazier

Arthur Vining Davis High Impact Fellows Projects

The focus of this project is to provide an application-based approach to teaching algebra 2. Students will study algebraic concepts and functions through the lens of personal finance. After each unit of study, students will complete a financial application project that will go into each student’s “financial” portfolio.

Towards A Better Understanding Of Space-Time Causality: Kolmogorov Complexity And Causality As A Matter Of Degree, Vladik Kreinovich, Andres Ortiz

Departmental Technical Reports (CS)

Space-time causality is one of the fundamental notions of modern physics; however, it is difficult to define in observational physical terms. Intuitively, the fact that a space-time event e=(t,x) can causally influence an event e'=(t',x') means that what we do in the vicinity of e changes what we observe at e'. If we had two copies of the Universe, we could perform some action at e in one copy but not in another copy; if we then observe the difference at e', this would be an indication of causality. However, we only observe one Universe, in which we either perform …

Mapcores 2012-2013 Assessment Report, Kristen Nairn, Pamela L. Bacon, Jim Crumley, Lynn Ziegler

MapCores Faculty Publications

This is a report showing the assessment results for the MapCores (MAthematics, Physics, COmputer science REsearch Scholars) program at the College of Saint Benedict. Started in 2009, MapCores is a cohort-based program designed to increase women's interest and achievement in mathematics, physics, computer science and engineering. The report was submitted for the National Science Foundation grant number 0965705.

Self-Directed Learning Readiness And Self-Determination For Selected Rehabilitation Professional Students: The Impact Of Clinical Education, Shelley S. Payne, Peter Rundquist, William V. Harper, Julie Gahimer

Mathematics Faculty Scholarship

In a time of rapidly changing medical information, practitioners must have learning skills that enable them to be effective life-long learners. A part of an examination of a final clinical internship for rehabilitation professionals was a pre-post measure of learner self-direction and self-determination. Two instruments, the Self-Directed Learning Readiness Scale (SDLRS) and the Academic Motivation Scale (AMS- reported as Self-Determination Index (SDI) were used with a sample of Doctorate of Physical Therapy (DPT) and Master of Occupational Therapy (MOT) students. Pre-testing occurred just prior to and post-testing just after the subjects’ final clinical assignments. Both groups increased mean scores from …

A Borsuk-Ulam Equivalent That Directly Implies Sperner's Lemma, Kathryn L. Nyman, Francis Su

All HMC Faculty Publications and Research

We show that Fan’s 1952 lemma on labelled triangulations of the n-sphere with n + 1 labels is equivalent to the Borsuk–Ulam theorem. Moreover, unlike other Borsuk–Ulam equivalents, we show that this lemma directly implies Sperner’s Lemma, so this proof may be regarded as a combinatorial version of the fact that the Borsuk–Ulam theorem implies the Brouwer fixed-point theorem, or that the Lusternik–Schnirelmann–Borsuk theorem implies the KKM lemma.

Quantitative Approaches To Sustainability Seminars, Rachel Levy

All HMC Faculty Publications and Research

How can mathematicians contribute to education of about sustainability? Mathematicians study climate change, energy-related technologies, models of energy availability, production and consumption, and even the political and social aspects of sustainable legislation and practices. However, at this point, few courses on sustainability can be found in math department offerings. When we consider problems that our current and future students will face, energy sustainability certainly seems important. But how many of these ideas reach our classrooms?

[Sabbatical Report], Alex Lebedinsky

Sabbatical Reports

During the sabbatical leave I collaborated with Dr. Ferhan Atici of the Mathematics department on a new theory of mathematical modeling called Time Scale Calculus (TSC). Dr. Atici and I are also working on another article (titled) "Cagan-type rational expectation model on complex discrete time domains."

Voter Compatibility In Interval Societies, Rosalie J. Carlson

HMC Senior Theses

In an interval society, voters are represented by intervals on the real line, corresponding to their approval sets on a linear political spectrum. I imagine the society to be a representative democracy, and ask how to choose members of the society as representatives. Following work in mathematical psychology by Coombs and others, I develop a measure of the compatibility (political similarity) of two voters. I use this measure to determine the popularity of each voter as a candidate. I then establish local “agreeability” conditions and attempt to find a lower bound for the popularity of the best candidate. Other results …

Imprecise Probabilities In Engineering Analyses, Michael Beer, Scott Ferson, Vladik Kreinovich

Departmental Technical Reports (CS)

Probabilistic uncertainty and imprecision in structural parameters and in environmental conditions and loads are challenging phenomena in engineering analyses. They require appropriate mathematical modeling and quantification to obtain realistic results when predicting the behavior and reliability of engineering structures and systems. But the modeling and quantification is complicated by the characteristics of the available information, which involves, for example, sparse data, poor measurements and subjective information. This raises the question whether the available information is sufficient for probabilistic modeling or rather suggests a set-theoretical approach. The framework of imprecise probabilities provides a mathematical basis to deal with these problems which …

Spock, Euler, And Madison: Graph Theory In The Classroom, Michael Buhler

Undergraduate Honors Capstone Projects

This work is an attempt to accomplish two main objectives. First is to encourage secondary students to engage in the kinds of mathematical reasoning skills that will be necessary to them when they move to college math classes. My experience in college, along with that of many others is that "school math," with its obsession with calculations and memorization, is dreadfully insufficient in preparing students for the proof and reasoning-based classes they will face in high school. This is an attempt to integrate some of those reasoning skills into high school courses using graph theory as a vehicle.

The second …

The Use Of Statistics In Experimental Physics, Thomas J. Pfaff, Maksim Sipos, M. C. Sullivan, B. G. Thompson, Max Tran

Publications and Research

Most mathematicians are aware of the importance of statistics in biological sciences, business, and economics, but are less aware that statistics is used every day in experimental physics. This paper gives three interesting examples of how statistics plays a vital role in physics. These examples use the basic statistical tools of residuals analysis and goodness of fit.

Measuring A Circle: A Math Lesson For Grades 5-10, Robert C. Moore

Faculty Publications

This article is designed to promote teaching methods that engage students in active learning and result in deep conceptual understanding by offering a sample lesson to help students (grades 5-10, ages 10-15) answer questions about and gain a deeper understanding of how to measure the circumference and area of a circle.

Student Centered Mathematics In An Isolated Skill Environment-Constructivist Methods In Mathematics, Amy Katherine Sorenson

Mathematics Graduate Theses

"A research paper submitted to the Faculty of the Department of Mathematics in partial fulfillment of the requirements for the degree of Master of Science in Elementary and Middle Mathematics Education"

Improving Student Achievement Through Feedback, Jennifer L. Mchlachlan

Mathematics Graduate Theses

This paper reviews the current research that exists on feedback given to students in an educational setting. Questions examined were what characteristics make feedback effective, what are the effects on student achievement if feedback is available to students in a math classroom and does timing of the feedback given play a role in its effectiveness. Results showed that feedback is effective if it is descriptive, including both strengths and weaknesses. Feedback given in small doses throughout the learning process, so as not to overwhelm students, has also proven effective. The research shows that the effect of feedback on student achievement …

Volume 05, Ian Karamarkovich, Jessica Cox, Kyle Fowlkes, Allison Pawlowski, Kaitlin Major, Carrie Dunham, Kelsey Scheitlin, Kathryn Grayson, Ashley Johnson, Jennifer Nehrt, Kelsey Stolzenbach, Kristin Mcquarrie, Sara Nelson, Melisa Michelle, Jessica Sudlow, Perry Bason, Danielle Dmuchawski, Mariah Asbell, Matthew Sakach, Timothy Smith Jr., Annaliese Troxell, T. Dane Summerell, Sarah Ganrude, Malina Rutherford, Hannah Hopper, John Berry Jr., James Early, Colleen Festa, Chelsea D. Taylor, Michelle Maddox, Kaitlyn Smith, Sarah Schu, Cabell Edmunds, Katherine Grayson, Kayla Tornai

Incite: The Journal of Undergraduate Scholarship

Introduction from Dean Dr. Charles Ross

The Tallis House as an Extension of Emily Tallis in McEwan's Atonement by Ian Karamarkovich

Graphic Design by Jessica Cox

Graphic Design by Kyle Fowlkes

Graphic Design by Allison Pawlowski

Incorporating Original Research in The Classroom: A Case Study Analyzing the Influence of the Chesapeake Bay on Local Temperatures by Kaitlin Major, Carrie Dunham and Dr. Kelsey Scheitlin

Graphic Design by Kathryn Grayson

Graphic Design by Ashley Johnson

Facing the Music: Environmental Impact Assessment of Building A Concert Hall on North Campus by Jennifer Nehrt, Kelsey Stolzenbach And Dr. Kelsey Scheitlin

Art by Kristin …

Combinatorial Pooling Enables Selective Sequencing Of The Barley Gene Space, Stefano Lonardi, Denisa Duma, Matthew Alpert, Francesca Cordero, Marco Beccuti, Prasanna R. Bhat, Yonghui Wu, Gianfranco Ciardo, Burair Alsaihati, Steve Wanamaker, Josh Resnik, Serdar Bozdag, Ming-Cheng Luo, Timothy J. Close

Mathematics, Statistics and Computer Science Faculty Research and Publications

For the vast majority of species – including many economically or ecologically important organisms, progress in biological research is hampered due to the lack of a reference genome sequence. Despite recent advances in sequencing technologies, several factors still limit the availability of such a critical resource. At the same time, many research groups and international consortia have already produced BAC libraries and physical maps and now are in a position to proceed with the development of whole-genome sequences organized around a physical map anchored to a genetic map. We propose a BAC-by-BAC sequencing protocol that combines combinatorial pooling design and …

Weighted Shifts Of Finite Multiplicity, Daniel S. Sievewright

Dissertations

We will discuss the structure of weighted shift operators on a separable, infinite dimensional, complex Hilbert space. A weighted shift is said to have multiplicity n when all the weights are n x n matrices. To study these weighted shifts, we will investigate which operators can belong to the Deddens algebras and spectral radius algebras, which can be quite large. This will lead to the necessary and sufficient conditions for these algebras to have a nontrivial invariant subspace.

Direct Eit Reconstructions Of Complex Admittivities On A Chest-Shaped Domain In 2-D, Sarah J. Hamilton, Jennifer L. Mueller

Mathematics, Statistics and Computer Science Faculty Research and Publications

Electrical impedance tomography (EIT) is a medical imaging technique in which current is applied on electrodes on the surface of the body, the resulting voltage is measured, and an inverse problem is solved to recover the conductivity and/or permittivity in the interior. Images are then formed from the reconstructed conductivity and permittivity distributions. In the 2-D geometry, EIT is clinically useful for chest imaging. In this work, an implementation of a D-bar method for complex admittivities on a general 2-D domain is presented. In particular, reconstructions are computed on a chest-shaped domain for several realistic phantoms including a simulated pneumothorax, …

Age-Specific Signatures Of Glioblastoma At The Genomic, Genetic, And Epigenetic Levels, Serdar Bozdag, Aiguo Li, Gregory Riddick, Yuri Kotliarov, Mehmet Baysan, Fabio M. Iwamoto, Margaret C. Cam, Svetlana Kotliarova, Howard A. Fine

Mathematics, Statistics and Computer Science Faculty Research and Publications

Age is a powerful predictor of survival in glioblastoma multiforme (GBM) yet the biological basis for the difference in clinical outcome is mostly unknown. Discovering genes and pathways that would explain age-specific survival difference could generate opportunities for novel therapeutics for GBM. Here we have integrated gene expression, exon expression, microRNA expression, copy number alteration, SNP, whole exome sequence, and DNA methylation data sets of a cohort of GBM patients in The Cancer Genome Atlas (TCGA) project to discover age-specific signatures at the transcriptional, genetic, and epigenetic levels and validated our findings on the REMBRANDT data set. We found major …

Repeated Changes In Reported Sexual Orientation Identity Linked To Substance Use Behaviors In Youth, Miles Q. Ott, David Wypij, Heather L. Corliss, Margaret Rosario, Sari L. Reisner, Allegra R. Gordon, S. Bryn Austin

Statistical and Data Sciences: Faculty Publications

Purpose—Previous studies have found that sexual minority (e.g., lesbian, gay, bisexual) adolescents are at higher risk of substance use than heterosexuals, but few have examined how changes in sexual orientation over time may relate to substance use. We examined the associations between change in sexual orientation identity and marijuana use, tobacco use, and binge drinking in U.S. youth.

Methods—Prospective data from 10,515 U.S. youth ages 12-27 years in a longitudinal cohort study were analyzed using sexual orientation identity mobility measure M (frequency of change from 0 [no change] to 1 [change at every wave]) in up to five waves of …

2013 (Spring), University Of Dayton. Department Of Mathematics

Colloquia

Abstracts of the talks given at the 2013 Spring Colloquium.