Computer Sciences Commons^™

Development Of A Slab-Based Monte Carlo Proton Dose Algorithm With A Robust Material-Dependent Nuclear Halo Model, John Wesley Chapman Jr

LSU Doctoral Dissertations

Pencil beam algorithms (PBAs) are often utilized for dose calculation in proton therapy treatment planning because they are fast and accurate under most conditions. However, as discussed in Chapman et al (2017), the accuracy of a PBA can be limited under certain conditions because of two major assumptions: (1) the central-axis semi-infinite slab approximation; and, (2) the lack of material dependence in the nuclear halo model. To address these limitations, we transported individual protons using a class II condensed history Monte Carlo and added a novel energy loss method that scaled the nuclear halo equation in water to arbitrary geometry. …

Quantitative Electroencephalography For Detecting Concussions, Sara Krehbiel, Kathy Hoke, Joanna Wares

Biology and Medicine Through Mathematics Conference

No abstract provided.

Combinatorial Proofs Of Identities Of Alzer And Prodinger And Some Generalizations, John Engbers, Christopher Stocker

Mathematics, Statistics and Computer Science Faculty Research and Publications

We provide combinatorial proofs of identities published by Alzer and Prodinger. These identities include that for integers b, n, and r with b ≥ 1 and n − 1 ≥ r ≥ 0 we have

and for integers b, n, and r with b ≥ 0 and n − 1 ≥ r ≥ 0 we have

Our combinatorial proofs generalize squares to sth powers, and involve generalized Eulerian numbers and generalized Delannoy numbers.

Dynamic Statistical Models For Pyroclastic Density Current Generation At Soufrière Hills Volcano, Robert L. Wolpert, Elaine T. Spiller, Eliza S. Calder

Mathematics, Statistics and Computer Science Faculty Research and Publications

To mitigate volcanic hazards from pyroclastic density currents, volcanologists generate hazard maps that provide long-term forecasts of areas of potential impact. Several recent efforts in the field develop new statistical methods for application of flow models to generate fully probabilistic hazard maps that both account for, and quantify, uncertainty. However, a limitation to the use of most statistical hazard models, and a key source of uncertainty within them, is the time-averaged nature of the datasets by which the volcanic activity is statistically characterized. Where the level, or directionality, of volcanic activity frequently changes, e.g., during protracted eruptive episodes, or at …

Impacts Of Simultaneous Multislice Acquisition On Sensitivity And Specificity In Fmri, Benjamin B. Risk, Mary C. Kociuba, Daniel B. Rowe

Mathematics, Statistics and Computer Science Faculty Research and Publications

Simultaneous multislice (SMS) imaging can be used to decrease the time between acquisition of fMRI volumes, which can increase sensitivity by facilitating the removal of higher-frequency artifacts and boosting effective sample size. The technique requires an additional processing step in which the slices are separated, or unaliased, to recover the whole brain volume. However, this may result in signal “leakage” between aliased locations, i.e., slice “leakage,” and lead to spurious activation (decreased specificity). SMS can also lead to noise amplification, which can reduce the benefits of decreased repetition time. In this study, we evaluate the original slice-GRAPPA (no leak block) …

The Kumaraswamy Marshall-Olkin Log-Logistic Distribution With Application, Selen Cakmakyapan, Gamze Ozel, Yehia Mousa Hussein El Gebaly, Gholamhossein G. Hamedani

Mathematics, Statistics and Computer Science Faculty Research and Publications

In this paper, we define and study a new lifetime model called the Kumaraswamy Marshall-Olkin log-logistic distribution. The new model has the advantage of being capable of modeling various shapes of aging and failure criteria. The new model contains some well-known distributions as special cases such as the Marshall-Olkin log-logistic, log-logistic, lomax, Pareto type II and Burr XII distributions. Some of its mathematical properties including explicit expressions for the quantile and generating functions, ordinary moments, skewness, kurtosis are derived. The maximum likelihood estimators of the unknown parameters are obtained. The importance and flexibility of the new model is proved empirically …

Multi Self-Adapting Particle Swarm Optimization Algorithm (Msapso)., Gerhard Koch

Electronic Theses and Dissertations

The performance and stability of the Particle Swarm Optimization algorithm depends on parameters that are typically tuned manually or adapted based on knowledge from empirical parameter studies. Such parameter selection is ineffectual when faced with a broad range of problem types, which often hinders the adoption of PSO to real world problems. This dissertation develops a dynamic self-optimization approach for the respective parameters (inertia weight, social and cognition). The effects of self-adaption for the optimal balance between superior performance (convergence) and the robustness (divergence) of the algorithm with regard to both simple and complex benchmark functions is investigated. This work …

Preservice Mathematics Teachers' Conceptions And Enactments Of Modeling Standards, Hyunyi Jung, Jill Newton

Mathematics, Statistics and Computer Science Faculty Research and Publications

Mathematical modeling has been highlighted recently as Common Core State Standards for Mathematics [CCSSM] included Model with Mathematics as one of the Standards for Mathematical Practices [SMP] and a modeling strand in the high school standards. This common aspect of standards across most states in the U.S. intended by CCSSM authors and policy makers seems to mitigate the diverse notions of mathematical modeling. When we observed secondary mathematics preservice teachers [PSTs] who learned about the SMP and used CCSSM modeling standards to plan and enact lessons, however, we noted differences in their interpretations and enactments of the standards, despite their …

Characterizations And Infinite Divisibility Of Certain Recently Introduced Distributions Iv, Gholamhossein G. Hamedani

Mathematics, Statistics and Computer Science Faculty Research and Publications

Certain characterizations of recently proposed univariate continuous distributions are presented in different directions. This work contains a good number of reintroduced distributions and may serve as a source of preventing the reinvention and/or duplication of the existing distributions in the future.

Physical Applications Of The Geometric Minimum Action Method, George L. Poppe Jr.

Dissertations, Theses, and Capstone Projects

This thesis extends the landscape of rare events problems solved on stochastic systems by means of the \textit{geometric minimum action method} (gMAM). These include partial differential equations (PDEs) such as the real Ginzburg-Landau equation (RGLE), the linear Schroedinger equation, along with various forms of the nonlinear Schroedinger equation (NLSE) including an application towards an ultra-short pulse mode-locked laser system (MLL).

Additionally we develop analytical tools that can be used alongside numerics to validate those solutions. This includes the use of instanton methods in deriving state transitions for the linear Schroedinger equation and the cubic diffusive NLSE.

These analytical solutions are …

Analysis Of 2016-17 Major League Soccer Season Data Using Poisson Regression With R, Ian D. Campbell

Undergraduate Theses and Capstone Projects

To the outside observer, soccer is chaotic with no given pattern or scheme to follow, a random conglomeration of passes and shots that go on for 90 minutes. Yet, what if there was a pattern to the chaos, or a way to describe the events that occur in the game quantifiably. Sports statistics is a critical part of baseball and a variety of other of today’s sports, but we see very little statistics and data analysis done on soccer. Of this research, there has been looks into the effect of possession time on the outcome of a game, the difference …

Cognitive Virtual Admissions Counselor, Kumar Raja Guvindan Raju, Cory Adams, Raghuram Srinivas

SMU Data Science Review

Abstract. In this paper, we present a cognitive virtual admissions counselor for the Master of Science in Data Science program at Southern Methodist University. The virtual admissions counselor is a system capable of providing potential students accurate information at the time that they want to know it. After the evaluation of multiple technologies, Amazon’s LEX was selected to serve as the core technology for the virtual counselor chatbot. Student surveys were leveraged to collect and generate training data to deploy the natural language capability. The cognitive virtual admissions counselor platform is currently capable of providing an end-to-end conversational dialog to …

Understanding Natural Keyboard Typing Using Convolutional Neural Networks On Mobile Sensor Data, Travis Siems

Computer Science and Engineering Theses and Dissertations

Mobile phones and other devices with embedded sensors are becoming increasingly ubiquitous. Audio and motion sensor data may be able to detect information that we did not think possible. Some researchers have created models that can predict computer keyboard typing from a nearby mobile device; however, certain limitations to their experiment setup and methods compelled us to be skeptical of the models’ realistic prediction capability. We investigate the possibility of understanding natural keyboard typing from mobile phones by performing a well-designed data collection experiment that encourages natural typing and interactions. This data collection helps capture realistic vulnerabilities of the security …

Prediction Of Lncrna-Disease Associations Based On Inductive Matrix Completion, Chengqian Lu, Mengyun Yang, Feng Luo, Fang-Xiang Wu, Min Li, Yi Pan, Yaohang Li, Jianxin Wang

Computer Science Faculty Publications

Motivation: Accumulating evidences indicate that long non-coding RNAs (lncRNAs) play pivotal roles in various biological processes. Mutations and dysregulations of lncRNAs are implicated in miscellaneous human diseases. Predicting lncRNA–disease associations is beneficial to disease diagnosis as well as treatment. Although many computational methods have been developed, precisely identifying lncRNA–disease associations, especially for novel lncRNAs, remains challenging.

Results: In this study, we propose a method (named SIMCLDA) for predicting potential lncRNA– disease associations based on inductive matrix completion. We compute Gaussian interaction profile kernel of lncRNAs from known lncRNA–disease interactions and functional similarity of diseases based on disease–gene and gene–gene onotology …

Supporting Accurate Interpretation Of Self-Administered Medical Test Results For Mobile Health: Assessment Of Design, Demographics, And Health Condition, Jess C. Hohenstein, Eric P.S. Baumer, Lindsay Reynolds, Elizabeth L. Murnane, Dakota O'Dell, Seoho Lee, Shion Guha, Yu Qi, Erin Rieger, Geri K. Gay

Mathematics, Statistics and Computer Science Faculty Research and Publications

Background: Technological advances in personal informatics allow people to track their own health in a variety of ways, representing a dramatic change in individuals’ control of their own wellness. However, research regarding patient interpretation of traditional medical tests highlights the risks in making complex medical data available to a general audience.

Objective: This study aimed to explore how people interpret medical test results, examined in the context of a mobile blood testing system developed to enable self-care and health management.

Methods: In a preliminary investigation and main study, we presented 27 and 303 adults, respectively, with hypothetical results from several …

Predicting The Next Us President By Simulating The Electoral College, Boyan Kostadinov

Publications and Research

We develop a simulation model for predicting the outcome of the US Presidential election based on simulating the distribution of the Electoral College. The simulation model has two parts: (a) estimating the probabilities for a given candidate to win each state and DC, based on state polls, and (b) estimating the probability that a given candidate will win at least 270 electoral votes, and thus win the White House. All simulations are coded using the high-level, open-source programming language R. One of the goals of this paper is to promote computational thinking in any STEM field by illustrating how probabilistic …

The Accuracy, Fairness, And Limits Of Predicting Recidivism, Julie Dressel, Hany Farid

Dartmouth Scholarship

Algorithms for predicting recidivism are commonly used to assess a criminal defendant’s likelihood of committing a crime. These predictions are used in pretrial, parole, and sentencing decisions. Proponents of these systems argue that big data and advanced machine learning make these analyses more accurate and less biased than humans. We show, however, that the widely used commercial risk assessment software COMPAS is no more accurate or fair than predictions made by people with little or no criminal justice expertise. We further show that a simple linear predictor provided with only two features is nearly equivalent to COMPAS with its 137 …

A Patient-Specific Treatment Model For Graves’ Hyperthyroidism, Balamurugan Pandiyan, Stephen J. Merrill, Flavia Di Bari, Alessandro Antonelli, Salvatore Benvenga

Mathematics, Statistics and Computer Science Faculty Research and Publications

Background: Graves’ is disease an autoimmune disorder of the thyroid gland caused by circulating anti-thyroid receptor antibodies (TRAb) in the serum. TRAb mimics the action of thyroid stimulating hormone (TSH) and stimulates the thyroid hormone receptor (TSHR), which results in hyperthyroidism (overactive thyroid gland) and goiter. Methimazole (MMI) is used for hyperthyroidism treatment for patients with Graves’ disease.

Methods: We have developed a model using a system of ordinary differential equations for hyperthyroidism treatment with MMI. The model has four state variables, namely concentration of MMI (in mg/L), concentration of free thyroxine - FT4 (in pg/mL), and concentration of TRAb …

Regrets, I'Ve Had A Few: When Regretful Experiences Do (And Don't) Compel Users To Leave Facebook, Shion Guha, Eric P.S. Baumer, Geri K. Gay

Mathematics, Statistics and Computer Science Faculty Research and Publications

Previous work has explored regretful experiences on social media. In parallel, scholars have examined how people do not use social media. This paper aims to synthesize these two research areas and asks: Do regretful experiences on social media influence people to (consider) not using social media? How might this influence differ for different sorts of regretful experiences? We adopted a mixed methods approach, combining topic modeling, logistic regressions, and contingency analysis to analyze data from a web survey with a demographically representative sample of US internet users (n=515) focusing on their Facebook use. We found that experiences that arise because …

Models As Weapons: Review Of Weapons Of Math Destruction: How Big Data Increases Inequality And Threatens Democracy By Cathy O’Neil (2016), Samuel L. Tunstall

Numeracy

Cathy O’Neil. 2016. Weapons of Math Destruction: How Big Data Increases Inequality and Threatens Democracy (New York, NY: Crown) 272 pp. ISBN 978-0553418811.

Accessible to a wide readership, Cathy O’Neil’s Weapons of Math Destruction: How Big Data Increases Inequality and Threatens Democracy provides a lucid yet alarming account of the extensive reach of mathematical models in influencing all of our lives. With a particular eye towards social justice, O’Neil not only warns modelers to be cognizant of the effects of their work on real people—especially vulnerable groups who have less power to fight back—but also encourages laypersons to take initiative …

Crosstalk Among Lncrnas, Micrornas And Mrnas In The Muscle ‘Degradome’ Of Rainbow Trout, Bam Paneru, Ali Ali, Rafet Al-Tobasei, Brett Kenney, Mohamed Salem

Faculty & Staff Scholarship

In fish, protein-coding and noncoding genes involved in muscle atrophy are not fully characterized. In this study, we characterized coding and noncoding genes involved in gonadogenesis-associated muscle atrophy, and investigated the potential functional interplay between these genes. Using RNA- Seq, we compared expression pattern of mRNAs, long noncoding RNAs (lncRNAs) and microRNAs of atrophying skeletal muscle from gravid females and control skeletal muscle from age-matched sterile individuals. A total of 852 mRNAs, 1,160 lncRNAs and 28 microRNAs were differentially expressed (DE) between the two groups. Muscle atrophy appears to be mediated by many genes encoding ubiquitin- proteasome system, autophagy related …

Genome-Wide Association Analysis With A 50k Transcribed Gene Snp-Chip Identifies Qtl Affecting Muscle Yield In Rainbow Trout, Mohamed Salem, Rafet Al-Tobasei, Ali Ali, Daniela Lourenco, Guangtu Gao, Yniv Palti, Brett Kenney, Timothy D. Leeds

Faculty & Staff Scholarship

Detection of coding/functional SNPs that change the biological function of a gene may lead to identification of putative causative alleles within QTL regions and discovery of genetic markers with large effects on phenotypes. This study has two-fold objectives, first to develop, and validate a 50K transcribed gene SNP-chip using RNA-Seq data. To achieve this objective, two bioinformatics pipelines, GATK and SAMtools, were used to identify ∼21K transcribed SNPs with allelic imbalances associated with important aquaculture production traits including body weight, muscle yield, muscle fat content, shear force, and whiteness in addition to resistance/susceptibility to bacterial cold-water disease (BCWD). SNPs ere …

Integrated Analysis Of Lncrna And Mrna Expression In Rainbow Trout Families Showing Variation In Muscle Growth And Fillet Quality Traits, Ali Ali, Rafet Al-Tobasei, Brett Kenney, Timothy D. Leeds, Mohamed Salem

Faculty & Staff Scholarship

Muscle yield and quality traits are important for the aquaculture industry and consumers. Genetic selection for these traits is difficult because they are polygenic and result from multifactorial interactions. To study the genetic architecture of these traits, phenotypic characterization of whole body weight (WBW), muscle yield, fat content, shear force and whiteness were measured in ~500 fish representing 98 families from a growth-selected line. RNA-Seq was used to sequence the muscle transcriptome of different families exhibiting divergent phenotypes for each trait. We have identified 240 and 1,280 differentially expressed (DE) protein-coding genes and long noncoding RNAs (lncRNAs), respectively, in fish …

Adverse Event Detection By Integrating Twitter Data And Vaers, Junxiang Wang, Liang Zhao, Yanfang Ye, Yuji Zhang

Faculty & Staff Scholarship

Background: Vaccinehasbeenoneofthemostsuccessfulpublichealthinterventionstodate.However,vaccines are pharmaceutical products that carry risks so that many adverse events (AEs) are reported after receiving vaccines. Traditional adverse event reporting systems suffer from several crucial challenges including poor timeliness. This motivates increasing social media-based detection systems, which demonstrate successful capability to capture timely and prevalent disease information. Despite these advantages, social media-based AE detection suffers from serious challenges such as labor-intensive labeling and class imbalance of the training data.

Results: Totacklebothchallengesfromtraditionalreportingsystemsandsocialmedia,weexploittheircomplementary strength and develop a combinatorial classification approach by integrating Twitter data and the Vaccine Adverse Event Reporting System (VAERS) information aiming to identify potential AEs after …

Mechanism Design, Matching Theory And The Stable Roommates Problem, Yashaswi Mohanty

Honors Theses

This thesis consists of two independent albeit related chapters. The first chapter introduces concepts from mechanism design and matching theory, and discusses potential applications of this theory, particularly in relation to dorm allocations in colleges. The second chapter investigates a subset of the dorm allocation problem, namely that of matching roommates. In particular, the paper looks at the probability of solvability of random instances of the stable roommates game under the condition that preferences are not completely random and exogenous but endogenously determined through a dependence on room choice. These probabilities are estimated using Monte-Carlo simulations and then compared with …

Type I General Exponential Class Of Distributions, Gholamhossein G. Hamedani, Haitham M. Yousof, Mahdi Rasekhi, Morad Alizadeh, Seyed Morteza Najibi

Mathematics, Statistics and Computer Science Faculty Research and Publications

We introduce a new family of continuous distributions and study the mathematical properties of the new family. Some useful characterizations based on the ratio of two truncated moments and hazard function are also presented. We estimate the model parameters by the maximum likelihood method and assess its performance based on biases and mean squared errors in a simulation study framework.

Cluster-Based Network Proximities For Arbitrary Nodal Subsets, Kenneth S. Berenhaut, Peter S. Barr, Alyssa M. Kogel, Ryan L. Melvin

Faculty & Staff Scholarship

The concept of a cluster or community in a network context has been of considerable interest in a variety of settings in recent years. In this paper, employing random walks and geodesic distance, we introduce a unified measure of cluster-based proximity between nodes, relative to a given subset of interest. The inherent simplicity and informativeness of the approach could make it of value to researchers in a variety of scientific fields. Applicability is demonstrated via application to clustering for a number of existent data sets (including multipartite networks). We view community detection (i.e. when the full set of network nodes …

Automated Tree-Level Forest Quantification Using Airborne Lidar, Hamid Hamraz

Theses and Dissertations--Computer Science

Traditional forest management relies on a small field sample and interpretation of aerial photography that not only are costly to execute but also yield inaccurate estimates of the entire forest in question. Airborne light detection and ranging (LiDAR) is a remote sensing technology that records point clouds representing the 3D structure of a forest canopy and the terrain underneath. We present a method for segmenting individual trees from the LiDAR point clouds without making prior assumptions about tree crown shapes and sizes. We then present a method that vertically stratifies the point cloud to an overstory and multiple understory tree …

Modeling And Mapping Location-Dependent Human Appearance, Zachary Bessinger

Theses and Dissertations--Computer Science

Human appearance is highly variable and depends on individual preferences, such as fashion, facial expression, and makeup. These preferences depend on many factors including a person's sense of style, what they are doing, and the weather. These factors, in turn, are dependent upon geographic location and time. In our work, we build computational models to learn the relationship between human appearance, geographic location, and time. The primary contributions are a framework for collecting and processing geotagged imagery of people, a large dataset collected by our framework, and several generative and discriminative models that use our dataset to learn the relationship …

Using The Qbest Equation To Evaluate Ellagic Acid Safety Data: Generating A Qnoael With Confidence Levels From Disparate Literature, Cynthia Rose Dickerson

Theses and Dissertations--Pharmacy

QBEST, a novel statistical method, can be applied to the problem of estimating the No Observed Adverse Effect Level (NOAEL or QNOAEL) of a New Molecular Entity (NME) in order to anticipate a safe starting dose for beginning clinical trials. The NOAEL from QBEST (called the QNOAEL) can be calculated using multiple disparate studies in the literature and/or from the lab. The QNOAEL is similar in some ways to the Benchmark Dose Method (BMD) used widely in toxicological research, but is superior to the BMD in some ways. The QNOAEL simulation generates an intuitive curve that is comparable to the …