Organic Chemistry Commons^™

Heterocyclic Syntheses Utilizing Aryl Cyanates, Joseph Eugene Drumm

Masters Theses

No abstract provided.

Naphthalene-2,3-Dialdehyde: A Synthon To 7,9-Polymethylene-8h-Cyclohepta[B]Naphthalene-8-One And A Study Of Their Aromaticity, Edward O. Crapps

Dissertations

This report describes the synthesis of naphthalene-2,3-dialdehyde, and an analytical method for determining its purity by thin layer chromatography. Subsequently, the dialdehyde was condensed with various cyclic ketones to generate a series of polymethylene bridged naphthotropones. It was found that planarity and aromaticity increase with the size of the methylene bridge, although, the bridge must contain six or more methylene groups for the latter to be true. The claim for aromaticity is supported by NMR and IR data, which indicates the positive charge for a perchlorate cation salt is delocalized over the naphthalene and tropone ring system. Furthermore, from the …

Cationic And Anionic Micellar Catalyzed Hydrolysis Of Hydroxamic Acids, Douglas Eugene Conran

Masters Theses

The hydrolysis of octanohydroxamic and N-methyloctanohydroxamic acids in the presence of cationic and anionic micelles was investigated. Rate constants were determined for the hydrolyses in cetyltrimethylammonium bromide (ctab), the cationic surfactant, with 0.1111 N NaOH and in sodium 1-dodecanesulfonate, the anionic surfactant, with 0.09270 N HC1 at 50.01 + 0.11°C. The acid hydrolysis and the base hydrolysis of N-methyloctanobydroxamic acid followed the standard model for micellar catalysis.

Kinetics And Mechanism Of Acylation Of Amines With 2-Naphthoyl Azide, Abraham L. Faburada

Dissertations

The reaction of 2-naphthoyl azide with primary and secondary amines in protic and aprotic solvents follows second-order kinetics. The effect of increasing solvent polarity is shown to increase the rate of reaction. For amines of similar basicity, the rate of reaction decreases with increasing steric hindrance on the amine. The changes in free energy and entropy of activation for n-butylamine and cyclohexylamine are in accord with steric requirements of amines. For amines of similar steric hindrance, the rate of reaction increases with increasing amine basicity. The mechanism of addition-elimination involving the formation of a tetrahedral intermediate is consistent with the …

Micellarly Catalyzed Reaction Of Substituted Benzohydroxamic Acids, Nop Utrapiromsuk

Dissertations

The rate constants for hydrolysis of ten derivatives of benzohydroxamic acid, namely, p-H, p-CH(,3), m-CH(,3), p-CH(,3)CH(,2), p-OCH(,3), p-NO(,2), p-Cl, and m-Cl, in 0.160 and 0.158 M HCl at 67.9-68.2(DEGREES)C without and with sodium 1-dodecanesulfonate were determined. There is a good linear correlation between log k(,w) and the Hammett substituent constants, (sigma), for all para and meta derivatives where k(,w) is the rate constant in the bulk aqeous phase. In the presence of micelles all the compounds, except the meta-nitro derivative, followed the standard pseudophase model of micellar catalysis. However, correlations of log k(,m) or log K/N, where k(,m) is the …

Preparation And Properties Of Benzotropones And Benzohomotropones, Robert E. Suder

Dissertations

No abstract provided.

The Unexpected Preferential Formation Of 1-Alkyl-1-Phenyl-2–Propanones On Monoalkylation Of The 1-Phenyl-2-Propanone Dianion, Jack M. Hinkley

Masters Theses

No abstract provided.

The Effects Of Electron-Donating And Electron-Withdrawing Groups On The Alkylation Sites Of Para-Substituted Phenylacetones, Abraham L. Faburada

Masters Theses

The dianions of phenylacetone and its para-substituted derivatives were generated using potassium hydride and n-butyl lithium in tetrahydrofuran. Methyl, ethyl, and n-butyl iodides were used to alkylate the dianions. The results of alkulation indicated that C₁ is preferentially attacked by the less active ethyl and n-butyl iodides. The results further show that terminal alkylation is enhanced by electron-donating groups at the para-position of the phenyl ring. The results are rationalized in terms of the difference in electron density at C₁ and at C₃ in the dianion, on the basis of resonance theory. The regio-selectivity of alkylation as …

Determination Of The Rate Of Formation Of Hcn, Mitchell Hull

Honors Theses

Nitric oxide is a major air pollutant arising from fossil fuel combustion, yet the fuel contribution to its formulation is uncertain. Since, in combustion, fossil fuels undergo disintegration before oxidation takes place, the study of the pyrolsis of a model constituent of fossil fuels can shed light on NO formation. The rate of inert pyrolytic disappearance of pyridine and the rate of formation of the principal Nitrogen-containing pyrolytic product, HCN, was studied in an inert atmosphere. The rate constant for the formation of HCN and its temperature dependence were determined.

The Preparation And Study Of Some Bridged Tropones, Sultan T. Abu-Orabi

Masters Theses

No abstract provided.

Proximity Effects. Kinetics, Mechanisms And Reactivity Correlations For The Acidic And Alkaline Hydrolysis Of Ortho-Substituted-N-Methylbenzohydroxamic Acids, Irl E. Ward

Dissertations

No abstract provided.

Studies Toward The Total Synthesis Of A Colchicine Analog, Jacob Shya Tou

Masters Theses

No abstract provided.

Side-Chain Metalations Of Certain Dimethylpyridines By Means Of Organoalkali Metal Reagents, Stephen Bendzunas

Masters Theses

No abstract provided.

Unusual Alkylations Of The 1,1-Diphenyl-2-Propanone Dianion, Ruth E. Tenbrink

Masters Theses

No abstract provided.

The Synthesis And Study Of The Enolate Monoanion Of 2, 4-Di-P-Anisylbicyclo(3.2.1)Oct-6-En-3-One, Phillip D. Reynhout

Masters Theses

No abstract provided.

The Synthesis And Physical Properties Of Some 1-Methyl And 2-Methyl Bridged Cycloheptapyrazolones, Gary R. Larson

Masters Theses

No abstract provided.

The Effect Of Stabilizing Groups On The Extent Of Long-Range Π Electron Participation And The Effect Of The Negative Charge On The Chemical Shift Of Neighboring Protons In Carbanions, Atilla Tuncay

Dissertations

No abstract provided.

A Stereochemical Study Of Some 2,2'-Bridged Biphenyls, Alan J. Quarfoot

Dissertations

No abstract provided.

Asymmetric Induction In Grignard Reactions In A Chiral Solvent, John E. Davis

Dissertations

No abstract provided.

The Synthesis And Reactions Of Some Α, Β-Unsaturated Diazoketones, Virendra K. Sood

Masters Theses

No abstract provided.

The Effect Of Stereoelectronic Control And Long Range Interaction On The Stability Of Bicyclic Enolate Anions, Edwin M. Van Dam

Dissertations

No abstract provided.

The Formation And Study Of Certain Bicyclic Enolate Monoanions And Dianions, Ernest William Crowe

Masters Theses

No abstract provided.

The Wittig Reaction With Carbohydrates And The Addition Of Benzenesulfonyl Azides To Indoles, George R. Wellman

Dissertations

No abstract provided.

Part I. The Stereochemistry Of Carbanions Formed By Base Catalyzed Decomposition Of Azoacetates Part Ii. Anomalous Decarbonylation Of 4 –Substituted Carboxylic Acids With Thionyl Chloride, Tai-Shun Lin

Dissertations

Introduction

Although the stereochemical capabilities of carbonium ions have been extensively investigated, the stereochemical fate of carbanions has been subjected relatively little to systematic scrutiny. The fact that only a limited number of clean-cut sources of carbanions are available has added difficulty to such investigations.

The stereochemical capabilities of carbanions has been extensively and thoroughly examined in recent years by Cram and coworkers. However, the carbanion carbon developed in the reactions employed was bonded in every case to an unsaturated (usually aromatic) group. No fully aliphatic carbanion has been subjected to such a stereochemical study.

The reaction of lead tetraacetate …

The Synthesis And Photolysis Of Kreysiginone And The Syntheses And Antibacterial Activity Of 1-Vinyl-3,4-Dihydroisoquinoline Methiodides, Bruce L. Jensen

Dissertations

No abstract provided.

Preparation And Lead Tetraacetate Oxidation Of Aldehydic Hydrazones, Alan J. Quarfoot

Masters Theses

No abstract provided.

The Wittig Reaction Of Stabalized Phosphonium Ylids With Derivatives Of D-Ribose, George Robert Wellman

Masters Theses

No abstract provided.

Spectrophotometric Studies Of Complex Formation Of Alpha Aminohydroxamic Acids, Jing Shyong Chen

Masters Theses

No abstract provided.

Cerebrosides Of Human Aorta: Isolation And Fatty Acid Distribution, Eric Coles

Masters Theses

No abstract provided.

The Synthesis Of 3-Hydroxy-4-Imidazolidiones, Victor L. Rizzo

Masters Theses

No abstract provided.