Chemistry Commons^™

How Small Is Small?, Allison Marsh

Section 1: Introduction

No abstract provided.

Why Do We Collect?, Allison Marsh

Section 2: Imaging the Microscopic

No abstract provided.

Spotlight On Usc: A.C. Moore Herbarium, Allison Marsh

Section 2: Imaging the Microscopic

No abstract provided.

Imaging And Aesthetics, Allison Marsh

Section 2: Imaging the Microscopic

No abstract provided.

Observing The Minuscule, Allison Marsh

Section 2: Imaging the Microscopic

No abstract provided.

Listen, Allison Marsh

Section 3: Imaging the Fast Moving

No abstract provided.

Spotlight On Usc: Mechanical Engineering, Allison Marsh

Section 3: Imaging the Fast Moving

No abstract provided.

Photographic Evidence, Allison Marsh

Section 3: Imaging the Fast Moving

No abstract provided.

Influencing Art, Allison Marsh

Section 3: Imaging the Fast Moving

No abstract provided.

Department Of Chemistry News, Spring 2012, Illinois State University, Department Of Chemistry

Chem Letter

Newsletter of the Illinois State University Department of Chemistry

Investigation Of Polyurea-Crosslinked Silica Aerogels As A Neuronal Scaffold: A Pilot Study, Firouzeh Sabri, Judith A. Cole, M. Cody Scarbrough, Nicholas Leventis

Chemistry Faculty Research & Creative Works

Background: Polymer crosslinked aerogels are an attractive class of materials for future implant applications particularly as a biomaterial for the support of nerve growth. The low density and nano-porous structure of this material combined with large surface area, high mechanical strength, and tunable surface properties, make aerogels materials with a high potential in aiding repair of injuries of the peripheral nervous system. However, the interaction of neurons with aerogels remains to be investigated. Methodology: In this work the attachment and growth of neurons on clear polyurea crosslinked silica aerogels (PCSA) coated with: poly-L-lysine, basement membrane extract (BME), and laminin1 was …

Noncanonical Reactions Of Flavoenzymes, Pablo Sobrado

Chemistry Faculty Research & Creative Works

Enzymes containing flavin cofactors are predominantly involved in redox reactions in numerous cellular processes where the protein environment modulates the chemical reactivity of the flavin to either transfer one or two electrons. Some flavoenzymes catalyze reactions with no net redox change. In these reactions, the protein environment modulates the reactivity of the flavin to perform novel chemistries. Recent mechanistic and structural data supporting novel flavin functionalities in reactions catalyzed by chorismate synthase, type II isopentenyl diphosphate isomerase, UDP-galactopyranose mutase, and alkyl-dihydroxyacetone phosphate synthase are presented in this review. In these enzymes, the flavin plays either a direct role in acid/base …

Table Of Contents

Journal of the South Carolina Academy of Science

No abstract provided.

Scas Officers And Council Members 2011 - 2012

Journal of the South Carolina Academy of Science

No abstract provided.

Structural Properties Of Thermoresponsive Poly(N-Isopropylacrylamide)-Poly(Ethyleneglycol) Microgels, J. Clara-Rahola, A. Fernandez-Nieves, B. Sierra-Martin, A. B. South, L. Andrew Lyon, J. Kohlbrecher, A. F. Barbero

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

The application of RNA interference to treat disease is an important yet challenging concept in modern medicine. In particular, small interfering RNA (siRNA) have shown tremendous promise in the treatment of cancer. However, siRNA show poor pharmacological properties, which presents a major hurdle for effective disease treatment especially through intravenous delivery routes. In response to these shortcomings, a variety of nanoparticle carriers have emerged, which are designed to encapsulate, protect, and transport siRNA into diseased cells. To be effective as carrier vehicles, nanoparticles must overcome a series of biological hurdles throughout the course of delivery. As a result, one promising …

Vapor-Liquid Phase Equilibria Using Monte Carlo Wang-Landau Simulations, Tsvetan Aleksandrov

Theses and Dissertations

The experimental determination of the critical point of metals is inherently connected with difficulties of measuring large temperatures and pressures. On the other hand, that of straight alkane chains larger than ten carbon atoms and branched chains larger than eight atoms is burdensome due to decomposition of the molecules while in the vapor phase. Therefore molecular simulations stand as an appropriate alternative for determining the critical point and phase coexistence properties of these fluids. Most simulation methods that are apt for this task rely on particles insertion and deletion moves that can significantly complicate the simulation, since high density in …

Elucidation Of B-N And B-P Stretching Vibrations Using Raman Spectroscopy And Electronic Structure Calculations, Dana Nicole Reinemann

Honors Theses

Boron-nitrogen (B-N) and boron-phosphorus (B-P) dative bond stretching vibrational frequencies were studied using vibrational spectroscopic methods and electronic structure calculations. There has been a great controversy over the assignment of B-N dative bond vibrational frequencies for many years with a range of inconsistent assignments in the literature. The B-N dative bond stretching frequency in N-methyliminodiacetic acid (MIDA) esters was analyzed here using infrared, Raman, and surface enhanced Raman spectroscopic methods and compared to the results of electronic structure calculations employing the MP2 and M06-2X methods with a triple zeta basis set. The mode including the B-N stretching motion proved to …

Establishment Of Photo-Activated Localization Microscopy (Palm) For Imaging Signaling Complexes On The Surfaces Of Cells, Bradley E. Iverson

The Journal of Undergraduate Research

Photoactivated Localization Microscopy (PALM) permits visualization of single molecules inside cells at ~10 times the resolution of existing optical microscopes. The 10-50 nanometer resolution afforded by PALM is ideally suited to studying the organization of receptor signal transduction occurring on the surfaces of cells. Initial efforts presented here focused on cells expressing Fc receptor fused to photoactivatable green fluorescent protein (paGFP). A small fraction of the paGFP molecules were photoactivated using a 405 nm laser pulse, resulting in single molecule spots that could then be imaged using 488 nm laser excitation until they photobleached. Both lasers illuminated the sample through …

Anticancer Activity And Biophysical Reactivity Of Copper Complexes Of 2-(Benzo[D][1,3]Dioxol-5-Ylmethylene)-N-Alkylhydrazinecarbothioamides, Floyd A. Beckford, Jeffrey Thessing, Alyssa Stott, Alvin A. Holder, Oleg G. Poluektov, Liya Li, Navindra P. Seeram

Faculty Publications

A series of copper complexes were synthesized from benzo[d][1,3]dioxole-5-carbaldehyde (piperonal) thiosemicarbazones (RHpTSC where R = H, CH3, C2H5 or C6H5 (Ph)). The complexes show interesting variations in geometry depending on the thiosemicarbazone; a dinuclear complex [Cu(HpTSC)Cl]2, a mononuclear complex [Cu(RHpTSC)2Cl2] (R = CH3 or C2H5) and another mononuclear complex [Cu(PhHpTSC)(PhpTSC)Cl] was generated. The complexes bind in a moderately strong fashion to DNA with binding constants on the order of 10⁴ M^{− 1}. They are also strong binders of human serum albumin with binding constants near 10⁴ M^{− 1}. The complexes show good in vitro …

Synthesis And Flame Retardant Testing Of New Boronated And Phosphonated Aromatic Compounds, Vladimir Benin, Sravanthi Durganala, Alexander Morgan

Chemistry Faculty Publications

The present report describes the preparation and use of some dimethyl terephthalate derivatives in transition metal-catalyzed coupling reactions to produce new reactive flame retardants. Dimethyl iodoterephthalate and dimethyl 2,5-diiodoterephthalate were successfully employed in the preparation of phosphonic and boronic esters and acids. The latter were tested for heat release with a microcombustion calorimeter (ASTM D7309) to determine the potential for heat release reduction of these flame retardant molecules. The results showed that the addition of boronic or phosphonic acids greatly lowered the heat release, due to a condensed phase (char formation) mechanism. Adding ester groups to the boronic acids or …

Dynamics And Collective State Of Ordered Magnetic Nanoparticles In Mesoporous Systems, Jose M. Vargas, Abhishek Srivastava, Ezra Garza, Gabriel Caruntu, Amin Yourdkhani, Leonard Spinu

Chemistry Faculty Publications

In this paper we present a study of superparamagnetic and superspin glass states of magnetic nanoparticles confined in mesoporous templates. Characterization utilizes dynamic magnetization techniques, ac susceptibility, and ferromagnetic resonance, in addition to dc magnetization curves. In order to differentiate between the intrinsic and collective properties, we considered three magnetic nanoparticles systems with comparable size, shape, and crystallinity but with different intrinsic magnetocrystalline anisotropy. Further, confinement effects were studied by considering three different geometries of nanoparticles. The effect of the geometrical confinement and intrinsic anisotropy of the nanoparticles are discussed based on known theoretical predictions.

Synthesis And Piezoelectric Response Of Cubic And Spherical Linbo3 Nanocrystals, Debasish Mohanty, Girija S. Chaubey, Amin Yourdkhani, Shiva Adireddy, Gabriel Caruntu, John B. Wiley

Chemistry Faculty Publications

Methods have been developed for the shape-selective synthesis of ferroelectric LiNbO3 nanoparticles. Decomposition of the single-source precursor, LiNb(O-Et)6, in the absence of surfactants, can reproducibly lead to either cube- or sphere-like nanoparticles. X-Ray diffraction shows that the LiNbO3 nanoparticles are rhombohedral (R3c). Sample properties were examined by piezoresponse force microscopy (PFM) and Raman where both sets of nanoparticles exhibit ferroelectricity. The longitudinal piezoelectric coefficients, d33, varied with shape where the largest value was exhibited in the nanocubes (17 pm V21 for the cubes versus 12 pm V21 for spheres).

Magnetoelectric Effect In Ain/Cofe Bi-Layer Thin Film Composites, S Narendra Babu, Seong-Gi Min, Amin Yourdkhani, Gabriel Caruntu, Leszek M. Malkinski

Chemistry Faculty Publications

The present work is aimed at fabricating bi-layer aluminum nitride (AlN)/cobalt iron (CoFe) magnetoelectric (ME) thin films using reactive rf/dc magnetron sputtering. A systematic study on structural, morphological, piezoelectric, magnetic and magnetoelectric properties is undertaken. Except for AlN and CoFe, no other phases were detected with the layer thicknesses measured at160 and 130 nm, respectively. The rms roughness measured was around 2.096 nm for AlN and 1.806 nm for CoFe. The bi-layer thin film exhibited both good piezoelectricity and ferromagnetism, as well as ME effect. A 52% change observed in the piezoelectric signal, measured using magnetic field assisted piezoresponse force …

Dynamics And Collective State Of Ordered Magnetic Nanoparticles In Mesoporous Systems, Jose M. Vargas, Abhishek Srivastava, Ezra Garza, Amin Yourdkhani, Gabriel Caruntu, Leonard Spinu

Chemistry Faculty Publications

In this paper we present a study of superparamagnetic and superspin glass states of magnetic nanoparticles confined in mesoporous templates. Characterization utilizes dynamic magnetization techniques, ac susceptibility, and ferromagnetic resonance, in addition to dc magnetization curves. In order to differentiate between the intrinsic and collective properties, we considered three magnetic nanoparticles systems with comparable size, shape, and crystallinity but with different intrinsic magnetocrystalline anisotropy. Further, confinement effects were studied by considering three different geometries of nanoparticles. The effect of the geometrical confinement and intrinsic anisotropy of the nanoparticles are discussed based on known theoretical predictions.

Beta-Diketone And Beta-Ketoenamine Based Molecular Squares, Jackson Kiplagat Cherutoi

LSU Doctoral Dissertations

Abstract This dissertation focuses on synthesis of β-diketone and β-ketoenamine ligands for molecular polygons. Previous work with the bis(β-diketone) m-pbaH2 showed that it can be converted to a copper molecular square, Cu4(m-pba)4, but its use in host-guest reactions was limited by its low solubility in most organic solvents. Accordingly, in the present work, the m-pbhxH2 ligand, with pentyl chains replacing the methyl groups in the β-diketone moieties of m-pbaH2, was successfully prepared beginning with 6-dodecyne. This ligand reacts with Cu2+ to make the molecular square Cu4(m-pbhx)4, which is soluble in a wider range of solvents. Host-guest reactions of Cu4(m-pbhx)4 with …

Ionic Materials For Applications In Sensing And Optoelectronics, Sergio L. De Rooy

LSU Doctoral Dissertations

Organic salts consist of bulky anions and/or cations whose properties can be tailored for specific purposes. Ionic liquids (ILs) are (semi)organic salts with melting points below 100 ºC. They typically exhibit neglible vapor pressures, high thermal stability, wide liquidus range, and tunable solubility. Moreover specific functions can be built into their respective ions. The first part of the dissertation involves discussions of chiral ionic liquids with additional protic, magnetic, and magneto-luminescent properties, respectively. In addition to their enantioselective sensing capabilities, the ILs may find use in chiral separations and catalysis. The second part of the dissertation involves discussions of fluorescent …

Design, Synthesis, Characterization, And Application Of Peptides As Different Medical Treatment, Krystal Renee Fontenot

LSU Doctoral Dissertations

A peptide is defined, as a molecule that contains less than fifty amino acids; anything larger is a protein. Peptides are important molecules because they have diverse uses. Peptides were utilized in two ways: 1) Peptide bioconjugates containing a fluorescent porphyrin or phthalocyanine macrocycle were designed and investigated, with or without a PEG moiety for selective targeting of the epidermal growth factor receptor (EGFR). 2) Amyloid aggregating mitigating peptides (AAMPs) was synthesized and investigated containing polar amino acids, MiniPEGs, and/or ααAAs that have the ability to inhibit and disrupt Amyloid Beta (Aβ). The peptide bioconjugates containing a porphyrin or phthalocyanine …

Features For Non-Targeted Cross-Sample Analysis With Comprehensive Two-Dimensional Chromatography, Stephen E. Reichenbach, Xue Tian, Chiara Cordero, Qingping Tao

School of Computing: Faculty Publications

This review surveys different approaches for generating features from comprehensive two-dimensional chromatography for non-targeted cross-sample analysis. The goal of non-targeted cross-sample analysis is to discover relevant chemical characteristics (such as compositional similarities or differences) from multiple samples. In non-targeted analysis, the relevant characteristics are unknown, so individual features for all chemical constituents should be analyzed, not just those for targeted or selected analytes. Cross-sample analysis requires matching the corresponding features that characterize each constituent across multiple samples so that relevant characteristics or patterns can be recognized. Non-targeted, cross-sample analysis requires generating and matching all features across all samples. Applications of …

Quantitative Analysis Of Some Important Metals And Metalloids In Tobacco Products By Inductively Coupled Plasma-Mass Spectrometry (Icp-Ms), Syed Ghulam Musharraf, Muhammad Shoaib, Amna Jabbar Siddiqui, Muhammad Najam-Ul-Haq, Aftab Ahmed

Pharmacy Faculty Articles and Research

Background: Large scale usage of tobacco causes a lot of health troubles in human. Various formulations of tobacco are extensively used by the people particularly in developing world. Besides several toxic tobacco constituents some metals and metalloids are also believed to pose health risks. This paper describes inductively coupled plasma-mass spectrometric (ICP-MS) quantification of some important metals and metalloids in various brands of smoked, sniffed, dipped and chewed tobacco products.

Results: A microwave-assisted digestion method was used for sample preparation. The method was validated by analyzing a certified reference material. Percentage relative standard deviation (% R.S.D.) between recovered …

A New, Simple, Green And One-Pot Four-Component Synthesis Of Bare And Poly(Α, Γ, L-Glutamic Acid) Capped Silver Nanoparticles, Magdalena Stevanović, Igor Savanović, Vuk Uskoković, Srečo D. Škapin, Ines Bračko, Uroš Jovanović, Dragan Uskoković

Pharmacy Faculty Articles and Research

A simple and green chemical method has been developed to synthesize stable bare and capped silver nanoparticles based on the reduction of silver ions by glucose and capping by poly(α,γ,Lglutamic acid) (PGA). The use of ammonia during synthesis was avoided. PGA has had a dual role in the synthesis and was used as a capping agent to make the silver nanoparticle more biocompatible and to protect the nanoparticles from agglomerating in the liquid medium. The synthesized PGA-capped silver nanoparticles in the size range 5–45 nm were stable over long periods of time, without signs of precipitation. Morphological examination has shown …