Chemistry Commons^™

Multifunctional Ligands For Supramolecular Chemistry, James Kakoullis

LSU Master's Theses

Metal-organic frameworks (MOFs) are the primary focus of the Maverick research group, almost exclusively with the acac moeity. Before such MOFs can be attempted, multifunctional ligands of the appropriate geometry for the desired MOFs first must be synthesized. In this thesis, the synthesis and characterization of two new β-diketone ligands, specifically, Re(CO)₃Cl(PyacH)₂, 2.2, Pphac₃H₃, 1.23, and its oxide 3.6, are described. Also in this thesis, attempts to synthesize other new MOFs will be discussed. The MOF for which Re(CO)₃Cl(PyacH)₂, 2.2 was designed was Re(CO)₃ClCu(pyac)₂] …

Rate And Equilibrium Constants For Reactions Of Coordinated Cyclohexadienyl Cations, Martin Galvin

Doctoral

In this work, the nucleophilic reactions of ironcarbonyl coordinated cyclohexadienyl cations with water and hydroxide to produce the corresponding coordinated arene hydrate analogues was examined. These nucleophilic reactions are a key step in a synthetic route to convert arene cis-dihydrodiols to their trans-isomers via their tricarbonyliron coordinated complexes. The arene trans-dihydrodiols produced have significant potential to be used as chiral buildings blocks in synthetic chemistry and have the advantage that they are more stable then their cis-analogues The first cation studied was (п5-cyclohexadienyl)dicarbonyl-triphenylphosphineiron. An equilibrium constant, pKr, for formation of the coordinated arene hydrate (п4-exo-5-hydroxy-1,3-cyclohexadience)dicarbonyltriphenylphosphine-iron, from this coordinated cation was …

Landholder Information For The Safe Use And Management Of Strychnine For Wild Dog Traps, Renee Donovan, David Goodall

Biosecurity published reports

Farmnote 33/2003 - Guide to the safe use of strychnine for jawed traps is included.

Strychnine is a highly poisonous substance that is used in Western Australia for the control of Wild Dogs and Emus. Its use is restricted by law.

This manual outlines your roles and responsibilities for using and managing Strychnine for Wild Dog control. In particular, this manual outlines the essential information you need to know in regard to:

• The legislative requirements for Strychnine control in Western Australia
• The properties and mode of action of Strychnine « How to lodge an application to use Strychnine
• How to …

Landholder Information For The Safe Use And Management Of 1080, Renee Donovan, David Goodall

Biosecurity published reports

This manual outlines your roles and responsibilities for using and managing 1080. In particular this manual outlines the essential information you need to know in regard to:

• The legislative requirements for 1080 control in Western Australia
• The properties and mode of action of 1080
• How to lodge an application to lay 1080 baits How to safely store and transport 1080
• The procedures and notification required to carry out a baiting proposal
• Personal safety, identifying signs of poisoning & effecting appropriate first aid treatment
• Your responsibilities for notifying DAFWA and the Police of any accidents or incidents
• Methods for evaluating the …

Studies On The Preparation Of \Alpha,\Omega -Telechelic Polymers By The Combination Of Reverse Atom Transfer Radical Polymerization And Atom Transfer Radical Coupling Processes, Bi̇nnur Aydoğan, Yusuf Yağci

Turkish Journal of Chemistry

Monofunctional polystyrenes with cyano, carboxylic acid, and hydroxyl terminal groups were synthesized by reverse atom transfer radical polymerization (RATRP) using corresponding azo initiators in conjunction with copper and iron complexes. These functional polymers were further used in the atom transfer radical coupling (ATRC) reaction in the presence of Cu(I) and Cu(0) in order to obtain telechelic polystyrenes. In the iron-mediated system, while RATRP experiments gave satisfactory results, the corresponding ATRC process yielded polymers with low functionality. The copper-mediated system, however, gave contrary results. In the RATRP step, initiation efficiency was rather low and polymers with relatively higher polydispersity were obtained. …

Plasma-Initiated Polymerization Of (2-Methacryloyloxyethyl) Thrimethyl Ammonium Chloride, Yangang He, Gang Li, Jing Miao, Xueqing Yu, Fang Yang, Yingjun Cui, Fengxia Ren, Yang Chao

Turkish Journal of Chemistry

Plasma-initiated polymerization of (2-methacryloyloxyethyl) thrimethyl ammonium chloride (MTAC)) was studied. The effects of discharge time and discharge power on temperature in a tubular-type reactor chamber were accurately tested by on-line thermocouple, and the equation relating discharge time, discharge power and temperature in the tubular-type reactor chamber was derived. The results indicated that temperature played a very important role in controlling the solubility of Poly(MTAC) in water. For T \ge 130°, Poly(MTAC) was cross-linked, and the highest rate of absorbing water of Poly(MTAC) was 15 g · g^{-1}. For T < 130°, Poly(MTAC) was linear, and the highest intrinsic viscosity of Poly(MTAC) was 420.2 cm^3 · g^{-1}. The polymerization condition of linear Poly(MTAC) was optimized as follows: discharge time 60 s and discharge power 60 W.

Electrochemical Characteristics Of A 7-Ferrocenyl(Carbonyloxy)-1- Heptanethiol-Modified Gold Electrode, Mohammed Muzibur Rahman, Il Cheol Jeon

Turkish Journal of Chemistry

The electrochemical properties of 7-ferrocenyl(carbonyloxy)-1-heptanethiol [FcCO_2(CH_2)_7SH] were characterized by an electrochemical quartz crystal microbalance (EQCM). A gold surface was modified with FcCO_2(CH_2)_7SH by the self-assembly method. EQCM was used to investigate mass change during the redox reactions of FcCO_2(CH_2)_7SH monolayers on a modified gold electrode in solution containing K_3Fe(CN)_6 redox species. The FcCO_2(CH_2)_7SH monolayer on gold acts as a mediator for the electron transfer between a gold electrode and electroactive species Fe(CN)_6^{3-/4-} in solution. In both cases, electrochemical current responses were complicated because the observed currents were due to the redox of both the ferrocenyl group immobilized on gold and …

Electron Affinities, Solvation Energies And Redox Potentials Of Some Chalcones: Substituents` Effect And Correlation With Semi-Empirical Mo Energies, Abdur Rahman, Rumana Qureshi, Mehvish Kiran, Farzana Latif Ansari

Turkish Journal of Chemistry

Experimental and theoretical investigations were carried out on 2 sets of chalcones. Set 1 has an OH group on ring A and Set 2 does not, and both have different substituents on ring B at different positions. The experimental investigations comprised cyclic voltammetric (CV) studies to determine the reactivity in terms of redox potentials in DMF at room temperature (23 \pm 1 °C). Electrochemical parameters from cyclic voltammograms were used to evaluate the reversibility of electron transfer, standard reduction potentials, solvation energies, electron affinities, diffusion coefficients, critical scan rates and heterogeneous electron transfer rate constants. Heterogeneous electron transfer rate constants …

Synthesis And Spectral Characterisation Of Chloro Organotin(Iv) Di[3(2`-Hydroxyphenyl)-5-(4-Substituted Phenyl) Pyrazolinates], Umesh Nath Tripathi, Mohammad Safi Ahmad, Goriparthi Venubabu

Turkish Journal of Chemistry

Chloro organotin(IV) dipyrazolinates of the type RSnCl(C_{15}H_{12}N_2OX)_2 [where C_{15}H_{12}N_2OX = 3(2'-Hydroxyphenyl)-5(4-X-phenyl)pyrazoline {where X = H (a); CH_3 (b); OCH_3 (c); Cl (d) and R = Me, Pr^n and Ph] were synthesised by the reaction of RSnCl_3 with sodium salt of pyrazolines in 1:2 molar ratio, in anhydrous benzene. These newly synthesised derivatives were characterised by elemental analysis (C, H, N, Cl and Sn), molecular weight measurement and spectral [IR and multinuclear NMR (^1H, ^{13}C and ^{119}Sn)] studies. The bidentate behaviour of the pyrazoline ligands was confirmed by IR, ^1H and ^{13}C NMR spectral data. An octahedral structure around the tin(IV) …

New Aromatic Polyamide With Azo And Phosphine Oxide Groups In The Main Chain, Khalil Faghihi, Mohsen Hagibeygi

Turkish Journal of Chemistry

A new flame-retardant polyamide containing phosphine oxide and azobenzene moieties in the main chain was synthesized by the solution polycondensation reaction of 4,4`-azodibenzoic acid with bis(3-aminophenyl) phenyl phosphine oxide using thionyl chloride, N-methyl-2-pyrrolidone and pyridine. This new polymer was obtained in high yield (96%) and showed high inherent viscosity (0.55 dL/g) and was characterized by elemental analysis, FT-IR spectroscopy, thermal gravimetric analysis (TGA and DTG) and solubility test. Furthermore, another polyamide was prepared by solution polycondensation reaction of 4,4`-azodibenzoic acid with 1,4-phenylene diamine and its flame-retardant behavior was compared by the use of the LOI with the previous one.

Preparation And Characterization Of An Atenolol Selective Electrode Based On A Pvc Matrix Membrane, Nabil S. Nassory, Shabaz A. Maki, Mutaz A. Ali

Turkish Journal of Chemistry

Atenolol selective electrodes were prepared based on a complex atenolol-phosphotungstate as an active material using the plasticizers di-butyl phosphate (DBP), tri-butyl phosphate (TBP), o-nitro phenyl octyl ether (NPOE) and di-octyl phthalate (DOPH) in a PVC matrix membrane. The properties of the prepared electrodes were studied, namely slope, concentration range, detection limit, lifetime, pH effect and selectivity. The experimental results showed that the best electrode was based on DOPH as plasticizer, displaying a linear range from 1.00 x 10^{-4} M to 5.00 x 10^{-2} M with a Nernstian slope of 55.91 mV/decade and correlation coefficient of 0.9995. The detection limit was …

A Convenient Method For The Preparation Of 2-Aminobenzophenone Derivatives Under Ultrasonic Irradiation, Javad Safaei-Ghomi, Manouchehr Fadaeian, Alireza Hatami

Turkish Journal of Chemistry

A quick and convenient method for the preparation of 2-aminobenzophenone derivatives is described. This approach consists of the nucleophilic substitution reaction of nitrobenzenes by phenylacetonitrile under conventional and ultrasonic conditions followed by reduction of the produced 2,1-benzisoxazole to 2-aminobenzophenone. This 2-step reaction was studied by changing the reaction parameters (reaction temperature, ultrasound power, and reaction time). The results clearly demonstrated that using ultrasound irradiation results in a high yield within a short reaction time.

Examination Of Gold As A Metal Promoter Of Sulphated Zirconia In N-Heptane Isomerisation At Low Temperature, Ümi̇t Bi̇lge Demi̇rci̇, Francois Garin

Turkish Journal of Chemistry

Isomerisation of nC_7 over a sulphated zirconia (SZ)-based bifunctional catalyst was studied at 150 °C. Au, Ir, Pd and Pt were used as promoters of SZ. The first objective was the production of C_7 isomers with high octane numbers. PtSZ is the most suitable catalyst despite low conversions and a high proportion of methylhexanes instead of dimethylpentanes. The second objective was to assess Au as a promoter of SZ. Au shows slight hydrogenation abilities, displaying behaviour similar to that of Pd, but is inactive towards alkane activation. These promising but inadequate results suggested that Au could be used as the …

Synthesis Of 2-Acylamino, 2-Aroylamino And Ethoxycarbonyl Imino-1,3,4-Thiadiazoles As Antitumor Agents, Kemal Sancak, Yasemi̇n Ünver, Mustafa Er

Turkish Journal of Chemistry

2-Amino-1,3,4-thiadiazoles compounds (2a-e) were obtained from the reaction of thiosemi carbazide with 2-cyanomethoxyphenoxyacetonitriles (1). Mono acylamino, mono aroylamino and diethoxycarbonyl imino-1,3,4-thiadiazole compounds (3a-e, 4a-e, 5a-c) were synthesized via the reaction of 2-amino-1,3,4-thiadiazole compounds (2a-e) with acetyl chloride or acetic anhydride, benzoyl chloride or benzoic anhydride and ethyl chloroformate, respectively. The in vitro antitumor activities of some selected compounds were screened and compounds 2a, 2b, 2c, 3a, 3b, 3c, 5a, 5b and 5c were found to be active.

Chemoenzymatic Synthesis Of 2-Bromo-6-Hydroxy-3-Methoxy-2-Cyclohexen-1-One, Emi̇ne Özgül Karaaslan, Yasemi̇n Toka

Turkish Journal of Chemistry

A chemoenzymatic synthesis of 2-bromo-6-hydroxy-3-methoxy-2- cyclohexen-1-one starting from cyclohexane-1,3-dione is reported. Manganese(III) acetate-mediated acetoxylation followed by the enzyme-mediated hydrolysis of \alpha'-acetoxy enone affords hydroxy-enone 5 and acetoxy enone 4 with high enantiomeric excesses in good yields.

Iridoid Glucosides From Lamium Garganicum Subsp. Laevigatum, Tayfun Ersöz, Duygu Kaya, Funda Nuray Yalçin, Cavi̇t Kazaz, Erhan Palaska, Charlott H. Gotfredsen, Soren R. Jensen, İhsan Çaliş

Turkish Journal of Chemistry

Phytochemical investigations on the above-ground parts of Lamium garganicum subsp. laevigatum resulted in the isolation of 7 iridoid glucosides: shanzhiside methyl ester (1), barlerin (8-O-acetylshanzhiside methyl ester) (2), 6-O-syringyl-8-O-acetylshanzhiside methyl ester (3), 6\beta-hydroxyipolamiide (4), lamalbide (5), dehydropenstemoside (6), and sesamoside (7). The structure of the iridoids was elucidated by spectroscopic (UV, IR, 1D- and 2D-NMR, and ESI-MS) evidence.

Investigation Of Some 1,3-Diols For The Requirements Of Solvent Extraction Of Boron: 2,2,6-Trimethyl-1,3 Heptanediol As A Potential Boron Extractant, Bi̇lsen Tural, Servet Tural, Hali̇l Hoşgören

Turkish Journal of Chemistry

Eighteen 1,3-diols were synthesized and their structure and distribution ratio for the solvent extraction of boron were studied. Diols with a high distribution ratio (D_{B(OH)_3 > 10) were investigated for the requirements of solvent extraction of boron. Their extraction capacity, and solubility in aqueous phase and in organic diluents were investigated by comparison to 2-ethyl-1,3-hexanediol (EHD), which is widely used as a boron extractant. Among a series of 1,3 diols, 1-benzyl-2,2-dimethyl-1,3-propanediol (4a) and 2,2,6-trimethyl-1,3-heptanediol (3a) were found to have very low solubility in the aqueous phase compared to the others. IPD (3a) was found to have a high solubility in aliphatic …

Investigation Of The Voltammetric Characteristics Of Poly(1,4-Diaminobenzene) Film As A Dopamine-Selective Polymer Electrode, Gamze Erdoğdu, A. Ersi̇n Karagözler

Turkish Journal of Chemistry

Electrochemical polymerization of 1,4-diaminobenzene in the KCl aqueous electrolyte at a potential of 0.600 V versus Ag/AgCl produces adherent poly(1,4-diaminobenzene) film on a gold electrode. The electrochemical behavior of dopamine and ascorbic acid at the polymer electrode prepared in this manner was examined by cyclic and differential pulse voltammetry. Voltammetry studies showed that polymeric film with a thickness corresponding to a 7-mC charge exhibited selective permeation for dopamine while retaining ascorbic acid. All the polymerization parameters affecting the permselective characteristics were systematically investigated and the optimum values were determined. The results showed that a polymeric membrane, owing to its permselective …

Synthesis And Physico-Chemical And Spectroscopic Investigations Of Sodium Dihydrobis(1,2,3-Benzotriazolyl)Borate Ligand And Its Transition Metal Complexes, . Lutfullah, Ahmad Umar, Mohammed Muzibur Rahman, Mohammad Mansoob Khan, Yoon Bong Hahn

Turkish Journal of Chemistry

The title ligand, sodium dihydrobis(1,2,3-benzotriazolyl)borate, Na[H_2B(BTz)_2], was synthesized by refluxing 1 mole of sodium borohydride with 2 moles of 1,2,3- benzotriazole in toluene. The ligand shows ample reactivity towards Cr(III), Mn(II), Fe(III), Fe(II), Co(II), Ni(II), Cu(II), Zn(II), Cd(II) and Hg(II) metal ions and forms stable complexes. The ligand and its metal complexes were characterized by physico-chemical and spectroscopic techniques. All the complexes of divalent metal ions are tetrahedral except for Cu(II), which has been proposed to have a square-planar geometry. The complexes of Cr(III) and Fe(III) appear to have an octahedral geometry. The magnitude of molar conductance of 10^{-3} M …

Hydrothermal Synthesis, Characterization And Photocatalytic Activity Of Nanosized Tio_2 Based Catalysts For Rhodamine B Degradation, Funda Sayilkan, Meltem Asi̇ltürk, Şadi̇ye Şener, Sema Erdemoğlu, Murat Erdemoğlu, Hi̇kmet Sayilkan

Turkish Journal of Chemistry

Nanosize crystalline TiO_2 and SiO_2/TiO_2 mixed oxide particles as a photocatalyst for rhodamine B dye (RB) degradation in aqueous media were synthesized by a hydrothermal process at 200 °C. They were characterized using XRD, SEM, FT-IR, UV/VIS and BET analysis. The effects of silica content on the crystallinity and photocatalytic activity of TiO_2 were investigated. Photocatalytic activity of the nano-TiO_2 was compared with that of SiO_2/TiO_2 mixed oxides at the same conditions for degradation of RB, and mixed oxide catalysts showed more effective catalytic activity than the TiO_2. The results revealed that photodegradation of RB proceeds by pseudo-first-order reaction kinetics …

An Electrochemical Dna Biosensor For The Detection Of Dna Damage Caused By Radioactive Iodine And Technetium, Pinar Kara, Kağan Dağdevi̇ren, Mehmet Özsöz

Turkish Journal of Chemistry

A DNA damage process by radioactive iodine (I-131) and technetium (Tc-99m) is described. The procedure relies on a label-free electrochemical DNA biosensor. Fish sperm double stranded DNA was immobilized onto a carbon paste electrode (CPE) by electro deposition and the changes to the guanine oxidation signal were observed upon exposure to radioactive I-131 and Tc-99m by differential pulse voltammetry (DPV). The changes to the signal of guanine after exposure to therapeutic doses of Tc-99m and I-131 showed conformational changes in DNA molecules.

Mono-, Di- And Trinuclear Copper(Ii) Complexes Of A Schiff Base Ligand, 2-{(E)-[(6-{[(1e)-(2-Hydroxyphenyl)Methylene]Amino}Pyridin-2-Yl)Imino]-Methyl}Phenol, Nevi̇n Karaböcek, Serdar Karaböcek, Fatma Kormali

Turkish Journal of Chemistry

A Schiff base ligand, 2-{(E)-[(6-[(1E)-(2-hydroxyphenyl) methylene]amino}-pyridin-2-yl)imino]-methyl} phenol (H_2PySAL), was prepared by condensation of 2,6-diaminopyridine and salicylaldehide in EtOH. The Schiff base ligand was checked by elemental analyses, ^1H-NMR, ^{13}C-NMR, IR, UV/Vis, and mass spectral studies. Three new mono-, di-, and trinuclear copper(II) complexes of the Schiff base ligand, formula [Cu(H_2PySAL)]Cl_2, [Cu_2(PySAL) (Phen)]Cl_2, [Cu_3(PySAL)_2]Cl_2, were prepared and characterized by elemental analyses, magnetic moment, and IR, Uv/Vis, and mass spectral studies. The spectroscopic data of the complexes indicate that the copper(II) ions are coordinated by the oxygen atoms and nitrogen atoms (C=N) of the ligand. In the dinuclear complex, in which the …

Fft-Adsorptive Voltammetric Technique For Pico-Level Determination Of Tetracycline In Capsules At An Au Microelectrode In Flowing Solutions, Parviz Norouzi, Mohammad Reza Ganjali, Parandis Daneshgar

Turkish Journal of Chemistry

This study illustrates a novel method for fast monitoring of tetracycline in flow-injection systems. The fast Fourier transformation, along with continuous cyclic voltammetry (FFTCV) at a gold microelectrode in a flowing solution system, was used for the determination of tetracycline in its pharmaceutical formulation. The benefit of the developed technique is that it is simple, precise, accurate, time-saving, and economical compared to all of the previously reported methods. The effects of various parameters on the sensitivity of the method were investigated. Three considerable advantages are demonstrated by this method, which other methods do not possess. Firstly, there is no requirement …

Speciation Of Manganese Using A Pneumatic Flow Injection Analysis-Tandem Spectrometer System, Meissam Noroozifar, Mozhgan Khorasani-Motlagh, Reza Akbari

Turkish Journal of Chemistry

A pneumatic flow injection-tandem spectrometer system, without a delivery pump, was used for the speciation of manganese (Mn). In this system the suction force of the pneumatic nebulizer of a flame atomic absorption spectrometer (FAAS) was used for solution delivery through the manifold. Mn(VII) and total Mn (Mn(VII) and Mn(II)) concentrations were determined using a UV-Vis spectrometer and FAAS, respectively. The Mn(II) concentration was determined by the difference between the two. The calibration curves were linear up to 15.00 mg L^{-1} for Mn(VII) and total Mn, with a detection limit of 0.08 mg L^{-1} and 0.05 mg L^{-1} for Mn(VII) …

Synthesis Of Some New 1-Acylthiosemicarbazides And 1,2,4-Triazol-5-Thiones, And Their Analgesic And Anti-Inflammatory Activities, Yasemi̇n Dündar, Bi̇lge Çakir, Esra Küpeli̇, M. Fethi̇ Şahi̇n, Ni̇ngur Noyanalpan

Turkish Journal of Chemistry

We synthesized new 1-[3-(2-oxobenzothiazolin-3-yl)propanoyl]-4- substituted-thiosemicarbazides and their corresponding cyclized 3-[2-(2-oxobenzothiazoline-3-yl)ethyl]-4-substituted-1,2,4-triazol-5-thione ana-logs in which position 4 of the triazole ring was substituted by cyclohexyl, methyl, allyl, phenyl, p-methylphenyl, p-methoxyphenyl, p-chlorophenyl, p-nitrophenyl, benzyl, and phenylethyl to screen their analgesic and anti-inflammatory activities as well as gastric ulceration potential in test animals. None of the compounds, except 5a, 5e, and 5h, caused gastric lesions or bleeding. Compound 5g was found to have higher analgesic and anti-inflammatory activity among the synthesized compounds.

Synthesis Of Some Novel 3,5-Diaryl-1,2,4-Triazole Derivatives And Investigation Of Their Antimicrobial Activities, Mevlut Serdar, Nurhan Gümrükçüoğlu, Şengül Alpay Karaoğlu, Nesli̇han Demi̇rbaş

Turkish Journal of Chemistry

A series of acylhydrazones (2a-d) was synthesized from the reactions of iminoester hydrochlorides (1a-e) with acyl hydrazines. 2,5-Dialkyl 1,3,4-oxadiazoles (3a-d) were obtained in the same reaction media. The treatment of acylhydrazones with hydrazine hydrate afforded 4-amino-3,5-dialkyl-1,2,4-triazoles (4a-c). The acetylation of 4-amino-3-(4-hydroxyphenyl)-5-phenyl-4H-1,2,4-triazole (4a) produced 4-amino-5-(4-acetoxyphenyl)-3-phenyl-4H-1,2,4-triazole (9), while the acetylation of 4-amino-3-(4-tolyl)-5-phenyl-4H-1,2,4-triazole (4b) gave 4-acetylamino-3-phenyl-5-(4-tolyl)-4H-1,2,4-triazole (10). The treatment of compound 4b with various aromatic aldehydes or acetophenone and 4-nitroacetophenone resulted in the formation of 4-arylidenamino-3,5-dialkyl-4H-1,2,4-triazoles (5a-e and 7a,b). Sodium borohydride reduction of 4-arylidenamino derivatives of 1,2,4-triazoles afforded 4-alkylamino-3,5-dialkyl-4H-1,2,4-triazoles (6a-e and 8a,b). All newly synthesized compounds were screened for their antimicrobial and antifungal …

Synthesis And Antimicrobial Activities Of Some New 1,2,4-Triazole Derivatives, Nurhan Gümrükçüoğlu, Mevlut Serdar, Eli̇f Çeli̇k, Ali̇ Sevi̇m, Nesli̇han Demi̇rbaş

Turkish Journal of Chemistry

A series of acylhydrazones (2a-f) were synthesized by the condensation of iminoester hydrochlorides (1a-f) with acyl hydrazines. 2,5-Dialkyl 1,3,4-oxadiazoles (3a,c,e) were obtained in the same reaction media. The treatment of acylhydrazones with hydrazine hydrate afforded 4-amino-3,5-dialkyl-1,2,4-triazoles (4a-c). The acetylation of 4-amino-3,5-dialkyl-1,2,4-triazoles produced N-[3,5-dialkyl-4H-1,2,4-triazol-4-yl] acetamides (5-7). The treatment of compounds 4a and 4c with various aromatic aldehydes resulted in the formation of 4-arylidenamino-3,5-dialkyl-1,2,4-triazoles (8a,d, e, and 10a-e). Sodium borohydride reduction of 4-arylidenamino derivatives afforded 4-alkylamino-3,5-dialkyl-1,2,4-triazoles (9a,d, e, and 11a-e). Compounds 4b, 4c, 7, 8d, and 11c showed good antifungal activity only against yeast-like fungi, while compounds 3e, 6, 8e, and 9e …

Synthesis, Spectroscopic Investigation, Crystal Structure, And Biological Screening, Including Antitumor Activity, Of Organotin(Iv) Derivatives Of Piperonylic Acid, Muhammad Hanif, Mukhtiar Hussain, Saqib Ali, Moazzam H. Bhatti, Muhammad Sheeraz Ahmed, Bushra Mirza, Helen S. Evans

Turkish Journal of Chemistry

We prepared 8 new organotin compounds with the general formulae [R_3SnL], where R = Me (1), Bu (2), Ph (3), and Cy (4) and [R_2SnL_2], where R = Me (5), Et (6), Bu (7), Oct (8), and L = piperonylic acid, and characterized them by elemental analyses, IR spectra, and multinuclear NMR (^1H, ^{13}C, and ^{119}Sn). The structure of 5 was confirmed by single crystal X-ray crystallography. The geometry around the tin atom was compared in both solution and solid state. Crystals of 5 are monoclinic with the space group P2_1/c. The tin geometry is skew trapezoidal bipyramidal, with 2 …

Synthesis, Characterization, And Biocidal Studies Of The Newly Synthesized Di- And Triorganotin(Iv) Complexes With N-Butylhydrogen Phthalate, Sadiq-Ur Rehman, Saqib Ali, Saira Shahzadi, Abdul Malik, Ejaz Ahmed

Turkish Journal of Chemistry

Di-(1, 3, 8) and triorganotin(IV) complexes (2, 5, 7) with the general formula R_nSnL_{4-n}, where R = Me, Et, n-Bu, n-Oct, Ph, and Bz, and L = the n-C_4H_9OCOC_6H_4COO^- monoanionic ligand have been synthesized by the reaction of the silver salt of the n-butylhydrogen phthalate with di- and triorganotin chloride in dry chloroform. However, di-n-butyl- and di-n-octyltin(IV) derivatives (4 and 6, respectively) were synthesized by the reaction of the corresponding organotin(IV) oxide with n-butylhydrogen phthalate in dry toluene. All the synthesized complexes were characterized by elemental analysis, FT-IR, multinuclear (^1H, ^{13}C, ^{119}Sn) NMR, and mass spectrometric techniques to assess the …

Selenium And Trace Element Distribution In Astragalus Plants: Developing A Differential Pulse Polarographic Method For Their Determination, Güler Somer, A. Cengi̇z Çalişkan

Turkish Journal of Chemistry

Astragalus plants have a wide range of applications in pharmaceuticals (gum tragacanth), as thickening agents in foods, and may have applications in controlling cancer cells. They are used as feed for animals and they are indicator plants for selenium. Because of their use in health-related areas it is very important to determine their selenium and trace element content with high accuracy. A new differential pulse polarographic method was established for trace element determination (10 elements) and their distribution in these plants. The Astragalus plants investigated in this work are Astragalus microcephalus and Astragalus lusitanicus, which grow almost everywhere. Their roots, …