Chemistry Commons^™

Metathesis Key In Production Of Pharmaceuticals, Plastics, Aldemaro Romero Jr., Michael J. Panigot

Publications and Research

No abstract provided.

The Effect Of Cu-Doping On The Magnetic And Transport Properties Of La₀.₇Sr₀.₃Mno₃, M. S. Kim, Jinbo Yang, Qingsheng Cai, X.-D. Zhou, William B. Yelon, Paul Ernest Parris, William Joseph James

Physics Faculty Research & Creative Works

The effects of Cu-doping on the structural, magnetic, and transport properties of La0.7Sr0.3Mn1xCuxO3 (0<=x<=0.20) have been studied using neutron diffraction, magnetization, and magnetoresistance (MR) measurements. All samples show the rhombohedral structure with the R[overline 3]c space-group from 10 K to room temperature (RT). Neutron diffraction data suggest that some of the Cu ions have a Cu3+ state in these compounds. The substitution of Mn by Cu affects the MnO bond length and Mn-O-Mn bond angle resulting from the minimization of the distortion of the MnO6 octahedron. Resistivity measurements show that a metal to insulator transition occurs for the x>=0.15 samples. The x=0.15 sample shows the highest MR([approximate]80%), which might result from the co-existence of Cu3-Cu2+ and the dilution effect of Cu-doping on the double exchange interaction

Dissolution, Reactor, And Environmental Behavior Of Zro2-Mgo Inert Fuel Matrix, Kenneth Czerwinski

Fuels Campaign (TRP)

This project examines inert fuels containing ZrO₂ and MgO as the inert matrix, with the relative amount of MgO varied from 30% to 70% in ZrO₂. Reactor physics calculations are used to examine suitable quantities of burnable poisons from the candidate elements Gd, Er, or Hf with reactor grade Pu providing the fissile component, with up to 10% of ²³⁹Pu. Ceramics are synthesized and characterized based on the reactor physics results. The solubility of the fuel ceramics, in reactor conditions, reprocessing conditions, and repository conditions, are investigated in a manner to provide thermodynamic data necessary for …

Assessment Of Rarity Of The Blackmouth Shiner Notropis Melanostomus (Cyprinidae) Based On Museum And Recent Survey Data, Martin O'Connell

Earth and Environmental Sciences Faculty Publications

Accurate knowledge of an organism's distribution is necessary for conserving species with small or isolated populations. A perceived rarity may only reflect inadequate sampling effort and suggest the need for more research. We used a recently developed method to evaluate the distribution of a rare fish species, the blackmouth shiner Notropis melanostomus Bortone 1989 (Cyprinidae), which occurs in disjunct populations in Mississippi and Florida. Until 1995, N. melanostomus had been collected from only three localities in Mississippi, but in 1995, eight new localities were discovered. We analyzed museum records of fish collections from Mississippi, Florida, and Alabama to compare sampling …

Assessment And In Vitro Repair Of Damaged Dna Templates From Forensic Stains, Ashley Hall

Electronic Theses and Dissertations

DNA extracted from biological stains is often intractable to analysis. This may due to a number of factors including a low copy number (LCN) of starting molecules, the presence of soluble inhibitors or damaged DNA templates. Remedies may be available to the forensic scientist to deal with LCN templates and soluble inhibitors but none presently exist for damaged DNA. In fact, only recently has the biochemical nature, the extent of DNA damage in physiological stains and the point at which the damage inflicted upon a particular sample precludes the ability to obtain a genetic profile for purposes of identification been …

Exploring Marine Biotoxins Using Analytical Techniques Based On Mass Spectrometry, Mónica Fernández Amandi

Theses

The impact of phycotoxins on human and animal health is of important concern for worldwide authorities and the scientific community. Domoic acid (DA) is a neurotoxin produced by phytoplankton {Pseudonitzchia spp.). It enters the food chain through the consumption of shellfish that feed on toxic diatoms. DA has been responsible for several outbreaks affecting humans and animals all around the world. Yessotoxin (YTX) is produced by dinoflagellate species {Protoceratiuni reticulatum) which are globally distributed. Its toxicity is low when ingested orally. However, the co-extraction of YTX with diarrhetic shellfish poisoning (DSP) toxins, derives false positives when the mouse bioassay is …

Elucidation Of The Mass Spectral Fragmentation Pathways Of Cyclic Hepatopeptides Microcystins, Paloma Muniz Ortea

Theses

The most frequently found cyanobacterial toxins in blooms from fresh and brackish waters are the cyclic peptide microcystins (MCs) and nodularin family. These toxins cause fatal poisonings of agricultural livestock, wild animals, birds and fish on a worldwide basis. The involvement of these toxins in human health problems has also been inferred in several countries and their presence in drinking water sources is of interest to the drinking water industry.

One of the biggest problems in the analysis of MCs is the lack of commercially available standards to be used for the identification and characterisation of these cyanobacterial toxins. One …

Effect Of Phosphoric Acid Anion Structure On The Corrosion Inhibition Of Steel By Polyaniline, Yasir Idlibi, Thomas P. Schuman, James O. Stoffer

Chemistry Faculty Research & Creative Works

Conductive polymers such as polyaniline (PAni) have been examined as candidates for replacing the existing chromate systems. Protonation of emeraldine base creates polarons and bipolarons, single and paired radical cations, respectively, of higher bond energy levels within the molecular orbital band gap.' For a conductive coating, considerable delocalization of corrosion charge and potential may be obtained along or between the polymer chains, because of high electron mobility. Current corrosion systems based on polyaniline typically rely on sulfuric or sulfonic acids as a dopant material, since synthetic techniques utilize persulfates as the oxidant of choice. In our experience, sulfonic/sulfuric acid systems …

An Hmm-Based Framework For Video Semantic Analysis, Gu Xu, Yu-Fei Ma, Hong-Jiang Zhang, Shiqiang Yang

Chemistry Faculty Research & Creative Works

Video semantic analysis is essential in video indexing and structuring. However, due to the lack of robust and generic algorithms, most of the existing works on semantic analysis are limited to specific domains. In this paper, we present a novel hidden Markove model (HMM)-based framework as a general solution to video semantic analysis. In the proposed framework, semantics in different granularities are mapped to a hierarchical model space, which is composed of detectors and connectors. In this manner, our model decomposes a complex analysis problem into simpler subproblems during the training process and automatically integrates those subproblems for recognition. The …

Effect Of Plasticizer On Pvac-D3 Dynamics Using 2h Solid-State Nmr, Rakesh R. Nambiar, Frank D. Blum

Chemistry Faculty Research & Creative Works

Poly(vinyl acetate) (PVAc) is an important polymer for use in many applications due to its various bulk and surface characteristics. The structure of poly(vinyl acetate) results in a relatively low glass transition temperature (Tg) and makes it important for processing and applications such as paints, adhesives, thin films and surface coatings. Poly(vinyl acetate) can also be easily plasticized, widening its range of applications. The term "plasticizer" refers to a species that will decrease Tg of a polymer.1 Polymer-plasticizer systems have been studied for years and continue to be of current interest. The effects of polymer-plasticizer interactions2 and plasticizer structure3 on …

Estimation Of Bound Carbonyls In Pmma-R-Ps Copolymers Adsorbed On Silica, Pavan K. Challa, Bing Zhang, Frank D. Blum

Chemistry Faculty Research & Creative Works

The adsorption of random copolymers on solid surfaces is essential for developing good properties in composite materials. A good control and understanding of interfaces allows tuning of the properties of the individual components. Interfacial polymers are important in many industrial applications such as photoresists, protective coatings, metal insulator and semi-conductor insulator junctions, metal-filled polymer composites and polymer-lined metal containers for protective food packaging. The effect of the drying process,1 configuration and tacticity,2 molecular mass, density of surface hydroxyls,3 and adsorbed amounts4 have already been studied for interfacial polymers. The thermal characterization for polystyrene,5 PMMA11 and PMMA-r- PS6 copolymers adsorbed on …

Magnetic Properties Of (Γ-Fe₂O₃)₈₀Ag₂₀ Nanocomposites Prepared In Reverse Micelles, Joan A. Wiemann, Jianbiao Dai, Jinke Tang, Gary J. Long, Leonard Spinu

Chemistry Faculty Research & Creative Works

The magnetic properties of nanoparticles of gamma-Fe2O3 prepared by reverse micelles have been studied by dc magnetization, transverse ac susceptibility, and Mössbauer spectroscopy. The nanoparticles of gamma-Fe2O3 in the nanocomposite (gamma-Fe2O3)80Ag20 exhibit superparamagnetic behavior. The blocking temperatures determined by the three methods indicate the superparamagnetic nature of (gamma-Fe2O3)80Ag20 above 70-80 K and show correlation with measuring time. The average particle diameter obtained by transmission electron microscopy of the gamma-Fe2O3 particles is ~10 nm and that of the Ag particles is ~20 nm. The average particle size determined from the magnetic analyses for the gamma-Fe2O3 particles is ~12 nm. Mössbauer spectra …

Segmental Dynamics In Poly(Methyl Acrylate)-D3 On Strongly And Weakly Adsorbing Silica Surfaces, Burak Metin, Frank D. Blum

Chemistry Faculty Research & Creative Works

The segmental dynamics of a polymer on a solid surface appears to be significantly different than that in bulk. The strength of the interaction between polymer segments and a solid surface is likely to be an important factor affecting the segmental mobility of the polymers. Studies of polymers on a weakly adsorbing surface would provide additional understanding of their motional characteristics on surfaces. In a recent NMR study by Rivillon et al., chain dynamics was seen to be different for samples, even when there was no specific interaction with the surface. Peanasky et al. have found a restricted segmental dynamics …

Synthesis And Electropolymerization Of 2-(3-Thienylethyl)-3-Thiopheneacetate, Nicholas Leventis, Chariklia Sotiriou-Leventis, Sudhir Mulik, Amala Dass

Chemistry Faculty Research & Creative Works

Conducting polymers offer great promise in the development of electronic devices, displays and sensors. In that regard, biomolecules can be attached to these polymers via functional groups, but the presence of such groups oftentimes hinders polymerization.1-3 One strategy is to polymerize a functionalized monomer precursor of a conducting polymer, followed by reaction of the dangling functional groups of the polymer with appropriately functionalized labels. An attractive functionalized thiophene for that purpose is 3-thienylethanol. Unfortunately, however, this monomer is not polymerizable.1,2 Thus, 3-thienylethanol has been esterified, followed by co-polymerization with 3-methylthiophene (3-MT), and subsequent hydrolysis of the ester to the free …

Synthesis And Nmr-Characterization Of Three Quinamide-Based Disaccharide Mimetics With Unusual Cyclohexane Twist-Conformation, Thuy Trang M. Nguyen, Paul H. Gross, Andreas H. Franz

College of the Pacific Faculty Articles

The synthesis of amide-linked disaccharide mimetics has been explored starting with carbohydrate-based amines and a protected quinic acid lactone. Benzyl-2-amino-4,6-Obenzylidene-2-deoxy-α/β-D-glucopyranose (12) and D-glucamine (14) were successfully coupled to give the corresponding quinamides (13 and 15), while the quinoylation of Oacetylated L-fucopyranosyl methylamine (7) failed. The latter was prepared from per-O-acetylL-fucopyranose via the improved multigram scale synthesis of the corresponding per-O-acetylL-fucopyranosyl cyanide (3). Compound 3 was subsequently hydrogenated to yield a mixture of compound 7 and the per-O-acetylated bis-(fucopyranosylmethyl) amine (5). The vicinal coupling constants in the NMR spectra of all quinamide products revealed considerable flexibility of the cyclohexane ring in …

Electronic To Vibrational Energy Transfer From Cl* (3 2P1/2) To N2O(Ν1): Failure Of A Simple Kinetic Mechanism, Brian Brumfield

Browse all Theses and Dissertations

Experimental kinetic studies were carried out examining the electronic to vibrational (E-V) energy transfer from spin-orbit excited Cl*(3 ²P_1/2 , 882 cm^-1) to N₂O(ν₁) (symmetric stretch 1285 cm^-1). All studies were carried out in the gas phase at room temperature (298 ± 2 K). Cl* was generated by pulsed laser photolysis of ICl at 532 nm in the presence of various mixtures of N₂O, ICl,Ar, and SO₂. Time-resolved IR signals of N₂O(ν₁) fluorescence at 7.8 μm were analyzed to obtain rate coefficients …

Bismuth Triflate Catalyzed Friedel-Crafts Acylations Of Sydnones, Jennifer Ann Fisher

Browse all Theses and Dissertations

In the present work, suitably functionalized arylsydnones were used to synthesize a variety of 4-acylsydnones and diacyl sydnones, both as potential precursors to novel sydnoquinolines.The approach to the diacyl species is based on the discovery that activated sydnonesbrominate in both the 4 position of the sydnone ring and on the phenyl ring. Thus, it seemed likely that Friedel-Crafts reactions on an activated sydnone would give diacylated species for McMurray coupling to sydnoquinolines. Friedel-Crafts acylations on the 4 position of the sydnone ring have been achieved in high yields using 4 equivalents of various alkyl anhydrides, 25 mol % of bismuth …

Mechanism Of Ion-Pair Chromatography And Chromatographic Behavior Of Liophilic Ions, Irina Leonidovna Kazakevich

Seton Hall University Dissertations and Theses (ETDs)

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Reaction Of Organosilicon Hydrides With Inorganic Surfaces: An Example Of Surface Catalyzed Self-Assembly And Water Porosimetry: A New Technique To Characterize Hydrophobic Porous Surfaces And Wetting In Nano-Confinement, Roy Helmy

Seton Hall University Dissertations and Theses (ETDs)

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Solid Phase Microextraction And Stir Bar Sorptive Extraction Coupled To Ion Mobility Spectrometry, John K. Lokhnauth

Seton Hall University Dissertations and Theses (ETDs)

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Synthesis Of Novel Porphyrazines And Binding Studies To Dna Quadruplexes, Carlos Ramirez

Seton Hall University Dissertations and Theses (ETDs)

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Analytical Tools For Studying Phosphorus And Nitrogen Lake Nutrient Dynamics And Their Application To The Field, Ivan Mihajlov

Honors Theses

In order to evaluate the causes and conditions that lead to cyanobacteria blooms in northern temperate lakes, studies of nutrients such as total phosphorus, total nitrogen, phosphate, and nitrate are necessary. Sensitive, environmentally friendly and cost-effective techniques were developed to detect ppb-level nitrates and phosphates in the lake water. Phosphate was analyzed by luminol chemiluminescence, while the quantification of nitrate was performed by capillary electrophoresis (CE) using indirect UV detection, with a background electrolyte consisting of pyromellitic acid, hexamethonium hydroxide and triethanolamine. Sample injection methods for the CE were optimized for the analysis in Belgrade Lakes, Maine. Vertical profiles of …

Investigation Of Iron (Iii) Desferrioxamine B Oxalate Ligand Exchange By Uv-Vis Spectroscopy: The Next Step In Developing A Quantitative Analytical Method For Measuring Bioavailable Iron In Marine Ecosystems, Ken L. Pitter

Honors Theses

To date there are no analytical techniques designed to exclusively measure bioavailable iron in marine environments. The goal of this research is to develop such a technique by isolating the bioavailable iron using the terrestrial siderophore desferrioxamine B (DFB). This project contained many challenging aspects, but the specific goal of this study was to develop a robust analytical technique for quantification of Fe(III)-DFB complexes at nanomolar concentrations. Past work showed that oxalate (Ox) promotes photodissociation of Fe(III)-DFB to Fe(Il), and we are specifically interested in the mechanism of this process. A model was developed using known thermodynamic constants for Fe(III)-DFB …

Photochemical Generation Of 2-Methoxy-2methylpropylidene And Its Rearrangement Pathways, Stanislav Presolski

Honors Theses

2-methoxy-2-methylpropylidene was photochemically generated from a non-nitrogenous precursor, 1a,9b-Dihydro-IH-cyclopropa[1]phenanthrene-l-etbane 2-methoxy-2-methyl, available in two steps from phenanthrene. Two competing rearrangement pathways were observed for the p-methoxy carbene, 1,2-methyl shift and C-H insertion, which had varying weights depending on the solvent used. Nevertheless, the C-H insertion was always predominant, contrary to the current understanding of B-substituted carbenes, which apparently needs revision. An attempt was also made to measure by LFP the rate constant of rearrangement and lifetime of the stabilized l-chloro-2-methoxy-2-metbylpropylidene.

The Reno Aerosol Optics Study: An Evaluation Of Aerosol Absorption Measurement Methods, Patrick J. Sheridan, W. Patrick Arnott, John A. Ogren, Elisabeth Andrews, Dean B. Atkinson, David S. Covert, Hans Moosmüller, Andreas Petzold, Beat Schmid, Anthony W. Strawa, Ravi Varma, Aki Virkkula

Chemistry Faculty Publications and Presentations

The Reno Aerosol Optics Study (RAOS) was designed and conducted to compare the performance of many existing and new instruments for the in situ measurement of aerosol optical properties with a focus on the determination of aerosol light absorption. For this study, simple test aerosols of black and white particles were generated and combined in external mixtures under low relative humidity conditions and delivered to each measurement system. The aerosol mixing and delivery system was constantly monitored using particle counters and nephelometers to ensure that the same aerosol number concentration and amount reached the different instruments. The aerosol light-scattering measurements …

Nonaqueous Platination For Synthesis Of Platinated 7 Alpha-Substituted Estradiol, Sarah A. Mazzella

Masters Theses

Cisplatin, carboplatin, and oxaliplatin are used clinically for treating some cancers, but are they are not the preferred treatment for breast cancer. The usefulness of these platinum-containing drugs is limited by poor concentration of the active platinum moiety within the tumor before dose-limiting side effects are reached. One way to selectively concentrate a platinum antitumor compound in breast cancer cells is to conjugate the platinum moiety via a malonate linkage to an estrogen which selectively binds to the estrogen receptor (ER) protein. The major obstacle to linking a lipophilic estrogen to a diamino-platinum compound is the lack of solubility of …

The Application Of 31p And 1h Nmr Spectroscopy To The Study Of Freeze Tolerance And Freeze Avoidance In Biological Systems, Nicholas C. Wright

Masters Theses

31P NMR spectroscopy was used to study freeze tolerance of the wood frog, R. sylvatica. Spectra were obtained of living whole body samples and isolated thigh muscle tissue. These results were compared to R. pipiens which is freeze sensitive. R. sylvatica was found to have significantly higher levels of glucose-6-phosphate and several phosphodiesters. Both seasonal and environmental stresses were studied to determine the effect of freezing conditions on the phosphorus compounds present in R. sylvatica. The results show that R. sylvatica is capable of tolerating stresses that are associated with freezing without any drastic changes in the levels of metabolic …

Structural Study Of Disease Related Proteins, Ayse Sinem Ozyurt

Electronic Theses and Dissertations

The availability of complete sequences for the genomes of many organisms changes the researcher's attention from genome sequencing to finding the function of gene products, the proteins. The three dimensional (3D) structure of a protein is helpful to understand its function, because tertiary structure is more conserved in evolution than sequence. The 3D structures can be found quickly by using high-throughput (HT) methods for protein expression, purification, characterization and structure determination. This process is very challenging in every step. Therefore we selected nearly 200 cancer related proteins as targets to see the difficulties in trying to determine the web predicted …

The Use And Development Of Laser Microdissection To Separate Spermatozoa From Epithelial Cells For Str Analysis, Christine Sanders

Electronic Theses and Dissertations

Short Tandem Repeat (STR) analysis has become a valuable tool in identifying the source of biological stains, particularly from the investigation of sexual assault crimes. Difficulties in analysis arise primarily in the interpretation of mixed genotypes when cell separation of the sexual assailant's sperm from the victim's cells is incomplete. The forensic community continues to seek improvements in cell separation methods from mixtures for DNA typing. This report describes the use of laser microdissection (LMD) for the separation of pure populations of spermatozoa from two-donor cell mixtures. In this study, cell separation was demonstrated by microscopic identification of histologically stained …

Synthesis Of Cyclopropanes Via Organoiron Methodology: Preparation Of The C9–C16 Alkenylcyclopropane Segment Of Ambruticin, Julie Lukesh, William A. Donaldson

Chemistry Faculty Research and Publications

A synthesis of the C9–C16 segment of ambruticin is described which relies on organoiron methodology to establish the 1,2,3-trisubstituted cyclopropane ring.