Applied Mathematics Commons^™

Mathematical Modeling Of Nonlinear Problem Biological Population In Not Divergent Form With Absorption, And Variable Density, Maftuha Sayfullayeva

Acta of Turin Polytechnic University in Tashkent

В работе установлены критические и двойные критические случаи, обусловленные представлением двойного нелинейного параболического уравнения с переменной плотностью с поглощением в "радиально-симметричной" форме.Такое представление исходного уравнения дало возможность легко построить решения типа Зельдовоч-Баренбатт-Паттл для критических случаев в виде функций сравнения.

Mathematical Modeling Of Diabetic Foot Ulcers Using Optimal Design And Mixed-Modeling Techniques, Michael Belcher

Mahurin Honors College Capstone Experience/Thesis Projects

A mathematical model for the healing response of diabetic foot ulcers was developed using averaged data (Krishna et al., 2015). The model contains four major factors in the healing of wounds using four separate differential equations with 12 parameters. The four differential equations describe the interactions between matrix metalloproteinases (MMP-1), tissue inhibitors of matrix metalloproteinases (TIMP-1), the extracellular matrix (ECM) of the skin, and the fibroblasts, which produce these proteins. Recently, our research group obtained the individual patient data that comprised the averaged data. The research group has since taken several approaches to analyze the model with the individual …

Dimension-Breaking For Traveling Waves In Interfacial Flows, Matthew W. Seiders

Theses and Dissertations

Fluid flow models in two spatial dimensions with a one-dimensional interface are known to support overturned traveling solutions. Computational methods of solving the two-dimensional problem are well developed, even in the case of overturned waves. The three-dimensional problem is harder for three prominent reasons. First, some formulations of the two-dimensional problem do not extend to three-dimensions. The technique of conformal mapping is a prime example, as it is very efficient in two dimensions but does not have a three-dimensional equivalent. Second, some three-dimensional models, such as the Transformed Field Expansion method, do not allow for overturned waves. Third, computational time …

Mathematical Model Investigating The Effects Of Neurostimulation Therapies On Neural Functioning: Comparing The Effects Of Neuromodulation Techniques On Ion Channel Gating And Ionic Flux Using Finite Element Analysis, Kaia Lindberg

Mathematics Theses

Neurostimulation therapies demonstrate success as a medical intervention for individuals with neurodegenerative diseases, such as Parkinson’s and Alzheimer’s disease. Despite promising results from these treatments, the influence of an electric current on ion concentrations and subsequent transmembrane voltage is unclear. This project focuses on developing a unique cellular-level mathematical model of neurostimulation to better understand its e↵ects on neuronal electrodynamics. The mathematical model presented here integrates the Poisson-Nernst-Planck system of PDEs and Hodgkin-Huxley based ODEs to model the e↵ects of this neurotherapy on transmembrane voltage, ion channel gating, and ionic mobility. This system is decoupled using the Gauss-Seidel method and …

The Mathematical Modeling Of Ballet, Kendall Gibson

Mathematics Senior Capstone Papers

This project aims to analyze the connections between ballet and mathematics. Specifically, this project focuses on analyzing the three-dimensional surfaces created as a dancer performs ballet choreography. The primary goal is to use a Vicon motion capture system in conjunction with MATLAB to model the three-dimensional lines and surfaces created by a dancer’s legs as she performs specific ballet movements. The movements used for this experiment were a pique turn and a rond de jambe. The data was collected using sensors to create objects in Vicon to record the position of the ankle, knee, and hip of the working leg …

Modeling Public Opinion, Arden Baxter

Honors Program Theses

The population dynamics of public opinion have many similarities to those of epidemics. For example, models of epidemics and public opinion share characteristics like contact rates, incubation times, and recruitment rates. Generally, epidemic dynamics have been presented through epidemiological models. In this paper we adapt an epidemiological model to demonstrate the population dynamics of public opinion given two opposing viewpoints. We find equilibrium solutions for various cases of the system and examine the local stability. Overall, our system provides sociological insight on the spread and transition of a public opinion.

Mathematical Models Of Mosquito Populations, Hanna Reed

Honors Undergraduate Theses

The intent of this thesis is to develop ordinary differential equation models to better understand the mosquito population. We first develop a framework model, where we determine the condition under which a natural mosquito population can persist in the environment. Wolbachia is a bacterium which limits the replication of viruses inside the mosquito which it infects. As a result, infecting a mosquito population with Wolbachia can decrease the transmission of viral mosquito-borne diseases, such as dengue. We develop another ODE model to investigate the invasion of Wolbachia in a mosquito population. In a biologically feasible situation, we determine three coexisting …

Comparison Of The Regulatory Dynamics Of Related Small Gene Regulatory Networks That Control The Response To Cold Shock In Saccharomyces Cerevisiae, Natalie Williams

Honors Thesis

The Dahlquist Lab investigates the global, transcriptional response of Sacchromyces cerevisiae, baker’s yeast, to the environmental stress of cold shock, using DNA microarrays for the wild type strain and strains deleted for a particular regulatory transcription factor. Gene regulatory networks (GRNs) consist of transcription factors (TF), genes, and the regulatory connections between them that control the resulting mRNA and protein expression levels. We use mathematical modeling to determine the dynamics of the GRN controlling the cold shock response to determine the relative influence of each transcription factor in the network. A family of GRNs has been derived from the …

The Role Of Mathematical Modeling In Designing And Evaluating Antimicrobial Stewardship Programs, Lester Caudill, Joanna R. Wares

Department of Math & Statistics Faculty Publications

Antimicrobial agent effectiveness continues to be threatened by the rise and spread of pathogen strains that exhibit drug resistance. This challenge is most acute in healthcare facilities where the well-established connection between resistance and sub-optimal antimicrobial use has prompted the creation of antimicrobial stewardship programs (ASPs). Mathematical models offer tremendous potential for serving as an alternative to controlled human experimentation for assessing the effectiveness of ASPs. Models can simulate controlled randomized experiments between groups of virtual patients, some treated with the ASP measure under investigation, and some without. By removing the limitations inherent in human experimentation, including health risks, study …

Roles Of A Teacher And Researcher During In Situ Professional Development Around The Implementation Of Mathematical Modeling Tasks, Hyunyi Jung, Corey Brady

University Faculty Publications and Creative Works

Partnership with teachers for professional development has been considered beneficial because of the potential of collaborative work in the teacher’s own classroom to be relevant to practice. From this perspective, both teachers and researchers can draw on their own expertise and work as authentic partners. In this study, we address the need for such collaboration and focus on how a teacher and a researcher performed their roles when collaboratively implementing mathematical modeling tasks within a context of in situ professional development. Using multi-tier design-based research, as a framework, a researcher worked in a teacher’s classroom to implement a series of …

Modeling Of Piezoelectric Traveling Wave Rotary Ultrasonic Motors With The Finite Volume Method, Ivan Arturo Renteria Marquez

Open Access Theses & Dissertations

In 1983 Toshiiku Sashida developed a new motor concept called Piezoelectric Traveling Wave Rotary Ultrasonic Motor (PTRUSM). The advantages of these motors include high torque at low speed, absence of a generated magnetic field, and high potential for miniaturization. Unfortunately PTRUSMs have some disadvantages that limit the areas of applications for these types of motors. The disadvantages are a short operating life (about 1000 hours), small output power, and the need of a complex motor controller.

On one hand, these motors have been used in satellites, mobile phones, photocopiers, robotic arms, telescopes, automobiles, and camera autofocusing. On the other hand, …

Mathematical Modeling Of Emiliania Huxleyi And A Host-Specific Virus, Julia Middleton

Honors Theses

The world’s oceans provide the basis for life on the planet. One microscopic algae, the coccolithophores, and Emiliania huxleyi in particular, is a major source of carbon drawdown in the context of the global carbon cycle and account for a significant amount of the primary production in oceanic ecosystems. We know that the oceans are packed with marine viruses and they have an important role in the rise and fall of plankton populations but current mathematical models do not accurately account for virus-host interactions when predicting plankton blooms. Therefore I am using model optimization and comparison techniques to evaluate current …

Mathematical Equations And System Identification Models For A Portable Pneumatic Bladder System Designed To Reduce Human Exposure To Whole Body Shock And Vibration, Ezzat Aziz Ayyad

UNLV Theses, Dissertations, Professional Papers, and Capstones

A mathematical representation is sought to model the behavior of a portable pneumatic foam bladder designed to mitigate the effects of human exposure to shock and whole body random vibration. Fluid Dynamics principles are used to derive the analytic differential equations used for the physical equations Model. Additionally, combination of Wiener and Hammerstein block oriented representation techniques have been selected to create system identification (SID) block oriented models. A number of algorithms have been iterated to obtain numerical solutions for the system of equations which was found to be coupled and non-linear, with no analytic closed form solution. The purpose …

Airborne Wireless Communication Modeling And Analysis With Matlab, Matthew J. Vincie

Theses and Dissertations

Over the past decade, there has been a dramatic increase in the use of unmanned aerial vehicles (UAV) for military, commercial, and private applications. Critical to maintaining control and a use for these systems is the development of wireless networking systems [1]. Computer simulation has increasingly become a key player in airborne networking developments though the accuracy and credibility of network simulations has become a topic of increasing scrutiny [2-5]. Much of the inaccuracies seen in simulation are due to inaccurate modeling of the physical layer of the communication system. This research develops a physical layer model that combines antenna …

Social Aggregation In Pea Aphids: Experiment And Random Walk Modeling, Christa Nilsen, John Paige, Olivia Warner, Benjamin Mayhew, Ryan Sutley, Matthew Lam '15, Andrew J. Bernoff, Chad M. Topaz

All HMC Faculty Publications and Research

From bird flocks to fish schools and ungulate herds to insect swarms, social biological aggregations are found across the natural world. An ongoing challenge in the mathematical modeling of aggregations is to strengthen the connection between models and biological data by quantifying the rules that individuals follow. We model aggregation of the pea aphid, Acyrthosiphon pisum. Specifically, we conduct experiments to track the motion of aphids walking in a featureless circular arena in order to deduce individual-level rules. We observe that each aphid transitions stochastically between a moving and a stationary state. Moving aphids follow a correlated random walk. …

Mathematical Modeling Of Fluid Spills In Hydraulically Fractured Well Sites, Oluwafemi Michael Taiwo

Graduate Theses and Dissertations

Improved drilling technology and favorable energy prices have contributed to the rapid pace at which the exploitation of unconventional natural gas is taking place across the United States. As a natural gas well is being drilled, reserve pits are constructed to hold the drilling fluids and other materials returned from the drilling process. These reserve pits can fail, and when they do, plant and animal life of the surrounding area may be adversely affected. This project develops a screening tool for a suitable location for a reserve pit. This work will be a critical piece of the Infrastructure Placement Analysis …

Optimization Models For Designing Spatially Compact Ecological Reserve Systems, Lakmali Weerasena

All Theses

Over the past decades, a number of mathematical models and solution techniques have been developed to preserve reserve sites for species and their natural habitats. Two optimization models for designing spatially compact ecological reserve systems are addressed here as zero-one integer programming problems. These formulations have a bicriteria objective function that is a combination of both boundary length and distance. The two formulations cluster the sites into a relatively small number of compact groups while preserving a required number of sites that contain a certain species using a given amount of resources. Two general types of approaches have been developed …

Mathematical Aids Epidemic Model: Preferential Anti-Retroviral Therapy Distribution In Resource Constrained Countries, Nadia Abuelezam

HMC Senior Theses

HIV/AIDS is one of the largest health problems the world is currently facing. Even with anti-retroviral therapies (ART), many resource-constrained countries are unable to meet the treatment needs of their infected populations. ART-distribution methods need to be created that prevent the largest number of future HIV infections. We have developed a compartment model that tracks the spread of HIV in multiple two-sex populations over time in the presence of limited treatment. The model has been fit to represent the HIV epidemic in rural and urban areas in Uganda. With the model we examine the spread of HIV among urban and …

Optimal Therapy Regimens For Treatment-Resistant Mutations Of Hiv, Weiqing Gu, Helen Moore

All HMC Faculty Publications and Research

In this paper, we use control theory to determine optimal treatment regimens for HIV patients, taking into account treatment-resistant mutations of the virus. We perform optimal control analysis on a model developed previously for the dynamics of HIV with strains of various resistance to treatment (Moore and Gu, 2005). This model incorporates three types of resistance to treatments: strains that are not responsive to protease inhibitors, strains not responsive to reverse transcriptase inhibitors, and strains not responsive to either of these treatments. We solve for the optimal treatment regimens analytically and numerically. We find parameter regimes for which optimal dosing …

A Mathematical Model For Treatment-Resistant Mutations Of Hiv, Helen Moore, Weiqing Gu

All HMC Faculty Publications and Research

In this paper, we propose and analyze a mathematical model, in the form of a system of ordinary differential equations, governing mutated strains of human immunodeficiency virus (HIV) and their interactions with the immune system and treatments. Our model incorporates two types of resistant mutations: strains that are not responsive to protease inhibitors, and strains that are not responsive to reverse transcriptase inhibitors. It also includes strains that do not have either of these two types of resistance (wild-type virus) and strains that have both types. We perform our analysis by changing the system of ordinary differential equations (ODEs) to …

Modeling Basketball Free Throws, Andrew Lang, Joerg M. Gablonsky

College of Science and Engineering Faculty Research and Scholarship

This paper presents a mathematical model for basketball free throws. It is intended to be a supplement to an existing calculus course and could easily be used as a basis for a calculus project. Students will learn how to apply calculus to model an interesting real-world problem, from problem identification all the way through to interpretation and verification. Along the way we will introduce topics such as optimization (univariate and multiobjective), numerical methods, and differential equations.