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Mathematical modeling

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Full-Text Articles in Applied Mathematics

Differential Equation Modeling For Sustainable Resource Management: A Steady-State Optimal Harvesting Approach, Iordanka N. Panayotova, Aleksei Talonov Sep 2026

Differential Equation Modeling For Sustainable Resource Management: A Steady-State Optimal Harvesting Approach, Iordanka N. Panayotova, Aleksei Talonov

CODEE Journal

Mathematical models based on differential equations provide a powerful framework for connecting real-world data to informed decision-making. In this work, we present a student-accessible project that uses an optimal-control framework to study the sustainable management of biological resources.

Motivated by fisheries management, we examine a predator--prey system in which harvesting decisions must balance ecological and economic considerations. The model is formulated as an optimal control problem that seeks to maximize the total discounted net revenue from harvesting. Rather than solving for the complete time-dependent harvesting trajectory, we restrict the analysis to positive controlled coexistence equilibria and characterize an interior stationary …


From Cork To Coasting: A Multi-Stage Ode Model Of Water-Rocket Flight, Viktoria Savatorova, Patryk Kustra, Ethan Dyer, Connor Carlson, Aleksei Talonov Jun 2026

From Cork To Coasting: A Multi-Stage Ode Model Of Water-Rocket Flight, Viktoria Savatorova, Patryk Kustra, Ethan Dyer, Connor Carlson, Aleksei Talonov

CODEE Journal

Water rockets provide an affordable and engaging context for exploring applications of differential equations. Motivated by outreach activities conducted with undergraduate students, we develop a four-stage mathematical model of vertical water-rocket flight that is suitable for use in an ODE or mathematical modeling course. The model includes the cork-release phase, water-thrust propulsion, air-thrust propulsion with compressible and potentially choked flow, and the final ballistic stage with quadratic drag. While retaining key physical features, the model can be formulated as a system of ordinary differential equations that can be integrated numerically using tools familiar to students. We compare model predictions with …


Memory Effects In Many-Body Systems, Jeffrey Beckstrand Jan 2026

Memory Effects In Many-Body Systems, Jeffrey Beckstrand

Master's Projects

This thesis investigates memory effects in many-body systems through the MoriZwanzig Formalism for projected dynamics of a Hamiltonian System which yields the Generalized Langevin Equation (GLE). The GLE is a stochastic differential equation (SDE) that studies the dynamics of observables under the effects of many other observables in the system. Although satisfying, the GLE has a term called the Memory Kernel that encodes the past of the system and introduces a computational challenge by introducing a non-Markovian property to the equation. The kernel is often approximated by introducing a delta function, which simplifies the computation, but at the loss of …


Using L1-Magic For Feature Enhancement And Reduced Redundancy In Hyperspectral Data, Ashley Alfred Jan 2026

Using L1-Magic For Feature Enhancement And Reduced Redundancy In Hyperspectral Data, Ashley Alfred

Mathematics Dissertations

Hyperspectral imaging offers detailed spectral information, but achieving high spatial resolution typically requires large and expensive equipment. This study explores an alternative approach: enhancing low-quality hyperspectral bands using an L1-norm minimization technique known as L1-magic. The goal is to improve the utility of low-cost hardware by preserving discriminative features, promoting sparsity, and reducing spectral redundancy. We apply L1-magic to enhance low-quality bands and hypothesize that this method selectively amplifies key features while suppressing redundant information. Experimental results indicate that the enhanced bands approach the quality of high-resolution data, enabling robust feature extraction without reliance on high-end hyperspectral cameras.


Mathematical Analysis And Numerical Simulation Of A Fractional-Order Sir-Si Model For Malaria Transmission Dynamics, Gassan A. M. O. Farah, Abdulaziz Y. A. Mukhtar, Kailash C. Patidar Dec 2025

Mathematical Analysis And Numerical Simulation Of A Fractional-Order Sir-Si Model For Malaria Transmission Dynamics, Gassan A. M. O. Farah, Abdulaziz Y. A. Mukhtar, Kailash C. Patidar

Mathematical Modelling and Numerical Simulation with Applications

This study investigates the complex transmission dynamics of malaria, a critical global health challenge, with a focus on the African continent. We introduce a novel approach that employs Fractional Differential Equations (FDEs) to advance the understanding of malaria spread and control. Specifically, we develop a new SIR-SI model using the Caputo fractional operator, which captures the memory effects and time-delay characteristics inherent in real-world epidemiological systems. A detailed analysis of the model's solvability and uniqueness is conducted using fixed-point theory. To obtain an analytical solution, the system is solved via the Laplace transform method, with solutions expressed in closed form …


Project-Based Learning With Odes: Modeling Straw Rocket Motion With Air Resistance, Viktoria Savatorova, Ethan Dyer, Aleksei Talonov Aug 2025

Project-Based Learning With Odes: Modeling Straw Rocket Motion With Air Resistance, Viktoria Savatorova, Ethan Dyer, Aleksei Talonov

CODEE Journal

This paper presents a hands-on project that guides students through building and validating a mathematical model of projectile motion. The project starts with the idealized case of motion under gravity without air resistance and then introduces air drag : first as a linear force, and then as a nonlinear quadratic force, with the Reynolds number providing the justification for the quadratic model. Students perform experiments with vertical and angled launches, capturing and analyzing motion data using video analysis software. Vertical launch data allows parameter estimation via least squares fitting of the nonlinear drag model, yielding values for initial velocity and …


Gain Threshold Optimization Using Fano Resonance, Alina Oktiabrskaia Jul 2025

Gain Threshold Optimization Using Fano Resonance, Alina Oktiabrskaia

LSU Doctoral Dissertations

The study of resonances in electromagnetics plays a critical role in the design of optical systems. This dissertation investigates the interaction between resonance and gain in optical structures to establish a universal principle for achieving ultra-low-threshold lasing. Through the analysis of geometric symmetries, material properties, and coupling mechanisms, this research develops prototype structures applicable to a wide range of optical and electromagnetic systems. A range of models is considered, starting from a simple onedimensional string-resonator system (based on the model of H. Lamb), then advancing to two- and three-dimensional waveguide models, and culminating with a realistic high-contrast model in open …


Suntan (And Other Solar Tigonometric Functions), John Adam Jan 2025

Suntan (And Other Solar Tigonometric Functions), John Adam

Mathematics & Statistics Faculty Publications

Question 1: If I₀ is the solar irradiance (power per unit area, W/m²) reaching my head, express the intensity on the side of my face (Is) in terms of θ. Assume for now that the irradiance is independent of path length through the atmosphere and that my face is normal to the direction θ = 90°.

Using the 1962 U.S. Standard Atmosphere,² Hottel (1976)³ expressed the solar irradiance using the formula

I = I₀(a₀ + a₁e−k sec θ), where A is the elevation in kilometers and

a₀ = 0.4237 − 0.00821(6 − A)²; a₁ = 0.5055 …


Investigating The Temperature Effects On Aedes Aegypti And Dengue Virus In Central Argentina: Perspectives From Mathematical Modeling, Morgan H. Jackson Jan 2025

Investigating The Temperature Effects On Aedes Aegypti And Dengue Virus In Central Argentina: Perspectives From Mathematical Modeling, Morgan H. Jackson

Theses and Dissertations

Dengue virus (DENV) causes over 390 million infections and around 40,000 deaths worldwide each year. DENV is primarily transmitted by the mosquito Aedes aegypti, and both the life cycle of these mosquitoes and DENV transmission are significantly impacted by temperature. In the temperate region of Central Argentina, where dengue outbreaks first began in 2009, outbreaks only occur following new introductions of DENV from other regions. Due to the relationships between temperature and DENV and temperature and Ae. aegypti, the risk of an outbreak changes throughout the year. Here, we develop and analyze mathematical models for both mosquito population dynamics and …


Enhancing Mathematical Models For Covid-19 Pandemic Response: A Philippine Study, Timothy Robin Teng, Elvira De Lara-Tuprio, Ma. Regina Justina Estuar, Christian Pulmano, Lu Christian S. Ong, Zachary Pangan, Lenard Paulo V. Tamayo, Jasper John V. Segismundo, Mark Anthony C. Tolentino, Alyssa Nicole N. Ty Dec 2024

Enhancing Mathematical Models For Covid-19 Pandemic Response: A Philippine Study, Timothy Robin Teng, Elvira De Lara-Tuprio, Ma. Regina Justina Estuar, Christian Pulmano, Lu Christian S. Ong, Zachary Pangan, Lenard Paulo V. Tamayo, Jasper John V. Segismundo, Mark Anthony C. Tolentino, Alyssa Nicole N. Ty

Mathematics Faculty Publications

Mathematical models supported by a robust automated data pipeline proved to be useful tools for a data-driven and science-based response and policy-making during the COVID-19 pandemic in the Philippines. In the first year of the pandemic, FASSSTER (Feasibility Analysis on Syndromic Surveillance using Spatio-Temporal Epidemiological modeleR) used a compartmental model to generate scenario-based projections of COVID-19 cases. The emergence of the Delta variant, however, and the administration of vaccines over the second half of 2021 caused significant changes in the Philippine pandemic landscape. This necessitated making adjustments to the model to better capture the local disease transmission dynamics and address …


Large Deviation Theory In Stochastic Processes: Applications To Biological Modeling, Moshe C. Silverstein Aug 2024

Large Deviation Theory In Stochastic Processes: Applications To Biological Modeling, Moshe C. Silverstein

Dissertations

This dissertation delves into developing and applying stochastic models to analyze complex biological systems. It leverages Large Deviation Theory (LDT) to gain insights into these systems, focusing on two key examples: neural networks and calcium signaling dynamics. Traditional deterministic methods frequently fail to capture biological processes' randomness and inherent variability. Meanwhile, many stochastic approaches struggle to be mathematically tractable or provide accessible insights. The approach introduced in this study provides rigorous mathematical frameworks to enhance understanding of these stochastic behaviors while remaining tractable and insightful.

A stochastic model for a random biological neural network is constructed that addresses the dependencies …


Frameworks For The Techno-Economic Assessment Of Membrane-Based Bioprocessing Platforms, Juan Jose Romero Conde Aug 2024

Frameworks For The Techno-Economic Assessment Of Membrane-Based Bioprocessing Platforms, Juan Jose Romero Conde

All Dissertations

This dissertation describes developing and implementing computational frameworks for simulating and optimizing purification processes in the biopharmaceutical industry. The framework performs techno-economic analyses to establish value propositions for new process alternatives, especially membrane technologies. Initially, the focus is developing a framework capable of simulating monoclonal antibody (mAb) capture using membrane and resin media in multi-column chromatography (MCC) platforms for continuous manufacturing. Subsequently, the impact of capture MCC is compared against other intensification strategies in established mAb manufacturing facilities. Finally, the framework application expands to simulate the purification of adeno-associated virus (AAV) vectors for gene therapy.

Chapter 2 details the framework …


Cell Motion And Multicellular Organization: A Mathematical Model For Pattern Formation In The Dictyostelium Discoideum Slug, Henry Tullis, Emily Evans, John Dallon Mar 2024

Cell Motion And Multicellular Organization: A Mathematical Model For Pattern Formation In The Dictyostelium Discoideum Slug, Henry Tullis, Emily Evans, John Dallon

Library/Life Sciences Undergraduate Poster Competition 2024

Understanding multicellular behavior is key to biology and medicine

  • Embryonic development requires coordinated cell motion, differentiation
  • Wound healing also relies on emergent multicellular processes
  • Dictyostelium discoideum (Dd) has been identified as a model organism for biomedical research, partly because it is a simple example of multicellularity
  • Understanding Dd can improve, inform approaches to these tricky problems


Raising Student Awareness Of Environmental Issues Via Writing Assignments With Differential Equations, Michelle L. Ghrist Jan 2024

Raising Student Awareness Of Environmental Issues Via Writing Assignments With Differential Equations, Michelle L. Ghrist

CODEE Journal

In this paper, I discuss two environmentally-focused writing assignments that I developed and implemented in recent integral calculus and differential equations courses. These models of carbon storage and PCB’s in a river provide interesting applications of one-compartment mixing problems. The assignments were intended to focus student attention on sustainability concerns while also developing other essential skills. I discuss these assignments and their effect on my students’ technical writing and environmental awareness. Detailed introductory instructions and mostly complete solutions to these assignments appear in the appendices, to include sample student work.


Mathematical Modeling Of Microscale Biology In Polyelectrolyte Brushes, William J. Ceely Jan 2024

Mathematical Modeling Of Microscale Biology In Polyelectrolyte Brushes, William J. Ceely

CGU Theses & Dissertations

Biological macromolecules including nucleic acids, proteins, and glycosaminoglycans are typically anionic and can span domains of up to hundreds of nanometers and even micron length scales. The structures exist in crowded environments that are dominated by multivalent electrostatic interactions that can be modeled using mean-field continuum approaches that represent underlying molecular nanoscale biophysics. In this thesis, we develop such models for polyelectrolyte brushes using both steady state modified Poisson-Boltzmann models and transient modified Poisson-Nernst-Planck models that incorporate important ion-specific (Hofmeister) effects. The transient model enables observation of the relative physical effects as an initial non-equilibrium state relaxes to the steady …


Mathematical Modeling Of Coupled Heat And Mass Transfer In Metal-Hydride Hydrogen Storage Systems, Muhammad Hasnain Jan 2024

Mathematical Modeling Of Coupled Heat And Mass Transfer In Metal-Hydride Hydrogen Storage Systems, Muhammad Hasnain

College of Graduate Studies: Theses & Dissertations

As a promising clean energy carrier hydrogen has recently gained significant interest, but its efficient and safe storage is a major challenge. Compared to the gaseous state and liquid state, metal hydrides (MH) offer a potentially more effective storage approach for hydrogen. However, the main challenge in this approach is the low thermal conductivity of the MH bed that leads to low heat transfer and ultimately to higher charging and discharging times. The purpose of this work is to develop an in-house comprehensive heat and mass transfer model for hydrogen sorption in MH reactors to simulate the dynamic behavior of …


Mathematical Analysis Of Eukaryotic Pericentromere, Puranjan Ghimire Jan 2024

Mathematical Analysis Of Eukaryotic Pericentromere, Puranjan Ghimire

Theses and Dissertations

The centromere is crucial for chromosomal stability and their proper segregation during cell division in eukaryotes. Surrounding the centromere are pericentromeres, made of repetitive DNA elements called pericentromeric repeats, varying from 10 in fission yeast to thousands in humans. These repeats form densely packed heterochromatin, where genes are usually silenced. The silencing mechanism across different pericentromeric repeats remains unclear.

Despite variations in sequence and length, pericentromeric repeats are conserved across eukaryotes, indicating their functional importance. This dissertation presents mathematical models to quantify gene silencing in fission yeast and humans. In fission yeast, my model predicts that silencing occurs only with …


An Integrated Experimental And Modeling Approach To Design Rotating Algae Biofilm Reactors (Rabrs) Via Optimizing Algae Biofilm Productivity, Nutrient Recovery, And Energy Efficiency, Gerald Benjamin Jones May 2023

An Integrated Experimental And Modeling Approach To Design Rotating Algae Biofilm Reactors (Rabrs) Via Optimizing Algae Biofilm Productivity, Nutrient Recovery, And Energy Efficiency, Gerald Benjamin Jones

All Graduate Plan B and other Reports, Spring 1920 to Spring 2023

Microalgae biofilms have been demonstrated to recover nutrients from wastewater and serve as biomass feedstock for bioproducts. However, there is a need to develop a platform to quantitatively describe microalgae biofilm production, which can provide guidance and insights for improving biomass areal productivity and nutrient uptake efficiency. This paper proposes a unified experimental and theoretical framework to investigate algae biofilm growth on a rotating algae biofilm reactor (RABR). The experimental laboratory setups are used to conduct controlled experiments on testing environmental and operational factors for RABRs. We propose a differential-integral equation-based mathematical model for microalgae biofilm cultivation guided by laboratory …


Mathematical Modeling: Finite Element Analysis And Computations Arising In Fluid Dynamics And Biological Applications, Jorge Reyes May 2023

Mathematical Modeling: Finite Element Analysis And Computations Arising In Fluid Dynamics And Biological Applications, Jorge Reyes

UNLV Theses, Dissertations, Professional Papers, and Capstones

It is often the case when attempting to capture real word phenomena that the resulting mathematical model is too difficult and even not feasible to be solved analytically. As a result, a computational approach is required and there exists many different methods to numerically solve models described by systems of partial differential equations. The Finite Element Method is one of them and it was pursued herein.This dissertation focuses on the finite element analysis and corresponding numerical computations of several different models. The first part consists of a study on two different fluid flow models: the main governing model of fluid …


A Mathematical Modeling Technique To Understand The Role Of Decoy Receptors In Ligand‑Receptor Interaction, Subrata Dey, Aditi Ghosh, Malay Banerjee Jan 2023

A Mathematical Modeling Technique To Understand The Role Of Decoy Receptors In Ligand‑Receptor Interaction, Subrata Dey, Aditi Ghosh, Malay Banerjee

Faculty Publications

The ligand‑receptor interaction is fundamental to many cellular processes in eukaryotic cells such as cell migration, proliferation, adhesion, signaling and so on. Cell migration is a central process in the development of organisms. Receptor induced chemo‑tactic sensitivity plays an important role in cell migration. However, recently some receptors identified as decoy receptors, obstruct some mechanisms of certain regular receptors. DcR3 is one such important decoy receptor, generally found in glioma cell, RCC cell and many various malignant cells which obstruct some mechanism including apoptosis cell‑signaling, cell inflammation, cell migration. The goal of our work is to mathematically formulate ligand‑receptor interaction …


Stochastic Modeling Of Flows In Membrane Pore Networks, Binan Gu Aug 2022

Stochastic Modeling Of Flows In Membrane Pore Networks, Binan Gu

Dissertations

Membrane filters provide immediate solutions to many urgent problems such as water purification, and effective remedies to pressing environmental concerns such as waste and air treatment. The ubiquity of applications gives rise to a significant amount of research in membrane material selection and structural design to optimize filter efficiency. As physical experiments tend to be costly, numerical simulation and analysis of fluid flow, foulant transport and geometric evolution due to foulant deposition in complex geometries become particularly relevant. In this dissertation, several mathematical modeling and analytical aspects of the industrial membrane filtration process are investigated. A first-principles mathematical model for …


A New Sir Model With Mobility., Ciana Applegate Aug 2022

A New Sir Model With Mobility., Ciana Applegate

Electronic Theses and Dissertations

In this paper, a mobility-based SIR model is built to understand the spread of the pandemic. A traditional SIR model used in epidemiology describes the transition of particles among states, such as susceptible, infected, and recovered states. However, the traditional model has no movement of particles. There are many variations of SIR models when it comes to the factor of mobility, the majority of studies use mobility intensity or population density as a measure of mobility. In this paper, a new dynamical SIR model, including the spatial motion of three-type particles, is constructed and the long-time behavior of the first …


Mentoring Undergraduate Research In Mathematical Modeling, Glenn Ledder Jun 2022

Mentoring Undergraduate Research In Mathematical Modeling, Glenn Ledder

Department of Mathematics: Faculty Publications

In writing about undergraduate research in mathematical modeling, I draw on my 31 years as a mathematics professor at the University of Nebraska–Lincoln, where I mentored students in honors’ theses, REU groups, and research done in a classroom setting, as well as my prior experience. I share my views on the differences between research at the undergraduate and professional levels, offer advice for undergraduate mentoring, provide suggestions for a variety of ways that students can disseminate their research, offer some thoughts on mathematical modeling and how to explain it to undergraduates, and discuss the challenges involved in broadening research participation …


Mentoring Undergraduate Research In Mathematical Modeling, Glenn Ledder Jun 2022

Mentoring Undergraduate Research In Mathematical Modeling, Glenn Ledder

Department of Mathematics: Faculty Publications

In writing about undergraduate research in mathematical modeling, I draw on my 31 years as a mathematics professor at the University of Nebraska–Lincoln, where I mentored students in honors’ theses, REU groups, and research done in a classroom setting, as well as my prior experience. I share my views on the differences between research at the undergraduate and professional levels, offer advice for undergraduate mentoring, provide suggestions for a variety of ways that students can disseminate their research, offer some thoughts on mathematical modeling and how to explain it to undergraduates, and discuss the challenges involved in broadening research participation …


A Mathematical Model For The Adoption Of Information And Communication Technology In School Libraries In Nigeria, Helen Olubunmi Jaiyeola Akinade, Jeremiah Ademola Balogun, Peter Adebayo Idowu Apr 2022

A Mathematical Model For The Adoption Of Information And Communication Technology In School Libraries In Nigeria, Helen Olubunmi Jaiyeola Akinade, Jeremiah Ademola Balogun, Peter Adebayo Idowu

Library Philosophy and Practice (e-journal)

This study focused on the development of a mathematical model required for estimating the number of adopters of ICT devices among libraries located in Nigeria. Data for this study was collected from 121 respondents selected based on a research survey approach using simple random sampling. 9 ICT devices were identified, namely: PCs, printers/fax machines, search engines, e-library systems, bulk SMS services, library management systems, bar/QR code readers, projectors and video conferencing. The results showed that the earliest ICT devices were adopted for use in 1997, such as: PCs, printers/fax machines and search engines. The remaining ICT devices were adopted in …


Numerical Study Of Highly Efficient Centrifugal Cyclones, Murodil Madaliev Mar 2022

Numerical Study Of Highly Efficient Centrifugal Cyclones, Murodil Madaliev

Scientific-technical journal

Centrifugal cyclones have been developing for 100 years, while the efficiency of all cyclones for fine dust does not increase by 80%. The widespread use of cyclones in all branches of industrial production is determined by the simplicity of the design and sufficient reliability in operation. Along with this, the process carried out in a cyclone presents a complex scientific problem that has not been solved from the standpoint of aerohydromechanics. This is confirmed by various cyclone designs. Currently, the efficiency of cyclone cleaning of technological flows does not meet the requirements of sanitary standards and largely determines the level …


Mathematical Models Of Infection Prevention Programs In Hospital Settings, Kelly A. Reagan Jan 2022

Mathematical Models Of Infection Prevention Programs In Hospital Settings, Kelly A. Reagan

Theses and Dissertations

Hospitals play a vital role in providing for the healthcare needs of a community. Patients can develop hospital-acquired infections (HAIs) during their hospitalization due to exposure to foreign bacteria, viruses, and fungi. Infection prevention programs target and reduce HAIs, but implementing the infection prevention programs often comes with a cost. The goal of my research is to use mathematical models to quantify the impact of infection prevention programs on cases of HAIs and total healthcare costs. First, I use a Markov chain model to quantify how one infection prevention program reduces general HAIs in the hospital. Then, I calculate the …


Modeling Dewetting, Demixing, And Thermal Effects In Nanoscale Metal Films, Ryan Howard Allaire Aug 2021

Modeling Dewetting, Demixing, And Thermal Effects In Nanoscale Metal Films, Ryan Howard Allaire

Dissertations

Thin film dynamics, particularly on the nanoscale, is a topic of extensive interest. The process by which thin liquids evolve is far from trivial and can lead to dewetting and drop formation. Understanding this process involves not only resolving the fluid mechanical aspects of the problem, but also requires the coupling of other physical processes, including liquid-solid interactions, thermal transport, and dependence of material parameters on temperature and material composition. The focus of this dissertation is on the mathematical modeling and simulation of nanoscale liquid metal films, which are deposited on thermally conductive substrates, liquefied by laser heating, and subsequently …


Modeling And Design Optimization For Membrane Filters, Yixuan Sun Aug 2021

Modeling And Design Optimization For Membrane Filters, Yixuan Sun

Dissertations

Membrane filtration is widely used in many applications, ranging from industrial processes to everyday living activities. With growing interest from both industrial and academic sectors in understanding the various types of filtration processes in use, and in improving filter performance, the past few decades have seen significant research activity in this area. Experimental studies can be very valuable, but are expensive and time-consuming, therefore theoretical studies offer potential as a cost-effective and predictive way to improve on current filter designs. In this work, mathematical models, derived from first principles and simplified using asymptotic analysis, are proposed for: (1) pleated membrane …


A Computational Investigation Of The Biophysical Mechanisms Underlying Thermotaxis In The Afd Neurons Of Caenorhabditis Elegans, Zachary Mobille Mar 2021

A Computational Investigation Of The Biophysical Mechanisms Underlying Thermotaxis In The Afd Neurons Of Caenorhabditis Elegans, Zachary Mobille

Theses and Dissertations

Thermotaxis in the nematode Caenorhabditis elegans (C. elegans) is studied at the cellular scale of the amphid finger-like ciliated (AFD) neurons, which have previously been shown to be essential for thermoreception. The voltage and calcium signals of AFD during temperature stimuli are described with ordinary differential equations. The primary calcium model is a modified version of that published by Kuramochi and Doi in 2017 to explain the calcium responses of the chemosensitive amphid single-ciliated right (ASER) neuron to fluctuations in extracellular salt concentration. To account for the effects of temperature, changes to the stimuli conditions under which inactivation takes place …