Open Access. Powered by Scholars. Published by Universities.®
- Institution
-
- Taylor University (473)
- University of New Mexico (368)
- University of Nebraska - Lincoln (190)
- Prairie View A&M University (163)
- Wright State University (144)
-
- University of Dayton (142)
- Claremont Colleges (134)
- Wayne State University (105)
- Technological University Dublin (89)
- Portland State University (54)
- City University of New York (CUNY) (44)
- Rose-Hulman Institute of Technology (44)
- Utah State University (43)
- Old Dominion University (42)
- Western Kentucky University (42)
- Illinois State University (41)
- Virginia Commonwealth University (39)
- Illinois Wesleyan University (28)
- University of Texas Rio Grande Valley (25)
- East Tennessee State University (22)
- Kennesaw State University (21)
- Association of Arab Universities (19)
- Louisiana Tech University (19)
- Southern Illinois University Carbondale (19)
- University of Kentucky (19)
- Western Michigan University (19)
- California Polytechnic State University, San Luis Obispo (18)
- University of Nevada, Las Vegas (18)
- Georgia Southern University (16)
- Montclair State University (16)
- Keyword
-
- Mathematics (70)
- Neutrosophic logic (49)
- Generalized differentiation (42)
- Variational analysis (42)
- Differential equations (32)
-
- Finite element method (32)
- Optimal control (19)
- Stability (19)
- Necessary optimality conditions (18)
- Optimization (18)
- Solitons (18)
- Mathematical modeling (16)
- Numerical analysis (16)
- Statistics (16)
- Graph theory (15)
- Machine Learning (14)
- Neutrosophic Logic (14)
- Geometry (13)
- Machine learning (13)
- Modeling (13)
- Algebra (12)
- Calculus (12)
- Partial differential equations (12)
- Physics (12)
- Algorithms (11)
- Boundary value problems (11)
- Galerkin methods (11)
- Simulation (11)
- Discrete approximations (10)
- Neutrosophy (10)
- Publication Year
- Publication
-
- Branch Mathematics and Statistics Faculty and Staff Publications (210)
- Department of Mathematics: Faculty Publications (169)
- Applications and Applied Mathematics: An International Journal (AAM) (163)
- Mathematics & Statistics ETDs (154)
- Mathematics and Statistics Faculty Publications (143)
-
- Mathematics Faculty Publications (120)
- Mathematics Research Reports (93)
- Articles (82)
- Summer Conference on Topology and Its Applications (62)
- All HMC Faculty Publications and Research (53)
- Mathematics and Statistics Faculty Publications and Presentations (49)
- Dissertations (39)
- Annual Symposium on Biomathematics and Ecology Education and Research (37)
- Mathematical Sciences Technical Reports (MSTR) (35)
- ACMS Conference Proceedings 2005 (34)
- Theses and Dissertations (31)
- ACMS Conference Proceedings 2013 (30)
- Electronic Theses and Dissertations (30)
- Scholarship (28)
- ACMS Conference Proceedings 2003 (27)
- ACMS Conference Proceedings 2011 (26)
- ACMS Conference Proceedings 2019 (26)
- ACMS Conference Proceedings 1999 (25)
- ACMS Conference Proceedings 2009 (25)
- Publications and Research (25)
- ACMS Conference Proceedings 2007 (23)
- ACMS Conference Proceedings 2015 (23)
- ACMS Conference Proceedings 2017 (22)
- ACMS Journal 2004 (22)
- ACMS Conference Proceedings 1997 (21)
- Publication Type
- File Type
Articles 91 - 120 of 2864
Full-Text Articles in Applied Mathematics
Understanding Enso Through Mathematical Models, Maria I. Sanchez Muniz
Understanding Enso Through Mathematical Models, Maria I. Sanchez Muniz
Open Educational Resources
This assignment introduces students to conceptual models of the El Niño–Southern Oscillation (ENSO) and guides them through a structured investigation of their physical and mathematical foundations. Students analyze the recharge–oscillator and delayed–oscillator frameworks, explore how differential equations capture ocean–atmosphere interactions, and evaluate parameter-driven changes in oscillatory behavior. A key component of the work is the guided use of generative AI as a research tool: students employ AI models to locate peer-reviewed literature, interrogate model extensions, and refine their understanding of complex mechanisms, while synthesizing all final explanations in their own words. By blending classical climate modeling with modern AI-supported inquiry, …
Universal Systems Simulation Via Constraint Hypergraphs With Applications To Digital Twins, John Morris
Universal Systems Simulation Via Constraint Hypergraphs With Applications To Digital Twins, John Morris
All Dissertations
The characterization of systems encompasses a variety of modeling frameworks designed to capture specific behaviors and components of various system domains. Whatever the framework, the core elements of a system representation are the information of the system and a description of how that information is related. The relations in deterministic systems are functions, which, when composed to form executable processes, can be used to simulate system data. A declarative modeling framework is one that encodes mechanisms for preparing these simulations within the model structure, allowing an external agent to form the execution processes required for a given context. To date, …
A Leslie System For A Demographic Simulation: From An Actuarial Point Of View, David Kings
A Leslie System For A Demographic Simulation: From An Actuarial Point Of View, David Kings
Electronic Theses and Dissertations
This thesis develops a discrete stochastic linear systems interpretation of age–stage demographic evolution grounded in Leslie operators and realized in a discrete-event simulation implemented with salabim. The central claim is that one annual cycle of the simulation constitutes a cone-preserving, stochastic affine transformation on a high- dimensional population state vector indexed by age, sex, marital status, household type, employment, and education, and that the composition of yearly operators yields a random matrix product whose top Lyapunov exponent is the stochastic counterpart of the Perron–Frobenius growth rate (Caswell, 2001; Tuljapurkar, 1997)[1, 2]. The actuarial bridge is constructed by mapping simulated survival …
On Sobolev Spaces And The Existence Of Weak Solutions To Boundary Value Problems, Skye X. Paul
On Sobolev Spaces And The Existence Of Weak Solutions To Boundary Value Problems, Skye X. Paul
Master's Theses
Many boundary value problems that arise in mathematical models have close connections to second order elliptic partial differential equations. This thesis introduces the idea of weak derivatives and Sobolev Spaces to generalize possible solutions. Using functional analysis centered around the Lax-Milgram theorem, we show the existence of these generalized solutions to boundary value problems including Laplace's Equation, 2nd order linear ODEs, and ultimately a general second order elliptic PDE. The work cumulates with recovering a number of central theorems of functional analysis in the context of Sobolev Spaces, creating a new perspective on the solvability of these boundary value problems.
An Income Subsystem As A Discrete Stochastic Leslie System: A Simulation-Based Approach, Fahd Nii Okantah Cobblah
An Income Subsystem As A Discrete Stochastic Leslie System: A Simulation-Based Approach, Fahd Nii Okantah Cobblah
Electronic Theses and Dissertations
This thesis formulates the household-income engine of an integrated population sim- ulator as a Discrete Stochastic Leslie System (DSLS). The nonnegative state vector nt ∈ Rk + aggregates income, savings, debt, employment, and transfers. (Here, the subscript + denotes the positive cone, i.e., vectors with nonnegative components). Annual evolution is linear in state, stochastic in coefficients: nt+1 = Ttnt + εt, with Tt : Rk + → Rk + cone-preserving. Exogenous macro drivers (inflation, employment, tax, salary inflation, mortgage) are forecast via ARIMA; forecasts multiply entries of Tt, preserving linearity in expectation while introducing realistic temporal correlation. The discrete-event implemented …
Estimation Of 3d Facial Dynamics With Nonlinear Filters For Position Tracking, Thoa Thieu, Roderick Melnik
Estimation Of 3d Facial Dynamics With Nonlinear Filters For Position Tracking, Thoa Thieu, Roderick Melnik
School of Mathematical & Statistical Sciences Faculty Publications
This study presents a comparative evaluation of three nonlinear state estimation filters, the Extended Kalman Filter (EKF), Unscented Kalman Filter (UKF), and Particle Filter (PF), for the task of 3D facial landmark tracking. Using a publicly available dataset, we assess each filter's performance under both deterministic (noise-free) and stochastic (noisy) conditions. Metrics such as mean squared error (MSE), convergence rates of state and covariance estimates, and consistency over time are used to quantify tracking performance. Results show that the EKF consistently outperforms the UKF and PF, achieving faster convergence and lower estimation error, particularly in scenarios characterized by mild nonlinearity. …
Comparing Machine Learning, Deep Learning, And Reinforcement Learning Performance In Culex Pipiens Predictive Modeling, Wei Yin, Sanad H. Ragab, Michael G. Tyshenko, Teresa Patricia Feria-Arroyo, Tamer Oraby
Comparing Machine Learning, Deep Learning, And Reinforcement Learning Performance In Culex Pipiens Predictive Modeling, Wei Yin, Sanad H. Ragab, Michael G. Tyshenko, Teresa Patricia Feria-Arroyo, Tamer Oraby
School of Mathematical & Statistical Sciences Faculty Publications
Several machine learning (ML) and deep learning (DL) methods have been used to predict the presence of species in classification problems. Another set of methods, called reinforcement learning (RL), has been used in training agents to perform various tasks, but not in predicting species distribution. Culex pipiens (Diptera: Culicidae), commonly known as the common house mosquito, is a globally distributed species prevalent in temperate and subtropical regions. They serve as a primary vector for West Nile Virus (WNV), a mosquito-borne pathogen that affects humans and other animals. The study objective is to compare the performance of logistic regression, random forest …
Modeling Synaptic Dysfunction As Neural Contagion: A Graph-Based Sedr Framework For Simulating Signal Spread, Michelle Marfo, Dr. Padmanabhan Seshaiyer, Alonso Ogueda-Oliva
Modeling Synaptic Dysfunction As Neural Contagion: A Graph-Based Sedr Framework For Simulating Signal Spread, Michelle Marfo, Dr. Padmanabhan Seshaiyer, Alonso Ogueda-Oliva
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Modeling The Cancer Cell Growth Predictions Based On Classical Mathematical Models With Physics-Informed Neural Network, Widodo Samyono
Modeling The Cancer Cell Growth Predictions Based On Classical Mathematical Models With Physics-Informed Neural Network, Widodo Samyono
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Invitation To Polynomiography Via Chatgpt: For Teachers, Students And Artists, Bahman Kalantari
Invitation To Polynomiography Via Chatgpt: For Teachers, Students And Artists, Bahman Kalantari
LASER Journal
Teachers, students, and artists in the United States and abroad who have encountered polynomiography, in lectures, demos, or software, consistently appreciate its educational value and artistic potential. While dedicated polynomiography programs require upkeep as systems evolve, AI chatbots now offer a practical, accessible alternative. This article invites readers to explore polynomiography with ChatGPT, broadening access beyond specialized tools. While the approach will not match the full range or polish of advanced software, it provides a powerful and flexible entry point with many possibilities.
At its core, polynomiography transforms polynomial equations, each encoding a finite set of points in the complex …
[Kadel] Parameter Personalization Of Medical Digital Twins, Logan Rose
[Kadel] Parameter Personalization Of Medical Digital Twins, Logan Rose
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Expanding Ode Examples: Introducing Gene Regulation Dynamics Through Hill Functions, Maila Hallare, Jane M. Santamore
Expanding Ode Examples: Introducing Gene Regulation Dynamics Through Hill Functions, Maila Hallare, Jane M. Santamore
CODEE Journal
Gene regulation is a fundamental biological process that controls gene expression. It can explain phenomena such as cell differentiation, circadian rhythms, disease progression, and metabolic control, among many others. Despite their importance in mathematical biology, gene regulation models are rarely featured in traditional ODE textbooks, which focus mainly on examples from engineering, physics, chemistry, and population biology. This article introduces gene regulation dynamics as a valuable addition to ODE curricula, presenting the models from a mathematical perspective and building on properties of the Hill function. These models deepen the understanding of biology-inspired ODE applications, provide accessible research opportunities for students, …
Paclobutrazol Enhances Tall Fescue Salt Tolerance Via Physiological And Root System Architecture Modulation, Shugao Fan, Xindi Sun, Guohao Liang, Zhuanzhuan Ma, Jincheng Hao, Jiawei Wu, Ying Zhao
Paclobutrazol Enhances Tall Fescue Salt Tolerance Via Physiological And Root System Architecture Modulation, Shugao Fan, Xindi Sun, Guohao Liang, Zhuanzhuan Ma, Jincheng Hao, Jiawei Wu, Ying Zhao
School of Mathematical & Statistical Sciences Faculty Publications
Background: Salinity represents a major global constraint on crop productivity. Promoting the cultivation of tall fescue in saline environments offers not only nutritional advantages for livestock but also enhances its potential for ornamental use. In this mesocosm study, we examined the effects of paclobutrazol (PBZ) on tall fescue performance under salt stress, focusing on key physiological traits to evaluate salt tolerance.
Results: Under high salt stress, paclobutrazol application increased the total number of lateral roots by 85%, from 18.39 to 34.04, and widened their growth angle by 24%, from 24.10° to 29.88°, fundamentally enhancing topsoil exploration. This reconfigured root system …
Tight Spherical Embeddings (Updated Version), Thomas E. Cecil, Patrick J. Ryan
Tight Spherical Embeddings (Updated Version), Thomas E. Cecil, Patrick J. Ryan
Mathematics and Computer Science Department Faculty Scholarship
This is an updated version of the paper [14] which appeared in the proceedings of the 1979 Berlin Colloquium on Global Differential Geometry. This paper contains the original exposition together with some notes by the authors made in 2025 (as indicated in the text) that give references to descriptions of progress made in the field since the time of the original version of the paper. The main result of this paper is that every compact isoparametric hypersurface Mn ⊂ Sn+1 ⊂ Rn+2 is tight, i.e., every non-degenerate linear height function ℓp, p ∈ …
Memoir On A General Property Of A Very Extensive Class Of Transcendental Functions, Niels Henrik Abel 1802--1829, John Little
Memoir On A General Property Of A Very Extensive Class Of Transcendental Functions, Niels Henrik Abel 1802--1829, John Little
Mathematics and Computer Science Department Faculty Scholarship
We present this new commentary and translation anticipating the 200th anniversary of the work, commonly known as Abel's ``Paris memoir.'' This is recognized today as one of Abel's most original and influential works. It is significant mostly because it marked the first appearance of a form of a result in the theory of algebraic curves and Riemann surfaces that has come to be known as ``Abel's theorem.'' However, Abel's original understanding of the meaning and context of his result was quite different from the typical modern formulation and the development of the modern understanding has been a long and tortuous …
Constructions Of Compact Dupin Hypersurfaces With Non-Constant Lie Curvatures, Thomas E. Cecil
Constructions Of Compact Dupin Hypersurfaces With Non-Constant Lie Curvatures, Thomas E. Cecil
Mathematics and Computer Science Department Faculty Scholarship
A hypersurface M in the unit sphere Sn ⊂ Rn+1 is Dupin if along each curvature surface of M, the corresponding principal curvature is constant. If the number g of distinct principal curvatures is constant on M, then M is called proper Dupin. In this expository paper, we give a detailed description of two important types of constructions of compact proper Dupin hypersurfaces in Sn. One construction was published in 1989 by Pinkall and Thorbergsson [35], and the second was published in 1989 by Miyaoka and Ozawa [26]. Both types of examples have the …
Analytical And Numerical Approaches To Parameter Estimation In Damped Oscillatory Systems, Gracie Crooks, F. Ayça Çetinkaya
Analytical And Numerical Approaches To Parameter Estimation In Damped Oscillatory Systems, Gracie Crooks, F. Ayça Çetinkaya
CODEE Journal
We investigate the inverse problem of identifying damping and stiffness parameters in one-dimensional damped oscillatory systems governed by second-order differential equations. Focusing on mass–spring–damper models, we analyze the qualitative behavior of solutions across underdamped, critically damped, and overdamped regimes, and derive explicit conditions for parameter recovery based on time-domain observations such as equilibrium crossings and turnaround points. Two numerical estimation methods are developed and compared: a finite-difference least-squares approach based on central difference approximations, and a finite element formulation derived from a variational framework using piecewise linear basis functions. Computational experiments using synthetic data assess the accuracy, stability, and noise …
Project-Based Learning With Odes: Modeling Straw Rocket Motion With Air Resistance, Viktoria Savatorova, Ethan Dyer, Aleksei Talonov
Project-Based Learning With Odes: Modeling Straw Rocket Motion With Air Resistance, Viktoria Savatorova, Ethan Dyer, Aleksei Talonov
CODEE Journal
This paper presents a hands-on project that guides students through building and validating a mathematical model of projectile motion. The project starts with the idealized case of motion under gravity without air resistance and then introduces air drag : first as a linear force, and then as a nonlinear quadratic force, with the Reynolds number providing the justification for the quadratic model. Students perform experiments with vertical and angled launches, capturing and analyzing motion data using video analysis software. Vertical launch data allows parameter estimation via least squares fitting of the nonlinear drag model, yielding values for initial velocity and …
Analysis Of Multi Grade Deep Learning, Ronglong Fang
Analysis Of Multi Grade Deep Learning, Ronglong Fang
Mathematics & Statistics Theses & Dissertations
Multi-Grade Deep Learning (MGDL) is a training framework that incrementally builds deep neural networks. It does this by dividing the training process into multiple “grades,” where each grade sequentially trains a shallow neural network to learn the residue from the previous one, using the outputs of prior grades as input. This approach progresses from shallow to deep architectures. This dissertation offers a comprehensive theoretical and numerical analysis of the MGDL methodology.
We first demonstrate that MGDL can effectively learn target functions within the sum-composition learning format. In this context, MGDL approximates high-frequency components by composing multiple low-frequency functions. This unique …
Algebraic Multigrid Methods For Nonsymmetric And Indefinite Problems: Theory And Applications, Ahsan Ali
Algebraic Multigrid Methods For Nonsymmetric And Indefinite Problems: Theory And Applications, Ahsan Ali
Mathematics & Statistics ETDs
Algebraic multigrid (AMG) is a well-established and highly efficient solver for symmetric positive definite (SPD) systems arising from elliptic and parabolic PDEs, while nonsymmetric systems from hyperbolic PDEs remain a significant challenge. This dissertation develops AMG methods and theory for nonsymmetric problems. First, we develop a novel approach combining mode constraints from energy-minimization AMG with local approximations of ideal restriction in $\ell$AIR, resulting in constrained $\ell$AIR (C$\ell$AIR), which demonstrates scalable convergence across advective and diffusive problems. Second, we extend optimal AMG theory by deriving spectral radius estimates for the two-grid error transfer operator using matrix-induced orthogonality, enabling convergence predictions for …
Minimal Error Functions On Irregular Subsets Of The Real Line, Robert Michael Dukes
Minimal Error Functions On Irregular Subsets Of The Real Line, Robert Michael Dukes
Mathematics & Statistics ETDs
Chebyshev Polynomials, those that minimize the maximal error on a compact set, are one of the most practical tools for approximating smooth functions. The classical results are on the set [-1, 1]; in this paper, we extend to more complicated subsets of the real line. We demonstrate some classical results and then take the result from [2] on regular Parreau-Widom Sets and extend it to semi-regular sets, defined as sets whose regular part is closed. We introduce the Regularity Coefficient as a series formed by evaluating the Green’s Function at irregular points. This new machinery is applied to the lower …
Derivation Of Adjoint Based Error Estimates For Nonlinear Ordinary Differential Equations With Application To Multistage Sir Models With Demographics, Daniel Alcala
Mathematics & Statistics ETDs
Ordinary Differential Equations (ODEs) are central to the mathematical modeling of various real-world phenomena, from mechanical systems governed by Newton’s laws to epidemic dynamics described by SIR-type ODEs. Since many ODEs do not admit closed-form analytic solutions, we approximate them numerically (e.g., with Euler’s, Runge–Kutta, or other such methods). This raises the key question: How accurate are these numerical solutions? In particular, reliably estimating the error in some quantity of interest (QoI) at time T without having an exact solution is of great scientific interest.
The first main contribution of this thesis is the development and analysis of adjoint-based error …
Toward Simulating 2d Cell Surfaces In A Disk, Myriam Allred
Toward Simulating 2d Cell Surfaces In A Disk, Myriam Allred
Mathematics & Statistics ETDs
Certain evolution models of cell surfaces (treated in two-dimensions) involve the solution of the Helmholtz equation with jump conditions enforced on an immersed closed curve. This thesis presents a sparse, modal spectral method for solving such Helmholtz problems. The solution is required to be continuous across the curve, but with a jump discontinuity in the normal derivative proportional to the planar curvature. The method relies on classical Fourier-Chebyshev basis functions, with the application of modal Chebyshev integration matrices to achieve sparse, banded approximations of the Helmholtz equation. The method achieves spectral convergence, despite the inherent low regularity of the relevant …
Quasistatic Peridynamics, Existence Of Unique Solution In The Presence Of Damage, Nuwanthi N. Samarawickrama
Quasistatic Peridynamics, Existence Of Unique Solution In The Presence Of Damage, Nuwanthi N. Samarawickrama
LSU Doctoral Dissertations
A mathematical model for damage propagation based on nonlocal potentials is developed within the framework of peridynamics. This model is applied to simulate damage evolution in cyclically loaded structures. By neglecting inertial effects, a well-posed quasistatic formulation for cyclic loading is obtained.\\ The resulting equation is expressed as a nonlocal and nonlinear integral operator that couples damage evolution to the deformation field.\\ This coupling occurs through the product of a damage factor and the derivative of a force potential. The damage factor ranges between zero and one, where one represents undamaged material and zero indicates complete damage.\\ It serves to …
Gain Threshold Optimization Using Fano Resonance, Alina Oktiabrskaia
Gain Threshold Optimization Using Fano Resonance, Alina Oktiabrskaia
LSU Doctoral Dissertations
The study of resonances in electromagnetics plays a critical role in the design of optical systems. This dissertation investigates the interaction between resonance and gain in optical structures to establish a universal principle for achieving ultra-low-threshold lasing. Through the analysis of geometric symmetries, material properties, and coupling mechanisms, this research develops prototype structures applicable to a wide range of optical and electromagnetic systems. A range of models is considered, starting from a simple onedimensional string-resonator system (based on the model of H. Lamb), then advancing to two- and three-dimensional waveguide models, and culminating with a realistic high-contrast model in open …
Applications Of Contracting Self-Similar Groups To Cryptography And Scale Groups, Arsalan Akram Malik
Applications Of Contracting Self-Similar Groups To Cryptography And Scale Groups, Arsalan Akram Malik
USF Tampa Graduate Theses and Dissertations
Given their peculiar properties, self-similar groups are of great interest both from applications and theoretical standpoints. In this work we study the scope of their applications in post-quantum cryptography and in constructing scale groups via lifting maps.
We propose self-similar contracting groups as a platform for cryptographic schemes based on simultaneous conjugacy search problem (SCSP). This class of groups admits fast polynomial-time algorithms for the word problem and element multiplication that can be used for effective encryption and decryption of messages. It contains extraordinary examples like the Grigorchuk group, which is known to be non-linear, thus making some of existing …
Notes On The Invariance Of Tautness Under Lie Sphere Transformations, Thomas E. Cecil
Notes On The Invariance Of Tautness Under Lie Sphere Transformations, Thomas E. Cecil
Mathematics and Computer Science Department Faculty Scholarship
An embedding ϕ : V → Sn of a compact, connected manifold V into the unit sphere Sn ⊂ Rn+1 is said to be taut, if every nondegenerate spherical distance function dp, p ∈ Sn, is a perfect Morse function on V , i.e., it has the minimum number of critical points on V required by the Morse inequalities. In these notes, we give an exposition of the proof of the invariance of tautness under Lie sphere transformations due to ´Alvarez Paiva. First we extend the definition of tautness of submanifolds of S …
The Other Side Of The Equation: De-Simplification, A Prerequisite For Calculus, Stephen L. Brown
The Other Side Of The Equation: De-Simplification, A Prerequisite For Calculus, Stephen L. Brown
ACMS Conference Proceedings 2005
No abstract provided.
Property Testing Ai: An Efficient Frontier, Paul Sopher Lintilhac
Property Testing Ai: An Efficient Frontier, Paul Sopher Lintilhac
Dartmouth College Ph.D Dissertations
In this dissertation, we take a step towards addressing the major problem of a lack of standardized and rigorous approaches to testing and evaluation of AI systems. Taking inspiration from both the fields of Property Testing and Property Based Testing (for programs), we develop a novel taxonomy of partially overlapping classes of properties of AI systems, including simple properties, compound properties, higher order properties, data relation properties, and architecture-utility properties. We argue that this taxonomy categorizes a diverse set of AI traits -- including accuracy, fairness, robustness, monotonicity, point-wise and global privacy properties, sensitivity, and more -- according to the …
Stability Insights From Modeling Chronic Myelogenous Leukemia, Giovani Thai
Stability Insights From Modeling Chronic Myelogenous Leukemia, Giovani Thai
Master's Theses
This thesis centers around a model for chronic myelogenous leukemia (CML) as it behaves under imatinib treatment, a common medication for CML patients, and the anti-leukemia immune response. The dynamics are represented with a system of nonlinear delay-differential equations first constructed by Kim et al. in 2008, capturing population changes of T-cells and various CML growth stages. We investigate stability in both the clinical and mathematical sense. Through numerical simulations, we computationally incorporate a supplementary treatment plan to determine its effectiveness in aiding immune response and medication in achieving remission and full elimination. The primary goal is to conduct a …