Physical Sciences and Mathematics Commons^™

Remediation Strategies For Mercury Contaminated Lakes And Reservoirs Within The State Of California, Emily Chortek

Master's Projects and Capstones

Mercury is an environmental and public health concern due to its neurodegenerative effects and ubiquitous concentration within the environment. To mitigate these risks and reduce concentrations within the environment, remediation methods are necessary. The purpose of this paper is to investigate and evaluate the efficacy of a number of remediation options for mercury contaminated lakes and reservoirs in the State of California. This paper also identifies a number of challenges associated with the implementation of each method and provides recommendations for environmental managers to use when remediating mercury contaminated lakes. Hypolimnetic oxygenation (HOS) was found to be the least problematic …

The Future Of Nuclear Security: A Medical Physicist’S Perspective, Katharine E. Thomson

International Journal of Nuclear Security

Planning for the future of nuclear security is a vital and complex task, requiring cooperation and contribution from many disciplines and industries. This diversity of expertise should include the medical sector, which faces many of the same challenges as the nuclear industry: controlling access to dangerous material, creating a strong security culture, cooperating with the wider world and engaging the public.

Medical physicists, of which the author is one, oversee all aspects of small-scale radiation use. This paper discusses three key areas increasingly important to both medical and nuclear uses of radioactive materials: public engagement, prevention of nuclear and radiological …

The Future Of Nuclear Security In Moroccan Territory After The Creation Of The New Moroccan Agency Of Nuclear And Radiological Safety And Security: Opportunities And Challenges, Amal Touarsi, Amina Kharchaf

International Journal of Nuclear Security

Nowadays, a security regime for protecting nuclear and radiological material—providing an intelligent national regulatory institution and establishing national security laws—is necessary in order for a state to ensure security of nuclear and radiological materials used within its borders.

This paper focuses on discussing the opportunities and challenges facing the future of nuclear security after the creation of the new Moroccan Agency of Nuclear and Radiological Safety and Security.

Fluoroethoxy-1,4-Diphenethylpiperidine And Piperazine Derivatives: Potent And Selective Inhibitors Of [3H]Dopamine Uptake At The Vesicular Monoamine Transporter-2, Emily R. Hankosky, Shyam R. Joolakanti, Justin R. Nickell, Venumadhav Janganati, Linda P. Dwoskin, Peter A. Crooks

Pharmaceutical Sciences Faculty Publications

A small library of fluoroethoxy-1,4-diphenethyl piperidine and fluoroethoxy-1,4-diphenethyl piperazine derivatives were designed, synthesized and evaluated for their ability to inhibit [³H]dopamine (DA) uptake at the vesicular monoamine transporter-2 (VMAT2) and dopamine transporter (DAT), [³H]serotonin (5-HT) uptake at the serotonin transporter (SERT), and [³H]dofetilide binding at the human-ether-a-go-go-related gene (hERG) channel. The majority of the compounds exhibited potent inhibition of [³H]DA uptake at VMAT2, with Ki values in the nanomolar range (K_i = 0.014–0.073 μM). Compound 15d exhibited the highest affinity (K_i = 0.014 μM) at VMAT2, and had 160-, 5-, …

Effect Of An 860-M Thick, Cold, Freshwater Aquifer On Geothermal Potential Along The Axis Of The Eastern Snake River Plain, Idaho, Thomas E. Lachmar, Thomas G. Freeman, Christopher J. Sant, Jeffrey R. Walker, Joseph F. Batir, John W. Shervais, James P. Evans, Dennis L. Nielson, David D. Blackwell

Geosciences Faculty Publications

A 1912-m exploration corehole was drilled along the axis of the eastern Snake River Plain, Idaho. Two temperature logs run on the corehole display an obvious inflection point at about 960 m. Such behavior is indicative of downward fluid flow in the wellbore. The geothermal gradient above 935 m is 4.5 °C/km, while the gradient is 72–75 °C/km from 980 to 1440 m. Projecting the higher gradients upward to where they intersect the lower gradient on the temperature logs places the bottom of the cold, freshwater Snake River Plain aquifer, which suppresses the geothermal gradient at this location, at least …

New Implementations For Tabulating Pseudoprimes And Liars, Wuyang Liu

Honors Projects

Whether it is applied to primality test or cryptography, pseudoprimes are one of the most important topics in number theory. Regarding the study of strong pseudoprimes, there are two problems which mathematicians have been working on:
1. Given a, b, find all a-spsp up to b.
2. Given an odd composite n, find all a -n such that n is an a-spsp.
where n = a-spsp means n is a strong pseudoprime to base a, and a is a strong liar of n.

The two problems are respectively referred to as …

Repairing Gaps In Kinari-2 For Large Scale Protein And Flexibility Analysis Applications, Magdalena Metlicka, Mojtaba Nouri Bygi, Ileana Streinu

Computer Science: Faculty Publications

Pebble game rigidity analysis is a combinatorial method, implemented in our free web server KinariWeb, for extracting protein rigidity and flexibility information without performing costly molecular dynamics simulations. Due to the idiosynchrasies of the data in the Protein Data Bank (PDB), Kinari succeeds only on a fraction of the available files. Motivated by large scale applications, aiming at processing almost all the PDB files, we have recently developed a faster and more robust version, the phased pebble game algorithm. It is specifically designed to take advantage of the sequential structure of biopolymers. However, the structural data available in the Protein …

Environmental Ngo-Private Sector Partnerships: A Tool To Generate Business Value And Protect The Natural World, Carolyn Nogy Nogy

Master's Projects and Capstones

Many environmental challenges are complicated by complex and social, cultural, economic and political interactions, which are difficult to address by a single entity. However, partnerships can offer the necessary depth and versatility to address them effectively. By working together, there is an opportunity for cross sector partners to leverage their unique expertise, while blending resources to achieve more comprehensive and sustainable solutions to existing environmental problems. This project examines the use of partnerships between environmental NGOs and the private sector to manage complex environmental problems, providing a critical assessment of the partnership attributes that generate the most mutual benefit. The …

Assessing And Enhancing Nuclear Safety And Security Culture For Small Facilities That Handle Radioactive Material, Solymosi Máté

International Journal of Nuclear Security

The use of radioactive sources is expanding all over the world and abreast the necessity of the enhancement of its safe and secure application is increasing too. In the nuclear industry, the safety and security are top priorities since decades. They share the same goal, to protect humans from the negative affect of the ionizing radiation. The human component of them is a significant factor and technical solutions can protect us so far and thus the culture for safety and security become a major focus. On the other hand, there are still some contradiction between recommendations and international guidance of …

Can Addressing Language Skills For Fifth Grade Ells In A Multiplication Curriculum Help Address The Achievement Gap In Math? A Multiplication Workbook For Big Kids, Michelle Douglas

Master's Projects and Capstones

Currently, the state of California has 1,332,405 students from grades k-12 who speak a language other than English at home (Caledfacts, 2016). When I started my first year teaching fifth grade with 95% of my students being English language learners (ELLs), I was surprised to see an achievement gap of two to three years in my student’s reading and math skills. I found that my student’s developmental language and math skills contributed to a lack of engagement during math time. Upon further research, I found that these three factors play a role in the wide achievement gaps between ELLs and …

Relativistic Three-Dimensional Lippman-Schwinger Cross Sections For Space Radiation Applications, Charles M. Werneth, Xiaojing Xu, Ryan B. Norman, Khin M. Maung

Faculty Publications

Radiation transport codes require accurate nuclear cross sections to compute particle fluences inside shielding materials. The Tripathi semi-empirical reaction cross section, which includes over 60 parameters tuned to nucleon-nucleus (NA) and nucleus-nucleus (AA) data, has been used in many of the world’s best-known transport codes. Although this parameterization fits well to reaction cross section data, the predictive capability of any parameterization is questionable when it is used beyond the range of the data to which it was tuned. Using uncertainty analysis, it is shown that a relativistic three-dimensional Lippmann-Schwinger (LS3D) equation model based on Multiple Scattering Theory (MST) that uses …

New Ventures In Amidine-Based Catalyst Design, Nicholas Alan Ahlemeyer

Arts & Sciences Graduate Student Theses and Dissertations

Two new cascade transformations of α,β-unsaturated thioesters catalyzed by amidine-based catalysts have been developed. First, a reagent-free transformation of o-formylaryl cinnamoyl thioesters catalyzed by HBTM-2 to produce 2-substituted thiochromenes achieved high enantioselectivities and yields while forming carbon dioxide as the only byproduct. Second, a highly diastereo- and enantioselective tandem rearrangement of less reactive enone thioesters into tricyclic thiochromanes in the presence of electron-rich amidine-based catalysts was developed. These catalysts were designed with the help of DFT calculations. H-PIP, the first chiral amidine-based catalyst synthesized in our group, performed the best overall in the thiochromane synthesis.The second chapter of this thesis …

Untangling The Mechanics Of Co-Entangled Cytoskeletal Networks, Shea Ricketts

Undergraduate Honors Theses

Active networks of interlinked protein filaments comprising the cytoskeleton largely control cellular mechanics and cell architecture. By forming cytoskeleton networks that combine motile, semiflexible actin with rigid, supportive microtubules, cells maintain structural integrity and shape while being able to flow and move. To elucidate the complex mechanical processes that arise between interacting networks of actin and microtubules within cells, we create a suite of randomly-oriented, well mixed networks of actin and microtubules by co-polymerizing varying ratios of both proteins in situ. We use optical tweezer microrheology in order to characterize the nonlinear mesoscale mechanics of in vitro co-entangled actin-microtubule composites. …

Boulder Distribution Analysis Of Impact Craters In The Tharsis Region And Elysium Planitia, Mars, Nicole Button

LSU Master's Theses

Crater counting is an accepted method for dating the surface of a planetary body. An older landscape will have a higher areal density of craters due to exposure of impacts occurring over a longer time period. Since each initial impact only forms one primary crater, secondary craters need to be excluded in the crater counting method to appropriately catalog only distinct impact events. However, small primary craters may be difficult to distinguish from secondary craters. Understanding physical features of impact craters, such as the ejecta blanket, would improve the planetary community’s ability to differentiate between the two types of craters. …

Tensorviz: Visualizing The Training Of Convolutional Neural Network Using Paraview, Xinyu Chen, Qiang Guan, Xin Liang, Li-Ta Lo, Simon Su, Trilce Estrada, James Ahrens

Computer Science Faculty Research & Creative Works

Deep Convolutional Networks have been very successful in visual recognition tasks recently. Previous works visualize learned features at different layers o help people to understand how CNNs learn visual recognition tasks. However they do not help to accelerate the training process. We use Paraview to provides both qualitative and quantitative visualization that help understand the learning procedure, tune the learning parameters and direct merging and pruning of neural networks.

Tensorviz: Visualizing The Training Of Convolutional Neural Network Using Paraview (Poster), Xinyu Chen, Qiang Guan, Xin Liang, Li-Ta Lo, Simon Su, Trilce Estrada, James Ahrens

Computer Science Faculty Research & Creative Works

Deep Convolutional Networks have been very successful in visual recognition tasks recently. Lots of previous works aimed to help people to get senses of why those biology-inspired networks achieved such good performances. Deconvnet[1], Guided propagation[2] and a comprehensive visualization tool box[3] can help people to see features learned at different layers of the networks. These works in some extent provided understanding and support for the biology origin of how convolutional networks emulate visual recognition tasks. However, due to the complexity of searching in very high dimensional parameter space, the whole training remains in black-boxes. Normally a large network needs weeks …

Breadcrumbs: Privacy As A Privilege, Prachi Bhardwaj

Capstones

Breadcrumbs: Privacy as a Privilege Abstract

By: Prachi Bhardwaj

In 2017, the world saw more data breaches than in any year prior. The count was more than the all-time high record in 2016, which was 40 percent more than the year before that.

That’s because consumer data is incredibly valuable today. In the last three decades, data storage has gone from being stored physically to being stored almost entirely digitally, which means consumer data is more accessible and applicable to business strategies. As a result, companies are gathering data in ways previously unknown to the average consumer, and hackers are …

A Spatio-Temporal Approach To Mitigate Automotive Radar Spoofing Attacks, Prateek Kapoor

Graduate Dissertations and Theses

Cyber-physical system (CPS) has become an integral part of human life, ranging from aircraft to health care systems. The security of these critical components ensures its wider acceptability. Traditionally, many works to secure cyber-physical system (CPS) has been done in the cyber domain, like securing inter/intra CPS communication, securing the exposed software, rebuilding control input derived from sensor data post-digitization, using sensor fusion. All of this security software suffers from a basic attack wherein an attacker compromises the physical/analog sensing system. Researchers have made some progress in mitigating such attacks on physical/analog signals of CPS, the current state of the …

Best Practices For Test Driven Development, Timothy Tacker

All Student Theses and Dissertations

In his award-winning book, Test-driven Development By Example, Kent Beck wrote, "Clean code that works...is the goal of Test-driven Development (TDD)." TDD is a style of software development that first begins with the creation of tests and then makes use short, iterative development cycles until all test requirements are fulfilled. In order to provide the reader with sufficient background to understand the concepts discussed, this thesis begins by presenting a detailed description of this style of development. TDD is then contrasted with other popular styles, with a focus toward highlighting the many benefits this style offers over the others. This …

Hazmat Storage Near Nyc Waterways Endangers Communities, Brett E. Dahlberg, Nicole Acevedo

Capstones

New York City has 520 miles of shoreline--that’s more than Miami and Los Angeles combined. These waterfronts are home to some of the city’s most polluted sites because major part of it is zoned for industrial use. Dozens of industrial plants in this area store toxic chemicals in flood zones: substances that are hazardous to our health, like Benzene, which is used in rocket fuel, toluene, a paint thinner, and lead a neurotoxin. In a flood, these chemicals can easily get caught up in moving waters and pollute entire neighborhoods.

That’s exactly what happened when Hurricane Sandy hit in 2012. …

System Characterizations And Optimized Reconstruction Methods For Novel X-Ray Imaging, Huifeng Guan

McKelvey School of Engineering Graduate Student Theses & Dissertations

In the past decade there have been many new emerging X-ray based imaging technologies developed for different diagnostic purposes or imaging tasks. However, there exist one or more specific problems that prevent them from being effectively or efficiently employed. In this dissertation, four different novel X-ray based imaging technologies are discussed, including propagation-based phase-contrast (PB-XPC) tomosynthesis, differential X-ray phase-contrast tomography (D-XPCT), projection-based dual-energy computed radiography (DECR), and tetrahedron beam computed tomography (TBCT). System characteristics are analyzed or optimized reconstruction methods are proposed for these imaging modalities. In the first part, we investigated the unique properties of propagation-based phase-contrast imaging technique …

Planning Cities, Economically Or Communally: A Comparative Study Of Amsterdam And San Francisco, Raina Dawn Whittekiend

Master's Theses

Globalization has spun “community” off its axis. What once defined community is no longer the current state of the community. Increased economic transactions have led to the instability of communities that once depended on one another at the local level. These communities are now dependent on systems that do not know nor understand their actors. This lack of relationship between development and subject is witnessed and highly scrutinized in developing countries all over the world and has been intensely researched in academic literature. This thesis intends to better understand why in modernized global cities these same processes of development and …

Locality-Aware Concurrency Platforms, Jordyn Chrystopher Raymond Maglalang

McKelvey School of Engineering Graduate Student Theses & Dissertations

Modern computing systems from all domains are becoming increasingly more parallel. Manufacturers are taking advantage of the increasing number of available transistors by packaging more and more computing resources together on a single chip or within a single system. These platforms generally contain many levels of private and shared caches in addition to physically distributed main memory. Therefore, some memory is more expensive to access than other and high-performance software must consider memory locality as one of the first level considerations.

Memory locality is often difficult for application developers to consider directly, however, since many of these NUMA affects are …

Accurate Determination And Application Of Local Strain For Studying Tissues With Gradients In Mechanical Properties, John Boyle

McKelvey School of Engineering Graduate Student Theses & Dissertations

Determination of the mechanical behavior of materials requires an understanding of deformation during loading. While this is traditionally accomplished in engineering by examining a force displacement curve for a whole sample, these techniques implicitly ignore local geometric complexities and local material inhomogeneities commonly found in biologic tissues. Techniques such as normalized cross correlation have been classically applied to address this issue and resolve deformation at the local level; however, these techniques have proven unreliable when deformations become large, if the sample undergoes a rotation, and/or if strain fields become incompatible (e.g. at or near failure).

Presented here is a toolbox …

Multiscale Imaging Of The Mouse Cortex Using Two-Photon Microscopy And Wide-Field Illumination, Jonathan Richard Bumstead

McKelvey School of Engineering Graduate Student Theses & Dissertations

The mouse brain can be studied over vast spatial scales ranging from microscopic imaging of single neurons to macroscopic measurements of hemodynamics acquired over the majority of the mouse cortex. However, most neuroimaging modalities are limited by a fundamental trade-off between the spatial resolution and the field-of-view (FOV) over which the brain can be imaged, making it difficult to fully understand the functional and structural architecture of the healthy mouse brain and its disruption in disease. My dissertation has focused on developing multiscale optical systems capable of imaging the mouse brain at both microscopic and mesoscopic spatial scales, specifically addressing …

Two-Component Hydrogel As Biomimetic Vitreous Substitutes, Sruthi Santhanam

McKelvey School of Engineering Graduate Student Theses & Dissertations

The vitreous humor of the eye is a biological hydrogel principally composed of fibrillary collagen interspersed with semi-flexible polyelectrolyte, hyaluronic acid (HA). Certain pathological conditions necessitate its removal and replacement. Current vitreous substitutes, such as silicone oils and perfluorocarbons, are hydrophobic, do not resemble the properties of the vitreous, and have known complications. An ideal vitreous substitute should have properties of the natural vitreous, perform its functions, and be biocompatible in the eye. Inspired by the structure and composition of the natural vitreous, we used bio-mimicry to develop an injectable two-component hydrogel. The hydrogel is composed of a fibrillary gellan, …

System Optimization And Iterative Image Reconstruction In Photoacoustic Computed Tomography For Breast Imaging, Yang Lou

McKelvey School of Engineering Graduate Student Theses & Dissertations

Photoacoustic computed tomography(PACT), also known as optoacoustic tomography (OAT), is an emerging imaging technique that has developed rapidly in recent years. The combination of the high optical contrast and the high acoustic resolution of this hybrid imaging technique makes it a promising candidate for human breast imaging, where conventional imaging techniques including X-ray mammography, B-mode ultrasound, and MRI suffer from low contrast, low specificity for certain breast types, and additional risks related to ionizing radiation. Though significant works have been done to push the frontier of PACT breast imaging, it is still challenging to successfully build a PACT breast imaging …

Abiotic- And Biotic-Formation Of Manganese Oxides And Their Fate In Environmental Systems, Haesung Jung

McKelvey School of Engineering Graduate Student Theses & Dissertations

Manganese (hydr)oxide (Mn (hydr)oxide) minerals are ubiquitous in aquatic and terrestrial environments. These minerals have high surface areas and are highly sorptive and redox active. From decades of accumulated knowledge about natural redox cycling, we have found that Mn (hydr)oxides play critical roles as electron donors and acceptors in elemental geochemical cycling and biological metabolisms in nature. Thus, Mn (hydr)oxides have garnered increasing interest to understand natural systems. Considering the variety of redox reactions with Mn (hydr)oxides in nature, it is also expected that there should be diverse pathways to form Mn (hydr)oxides through abiotic and biotic processes. Previous studies …

Probing Consciousness, Samia Bouzid

Capstones

For centuries, the study of consciousness remained the purview of philosophers, spiritualists and religious leaders. But in the 1980s, the co-discoverer of the double-helix, James Crick, initiated a quest for a scientific explanation for consciousness — in a secret club. In the decades that followed, consciousness gained ground as a respectable area of scientific study, in fields such as neuroscience, artificial intelligence and physics. Yet, the more scientists learn about consciousness, the more it calls into question our fundamental assumptions about the way the world works. https://samiabouzid.atavist.com/probing-consciousness

Repairing Gaps In Kinari-2 For Large Scale Protein And Flexibility Analysis Applications, Magdalena Metlicka, Mojtaba Nouri Bygi, Ileana Streinu

Computer Science: Faculty Publications

Pebble game rigidity analysis is a combinatorial method, implemented in our free web server KinariWeb, for extracting protein rigidity and flexibility information without performing costly molecular dynamics simulations. Due to the idiosynchrasies of the data in the Protein Data Bank (PDB), Kinari succeeds only on a fraction of the available files. Motivated by large scale applications, aiming at processing almost all the PDB files, we have recently developed a faster and more robust version, the phased pebble game algorithm. It is specifically designed to take advantage of the sequential structure of biopolymers. However, the structural data available in the Protein …