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Physical Sciences and Mathematics Commons™

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2017

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Articles 11101 - 11102 of 11102

Full-Text Articles in Physical Sciences and Mathematics

The Anticancer Effects Of The Different Analogs Of Cysteine Deleted Tachyplesin On A549 Lung Cancer Cells, Nathan Riley Hendrickson Jan 2017

The Anticancer Effects Of The Different Analogs Of Cysteine Deleted Tachyplesin On A549 Lung Cancer Cells, Nathan Riley Hendrickson

Master's Theses and Doctoral Dissertations

It has been previously shown that cysteine-deleted tachyplesin (CDT) and its many analogs display antibacterial effects. However, little has been said about its possible anticancer effects and which analogs serve as the best inhibitors of the growing cancer cells. This research focused on CDT and four of its analogs: All D-CDT, Reverse DCDT, Reverse CDT, and Serine-Control CDT. MTT assays against the A549 adenocarcinoma lung cancer cell line showed All D-CDT to be the most effective analog in preventing cancer cell growth. Hyaluronidase and apoptosis assays were performed to better understand the mechanism by which the All D-CDT is preventing …


Assessing Patient And Caregiver Intent To Use Mobile Device Videoconferencing For Remote Mechanically-Ventilated Patient Management, Brian R. Smith Jan 2017

Assessing Patient And Caregiver Intent To Use Mobile Device Videoconferencing For Remote Mechanically-Ventilated Patient Management, Brian R. Smith

Master's Theses and Doctoral Dissertations

The Michigan Medicine adult Assisted Ventilation Clinic (AVC) supports patients with neuromuscular disorders and spinal cord injuries and their caregivers at home, helping them avoid expensive emergency department visits, hospitalization, and unnecessary or excessive treatments. Mobile device videoconferencing provides an effective capability for remote mechanically-ventilated patient management but must rely upon an unknown infrastructure comprising patient and caregiver mobile device ownership, connectivity, and experience—and intent to use the service if provided. The purpose of this study was to measure the extent of this infrastructure and the perceived ease of use, perceived usefulness, and intent to use this mobile device …