Physical Sciences and Mathematics Commons^™

Efficient Partitioning And Allocation Of Data For Workflow Compositions, Annamaria Victoria Kish

Theses and Dissertations

Our aim is to provide efficient partitioning and allocation of data for web service compositions. Web service compositions are represented as partial order database transactions. We accommodate a variety of transaction types, such as read-only and write-oriented transactions, to support workloads in cloud environments. We introduce an approach that partitions and allocates small units of data, called micropartitions, to multiple database nodes. Each database node stores only the data needed to support a specific workload. Transactions are routed directly to the appropriate data nodes. Our approach guarantees serializability and efficient execution.

In Phase 1, we cluster transactions based on data …

Modern Estimation Problems In Group Testing, Md Shamim Sarker

Theses and Dissertations

In the simplest form of group testing, pools are formed by compositing a fixed number of individual specimens (e.g., blood, urine, swab, etc.) and then the pools are tested for a binary characteristic, such as presence or absence of a disease. Group testing is commonly used to screen for a variety of sexually transmitted diseases in epidemiological applications where the main goal is to increase testing efficiency. In this dissertation, we study three estimation problems that are motivated by real-life applications. We propose new methods to model group testing data for both single and multiple infections. In the first problem, …

Semiparametric Joint Dynamic Modeling Of A Longitudinal Marker, Recurrent Competing Risks, And A Terminal Event, Piaomu Liu

Theses and Dissertations

The joint modeling framework has found extensive applications in cancer and other biomedical research. For example, recent initiatives and developments in precision medicine call for appropriate prognostic tools to assist individualized or personalized approaches in cancer diagnosis and treatment. Data generated by clinical trials and medical research often include correlated longitudinal marker measurements and time- to-event information, which are possibly a recurrent event, competing risks, and a survival outcome. Primary interests of joint modeling include the association between the longitudinal marker measurements and time-to-event data, as well as predictions of survival probabilities of new observational units from the same population. …

Estimation Of The Quantum Effects Of Nuclei In Large Molecular Systems, Bing Gu

Theses and Dissertations

Chemical dynamics, in principle, should be understood by solving the time-dependent Schrödinger equation for a molecular system, describing motion of the nuclei and electrons. However, the computational efforts to solve this partial second-order differential equation scales exponentially with the system size, which prevents us from getting exact numerical solutions for systems larger than 4-5 atoms. Thus, approximations simplifying the picture are necessary. The so-called Born-Oppenheimer approximation, separating motion of the electrons and nuclei is the central one: solution to the electronic Schrödinger equation defines the potential energy surface on which the nuclear motion unfolds, and there are standard quantum chemistry …

Spatio-Temporal Analysis Of The Occupational Fatal Victimization Of Law Enforcement Officers In The Us, Xueyi Xing

Theses and Dissertations

The models with constant coefficients of the covariates across space and time are commonly used in spatio-temporal analyses. However, the associations between risk factors and the outcome could have locally differential temporal trends in many cases. In this study, a Bayesian latent cluster modeling strategy is employed to identify potential spatial clusters in which locally specific sets of temporally varying coefficients of covariates are allowed. A state-level panel data of police officers occupational fatal victimization for the years 1979-2010 is used. To accommodate overdisperson and excess zeros, a negative binomial model and zero-inflated Poisson/negative binomial models are also utilized. A …

Investigating Cross Talk Between The High And Low Iron Sensors In Saccharomyces Cerevisiae, John S. Hepburn

Theses and Dissertations

Iron is essential for nearly all life on earth. Cells must maintain sufficient levels of this important nutrient due its function as a central co-factor for many cellular processes. Although iron is extremely plentiful, its poor solubility requires specialized import. On the other side, too much iron inside the cell can lead to the generation of reactive oxygen species (ROS), which have deleterious effects on many cellular functions and have been implicated in a wide variety of diseases such as cancer and Alzheimer’s disease. Using the model eukaryote Saccharomyces cerevisiae, or budding yeast, our research group has accomplished much in …

Mechanistic Investigation And Potential Application Of A Fatty Acid Decarboxylating Cytochrome P450 Peroxygenase, Chun H. Hsieh

Theses and Dissertations

OleT (CYP152L1) is a recently discovered cytochrome P450 that is structurally similar to peroxide dependent P450s that catalyze fatty acid hydroxylations. OleT has been shown to catalyze the cleavage of n chain length fatty acids to form n-1 alkenes through C-C bond scission of the terminal carboxylate. Using headspace GC-MS and FTIR with isotopically labeled substrates, we have confirmed that OleT metabolizes eicosanoic acid to 1-nonadecene, forming carbon dioxide (CO2) as a co-product of the reaction. No oxygen deriving from peroxide is observed in either product. In order to probe the mechanistic deviation of OleT from P450 peroxygenases, we have …

Regression Models For Count Data Based On The Double Poisson Distribution, Rebecca Wardrop

Theses and Dissertations

This paper explores the double Poisson distribution. The probability mass function and the difficulties associated with derivative-based optimization for this distribution are discussed. Stata software developed for estimation of double Poisson regression is detailed. Simulations are used to test the software. Data which are over-, under-, and equidispersed relative to the Poisson are generated and the software is utilized to estimate a regression model, a zero-inflated model, and a marginalized zero-inflated model all based on the double Poisson distribution. The estimated power of the test for φ = 1 for the double Poisson models are compared to the power of …

An Efficient Method For Optimizing Segmentation Parameters, Jacob D' Avy, Wei-Wen Hsu, Chung-Hao Chen, Andreas F. Koschan, Mongi Abidi

Electrical & Computer Engineering Faculty Publications

Segmenting an image into meaningful regions is an important step in many computer vision applications such as facial recognition, target tracking and medical image analysis. Because image segmentation is an ill-posed problem, parameters are needed to constrain the solution to one that is suitable for a given application. For a user, setting parameter values is often unintuitive. We present a method for automating segmentation parameter selection using an efficient search method to optimize a segmentation objective function. Efficiency is improved by utilizing prior knowledge about the relationship between a segmentation parameter and the objective function terms. An adaptive sampling of …

Materials Discovery By Crystal Growth: Synthesis, Structure Determination, Magnetic, And Optical Properties Of Complex Lanthanide Containing Oxides, Oxyhydroxides, And Oxyfluorides, Allison Marie Latshaw

Theses and Dissertations

Exploratory crystal growth is a versatile technique and one that can advance materials discovery. Through exploratory crystal growth, it is possible to synthesize many new materials that can have applications in many fields, including solid-state lighting. There exist many adaptations for exploratory crystal growth, including the use of alkali halide flux growth and hydroflux growth, both reported herein. By changing variants in these techniques like reactant ratios, temperature, reaction profile, and, most importantly here, the flux compositions, it is possible to change the products formed or fine tune reactions for product purity.

For solid-state lighting applications, compounds that adopt colorless …

Measurements Of Electrostatic Double Layer Potentials With Atomic Force Microscopy, Jason Giamberardino

Theses and Dissertations

The aim of this thesis is to provide a thorough description of the development of theory and experiment pertaining to the electrostatic double layer (EDL) in aqueous electrolytic systems. The EDL is an important physical element of many systems and its behavior has been of interest to scientists for many decades. Because many areas of science and engineering move to test, build, and understand systems at smaller and smaller scales, this work focuses on nanoscopic experimental investigations of the EDL. In that vein, atomic force microscopy (AFM) will be introduced and discussed as a tool for making high spatial resolution …

Development Of Reactions And Methods For Labeling Biomolecules In Cells, Enoch Agbesi Adogla

Theses and Dissertations

The complexity of cellular environments presents a challenge to efforts at studying and elucidating biomolecules in cells. Covalent ligation of biomolecules with fluorescent molecules that have a reactive functional group that can react with a complementary functional group on biomolecules is one way that has been utilized to study biomolecules. It enables visualization and tracking of ligation and transportation of molecules within the cell. However, the myriad of functional groups within the cell makes achieving selectivity difficult. To circumvent this problem, reactions that do not interfere with biology have been developed. These reactions, referred to as bioorthogonal reactions must be …

Novel Approaches To Investigate The Oxidation Rate Of Fe(Ii) And The Role Of Fe(Ii)/Fe(Iii) Cycling On The Maintenance Of Reactive Oxygen Species In Aquatic Systems, Justin Maurice Copeland

Theses and Dissertations

The biogeochemical cycling of iron, oxygen, and organic carbon are inextricably linked through the intermediacy of Reactive Oxygen Species (ROS) brought about by the autoxidation of ferrous iron (Fe(II)). This dissertation presents laboratory and field-based studies to investigate the kinetics of Fe(II) oxidation and its role in the production of ROS at oxic/anoxic interfaces. The net oxidation of Fe(II) in natural waters is a complex process consisting of alternating cycles of Fe(II) oxidation and Fe(III) reduction processes that are ultimately terminated via precipitation as insoluble Fe(III) (oxy)hydroxides. This complicates kinetic measurements of individual reaction steps in the process.

A critical …

Cobaltocenium Containing Polymers: Complexation With Organic Anion And Initial Assesment For Anion Exchange Membranes, Mohammad Pabel Kabir

Theses and Dissertations

In this thesis, cobaltocenium containing monomers and polymers are investigated for guest anion loading and alkaline anion exchange membrane for fuel cells. The properties of these polymers are characterized and discussed.

Chapter 1 describes overall background and potential applications of metallocene and metallocenium containing polymers. The research objectives of metallocenium containing polymers are discussed.

Cobaltocenium containing polymers have potential applications in biomedical science. Therefore, the effect of different parameters such as electrostatic charge, size, conformation, π-electron system and hydrogen bonding on the interactions between these polymers and small anionic probes has been studied qualitatively, as described in Chapter 2. A …

Score Test Derivations And Implementations For Bivariate Probability Mass And Density Functions With An Application To Copula Functions, Roy Bower

Theses and Dissertations

This dissertation is comprised and grounded in statistical theory with an application to solving real world problems. In particular, the development and implementation of multiple score tests under a variety of scenarios are derived, applied, and interpreted. In chapter 2, I propose a score test for independence of the marginals based on Lakshminarayana’s bivariate Poisson distribution. Each marginal distribution of the bivariate model is a univariate Poisson distribution, and the parameters of the bivariate distribution can be estimated using maximum likelihood methods. The simulation study shows that the score test maintains size close to the nominal level. To assess the …

Positioning Commuters And Shoppers Through Sensing And Correlation, Rufeng Meng

Theses and Dissertations

Positioning is a basic and important need in many scenarios of human daily activities. With position information, multifarious services could be vitalized to benefit all kinds of users, from individuals to organizations. Through positioning, people are able to obtain not only geo-location but also time related information. By aggregating position information from individuals, organizations could derive statistical knowledge about group behaviors, such as traffic, business, event, etc.

Although enormous effort has been invested in positioning related academic and industrial work, there are still many holes to be filled. This dissertation proposes solutions to address the need of positioning in people’s …

The Development Of A Miniature Spatial Heterodyne Raman Spectrometer For Applications In Planetary Exploration And Other Extreme Environments, Patrick Doyle Barnett

Theses and Dissertations

Space exploration is arguably one of the most important endeavors our species has ever undertaken. Rapid advances in rocketry and robotics in recent years has allowed for positioning of complex scientific instruments on other planets with a precision that was previously thought impossible. This, along with the need for more sophisticated chemical measurements to achieve the goals of new, more ambitious missions and recent advances in in-situ and remote spectroscopic techniques, has led to a boom in the use of spectroscopic instruments for space exploration. However, future missions to the moons of Jupiter and Saturn, along with other planetary bodies …

Delineation Of The Lower Permian Gas Sand Via Calibrated Avo And Pre-Stack Seismic Inversions In Majhol Field, Saudi Arabia, Abdullah Alhashel

Theses and Dissertations

The lower Permian formation in the central region of Saudi Arabia is a key hydrocarbon siliciclastic reservoir. However, in Majhol field, the reservoir properties vary laterally due to diagenesis and facies changes. Conventional seismic interpretation has failed to map the heterogeneities of the reservoir properties that control the gas production of this field. Therefore, there was an opportunity to employ more advanced quantitative seismic techniques to delineate the productive gas sand facies in the field.

The Majhol field was initially planned to be developed as an unconventional tight reservoir. Well-1 was drilled based on conventional seismic interpretation on the crest …

Utilization Of Satellite-Derived Salinity For Enso Studies And Climate Indices, Caroline Mary Corbett

Theses and Dissertations

Conventionally, El Niño-Southern Oscillation (ENSO) is studied using sea surface temperature (SST) observations in the central and eastern equatorial Pacific Ocean. Recently, sea surface salinity (SSS) in the equatorial Pacific has been studied in relation to the phases of ENSO. Previously, SSS was observed in the equatorial Pacific using the Tropical Ocean Global Atmosphere (TOGA) / Tropical Atmosphere Ocean (TOA), the Argo float network, and Oceanic General Circulation Models (OGCM). The launch of NASA’s Aquarius Salinity Mission and ESA’s Soil Moisture Ocean Salinity (SMOS) opened a new era in which high resolution global near real-time SSS observations are readily available. …

Physical Property Control In Core/Shell Inorganic Nanostructures For Fluorescence And Magnetic Targeting Applications, Stephen K. Roberts

Theses and Dissertations

Nanomaterials show immense promise for the future in numerous areas of application. Properties that are unique from the bulk material and are tunable allow for innovation in material design. This thesis will focus on controlling the physical properties of core/shell nanostructures to enhance the utility of the materials.

The first focus is on the impact of different solvent mixtures during the shell growth phase of SILAR based core/shell quantum dot synthesis is studied. Gaining insight into the mechanism for SILAR growth of core/shell nanoparticles allows improved synthetic yields and precursor binding, providing enhanced control to synthesis of core/shell nanoparticles. The …

3d Seismic Depth Imaging And Velocity Model Building In Anisotropic Media: Serri Oil And Gas Field, Saudi Arabia, Ali Jomaah Alsalem

Theses and Dissertations

Seismic imaging is a significant element in hydrocarbon exploration to locate drilling prospects and it relies mainly on an accurate velocity model. Prestack depth migration (PreSDM) versus traditional post-stack time migration has become a common method for seismic velocity model building and imaging. This methodology accounts for seismic velocity anisotropy of the propagating waves in the subsurface with a higher level of accuracy in positioning the seismic events in their true positions in the subsurface.

In this thesis, we examine a 303 km2 of 3D seismic data acquired by Saudi Aramco in the Serri field of North-West Saudi Arabia. The …

Hadronic Lorentz Violation In Chiral Perturbation Theory, Rasha Kamand

Theses and Dissertations

The leading-order Lorentz-violating hadronic Lagrange densities are constructed using chiral perturbation theory. This is done for both pions and nucleons starting from a two-flavor quark-level Lagrangian that consists of dimension-four Lorentzviolation operators. The effective Lagrangians are first constructed in the absence of external fields. The formalism is then extended to include interactions with external fields. The presence of Lorentz violation modifies the transformation behavior of external fields under the chiral group SU(2)L × SU(2)R. This in turn leads to modified pion and nucleon covariant derivatives. By expanding parts of both mesonic and baryonic Lagragians in terms of physical pion and …

Using Synthetic Lectins To Investigate Metastatic Potential In Colon Cancer, Erin E. Gatrone

Theses and Dissertations

Cancer is a disease that affects millions of people each year and it is well established that early diagnosis is a key factor towards improving survival rate, with that in mind there is a great need for better diagnostics. From the earliest onset of cancer, changes can be detected in the type and amount of carbohydrates expressed by the cancer cells, i.e., aberrant glycosylation. This process results in differing glycosylation patterns that can be used to detect cancer. Aberrant glycosylation can also greatly affect the potential of cancer cells to metastasize and can be used to stage the disease as …

Exclusive Π− Electroproduction Off The Neutron In Deuterium In The Resonance Region, Ye Tian

Theses and Dissertations

This dissertation focuses on extracting the exclusive γ∗n(p) → pπ-(p) reaction cross section from deuterium data. The existing γ∗n → pπ- event generator is modified to include the spectator (proton) information based on the CD-Bonn potential [28] to simulate the real data process. With this method, the exclusive quasi-free process is isolated successfully as demonstrated by the comparison of the spectator momentum distribution of the simulation with the missing momentum distribution of the data, and the kinematical final-state-interaction contribution factor RFSI is extracted directly from the data according to the ratio between the exclusive quasi-free and full cross sections. The …

Surface Chemistry And Transport Properties Of Ii-Vi Semiconductor Nanowires, Pravin Paudel

Theses and Dissertations

Semiconductor nanowires have been widely studied due to their unique properties such as width comparable to critical length-scales, high aspect ratio, and high carrier mobility. These unique properties make them a suitable candidate for various optical and electronic devices like photovoltaics, photodetectors, and field effect transistors. The nanowire surface plays an important role in the performance of these devices because of their high surface to volume ratio. The larger surface area of nanowires may provide better charge separation than planar heterostructures in photovoltaics by providing shorter distance to move for carrier before separation, however, presence of surface states may lead …

Some Issues In Markov Chain Monte Carlo Estimation For Item Response Theory, Han Kil Lee

Theses and Dissertations

Both the marginalized Bayesian modal estimation (MBME) and Metropolis-Hasting within Gibbs (MH/Gibbs) are the popular estimation methods for Item Response Theory (IRT). However, predictions from MBME and MH/Gibbs are not directly comparable because of two problems. First, the examinees with the same response pattern do not produce the same ability estimates from MH/Gibbs while MBME provides identical estimates. This problem can be handled by updating each response pattern instead of updating each examinee. Second, standard errors from MBME are smaller than standard error estimates from MH/Gibbs. This pattern occurs because of two speculated reasons; correlation between item parameter estimations and …

Rare Event Searches With Cuore Style Teo2 Bolometers, Nicholas Ivan Chott

Theses and Dissertations

In this dissertation we report on the first search for solar axions from atomic transitions in the solar core. A search for the 14.4 keV axion from the ground state transition in 57Fe in the sun was also performed, via the axioelectric effect in TeO2 bolometers, in the CUORE-0 experiment. Both axion searches are performed in the scope of the DSFZ invisible axion model. An upper bound on the axion-electron coupling constant of gae ≤ 3.1 x 10^-11 (95% CL) is obtained with 62.7 kg days of TeO2 exposure from the CUORICINO experiment. The CUORE-0 data results in a …

Hydro-Geological Flow Analysis Using Hidden Markov Models, Chandrahas Raj Venkat Gurram

Theses and Dissertations

Hidden Markov Models a class of statistical models used in various disciplines for understanding speech, finding different types of genes responsible for cancer and much more. In this thesis, Hidden Markov Models are used to obtain hidden states that can correlate the flow changes in the Wakulla Spring Cave. Sensors installed in the tunnels of Wakulla Spring Cave have recorded huge correlated changes in the water flows at numerous tunnels. Assuming the correlated flow changes are a consequence of system being in a set of discrete states, a Hidden Markov Model is calculated. This model comprising all the sensors installed …

Semiparametric Estimation Methods For Complex Accelerated Failure Time Model, Yinding Wang

Theses and Dissertations

The proportional hazards (PH) model and the accelerated failure time (AFT) model are the two most popular survival models in fitting the right-censored data. The AFT model is a useful alternative to the PH model, particularly when the PH assumption is not satisfied. Usually, the linear association is assumed with logarithm of survival time in the AFT model. However, the nonlinear association may exist in practice. The first project aims to handle the nonlinear component in the AFT model, which is called the semiparametric additive partial accelerated failure time (AP-AFT) model. Two estimation methods based on the rank-smooth method and …

Estimated Grass Grazing Removal Rate In A Semiarid Eurasian Steppe Watershed As Influenced By Climate, Xixi Wang, Shohreh Pedram, Tingxi Liu, Ruizhong Gao, Fengling Li, Yanyun Luo

Civil & Environmental Engineering Faculty Publications

Grazing removal rate of grasses needs to be determined for various climate conditions to address eco-environmental concerns (e.g., desertification) related to steppe grassland degradation. The conventional approach, which requires survey data on animal species and heads as well as grass consumption per individual animal, is too costly and time-consuming to be applied at a watershed scale. The objective of this study was to present a new approach that can be used to estimate grazing removal rate with no requirement of animal-related data. The application of this new approach was demonstrated in a Eurasian semiarid typical-steppe watershed for an analysis period …