Physical Sciences and Mathematics Commons^™

Probabilistic Methods, Joseph Kwaku Asafu-Adjei

Theses and Dissertations

The Probabilistic Method was primarily used in Combinatorics and pioneered by Erdös Pai, better known to Westerners as Paul Erdos in the 1950s. The probabilistic method is a powerful tool for solving many problems in discrete mathematics, combinatorics and also in graph .theory. It is also very useful to solve problems in number theory, combinatorial geometry, linear algebra and real analysis. More recently, it has been applied in the development of efficient algorithms and in the study of various computational problems.Broadly, the probabilistic method is somewhat opposite of the extremal graph theory. Instead of considering how a graph can behave …

Determination Of Size Fractions And Concentrations Of Airborne Particulate Matter Generated From Construction And Demolition Waste Processing Facilities, Jason M. Young

Theses and Dissertations

Construction and Demolition (C&D) processing and recycling facilities accept waste materials that are generated during construction and demolition activities. The processing facility sorts, processes, and transfers the material to another operation. A consequence of these processes is the generation of particulate matter.This study involved quantifying and qualifying airborne particulates at three C&D processing facilities. Active stationary particulate sampling devices were employed to quantify the particle sizes of interest. Results were compared to United States Environmental Protection Agency (EPA) National Ambient Air Quality Standards(NAAQS) and United States Occupational Safety and Health Administration (OSHA)standards.The results from this study are not valid for …

Study Of Covalent And Non-Covalent Interactions In Ternary Systems Involving: Metal/Dna-Rna/Protein, Where Metal = Platinum(Ii), Palladium(Ii), Anzellotti I. Atilio

Theses and Dissertations

Ternary systems comprising DNA/RNA, proteins and one (or more) metal ion are generating increased interest due to its biological relevance. The knowledge gained from the study of these systems could provide important clues regarding the precise mechanism for transcription factors, repair proteins and metal complexes with anti-tumoral/anti-viral activities.The interactions occurring among the components of these ternary systems can be broadly grouped into covalent and non-covalent. The first kind of interactions can lead to the irreversible transformation of the components in the system, while the second is thought to be reversible leading to transient states and fluxionality. Both kinds of interaction …

Phase Ii Trials Powered To Detect Activity In Tumor Subsets With Retrospective (Or Prospective) Use Of Predictive Markers, Grishma S. Sheth

Theses and Dissertations

Classical phase II trial designs assume a patient population with a homogeneous tumor type and yield an estimate of a stochastic probability of tumor response. Clinically, however, oncology is moving towards identifying patients who are likely to respond to therapy using tumor subtyping based upon predictive markers. Such designs are called targeted designs (Simon, 2004). For a given phase I1 trial predictive markers may be defined prospectively (on the basis of previous results) or identified retrospectively on the basis of analysis of responding and non-responding tumors. For the prospective case we propose two Phase I1 targeted designs in which a) …

Mechanisms Of Accumulation And Biological Consequences Of Polynuclear Platinum Compounds, Peyman Kabolizadeh

Theses and Dissertations

The novel trinuclear complex, BBR3464 has undergone Phase II clinical trials and been shown to have greater cytotoxicity and cellular uptake than clinical anticancer platinum drugs such as cisplatin, oxaliplatin and carboplatin. The clinical efficacy of cisplatin, oxaliplatin and carboplatin is limited due to acquired resistance and dose limiting side effects. The three major pharmacological factors contributing to the intrinsic cytotoxicity of, and cellular resistance to, platinum drugs are (i) cellular uptake and efflux of platinum; (ii) the frequency and nature of Pt-DNA adducts; and (iii) deactivating metabolic reactions with sulfur-containing nucleophiles. Since decreased cellular uptake of platinum drugs is …

Raman Scattering In Gan And Zno, Shinobu Nagata

Theses and Dissertations

The Micro-Raman scattering technique has been used for the study of GaN and ZnO. Capabilities of the Raman technique and existing literature on Raman spectroscopy in GaN and ZnO are reviewed. About 50 GaN and ZnO samples with a wide range of properties are studied. From the analysis of positions of the E2H and A1(LO) phonon modes, biaxial stress and plasmon coupling of the Al(LO) mode are observed and compared to a bulk GaN sample. The stress-related shift rate for the AI(LO) mode in hexagonal GaN is established to be 2.7 ± 0.4 cm-1/GPa through series of GaN with low …

Impacts Of Acid Mine Drainage On Carbon Cycling In Receiving Streams, Ernest W. Fonyuy

Doctoral Dissertations

"Field and laboratory investigations of acid mine drainage (AMD) contaminated and uncontaminated waters were conducted in order to determine and model processes and reaction mechanisms that control dissolved inorganic carbon (DIC) transformation and shifts in isotope ratio of DIC (Δ¹³C_DIC). The results show that AMD caused variable pH changes, overall decreases in Fe²⁺, alkalinity, and DIC, and increases in (Δ¹³C_DIC) in receiving streams. AMD caused more than 50 to > 98% seasonal DIC loss in stream water through CO₂ degassing. High DIC losses corresponded to high Fe²⁺ and lower or no HCO₃⁻ in the water samples, because …

Proximity Navigation For Map-Based Interfaces: Generalizing Menu Design For Multiple Dimensions, Brian Scott Malek

UNF Graduate Theses and Dissertations

The development of effective multidimensional map-based interfaces is an important area of research in need of design techniques and guidelines. To date, guidelines for multidimensional interfaces have been generalized from text-based interfaces and few experimental studies have been conducted to asses their effectiveness.

Guidelines for design were studied with the goal of extending the current body of knowledge about the usability of these interfaces. Based on design guidelines, multidimensional map-based interfaces with various levels of depth and breath, with and without scent-based components were used to perform simple and compound tasks. The goal of this study was to investigate the …

Dual Constraint Problem Optimization Using A Natural Approach: Genetic Algorithm And Simulated Annealing, James P. Sweeney

UNF Graduate Theses and Dissertations

Constraint optimization problems with multiple constraints and a large solution domain are NP hard and span almost all industries in a variety of applications. One such application is the optimization of resource scheduling in a "pay per use" grid environment. Charging for these resources based on demand is often referred to as Utility Computing, where resource providers lease computing power with varying costs based on processing speed. Consumers using this resource have time and cost constraints associated with each job they submit. Determining the optimal way to divide the job among the available resources with regard to the time and …

The Environmental Implications Of Aggradation In Major Braided Rivers At Mount Rainier National Park, Washington, Scott Robert Beason

Dissertations and Theses @ UNI

The purpose of this study is to quantify the historic rate of river bed filling, and to the extent possible, evaluate the factors that control sedimentation in river channels at Mount Rainier National Park. Mount Rainier is the tallest and the most glaciated of the Cascade volcanoes, located in southwestern Washington State. Steep, glacially-fed braided rivers radiate outward from the volcano in all directions and transport materials varying from fine sediment to cobbles and large boulders. As the gradient in the channels decreases downstream, sediment is no longer entrained and accumulates in the river bed. Over time, the river bed …

An Investigation Of Lead And Other Metal Contaminants In The Sediments Of Clearwater Lake, Missouri, Gary W. Krizanich

Doctoral Dissertations

"The purpose of this investigation is to characterize the spatial and temporal distribution and concentration of trace metals in sediments of Clearwater Lake. Understanding how trace metals are released to and transported in aquatic environments is important to the overall understanding of the impacts of mining on the natural environment. The main focus of this research will be on historic sedimentation within Clearwater Lake, which may act as a sink where mining related trace metals are stored. Because of their high preservation rates in basins, sediments can provide detailed chronostratigraphic histories of trace metal inputs in lakes. Sediment records can …

Electron Beam Characterization Of Carbon Nanostructures, Eric Samuel Mandell

Doctoral Dissertations

"Atom-thick carbon nanostructures represent a class of novel materials that are of interest to those studying carbon's role in fossil fuel, hydrogen storage, scaled-down electronics, and other nanotechnology. Electron microscope images of "edge-on" graphene sheets show linear image features due to the projected potential of the sheets. Here, intensity profiles along these linear features can measure the curvature of the sheet, as well as the shape of the sheet (i.e. hexagonal, triangular). Also, electron diffraction powder profiles calculated for triangular graphene sheet shapes show a broadening of the low frequency edge of diffraction rings, in comparison to those calculated for …

Incipient Continental Rifting: Insights From The Okavango Rift Zone, Northwestern Botswana, Baraka D. Kinabo

Doctoral Dissertations

"In this dissertation aeromagnetic, gravity, and Shuttle Radar Topography Mission Digital Elevation Model (SRTM DEM) data from the Okavango Rift Zone in northwest Botswana are used to map the distribution of rift and basement structures. The distribution of these structures provide useful insights into the early stages of continental rifting. The objectives of this study are (1) assessing the role of pre-existing structures on rift basin development, (2) characterizing the geometry of the nascent rift basins, (3) documenting fault growth and propagation patterns, and (4) investigating the border fault development"--Abstract, page iv.

Assessment Of The Source And Transformation Of Nitrate In The Cedar River Watershed By Using Stable Isotopes Of Nitrogen, Sushil Gautam

Dissertations and Theses @ UNI

Stable isotopes of nitrogen were used to assess the source and fate of nitrate in the Cedar River Watershed, Iowa. Ground water samples from 20 private wells and surface water samples from 10 sites in the Cedar River and its tributaries were collected. A total of 90 samples were collected during the growing season from May through September 2006. In 35% of the wells, nitrate concentration exceeded the U.S. Environmental Protection Agency's recommended maximum contaminant level (MCL) of 45 mg/1 (as NO3-) for drinking purposes. Eight (8) out of 10 samples exceeded MCL for nitrate in the first set of …

Synthetic Methods For Biologically Relevant Organofluorine Compounds, Meher Perambuduru

Doctoral Dissertations

"This thesis describes novel synthetic methodologies for the synthesis of biologically relevant organofluorine compounds"--Abstract, page iii.

Effects Of Combined Exposure To Ethanol And Ionizing Radiation On The Antioxidant Status Of In Vitro And In Vivo Models, Joshua Ogony

Doctoral Dissertations

"Ethanol and ionizing radiation exposure are independently known to cause tissue damage through various mechanisms. Non-enzymatic and enzymatic metabolism of ethanol, the latter via the cytochrome P₄₅₀2E1-dependent pathway, produces free radicals which deplete cellular glutathione (GSH). Ionizing radiation exposure has been shown to induce lipid peroxidation, DNA damage, protein oxidation, and GSH depletion, as well. It was postulated that initial exposure to ethanol, followed by ionizing radiation, would result in heightened oxidative stress. The in vitro model used in this investigation was HepG2 cells (human hepatocellular liver carcinoma cell line), while the in vivo model was Cd-1 mice"--Abstract, page iii.

Towards The Computation Of The Convex Hull Of A Configuration From Its Corresponding Separating Matrix, Elie Feder, David Garber

Publications and Research

In this paper we cope with the following problem compute the size of the convex hull of a configuration C where the given data is the number of separating lines between any two points of the configuration (where the lines are generated by pairs of other points of the configuration)

We give an algorithm for the case that the convex hull is of size 3 and a partial algorithm and some directions for the case that the convex hull is of size bigger than 3.

Decrypting The Code Of Ethics: The Relationship Between An Attorney's Ethical Duties And Network Security, Ash Mayfield

Oklahoma Law Review

No abstract provided.

Generalized No-Broadcasting Theorem, Howard Barnum, Jonathan Barrett, Matthew S. Leifer, Alex Wilce

Mathematics, Physics, and Computer Science Faculty Articles and Research

We prove a generalized version of the no-broadcasting theorem, applicable to essentially any nonclassical finite-dimensional probabilistic model satisfying a no-signaling criterion, including ones with ‘‘superquantum’’ correlations. A strengthened version of the quantum no-broadcasting theorem follows, and its proof is significantly simpler than existing proofs of the no-broadcasting theorem.

Generating Ontologies Via Language Components And Ontology Reuse, Deryle W. Lonsdale, Yihong Ding, David W. Embley, Martin Hepp, Li Xu

Faculty Publications

Realizing the Semantic Web involves creating ontologies, a tedious and costly challenge. Reuse can reduce the cost of ontology engineering. Semantic Web ontologies can provide useful input for ontology reuse. However, the automated reuse of such ontologies remains underexplored. This paper presents a generic architecture for automated ontology reuse. With our implementation of this architecture, we show the practicality of automating ontology generation through ontology reuse. We experimented with a large generic ontology as a basis for automatically generating domain ontologies that fit the scope of sample natural-language web pages. The results were encouraging, resulting in five lessons pertinent to …

Coupling Coherence Distinguishes Structure Sensitivity In Protein Electron Transfer, Tatiana Prytkova, Igor V. Kurnikov, David Beratan

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Quantum mechanical analysis of electron tunneling in nine thermally fluctuating cytochrome b562 derivatives reveals two distinct protein-mediated coupling limits. A structure-insensitive regime arises for redox partners coupled through dynamically averaged multiple-coupling pathways (in seven of the nine derivatives) where heme-edge coupling leads to the multiple-pathway regime. A structure-dependent limit governs redox partners coupled through a dominant pathway (in two of the nine derivatives) where axial-ligand coupling generates the single-pathway limit and slower rates. This two-regime paradigm provides a unified description of electron transfer rates in 26 ruthenium-modified heme and blue-copper proteins, as well as in numerous photosynthetic proteins.

A Functional Calculus In A Non Commutative Setting, Fabrizio Colombo, Graziano Gentili, Irene Sabadini, Daniele C. Struppa

Mathematics, Physics, and Computer Science Faculty Articles and Research

In this paper we announce the development of a functional calculus for operators defined on quaternionic Banach spaces. The definition is based on a new notion of slice regularity, see [6], and the key tools are a new resolvent operator and a new eigenvalue problem. This approach allows us to deal both with bounded and unbounded operators.

Improved Associated Conditions In Rapid Intensifications Of Tropical Cyclones, Ruixin Yang, J. Tang, Menas Kafatos

Mathematics, Physics, and Computer Science Faculty Articles and Research

Rapid intensification (RI) of tropical cyclones (TC) is a major error source in TC intensity forecasting. In order to improve the estimates of RI probability, association rules are used to facilitate the process of mining for candidate sets of conditions. Compared to the relation analysis method, the technique of association rules can simply explore associations among multiple conditions. Our mining results identified a reduced predictor set with fewer factors identified in previous studies but improved RI probabilities. That is, the RI probability with three conditions satisfied: low vertical shear, high humidity, and the TC being in an intensification phase is …

Influences Of Winter Haze On Fog/Low Cloud Over The Indo-Gangetic Plains, Ritesh Gautam, N. C. Hsu, Menas Kafatos

Mathematics, Physics, and Computer Science Faculty Articles and Research

The aerosol loading in south Asia has increased considerably because of the growing population, urbanization, and industrialization in recent years. To understand the effects of aerosols on cloud properties in this region, we have analyzed an extensive collection of aerosol and cloud properties, obtained from the Moderate resolution Imaging Spectroradiometer (MODIS) data, over the Indian subcontinent during winter 2000–2006. During these winter months, the Indo-Gangetic (IG) plains, in the northern part of India, are subjected to dense haze and fog on the basis of MODIS climatology of aerosol optical depth and cloud properties (cloud effective radius, cloud top pressure, and …

Carathéodory Functions In The Banach Space Setting, Daniel Alpay, Olga Timoshenko, Dan Volok

Mathematics, Physics, and Computer Science Faculty Articles and Research

We prove representation theorems for Carathéodory functions in the setting of Banach spaces.

Quantum Dot Photolithography, Raghuveer Reddy Gadipalli

Doctoral Dissertations

"This dissertation presents a simple method for the photolithographic patterning of silica hydrogel monoliths and planar substrates with quantum dots and inorganic semiconductor nanoparticles. We developed a method for surface patterning and bulk (3D) patterning of silica hydrogel monoliths and surface patterning of planar substrates with CdS, CdSe, PbS and PbSe quantum dots using infrared light, ultraviolet light, X-rays, and multi-photon ionization radiation. Precursor combinations were prepared which can readily dissociate with IR, UV, X-rays, and multi-photon ionization radiation. Different capping agents were used for improving quantum dot size distribution. The luminescence quantum yield of the composites can be increased …

Performance Analysis Of Security Protocols, Praveen Kumar Donta

UNF Graduate Theses and Dissertations

Security is critical to a wide range of applications and services. Numerous security mechanisms and protocols have been developed and are widely used with today’s Internet. These protocols, which provide secrecy, authentication, and integrity control, are essential to protecting electronic information.

There are many types of security protocols and mechanisms, such as symmetric key algorithms, asymmetric key algorithms, message digests, digital certificates, and secure socket layer (SSL) communication. Symmetric and asymmetric key algorithms provide secrecy. Message digests are used for authentication. SSL communication provides a secure connection between two sockets.

The purpose of this graduate project was to do performance …

The Effects Of Histone H1 And Benzo[A] Pyrene On Chromatin Modifying Complexes., Zeina Salim Al Natour

Theses

Packaging of DNA into the condensed structure of chromatin presents a barrier to many cellular processes that require DNA access such as transcription and replication. This problem is solved, in part, by the action of various complexes that modify the chromatin structure so that it becomes more accessible and, therefore, a more suitable platform for these processes. ATP-dependent chromatin remodeling complexes and histone acetyltransferases are examples of many chromatin modifying complexes that work to alleviate chromatin-mediated repression. Histone H1 is an important component of chromatin which serves in both stabilizing and folding of chromatin into a higher order structure. Many …

Predictive Oncology: A Review Of Multidisciplinary, Multiscale In Silico Modeling Linking Phenotype, Morphology And Growth, Sandeep Sanga, Hermann B. Frieboes, Xiaoming Zheng, Robert Gatenby, Elaine L. Bearer, Vittorio Cristini

Faculty, Staff and Student Publications

Empirical evidence and theoretical studies suggest that the phenotype, i.e., cellular- and molecular-scale dynamics, including proliferation rate and adhesiveness due to microenvironmental factors and gene expression that govern tumor growth and invasiveness, also determine gross tumor-scale morphology. It has been difficult to quantify the relative effect of these links on disease progression and prognosis using conventional clinical and experimental methods and observables. As a result, successful individualized treatment of highly malignant and invasive cancers, such as glioblastoma, via surgical resection and chemotherapy cannot be offered and outcomes are generally poor. What is needed is a deterministic, quantifiable method to enable …

High-Resolution Vascular Imaging Of The Rat Spine Using Liposomal Blood Pool Mr Agent, K B Ghaghada, K H J Bockhorst, S Mukundan, A V Annapragada, P A Narayana

Faculty, Staff and Student Publications

BACKGROUND AND PURPOSE: High-resolution, vascular MR imaging of the spine region in small animals poses several challenges. The small anatomic features, extravascular diffusion, and low signal-to-noise ratio limit the use of conventional contrast agents. We hypothesize that a long-circulating, intravascular liposomal-encapsulated MR contrast agent (liposomal-Gd) would facilitate visualization of small anatomic features of the perispinal vasculature not visible with conventional contrast agent (gadolinium-diethylene-triaminepentaacetic acid [Gd-DTPA]). METHODS: In this study, high-resolution MR angiography of the spine region was performed in a rat model using a liposomal-Gd, which is known to remain within the blood pool for an extended period. The imaging …