Physical Sciences and Mathematics Commons^™

Adverse Childhood Experiences, Resilience, And Syringe Services Program Attendance Among Persons Who Inject Drugs In Northeast Georgia, Usa: A Mediation Analysis, Mohammad Rifat Haider, Samantha Clinton, Monique J. Brown, Nathan B. Hansen

Faculty Publications

Background: Syringe services programs (SSP) are evidence-based venues offering harm reduction services to persons who inject drugs (PWID), such as sterile syringes, STI/HIV testing, and linkage to care to decrease drug use-related morbidities and mortalities. Adverse childhood experiences (ACEs) have been linked with reduced resilience, while increased resilience can help PWID attend SSPs. This study examined the potential mediating role of resilience between ACEs and SSP attendance among PWID.

Methods: Data were collected from adult HIV-negative PWID in northeast Georgia, between February-December 2023 (N = 173). Data were collected on SSP attendance (Yes vs. No), resilience, and ACEs. Covariates included …

Geographic Disparities In Unpaid Caregiving, Emma Kathryn Boswell, Monique J. Brown Ph.D., Mph, Lorie Donelle Phd, Rn, Fcan, Nicholas Yell, Taryn Farrell, Peiyin Hung Ph.D., Elizabeth Crouch Ph.D.

Faculty Publications

Purpose: An updated, nationally representative examination of rural–urban differences in the experiences, health, and well-being of caregivers is needed; previous research on this topic uses older data or has limited generalizability. This study examines rural–urban differences in the characteristics, experiences, and health of caregivers. Methods: The 2021–2022 Behavioral Risk Factor Surveillance System (n = 44,274 unpaid caregivers) was used, with rurality defined according to the 2013 National Center for Health Statistics (NCHS) Urban-Rural Classification Scheme. Chi-square tests compared rural–urban differences in these caregivers’ characteristics, including demographic factors, caregiving intensity (e.g., weekly hours spent caregiving, reason for caregiving, past-month ADL/IADL assistance), …

A Standardized Methodology For Evaluating A Digital Badging System [ Data Package ], Benjamin T. Pederson, Mark G. Reith, Ralucca Gera, David S. Long, Edward D. White, Jonathan Zemmer

Faculty Publications

Digital badges, a form of micro-credentials, have grown in popularity over the past decade. However, few standard processes exist to assess the potential of digital badging systems within an organization. This study proposes a generalizable methodology for comparing a badging system with other methods of recording skills and competencies. The experimental design is tested using the military's cyber operations community as the target organization. Finally, mixed-method data from thirty-six participants is analyzed in accordance with the methodology. Based on the results, digital badging systems are perceived to be more valuable and usable than a current method of military talent management. …

Urbanization Impacts Dissolved Organic Matter Concentration And Quality In A Southeastern United States Watershed, Gwendolyn M. Hopper, Erik M. Smith, Jade Dormoy-Boulanger, Claudia R. Benitez-Nelson

Faculty Publications

Blackwater rivers are named due to their exceptionally high concentrations of chromophoric dissolved organic matter (CDOM). They are the predominant lotic ecosystem in the United States Southeastern Coastal Plain, a region experiencing some of the nation’s highest rates of development. This study assessed variability in DOM concentration and composition across forested to urbanized blackwater systems in coastal South Carolina, U.S. Dissolved organic carbon and nutrient concentrations as well as absorbance and fluorescence optical properties reveal that urban sites have lower concentrations, elemental ratios, and less complex DOM. In contrast, forested blackwater sites have concentrations an order of magnitude higher, elevated …

Toward Quantifying Interpolation Uncertainty In Set-Line Spacing Hydrographic Surveys, Elias Adediran, Christos Kastrisios, Kim Lowell, Glen Rice, Qi Zhang

Faculty Publications

The oceans remain one of Earth’s last great unknowns, with about 74% still unmapped to modern standards. Consequently, interpolation is employed to create seamless digital bathymetric models (DBMs) from incomplete hydrographic datasets, but this introduces unquantified depth uncertainties. This study aims to estimate and characterize uncertainties arising from set-line spacing hydrographic surveys, which are important for nautical charting, navigational safety, and many other applications. By sampling at different line spacings four complete coverage testbeds that vary in slope and roughness, the study interpolates across entire testbed areas using Spline, Inverse Distance Weighting, and Linear interpolation. The resulting interpolation uncertainties are …

Convergent Close-Coupling Approach To Electron Impact Dissociation Of The Polyatomic Molecule H 3 + And Its Isotopologues, Reese K. Horton, Michael V. Pak, Igor Bray, Dmitry V. Fursa

Faculty Publications

Cross sections for electron impact dissociative excitation and ionization in scattering on vibrationally excited levels of the ground electronic state of H₃⁺ and its isotopologues are reported in the energy range of 8 to 1000 eV. Calculations have been performed using a newly developed version of the molecular convergent close-coupling code. Cross sections for total dissociative excitation, ionization yielding atomic fragments such as D⁺, and the total inelastic cross section are presented. Good agreement with available experiments has been demonstrated.

Convergent Close-Coupling Approach To Electron Scattering On H3+ : Scattering Dynamics And Dissociative Processes, Reese K. Horton, Michael V. Pak, Igor Bray, Dmitry V. Fursa

Faculty Publications

Cross sections for electron impact dissociative excitation and ionization in scattering on vibrationally excited levels of the ground electronic state of H₃⁺, D₃⁺, and T₃⁺ are reported in the energy range of 8–1000 eV. Calculations have been performed using a newly developed version of the molecular convergent close-coupling code. Convergence of the cross sections with the size of the projectile partial-wave and close-coupling expansions is examined. Branching ratios and cross sections for the yields of D₂⁺ and D⁺ from dissociative excitation of D₃⁺ are presented and isotope …

Accelerated Multiobjective Calibration Of Fused Deposition Modeling 3d Printers Using Multitask Bayesian Optimization And Computer Vision, Craig S. Ganitano, Benji Maruyama, Gilbert L. Peterson

Faculty Publications

Proper process parameter calibration is critical to the success of fused deposition modeling (FDM) three-dimensional (3D) printing, but is time-consuming and requires expertise. While existing systems for autonomous calibration have demonstrated success in calibrating for a single objective, users may need to balance multiple conflicting objectives. Herein, an easily deployable, camera-based system for autonomous calibration of FDM printers that optimizes for both part quality and completion time is presented. Autonomous calibration is achieved through a novel, multifaceted computer vision characterization and a multitask learning extension to Bayesian optimization. The system is demonstrated on four popular filament types using two distinct …

Variations In Hawaiian Plume Flux Controlled By Ancientmantle Depletion, Paul Béguelin, Andreas Stracke, Maxim D. Ballmer, Shichen Huang, Michael Wilig, Michael Bizimis

Faculty Publications

Mantle plumes—upwellings of buoyant rock in Earth's mantle—feed hotspot volcanoes such as Hawai‘i. The size of volcanoes along the Hawai‘i–Emperor chain, and thus the magma flux of the Hawaiian plume, has varied over the past 85 million years. Fifteen and two million years ago, rapid bursts in magmatic production led to the emergence of large islands such as Pūhāhonu, Maui Nui and Hawai‘i, but the underlying mechanisms remain enigmatic. Here, we use new radiogenic Ce–Sr–Nd–Hf isotope data of Hawaiian shield lavas to quantify the composition and proportion of the different constituents of the Hawaiian plume over time. We find that …

Childhood Sexual Trauma, Substance Use, And Antiretroviral Therapy Adherence Among Older Adults Living With Hiv: A Mediational Analysis, Monique J. Brown, Josie Zhang, Prince Nii Ossah Addo, Amandeep Kaur, Daniel Amoatika, Elizabeth L. Crouch Ph.D., Steven A. Cohen

Faculty Publications

Childhood sexual abuse (CSA) is linked to substance use and lower antiretroviral therapy (ART) adherence. However, studies examining the mediational role of substance use between CSA and ART adherence are lacking. Therefore, the aim of this study was to determine the potential mediational role of substance use between CSA and ART adherence among older adults living with HIV (OALH) (n = 91). Mediation analyses assessed the direct and indirect relationships between CSA, substance use, and ART adherence. Statistically significant differences existed in substance use by gender (male vs. female: 12.3 vs. 9.97) and ART adherence by race (Black vs. …

Pilot Study: Initial Investigation Suggests Differences In Emt-Associated Gene Expression In Breast Tumor Regions, Kylie L. King, Hamed Abdollahi, Zoe Dinkel, Alannah Akins, Homayoun Valafar, Heather Dunn

Faculty Publications

Triple negative breast cancer (TNBC) is the most aggressive subtype and disproportionately affects African American women. The development of breast cancer is highly associated with interactions between tumor cells and the extracellular matrix (ECM), and recent research suggests that cellular components of the ECM vary between racial groups. This pilot study aimed to evaluate gene expression in TNBC samples from patients who identified as African American and Caucasian using traditional statistical methods and emerging Machine Learning (ML) approaches. ML enables the analysis of complex datasets and the extraction of useful information from small datasets. We selected four regions of interest …

Deep Learning-Based Superconductivity Prediction And Experimental Tests, Daniel Kaplan, Adam Zheng, Joanna Blawat, Rongying Jin, Robert J. Cava, Viktor Oudovenko, Gabriel Kotliar, Anirvan M. Sengupta, Weiwei Xie

Faculty Publications

The discovery of novel superconducting materials is a long-standing challenge in materials science, with a wealth of potential for applications in energy, transportation and computing. Recent advances in artificial intelligence (AI) have enabled expediting the search for new materials by efficiently utilizing vast materials databases. In this study, we developed an approach based on deep learning (DL) to predict new superconducting materials. We have synthesized a compound derived from our DL network and confirmed its superconducting properties in agreement with our prediction. Our approach is also compared to previous work based on random forests (RFs). In particular, RFs require knowledge …

Associations Between Social Determinants Of Health And Mental Health Disorders Among U.S. Population: A Cross-Sectional Study, S. Tanarsuwongkul

Faculty Publications

Aims

The impact of social determinants of health (SDOH) on mental health is increasingly realized. A comprehensive study examining the associations of SDOH with mental health disorders has yet to be accomplished. This study evaluated the associations between five domains of SDOH and the SDOH summary score and mental health disorders in the United States.

Methods

We analyzed data from a diverse group of participants enrolled in the All of Us research programme, a research programme to gather data from one million people living in the United States, in a cross-sectional design. The primary exposure was SDOH based on Healthy …

Analysis Of Phytochemicals In Watercress Leaves Using Chromatographic, Spectroscopic And In-Vitro Approaches, Bidisha Roy Sengupta

Faculty Publications

No abstract provided.

Biofilm-Based Biomonitoring Of Treated Wastewater Using Bacillus Thuringiensis: Toward Sustainable Water Reuse, Bidisha Roy Sengupta, Kefa K. Onchoke, Olabisi O. Ogunlewe, Robert Friedfeld

Faculty Publications

No abstract provided.

Durable Oxyfluoride Waste Forms For Salt Wastes From Molten Salt Reactors, Alevtina A. Maksimova, Jake W. Amoroso, Matthew Page, Gregory Morrison, Hans Conrad Zur Loye

Faculty Publications

Molten salt reactors (MSRs) are promising technology to replace traditional light and heavy water reactors in the near future. Waste management for MSRs, however, remains a pressing concern that needs to be resolved prior to realizing deployment of MSRs. Specifically, the generated salt waste needs to be safely sequestered, a task made difficult by the high solubility of the salt waste that can cause the release of radionuclides into the environment. This work demonstrates a new approach to immobilize multiple fluoride salts into a single waste form by converting highly-soluble fluorides to durable and stable oxyfluorides. Notably, we report a …

Identifying All Matches Of A Rigid Object In An Input Image Using Visible Triangles, Abdullah N. Arslan

Faculty Publications

It has been suggested that for objects identifiable by their corners, every triangle formed by these corner points can serve as a reference for detecting other corner points. This approach enables effective rigid object detection, including partial matches. However, when there are many corner points, the implementation becomes impractical due to excessive memory requirements. To overcome this, we propose a new algorithm that leverages Delaunay triangulation, considering only the triangles generated by the Delaunay triangulation to reduce the complexity of the original approach. Our algorithm is significantly faster and requires significantly less memory, offering a viable solution for large problem …

Temporal Network Analysis Of Comorbidities Among People With Hiv In South Carolina, Yunqing Ma, Matthew Lohman Ph.D., Monique J. Brown Ph.D., Mph, Yichen Li, Xiaoming Li Ph.D., Bankole Olatosi Ph.D., Jiajia Zhang Ph.D.

Faculty Publications

Introduction: People with HIV experience a high rate of comorbidities that can complicate their health outcomes. Understanding the prevalence, interrelationships and temporal development of these comorbidities is crucial for improving health management and quality of life for people with HIV. Methods: We used a population-based cohort extracted from statewide electronic health record (EHR) data in South Carolina (SC), including 18 649 people with HIV who survived at least 1 year after HIV diagnosis between January 1, 2005, and December 31, 2020. Comorbidities and organ systems were classified using ICD-10 codes. Network analysis was performed to assess the closeness centrality among …

Permutations Minimizing The Number Of Collinear Triples, Joshua Cooper, Jack Hyatt

Faculty Publications

We characterize the permutations of Fq whose graph minimizes the number of collinear triples and describe the lexicographically-least one, confirming a conjecture of Cooper-Solymosi. This question is connected to Dudeney’s No-3-in-a-Line problem, the Heilbronn triangle problem, and the structure of finite plane Kakeya sets. We discuss a connection with complete sets of mutually orthogonal latin squares and state a few open problems primarily about general finite affine planes.

A Collaborative Assessment Of Coastal Ocean Acidification Monitoring In Maine & Standard Operating Procedures And Best Practices For The Collection Of Continuous Ph Data In Coastal Marine Environments, Christopher W. Hunt, Curtis Bohlen, Mike Doan, Jeremy Miller

Faculty Publications

The ‘Sensor Squad’ of the Maine Ocean Climate Collaborative is the product of a 2023 Maine Coastal and Marine Climate Action Fund grant to conduct “A two-year pilot project designed to address and overcome technological barriers to ocean acidification data collection, develop protocols to elevate quality assurance and ensure comparable data, and meet regularly to discuss project results and data compilation”. The Squad consists of representatives from Friends of Casco Bay (FOCB), Wells National Estuarine Research Reserve (WNERR), and the University of New Hampshire (UNH). This report is a summary of their efforts to assess affordable, repeatable means of continuously …

The Serendipity Of Discovery: Life Of A Geochemist, Willard S. Moore

Faculty Publications

My strategy for writing this autobiography is to use examples of how working on seemingly different projects can often lead to outcomes more important than originally envisioned. Serendipity is a "happy accident"; specifically, the accident of discovering something useful without directly looking for it. This often occurs when two research projects converge unexpectedly. The main text contains examples of how serendipity has led me to important discoveries including: (a) finding surprisingly high ²²⁸Ra activities in the ocean, (b) developing a means of rapidly and quantitatively extracting radium from seawater, (c) devising a rapid, sensitive method of measuring ²²⁴Ra …

Navigating Together: The Conav Testbed And Framework For Benchmarking Cooperative Localization, Rohith Boyinine, Jayanth Ammapalli, Anusna Chakraborty, Rajnikant Sharma, Kevin Brink, Clark N. Taylor

Faculty Publications

This paper presents CoNaV, a comprehensive framework for creating a multi-vehicle cooperative localization (CL) testbed designed to support the benchmarking, development, and deployment of cooperative navigation algorithms. Given the essential role of CL in improving localization accuracy for both defense and civilian applications, CoNaV provides a robust environment for rigorously validating algorithms under real-world conditions. By establishing a benchmark for CL algorithms, CoNaV lays a foundation for advancing research into more sophisticated and distributed CL solutions. This framework highlights the potential of cooperative navigation to enhance multi-vehicle operations and offers a scalable, practical approach for future developments in CL technology.

Maternal Vulnerability Index And Severe Maternal Morbidity, Nansi S. Boghossian, Joshua Radack, Molly Passarella, Ciaran S. Phibbs, Lucy T. Greenberg, Jeffrey S. Buzas, George R. Saade, Jeannette Rogowski, Scott A. Lorch

Faculty Publications

Importance: Few studies have investigated the association of composite measures of neighborhood social determinants of health with severe maternal morbidity (SMM), and no research has examined this association for indices tailored to maternal health. Objective: To examine the association of scores in the Maternal Vulnerability Index (MVI), a tool developed to measure maternal risk of adverse health outcomes, with SMM. Design, Setting, and Participants: This retrospective, population-based cohort study was conducted in 5 states (2008-2020 for Michigan, Oregon, and South Carolina; 2008-2018 for Pennsylvania; and 2008-2012 for California) among individuals delivering a fetal death or a live birth between 22 …

Caregiving Burdens Of Task Time And Task Difficulty Among Paid And Unpaid Caregivers Of Persons Living With Dementia, Matthew Lee Smith, Jodi L. Southerland, Malinee Neelamegam, Gang Han, Shinduk Lee, Chung Lin Kew, Juanita Dawne R. Bacsu, Elyse Couch, Steffi M. Kim, Monique J. Brown Ph.D., Mph, Ayse Malatyali, Lucas Wilson, Zahra Rahemi, Jeremy Holloway, Marcia G. Ory

Faculty Publications

Background: Demands of caregivers of persons living with dementia (PLWD) are often influenced by the context of their caregiving situation. This study examines common and unique factors associated with caregiving burden in terms of task time and task difficulty among paid and unpaid caregivers of PLWD. Methods: Cross-sectional baseline survey data were analyzed from 107 paid and unpaid caregivers of PLWD participating in a larger NIH-funded study assessing the feasibility of using a novel in-situ sensor system. Oberst Caregiving Burden Scale constructs of task time and task difficulty served as dependent variables. Two least squares regression models were fitted, controlling …

Investing In The Development Of The Next Generation Of Mch Leaders, Karen A. Mcdonnell, Jamal Percy, Lisa Anders, Monique J. Brown Ph.D., Mph, Alice R. Richman, Julianna Deardorff, Monica S. Ruiz, Jihong Liu Sc.D., Kelli Russell, Audrey Snyder, Cassondra Marshall

Faculty Publications

The public health landscape is constantly evolving to address the strengths and needs of the community. Training for the public health workforce is leading the way, establishing an ecosystem approach that integrates individuals within social, political, and environmental contexts to promote health equity within a framework of social justice. One area of public health that is innovatively preparing the next generation of leaders is maternal and child health (MCH). In the United States, key indicators of health disparities within MCH remain stagnant, highlighting the need for training programs that develop future MCH professionals from diverse backgrounds. These professionals will deliver …

Healthcare Providers’ Perspective On Hiv Testing And Hypothetical Mhealth-Connected Linkage To Care Among Men Who Have Sex With Men (Msm) In South Carolina, Tony Brown, Prince Nii Ossah Addo, Monique J. Brown Ph.D., Mph, Xiaoming Li, Oluwafemi Adeagbo

Faculty Publications

Background: HIV continues to be an important public health concern in South Carolina (SC). However, an examination of providers’ willingness to use mHealth technologies to address ongoing barriers to HIV care and prevention strategies, particularly among men who have sex with men (MSM) is currently lacking in SC. We therefore explored HIV care providers’ perceptions of HIV testing and treatment uptake among MSM, and providers’ willingness to use mHealth technology to address barriers to HIV testing and treatment in SC. Methods: Between August and December 2021, we conducted semistructured virtual interviews with 10 HIV care providers recruited purposively based on …

Sars-Cov-2 Detection And Persistence In A Remote Amazonian Settlement, Glauco M. Silva, Roberto C. Ilacqua, Franciely G. Gonçalves, Carla M. Santana, Felipe T. Jordão, Paula R. Prist, Melissa S. Nolan Ph.D., Mph, Andreia F. Brilhante, Marcia A. Sperança, Gabriel Z. Laporta

Faculty Publications

Background: COVID-19 continues to pose a major global health challenge. Despite its geographic distance from Brazil’s major urban centers, Acre state has experienced notable outbreaks. This study assessed the detection and persistence of SARS-CoV-2 in the rural settlement of Santa Luzia, located in the remote municipality of Cruzeiro do Sul, Acre state, Brazil. Methods: In July 2022, a cross-sectional survey was conducted at 40 sites from an ongoing environmental study, selected by deforestation patterns and proximity to health posts. Saliva samples were collected from residents aged 5–90 years, followed by nucleic acid extraction and multiplex RT-qPCR for SARS-CoV-2 detection. Results: …

Editorial: Artificial Intelligence For Smart Health: Learning, Simulation, And Optimization, Bing Yao, Nathan Gaw, Hyo Kyung Lee

Faculty Publications

With rapid developments in medical sensing and imaging, we now live in an era of data explosion in which large amounts of data are readily available in clinical environments. The fast-growing biomedical and healthcare data provide unprecedented opportunities for data-driven scientific knowledge discovery and clinical decision support. Our Research Topic aims to catalyze synergies among biomedical informatics, machine learning, computer simulation, operations research, systems engineering, and other related fields with three specific goals: (1) develop cutting-edge data-driven models to accelerate scientific knowledge discovery in biomedicine using healthcare data collected from laboratory systems, imaging systems, and medical and sensing devices; (2) …

Molten Flux Synthesis Of Plutonium (Iv) Silicates K2Pusi2O7 And Rb2Pusi6O15, Travis K. Deason, Gregory Morrison, Amir Mofrad, Jake Amoroso, David Diprete, Theodore M. Besmann, Shanna L. Estes, Hans Conrad Zur Loye

Faculty Publications

Few plutonium containing silicates have been reported in the literature and only one other tetravalent plutonium silicate structure has been reported using the flux growth method. With the goal of understanding actinide incorporation into silicates, we describe herein two new plutonium (IV) silicates, Rb2PuSi6O15 and K2PuSi2O7, synthesized using a mixed alkali chloride/alkali fluoride flux growth. Both structures crystallize in the C2/c space group with lattice parameters a=24.2980(10) Å, b=7.1466(3) Å, c=17.2025(8) Å and 96.6560(10)° for Rb2PuSi6O15, and a=9.9478(2) Å, b=5.59820 (10) Å, c=13.1848(2) Å, and 105.7400(10)° for K2PuSi2O7. Comparisons to the synthesis of other reported alkali actinide silicates (Ce, U, …

Racial And Ethnic Differences In Outcomes Of Neonates Born At Less Than 30 Weeks' Gestation, 2018-2022, Nansi S. Boghossian, Marco Geraci, Erika M. Edwards, Jeffrey D. Horbar

Faculty Publications

Importance: Previous research has examined outcomes among very preterm newborns by the birthing parent's race and ethnicity, but knowledge about these trends during the COVID-19 pandemic is limited. Objective: To examine trends in outcomes among Black, Hispanic, and Asian preterm newborns compared with White preterm newborns. Design, Setting, and Participants: This cohort study (2018-2022) took place at 774 neonatal intensive care units in the Vermont Oxford Network. Participants were newborns born at 22 to 29 weeks' gestation. Exposure: Race and ethnicity. Main Outcomes and Measures: The primary outcomes were mortality and complications, including respiratory distress syndrome, necrotizing enterocolitis (NEC), early-onset …