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Articles 181 - 210 of 7346

Full-Text Articles in Physical Sciences and Mathematics

Ai-Assisted Surface-Enhanced Raman Spectroscopy For Cardiovascular Diagnostics: From Plasmonic Materials To Clinical Translation, Anju Joshi, Gymama Slaughter Jan 2026

Ai-Assisted Surface-Enhanced Raman Spectroscopy For Cardiovascular Diagnostics: From Plasmonic Materials To Clinical Translation, Anju Joshi, Gymama Slaughter

Center for Bioelectronics Publications

Raman spectroscopy (SERS) has emerged as a powerful analytical technique, offering molecular fingerprint specificity and ultrasensitive detection of cardiac biomarkers. Recent advances in plasmonic nanostructures, surface functionalization strategies, and flexible sensing platforms have significantly improved the analytical performance of SERS-based biosensors. In parallel, the integration of artificial intelligence (AI) and machine learning has enabled robust interpretation of complex spectral datasets, facilitating automated biomarker classification and improved diagnostic accuracy in heterogeneous biological environments. Despite these advances, the field remains fragmented, with limited integration between nanomaterial design, biomarker selection, and data-driven analysis, and persistent challenges related to reproducibility, standardization, and clinical validation. …


Engineering Electrospun Pvdf Nanofibers For Next-Generation Wearable Bioelectronics, Reshmi Banerjee, Gymama Slaughter Jan 2026

Engineering Electrospun Pvdf Nanofibers For Next-Generation Wearable Bioelectronics, Reshmi Banerjee, Gymama Slaughter

Center for Bioelectronics Publications

Electrospun poly(vinylidene fluoride) (PVDF) and P(VDF-TrFE) nanofibers offer a mechanically flexible, high-surface-area platform for wearable bioelectronics, including piezoelectric sensing and self-powered operation. This review establishes a process–structure–property–performance framework for engineering electrospun PVDF- and P(VDF-TrFE)-based wearable systems. Relationships amongst precursor composition, electrospinning parameters, fiber morphology and alignment, crystalline phase formation, dipole orientation, and device-level piezoelectric performance are examined. Electrospinning is compared with other established fabrication methods including solution casting, spin coating, melt processing, phase inversion, and printing in terms of electroactive β-phase fraction, flexibility, scalability, manufacturing complexity, cost, and wearable-device suitability. Device architectures and performance are evaluated across pressure and strain …


Performance Assessment And Design Improvements For An Urban Coastal Detention Basin Under Intensifying Rainfall Extremes, Imiya Mudiyanselage Chathuranika, Agyare Asante, Faeghe Borhani, Xixi Wang, Mujde Erten-Unal, Dalya Ismael Jan 2026

Performance Assessment And Design Improvements For An Urban Coastal Detention Basin Under Intensifying Rainfall Extremes, Imiya Mudiyanselage Chathuranika, Agyare Asante, Faeghe Borhani, Xixi Wang, Mujde Erten-Unal, Dalya Ismael

Civil & Environmental Engineering Faculty Publications

Coastal urban areas are increasingly exposed to flooding driven by more frequent and intense rainfall events, rising sea levels, and expanding impervious surfaces. Norfolk, Virginia, a low-lying coastal city with aging stormwater infrastructure, faces heightened vulnerability to these hydrologic pressures. This study evaluates the hydraulic performance of an existing urban detention basin within the Edgewater–Larchmont catchment under 10-, 50-, and 100-year, 2-h design storms using the U.S. Environmental Protection Agency’s Storm Water Management Model (SWMM). Simulations were conducted for both pre- and post-development conditions to assess changes in peak discharge, storage capacity, and water level dynamics. Results show that urbanization, …


Optimizing Maintenance Routes For Highway Infrastructure Using Leader-Follower Autonomous Vehicles, Qing Tang, Chenxi Chen, Xianbiao Hu, Yuxin Ding, Tianjia Yang Jan 2026

Optimizing Maintenance Routes For Highway Infrastructure Using Leader-Follower Autonomous Vehicles, Qing Tang, Chenxi Chen, Xianbiao Hu, Yuxin Ding, Tianjia Yang

Civil & Environmental Engineering Faculty Publications

The Autonomous Truck Mounted Attenuator (ATMA), a leader–follower style connected and automated vehicle system, enhances safety during transportation infrastructure maintenance in work zones. However, the significantly lower speed of ATMA, compared to regular vehicles, causes moving bottlenecks that reduce roadway capacity and prolong queuing, leading to further delays. Different ATMA routes lead to varying patterns of time-dependent capacity drop, affecting the user equilibrium traffic assignment and resulting in differing system costs. This study aims to optimize ATMA routing within a network to minimize the system cost associated with its slow-moving operation. To this end, a queuing-based traffic assignment approach is …


Short-Term Response Mechanisms Of Water Quantity And Quality Of Daihai Lake Under Temperature-Driven Changes, Hao Zhang, Xiaohong Shi, Xianhua Li, Junping Lu, Ruizhong Gao, Xixi Wang, Shuhao Zhang, Longmei Xie, Yu Liu Jan 2026

Short-Term Response Mechanisms Of Water Quantity And Quality Of Daihai Lake Under Temperature-Driven Changes, Hao Zhang, Xiaohong Shi, Xianhua Li, Junping Lu, Ruizhong Gao, Xixi Wang, Shuhao Zhang, Longmei Xie, Yu Liu

Civil & Environmental Engineering Faculty Publications

Temperature-driven mechanisms involving complex feedback and lag that affect the evolution of hydrological processes and ecological functions in cold- and arid-region lakes represent a core scientific issue in current hydrology and lake ecology research. In this study, based on month-scale temperature and environmental factor data from Daihai Lake in Inner Mongolia from January to December 2023, statistical methods (redundancy analysis, Tukey's test analysis, correlation analysis, structural equation modeling), time series analysis methods (dynamic time warping), and machine learning methods (random forest) were combined. A hierarchical and phased response framework was constructed that encompassed driver identification, path tracing, lag characterization, and …


On The Contribution Of The Gulf Stream To High Frequency Coastal Sea Level Variability, Tal Ezer Jan 2026

On The Contribution Of The Gulf Stream To High Frequency Coastal Sea Level Variability, Tal Ezer

CCPO Publications

Long-term Atlantic Ocean and Gulf Stream (GS) variability were linked in past studies to coastal sea level (CSL) change along the U.S. East Coast - a weakening GS can lead to rise in CSL and increased coastal flooding. However, high frequency variability (HFV) in CSL is, in most cases, attributed to atmospheric weather events. This study is focused on HFV (intraseasonal variations with periods between similar to 1 week and similar to 2 months) in the GS and in CSL. First, wavelet and spectral analysis of observations of the Florida Current transport and CSL characterized the HFV in the data, …


Lessons For Transformative Ocean Science From The Integrated Marine Biosphere Research (Imber) Project, Deborah Santos Prado, Ella-Kari Muhl, Mia Strand, Derek Armitage, Nina Bednaršek, Stephanie Brodie, Christopher Cvitanovic, John Claydon, Sam Dupont, Karen Evans, Alistar Hobday, Eileen Hofmann, Raleigh Hood, Laura Kaikkonen, Dongyan Liu, Jessica Melbourne-Thomas, Franz Mueter, Eugene Murphy, Prateep Kumar Nayak, Alice Newton, Heidi Pethybridge, Carol Robinson, Samiya Selim, Rowan Trebilco, Micaela Trimble, Fang Zuo Jan 2026

Lessons For Transformative Ocean Science From The Integrated Marine Biosphere Research (Imber) Project, Deborah Santos Prado, Ella-Kari Muhl, Mia Strand, Derek Armitage, Nina Bednaršek, Stephanie Brodie, Christopher Cvitanovic, John Claydon, Sam Dupont, Karen Evans, Alistar Hobday, Eileen Hofmann, Raleigh Hood, Laura Kaikkonen, Dongyan Liu, Jessica Melbourne-Thomas, Franz Mueter, Eugene Murphy, Prateep Kumar Nayak, Alice Newton, Heidi Pethybridge, Carol Robinson, Samiya Selim, Rowan Trebilco, Micaela Trimble, Fang Zuo

CCPO Publications

This paper synthesizes the key contributions and lessons learned from Integrated Marine Biosphere Research (IMBeR), a large-scale global research project aimed at fostering ocean sustainability under global change for the benefit of society. The UN Decade of Ocean Science for Sustainable Development has catalyzed a renewed focus on the importance of transforming ocean science. IMBeR’s global activity over the past decade has focused on promoting transformative science by generating, mobilizing, and communicating the knowledge needed to support ocean governance. Key contributions from IMBeR participants include quantifying and comparing historic and present structure and functioning of linked ocean and human systems, …


End-To-End Modeling For The Ross Sea Region Marine Protected Area: A Review Of Available Tools For Conservation Objectives, James R. Lovvorn, Cara Nissen, Alexis A. Bahl, Erik Behrens, Cassandra M. Brooks, Katy Christensen, Michael S. Dinniman, Lilian A. Dove, Alice K. Duvivier, Eileen E. Hofmann, Hayley Kwasniewski, Young Shin Kwon, Sharon E. Stammerjohn, Lei Xing Jan 2026

End-To-End Modeling For The Ross Sea Region Marine Protected Area: A Review Of Available Tools For Conservation Objectives, James R. Lovvorn, Cara Nissen, Alexis A. Bahl, Erik Behrens, Cassandra M. Brooks, Katy Christensen, Michael S. Dinniman, Lilian A. Dove, Alice K. Duvivier, Eileen E. Hofmann, Hayley Kwasniewski, Young Shin Kwon, Sharon E. Stammerjohn, Lei Xing

CCPO Publications

The challenge of protecting marine ecosystems, including biodiversity and manifold interactions in changing environments, has encouraged development of end-to-end models linking physical drivers through entire food webs to upper-level predators. Ideally such models should have temporal and spatial resolution adequate to capture important small-scale processes, while including scales large enough to encompass local food webs and movements of wide-ranging consumers. The need for component submodels to be manipulated and upgraded independently by scientists from different disciplines, and used selectively depending on questions addressed, favors modular structure allowing linkage of different submodels with varying strengths and weaknesses. As an example, this …


Ecological Feedbacks In The Earth System, Eugene J. Murphy, Jessica J. Williams, Isla H. Myers-Smith, Vivienne P. Groner, David M. P. Jacoby, Lester Kwiatkowski, Jess Melbourne-Thomas, Emma Ransome, Cristina Banks-Leite, Laurent Bopp, Marion Gehlen, Eileen E. Hofmann, Babette Hoogakker, Nadine M. Johnston, Yadvinder Malhi, Emma L. Cavan Jan 2026

Ecological Feedbacks In The Earth System, Eugene J. Murphy, Jessica J. Williams, Isla H. Myers-Smith, Vivienne P. Groner, David M. P. Jacoby, Lester Kwiatkowski, Jess Melbourne-Thomas, Emma Ransome, Cristina Banks-Leite, Laurent Bopp, Marion Gehlen, Eileen E. Hofmann, Babette Hoogakker, Nadine M. Johnston, Yadvinder Malhi, Emma L. Cavan

CCPO Publications

Ecological feedbacks are fundamental features of the Earth system, affecting physical processes and chemical cycles. Our understanding of the interactions underlying these feedbacks at different spatial and temporal scales and the extent to which feedbacks affect Earth system functioning remains limited. Climate change and other anthropogenic pressures are already negatively affecting ecological processes in marine, freshwater, and terrestrial ecosystems. These will most likely be amplified in the coming decades under our current warming and socioeconomic pathways. The knock-on impacts on ecological feedbacks have the potential to cause rapid perturbations to the Earth system, and may significantly impact the structure and …


Basal Melting Variability Of The Ross Ice Shelf From Mixing Ratios Of Simulated Water Masses (1993-2018) And Potential Climatic Drivers, Enrico Pochini, Andrea Bergamasco, Florence Colleoni, Manuel Bensi, Giorgio Budillon, Pasquale Castagno, Michael S. Dinniman, Pierpaolo Falco, Emanuele Forte, Vedrana Kovačević, Stefanie L. Mack Jan 2026

Basal Melting Variability Of The Ross Ice Shelf From Mixing Ratios Of Simulated Water Masses (1993-2018) And Potential Climatic Drivers, Enrico Pochini, Andrea Bergamasco, Florence Colleoni, Manuel Bensi, Giorgio Budillon, Pasquale Castagno, Michael S. Dinniman, Pierpaolo Falco, Emanuele Forte, Vedrana Kovačević, Stefanie L. Mack

CCPO Publications

Several water masses circulate under the Ross Ice Shelf (RIS), the largest ice shelf in Antarctica, each causing basal melting with a specific spatio-temporal pattern. To investigate these patterns and their variability, we applied a mixing ratio analysis to simulated water masses from a new numerical ocean model of the Ross Sea. The simulation, which was run over 26 years (1993–2018) and which includes the RIS cavity, shows good agreement with seaborne and mooring observations. The total RIS basal melt rate is 90 Gt/yr on average, and is caused mostly by High Salinity Shelf Water (HSSW) (68%), which enters the …


Agricultural Productivity Under Energy Development: Insights From California, Wai Yan Siu, Sherzod B. Akhundjanov Jan 2026

Agricultural Productivity Under Energy Development: Insights From California, Wai Yan Siu, Sherzod B. Akhundjanov

ODU Articles

This paper examines how agricultural productivity patterns in Kern County, California, a leading region for both agricultural production and oil and gas development, co-vary with the spatial and temporal expansion of hydraulic fracturing and associated energy infrastructure. Using parcel- and county-level analyses, we characterize how agricultural productivity differs across proximity to energy development and across spatial scales. The results reveal spatially heterogeneous and scale-dependent patterns: parcel-level evidence indicates lower Enhanced Vegetation Index-based vegetation productivity within the 20-mile proximity zone around fracking wells, while county-level results show heterogeneous crop-specific yield changes during the post-expansion period. Together, these findings highlight the importance …


Seeing The Invisible Load: Xr+ Multimodal Sensing For Cognitive Ergonomics In Industrial Training, Jessica M. Johnson, Andwele Grant Jan 2026

Seeing The Invisible Load: Xr+ Multimodal Sensing For Cognitive Ergonomics In Industrial Training, Jessica M. Johnson, Andwele Grant

Virginia Digital Maritime Center (VDMC) Faculty Publications

Extended reality (XR) technologies are increasingly positioned as disruptive Industry 5.0 tools for human-centric industrial training and intelligent human–system integration. Coupled with multimodal sensing (eye tracking, EEG, HRV, GSR, and other physiological signals), XR environments promise to make otherwise invisible cognitive demands observable, especially for novice trainees entering complex industrial settings. Yet the evidence base is fragmented: (1) there is no quantitative synthesis of the cognitive ergonomics benefits of XR plus sensing; (2) little is known about which XR–sensor configurations yield the strongest effects; (3) prior reviews rarely focus on industrial and manufacturing tasks; (4) multimodal signals are used predominantly …


From Reviews To Value: Harnessing Crowdsourced Data To Capture Visitor Perceptions And Economic Benefits Of Recreation, Laura Costadone, Shan Zhang Jan 2026

From Reviews To Value: Harnessing Crowdsourced Data To Capture Visitor Perceptions And Economic Benefits Of Recreation, Laura Costadone, Shan Zhang

ODU Articles

Quantifying the recreational value of protected natural areas is essential for sustainable management, conservation financing, and informed decision-making. Traditional approaches, such as on-site surveys, are often costly, spatially limited, and constrained by regulatory barriers. This study evaluates the potential of crowdsourced user-generated data to jointly assess visitor perceptions and the economic value of nature-based recreation, using Back Bay National Wildlife Refuge (Virginia, USA) as a case study. We integrated georeferenced photographs and textual content from four platforms (Flickr, TripAdvisor, Yelp, and AllTrails) with supplementary survey data to analyze visitation patterns, visitor sentiment, cultural ecosystem services, and recreational value using the …


Autonomous Float Data Reveal Decoupled Trends In Chlorophyll And Stratification In The Indian Ocean, Marufa Ishaque, Sophie Clayton, John Klinck Jan 2026

Autonomous Float Data Reveal Decoupled Trends In Chlorophyll And Stratification In The Indian Ocean, Marufa Ishaque, Sophie Clayton, John Klinck

OES Faculty Publications

Recent studies have shown that the Indian Ocean is warming significantly, but how this warming impacts primary production is largely unresolved due to a relative lack of depth-resolved biological observations. In this study, we have used Biogeochemical-Argo data from 2013 to 2022, comprising over 9,000 individual profiles, to examine regional patterns and trends in depth-integrated chlorophyll, depth-integrated net primary production and stratification in the northern and Equatorial Indian Ocean. Our analysis shows that water column stratification is increasing in the majority of the study area, with the highest rate of increase observed in the western Bay of Bengal. At the …


Cybersecurity Center For Offshore Wind Energy (Final Project Round), Sachin Shetty Jan 2026

Cybersecurity Center For Offshore Wind Energy (Final Project Round), Sachin Shetty

Center for Secure and Intelligent Critical Systems (CSICS) Publications

This project establishes a Cybersecurity Center for Offshore Wind Energy with the objective of designing and operating a cyber-physical testbed for wind energy farms (WEFs) that enables comprehensive cybersecurity research. The testbed incorporates a Supervisory Control and Data Acquisition (SCADA) system connected to turbine models via industrial-grade programmable logic controllers (PLCs) and remote terminal units (RTUs). It supports side-channel data acquisition, implementation and analysis of various cyberattack scenarios, and development of attack detection, mitigation, and best-practice guidance tailored to wind energy systems. During the project, the team expanded the number and fidelity of mathematical turbine models (MTMs), integrated these models …


Impacts Of Segmenting Principle On Learner Performance And Attitude In A 3d Environment: A Mixed-Method Multiple Case Study, Kristin Herman, Mohan Yang, Jim Shifflet, Noah Glaser Jan 2026

Impacts Of Segmenting Principle On Learner Performance And Attitude In A 3d Environment: A Mixed-Method Multiple Case Study, Kristin Herman, Mohan Yang, Jim Shifflet, Noah Glaser

STEMPS Faculty Publications

This study presents a conceptual replication of Moreno’s (Appl Cogn Psychol 21:765–781. 10.1002/acp.1348, 2007) study on the benefits of adhering to the segmentation principle when utilizing multimedia learning objects. Furthermore, this study expands upon the original by taking place in a low-immersive virtual reality environment, allowing for further understanding on the extent to which multimedia principles are still relevant. Both a synchronous and an asynchronous case are presented. Results indicate benefits for both cases in far transfer of learning. Furthermore, synchronous learners indicated a significant reduction in cognitive load and increased overall attitudes towards learning due to segmented instruction.


Drafting Policy To Address Academic Integrity: The Other Ai In Education, Elizabeth Burns Jan 2026

Drafting Policy To Address Academic Integrity: The Other Ai In Education, Elizabeth Burns

STEMPS Faculty Publications

The article focuses on the role of school librarians in drafting policies to address academic integrity amid the increasing use of artificial intelligence (AI) in K-12 education. It defines AI, including generative AI (GenAI), and discusses both the challenges and opportunities AI presents for teaching and learning, emphasizing the need for clear guidelines on ethical use. The article outlines three common AI policy models—permissive, hybrid, and restrictive—and stresses the importance of collaboration between librarians and teachers to establish consistent expectations, promote critical thinking, and ensure proper attribution of AI-generated content. School librarians are positioned as key facilitators in guiding students …


Students-Generative Ai Interaction Patterns And Its Impact On Academic Writing, Jinhee Kim, Sang-Soog Lee, Rita Detrick, Jialin Wang, Na Li Jan 2026

Students-Generative Ai Interaction Patterns And Its Impact On Academic Writing, Jinhee Kim, Sang-Soog Lee, Rita Detrick, Jialin Wang, Na Li

STEMPS Faculty Publications

Considering both the transformative opportunities and challenges presented by generative AI (GenAI) in academic writing, effectively integrating GenAI into the academic setting becomes a significant need requiring prioritization. Yet, there is limited understanding regarding the nature of interactions between different types of students, what behavioral patterns students exhibit during a student-GenAI interaction (SAI) on a given task, and how these different SAI patterns relate to the actual writing task performance. This study, therefore, aimed to identify SAI patterns of academic writing tasks depending on students’ level of AI literacy and examine the differences in academic writing performance between the identified …


A Comparison Of Conversational Chatbots And The Internet For Consumer Information Search, Wondwesen Tafesse, Yoseph Mamo Jan 2026

A Comparison Of Conversational Chatbots And The Internet For Consumer Information Search, Wondwesen Tafesse, Yoseph Mamo

STEMPS Faculty Publications

This study compares consumer perceptions of conversational chatbots and the internet for information search. While the internet is a mature platform, conversational chatbots represent an emerging technology, and insight into how consumers view them in relation to the internet for information search is lacking. Drawing on the information source utility perspective, the study builds a comparative model based on four key dimensions: information currency, information customisation, information trustworthiness, and media richness. Additionally, the study investigates consumers’ prior experience with conversational chatbots as a moderating factor. Data was collected from 191 respondents recruited through MTurk. Paired sample t-tests assessed mean differences …


Crossing The Theory Threshold: The Pedagogical Potential Of Generative Artificial Intelligence In Educational Research, Amanda Burbage, Jennifer L. Styron Jan 2026

Crossing The Theory Threshold: The Pedagogical Potential Of Generative Artificial Intelligence In Educational Research, Amanda Burbage, Jennifer L. Styron

EVMS School of Health Professions Faculty Publications

Purpose

This paper presents findings from an educational research graduate course in which generative artificial intelligence (AI) was incorporated to strengthen learners' understanding of threshold concepts related to theoretical frameworks. Medical and health professionals often struggle with the transition from a clinical role into the educational research role.

Methods

The study posits that the use of generative AI will help learners understand and apply theoretical frameworks beyond a superficial level, furthering their understanding, constructing new knowledge, and strengthening their ability to develop sound educational research studies. Journal and AI transcripts were analyzed for 37 participants.

Results

Open-ended codes were grouped …


Lessons Learned From Clinical Trials Of Thymic Stromal Lymphopoietin (Tslp) Inhibition, Jonathan Corren, Larry Borish, Christopher Brightling, Joseph K. Han, Emma Guttman-Yassky, Steven Ziegler, Jean Publicover, Jyotsna Gulati, Nestor Molfino, Christopher S. Ambrose, Jean-Pierre Llanos, Lang Chen, Jane R. Parnes, Joseph Spahn, Andrew Lindsley Jan 2026

Lessons Learned From Clinical Trials Of Thymic Stromal Lymphopoietin (Tslp) Inhibition, Jonathan Corren, Larry Borish, Christopher Brightling, Joseph K. Han, Emma Guttman-Yassky, Steven Ziegler, Jean Publicover, Jyotsna Gulati, Nestor Molfino, Christopher S. Ambrose, Jean-Pierre Llanos, Lang Chen, Jane R. Parnes, Joseph Spahn, Andrew Lindsley

Department of Otolaryngology (ENT) Faculty Publications

Type 2 (T2) immune–mediated epithelial-driven diseases are characterized by dysregulated immune responses at epithelial barrier surfaces. A key mediator of these diseases is thymic stromal lymphopoietin (TSLP), an epithelial cytokine that acts as a regulator of both T2 and non-T2 inflammation. TSLP activates dendritic cells and other immune cells, promoting the release of proinflammatory cytokines, including IL-4, IL-5, and IL-13. Given its central role in initiating and amplifying T2 inflammation, TSLP has emerged as a promising therapeutic target in multiple epithelial-driven inflammatory diseases. Tezepelumab is a human monoclonal antibody that selectively blocks TSLP from interacting with its receptor complex, thereby …


Defining Clinically Meaningful Within-Patient Changes In Heart Failure: Jacc Heart Failure Position Statement, Amin Yehya, Rebecca Hahn, Barry Borlaug, Victoria Delgado, Andrew Ambrosy, Ross Arena, Nosheen Reza, Gregory Lewis, Natalie Tapaskar, Salvatore Carbone, Cynthia Chauhan, Mitchell A. Psotka, Norman Stockbridge, James Januzzi, Javed Butler, Jennifer Cowger, Biykem Bozkurt, John Spertus Jan 2026

Defining Clinically Meaningful Within-Patient Changes In Heart Failure: Jacc Heart Failure Position Statement, Amin Yehya, Rebecca Hahn, Barry Borlaug, Victoria Delgado, Andrew Ambrosy, Ross Arena, Nosheen Reza, Gregory Lewis, Natalie Tapaskar, Salvatore Carbone, Cynthia Chauhan, Mitchell A. Psotka, Norman Stockbridge, James Januzzi, Javed Butler, Jennifer Cowger, Biykem Bozkurt, John Spertus

Department of Medicine Faculty Publications

Heart failure (HF) clinical trials increasingly rely on diverse endpoints beyond mortality, including hospitalizations, imaging, hemodynamic status, biomarkers, functional capacity, and patient-reported outcomes. Although statistically significant differences between treatment groups are commonly reported, interpreting whether these changes are clinically meaningful for individual patients remains challenging. This JACC: Heart Failure position statement proposes a pragmatic framework for defining clinically meaningful within-patient change across commonly used HF outcomes by integrating measurement variability, prognostic associations, and patient-anchored evidence where available. Relative and absolute risk reductions should both inform interpretation of clinical events, while imaging, hemodynamic, biomarker, and functional measures require changes exceeding measurement …


Automation And Autonomy In The Ivf Laboratory: Concepts And Implications For Embryologists, Jacques Cohen, Gerardo Mendizabal-Ruiz, Giles Anthony Palmer, Giuseppe Silvestri, Mina Alikani Jan 2026

Automation And Autonomy In The Ivf Laboratory: Concepts And Implications For Embryologists, Jacques Cohen, Gerardo Mendizabal-Ruiz, Giles Anthony Palmer, Giuseppe Silvestri, Mina Alikani

EVMS School of Health Professions Faculty Publications

Automation is regarded as the next phase in the evolution of laboratory IVF. Despite technological advances, most laboratory procedures remain operator-dependent, contributing to variability in performance and outcomes. While automation has improved reproducibility and efficiency in many areas of medicine, its adoption in IVF has been slow. This review examines how automation may be integrated into IVF laboratories through a set of conceptual distinctions. Automation refers to the execution of procedural steps by machine-controlled systems, whereas autonomy describes the degree to which such systems can operate without human intervention. This review distinguishes between static automation, which maintains or monitors the …


Element-Based Predictive Modeling Of Hydrothermal Liquefaction Bioproducts Derived From Corn Stover, Isamu Umeda, Meicen Liu, Yi Zheng, Jiefu Wang, Zhiwu Wang, Sandeep Kumar Jan 2026

Element-Based Predictive Modeling Of Hydrothermal Liquefaction Bioproducts Derived From Corn Stover, Isamu Umeda, Meicen Liu, Yi Zheng, Jiefu Wang, Zhiwu Wang, Sandeep Kumar

Civil & Environmental Engineering Faculty Publications

The hydrothermal liquefaction (HTL) process offers an energetic advantage over pyrolysis because it does not require prior drying of the biomass feedstock. However, there are significant challenges in simultaneously estimating both the yields and characteristics of products from the HTL of biomass with theoretical support. This study developed a unique element-based kinetic model to predict the yields, higher heating values, and fuel characteristics of solid residue and heavy bio-oil, based on the temperature, residence time, solid loading, and elemental composition (C, H, N, and O) of corn stover. Furthermore, the model predicted the weights of dissolved carbon and nitrogen in …


Harnessing Activated Sludge For The Treatment Of Hydrothermal Liquefaction Wastewater: A Proof-Of-Concept Study, Cyrus Li, Jiefu Wang, Meicen Liu, Yi Zheng, Sandeep Kumar, Isamu Umeda, Chandan Mahata, John Norton Jan 2026

Harnessing Activated Sludge For The Treatment Of Hydrothermal Liquefaction Wastewater: A Proof-Of-Concept Study, Cyrus Li, Jiefu Wang, Meicen Liu, Yi Zheng, Sandeep Kumar, Isamu Umeda, Chandan Mahata, John Norton

Civil & Environmental Engineering Faculty Publications

Although hydrothermal liquefaction (HTL) is the leading technology in converting wet biomass into bioenergy, the treatment of its toxic-laden aqueous phase wastewater presents a major challenge on its path toward commercial viability. This study presents the first-ever assessment of sewage sludge-fed HTL wastewater (SS-HTLWW) treatment and toxic compound removal using municipal activated sludge (AS) by optimizing its cultivation condition. It was found that AS with optimized pretreatment can remove up to 91.2% of the soluble chemical oxygen demand (sCOD) in SS-HTLWW, of which up to 82% can be attributed to biological mineralization and adsorption of sCOD by AS. Conventional bioprocess …


Nonstationary Spatial Correlation Of Earthquake Ground Motions In California, Pengfei Wang, Busra Bocekli, Junhui Yang, Scott J. Brandenberg, Jonathan P. Stewart Jan 2026

Nonstationary Spatial Correlation Of Earthquake Ground Motions In California, Pengfei Wang, Busra Bocekli, Junhui Yang, Scott J. Brandenberg, Jonathan P. Stewart

Civil & Environmental Engineering Faculty Publications

Assessing seismic risk to spatially distributed infrastructure systems requires realistic representations of spatially correlated ground motions. Existing models for the spatial correlations of ground motions rely on strong second-order stationarity assumptions, under which the correlation structure is assumed to be invariant across space, potentially masking regional variations. Because repeatable site and path effects can vary spatially, the resulting correlation structure is likely to be nonstationary. We propose a nonstationary spatial correlation method that captures geographically varying correlation decay behavior. We compute site-to-site Pearson correlations of within-event residuals using earthquakes recorded at both sites in each site pair and model the …


When Slides Replace Thinking: How Powerpoint Culture Undermines Conceptual Learning In Engineering Education, Shahin Nayyeri Amiri, Hamid Eisazadeh Jan 2026

When Slides Replace Thinking: How Powerpoint Culture Undermines Conceptual Learning In Engineering Education, Shahin Nayyeri Amiri, Hamid Eisazadeh

Civil & Environmental Engineering Faculty Publications

Engineering education has gradually shifted from deep conceptual teaching to a culture dominated by presentation slides. In many universities today, core courses such as Statics, Dynamics, and Mechanics of Materials are taught through PowerPoint files rather than through reasoning, derivation, and problem solving. While slide-based instruction may appear efficient, it encourages passive learning and has severely weakened students’ ability to think independently and make sound engineering judgments. Traditionally, these fundamental courses were taught by seasoned instructors who had mastered the subjects and took genuine pride in explaining complex ideas with clarity and passion. They guided students through the logic behind …


Nature-Based Solutions For Urban Resilience And Environmental Justice In Underserved Coastal Communities: A Case Study On Oakleaf Forest In Norfolk, Va, Farzaneh Soflaei, Mujde Erten-Unal, Carol L. Considine, Faeghe Borhani Jan 2026

Nature-Based Solutions For Urban Resilience And Environmental Justice In Underserved Coastal Communities: A Case Study On Oakleaf Forest In Norfolk, Va, Farzaneh Soflaei, Mujde Erten-Unal, Carol L. Considine, Faeghe Borhani

Civil & Environmental Engineering Faculty Publications

Climate change and sea-level change (SLC) are intensifying flooding in U.S. coastal communities, with disproportionate impacts on Black and minority neighborhoods that face displacement, economic hardship, and heightened health risks. In Norfolk, Virginia, sea levels are projected to rise by at least 0.91 m (3 ft) by 2100, placing underserved neighborhoods such as Oakleaf Forest at particular risk. This study investigates the compounded impacts of flooding at both the building and urban scales, situating the work within the framework of the UN Sustainable Development Goals (UN SDGs). A mixed-method, community-based approach was employed, integrating literature review, field observations, and community …


Multi-Isotope Tracing Reveals Nitrate And Sulfate Sources And Fate Across Contrasting Activity Zones In A Semi-Arid Basin Of Northern China, Chang Yue, Ruizhong Gao, Limin Duan, Tianke Su, Xixi Wang, Tingxi Liu, Guoqiang Wang Jan 2026

Multi-Isotope Tracing Reveals Nitrate And Sulfate Sources And Fate Across Contrasting Activity Zones In A Semi-Arid Basin Of Northern China, Chang Yue, Ruizhong Gao, Limin Duan, Tianke Su, Xixi Wang, Tingxi Liu, Guoqiang Wang

Civil & Environmental Engineering Faculty Publications

In semi-arid surface water-groundwater systems, nitrate (NO₃–) and sulfate (SO₄²–) are jointly influenced by natural processes and anthropogenic activities, yet how their sources, transformations, and export vary across contrasting activity zones remains insufficiently understood. Integrating hydrochemistry, multiple stable isotopes, a Bayesian isotope mixing model, and representative-section flux analysis, this study investigated the source compositions, transformation processes, and export differences of NO₃– and SO₄²– in the Dahei River Basin.   New hydrological insights for the region: Results showed greater SO₄²– enrichment in high-activity zones, whereas NO₃– exceedance was more prominent in low-activity zones. In …


Resilient Built Environment: An Overview On Design Strategies For Coastal Adaptation To Sea Level Rise, Farzaneh Soflaei, Gelareh Abdolzadeh, Navid Ziaee, Mohammad Amin Jafari, Faeghe Borhani Jan 2026

Resilient Built Environment: An Overview On Design Strategies For Coastal Adaptation To Sea Level Rise, Farzaneh Soflaei, Gelareh Abdolzadeh, Navid Ziaee, Mohammad Amin Jafari, Faeghe Borhani

Civil & Environmental Engineering Faculty Publications

This paper delves into the escalating risks faced by urban coastal communities due to tidal and storm flooding, exacerbated by climate change-induced Sea Level Rise (SLR). Projections indicate a potential increase in sea levels by at least 3 feet by 2100, with historical data revealing an average annual rise of 1.2-1.7 mm since the 1900s. With over 300 million individuals inhabiting coastal areas, low-lying regions emerge as particularly vulnerable to the impacts of SLR. This accelerated rise amplifies the significant challenge of nuisance flooding, a local-scale issue aggravated by high tide and winds, leading to inundation, road closures, infrastructure deterioration, …