Physical Sciences and Mathematics Commons^™

Synthesis Of N And C Nucleosides Via Cycloaddition Reactions A New Approach To An Old Problem, Glenn L. Heise

Dissertations

No abstract provided.

Regioselectivity In The Cyclization Of Delta, Epsilon-Epoxy Esters, William F. Prout

Dissertations

No abstract provided.

Effect Of Polymerization Conversion On The Experimental Determination Of Monomer Reactivity Ratios In Copolymerization, Sevim Zeynep Erhan

Dissertations

In this study the comparison of the methods used to calculate monomer reactivity ratios from experimental copolymer composition data is targeted.

For this purpose, nine samples of each of nine different concentrations of styrene-methyl methacrylate monomer mixtures were prepared. These mixtures were then polymerized for different times ranging from one to nine hours and the percent conversion to copolymer was determined.

The compositions of these copolymers were determined by their refractive index increments measured in two different solvents. Ultraviolet absorption spectroscopy was also studied as a possible method to find copolymer compositions. Though this method has been used previously, UV …

Investigation Of The Synthesis And Polymerization Behavior Of Vinyl Benzoate, Selim Mehmet Erhan

Dissertations

The goal of this study is to present a method that gives higher conversions and molecular weights for the polymerization of vinyl benzoate than obtained in previous investigations.

Polyvinyl benzoate has benzene rings attached to the backbone chain, therefore is hard and rigid. This is a characteristic which has a large application area. However previous studies in polymerizing vinyl benzoate with bulk and solution polymerizations reported low yields and troublesome crosslinking, which has limited its application. Emulsion polymerization method has the advantage of giving high polymerization rates together with high molecular weights, and therefore was chosen as the method for …

Molecular Properties Of Cetiedil And Its Interactions With Human Erythrocytes, Chakravarthy Narasimhan

Dissertations

No abstract provided.

Naphthalene-2,3-Dialdehyde: A Synthon To 7,9-Polymethylene-8h-Cyclohepta[B]Naphthalene-8-One And A Study Of Their Aromaticity, Edward O. Crapps

Dissertations

This report describes the synthesis of naphthalene-2,3-dialdehyde, and an analytical method for determining its purity by thin layer chromatography. Subsequently, the dialdehyde was condensed with various cyclic ketones to generate a series of polymethylene bridged naphthotropones. It was found that planarity and aromaticity increase with the size of the methylene bridge, although, the bridge must contain six or more methylene groups for the latter to be true. The claim for aromaticity is supported by NMR and IR data, which indicates the positive charge for a perchlorate cation salt is delocalized over the naphthalene and tropone ring system. Furthermore, from the …

Kinetics And Mechanism Of Acylation Of Amines With 2-Naphthoyl Azide, Abraham L. Faburada

Dissertations

The reaction of 2-naphthoyl azide with primary and secondary amines in protic and aprotic solvents follows second-order kinetics. The effect of increasing solvent polarity is shown to increase the rate of reaction. For amines of similar basicity, the rate of reaction decreases with increasing steric hindrance on the amine. The changes in free energy and entropy of activation for n-butylamine and cyclohexylamine are in accord with steric requirements of amines. For amines of similar steric hindrance, the rate of reaction increases with increasing amine basicity. The mechanism of addition-elimination involving the formation of a tetrahedral intermediate is consistent with the …

Kinetics Of Ternary Complex Formation Reactions Of The Nickel(Ii) Complexes Of Ethylenediaminediacetate And Triethylenetetramine With Bidentate Donors, Lawrence H. Kolopajlo

Dissertations

The stopped-flow technique was used to measure rate constants for ternary complex formation involving both NiEDDA and Ni(trien)('2+), and bidentate donors. The reactions of both NiEDDA and Ni(trien)('2+) with bipy, phen, en, and sar were studied. In addition the reaction of NiEDDA and gly was studied. The reactions were of the first-order with respect to either nickel complex, and with respect to enH('+), bipy, and phen. The reactions involving phen and bipy were independent of pH and were reversible. The formation rate constants for the systems containing diamine reactants are as follows:

(DIAGRAM, TABLE OR GRAPHIC OMITTED...PLEASE SEE DAI)

For …

Determination Of Organophosphorus Compounds By Hplc With Post-Column Photochemical Degradation Followed By The Formation Of Reduced Heieropolymolybdate, Stephen R. Priebe

Dissertations

A novel method for the determination of organophosphorus (OP) compounds by HPLC with post-column photochemical and chemical derivatization reactions has been developed. The OP compounds eluted from the column were photochemically degraded to orthophosphate by the use of a 450 W xenon lamp in conjunction with an auxiliary photodegradation reagent. The photodegradation reaction was studied extensively by means of batch irradiations with triethylphosphate as a model compound. The effects of the initial concentrations of triethylphosphate and ammonium peroxydisulfate, and of varying the pH of the reaction medium were determined. A survey of potential interferences was performed. Copper(II) ion was found …

Micellarly Catalyzed Reaction Of Substituted Benzohydroxamic Acids, Nop Utrapiromsuk

Dissertations

The rate constants for hydrolysis of ten derivatives of benzohydroxamic acid, namely, p-H, p-CH(,3), m-CH(,3), p-CH(,3)CH(,2), p-OCH(,3), p-NO(,2), p-Cl, and m-Cl, in 0.160 and 0.158 M HCl at 67.9-68.2(DEGREES)C without and with sodium 1-dodecanesulfonate were determined. There is a good linear correlation between log k(,w) and the Hammett substituent constants, (sigma), for all para and meta derivatives where k(,w) is the rate constant in the bulk aqeous phase. In the presence of micelles all the compounds, except the meta-nitro derivative, followed the standard pseudophase model of micellar catalysis. However, correlations of log k(,m) or log K/N, where k(,m) is the …

Stereochemistry And Circular Dichorism Of Some Cobalt(Iii) Complexes With Ethylenediamine-N, N’-Diacetic Acid And N, N'-Dimethylethylenediamine-N ,N'-Diacetic Acid, Godfrey Chinenye Mbah

Dissertations

Two series of complexes trans-{Co(LL')EDDA}('+) and trans-{Co(LL')DMEDDA}('+), LL' = Meen, 2-Mepn, udmeen, sdmeen, R-dmepn were prepared. EDDA was reacted with cobalt(II) carbonate and the resulting solution combined with the diamine of choice. For the DMEDDA complexes the ligand DMEDDA was first prepared by adding neutralized chloroacetic acid to sdmeen and precipitating out the ligand as the barium salt. The DMEDDA complexes were prepared by reacting the barium salt first with cobalt(II) sulfate and then with the diamines listed above except udmeen. The DMEDDA complexes with R-pn were also prepared. For both series the oxidation of the Co(II) to Co(III) was …

Preparation And Properties Of Benzotropones And Benzohomotropones, Robert E. Suder

Dissertations

No abstract provided.

Proximity Effects. Kinetics, Mechanisms And Reactivity Correlations For The Acidic And Alkaline Hydrolysis Of Ortho-Substituted-N-Methylbenzohydroxamic Acids, Irl E. Ward

Dissertations

No abstract provided.

The Effect Of Stabilizing Groups On The Extent Of Long-Range Π Electron Participation And The Effect Of The Negative Charge On The Chemical Shift Of Neighboring Protons In Carbanions, Atilla Tuncay

Dissertations

No abstract provided.

A Study Of Selected Variables For Prediction Of Success And Placement In General Chemistry At Western Michigan University, Stephen M. Yekeson

Dissertations

Chapter I

The Problem

Introduction

The traditional philosophy that a college-or a university is an exclusive institution in which only highly selected individuals receive a concentrated training in the traditional liberal arts no longer exists. In America, for instance, as early as 1870, Harvard, the colonial college with a narrow curriculum, was transformed rather rapidly into a modern university with many new subjects and the elective system (Garrett, 1949). Also, since 1642, when the first entrance requirements were instituted for American higher education, a continuing debate has developed over what constitutes a sound curriculum for education. There are those who …

A Stereochemical Study Of Some 2,2'-Bridged Biphenyls, Alan J. Quarfoot

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No abstract provided.

Asymmetric Induction In Grignard Reactions In A Chiral Solvent, John E. Davis

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No abstract provided.

Triplet-Triplet Energy Transfer In Indolylketones, Larry E. Hewitt

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No abstract provided.

The Effect Of Stereoelectronic Control And Long Range Interaction On The Stability Of Bicyclic Enolate Anions, Edwin M. Van Dam

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No abstract provided.

The Wittig Reaction With Carbohydrates And The Addition Of Benzenesulfonyl Azides To Indoles, George R. Wellman

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No abstract provided.

Stereochemistry And Circular Dichroism Of Trans-Diacidobisdiamine Complexes Of Cobalt(Iii), Jack A. Tiethof

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No abstract provided.

A Study Of The Mechanism Of The Ligand Exchange Between Triethilenetetraminenickel(Ii) And 1,10-Phenanthroline, James Allan Boersma

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No abstract provided.

Cell-Free Amino Acid-Incorporating Systems From Mesofhilic And Thermophilic Species Of The Genus Bacillus, Nisson Schechter

Dissertations

No abstract provided.

The Reaction Of Acetaldehyde With Some Cobalt (Iii) Complexes Containing Coordinated Glycine, James C. Dabrowiak

Dissertations

No abstract provided.

Part I. The Stereochemistry Of Carbanions Formed By Base Catalyzed Decomposition Of Azoacetates Part Ii. Anomalous Decarbonylation Of 4 –Substituted Carboxylic Acids With Thionyl Chloride, Tai-Shun Lin

Dissertations

Introduction

Although the stereochemical capabilities of carbonium ions have been extensively investigated, the stereochemical fate of carbanions has been subjected relatively little to systematic scrutiny. The fact that only a limited number of clean-cut sources of carbanions are available has added difficulty to such investigations.

The stereochemical capabilities of carbanions has been extensively and thoroughly examined in recent years by Cram and coworkers. However, the carbanion carbon developed in the reactions employed was bonded in every case to an unsaturated (usually aromatic) group. No fully aliphatic carbanion has been subjected to such a stereochemical study.

The reaction of lead tetraacetate …

The Synthesis And Photolysis Of Kreysiginone And The Syntheses And Antibacterial Activity Of 1-Vinyl-3,4-Dihydroisoquinoline Methiodides, Bruce L. Jensen

Dissertations

No abstract provided.

Dimethyl Sulfoxide Oxydation Of Hydroxy-Steroids And Studies On The Oxidation Of The 5’–Hydroxy Group Of Nucleosides, Carmen V. Zenarosa

Dissertations

Introduction

In our earlier work we demonstrated the usefulness of the acidcatalyzed reaction between N-(p -tolyl)diphenylketenimine (21) and dimethyl sulfoxide (DMSO) for the oxidation of secondary alcohols. This was exemplified by the oxidation of 2',3'-O-isopropylideneadenosine and other secondary alcohols.¹ We have now extended this procedure to the oxidation of hydroxy-steroids.

Alkynylamines or ynamines can be written in two resonance forms: R-C≡C-N R'₂ and R-C=C=NR'₂. Because of the close similarity between the latter structure and the structure of a ketenimine (R₂C=C=N-R') and the ability of sulfoxide-ketenimine to effect the oxidation of secondary alcohols, we …

Homogenous Catalytic Hydrogenation Of Organic Compounds Using Rhodium-Triarylphosphine Complexes, Jack Lee Parsons

Dissertations

Introduction

The purpose of this research was to study the homogeneous catalytic hydrogenation of α,β-unsaturated organic compounds containing a wide variety of reducible functional groups. The catalysts to be used were rhodium complexes of triarylphosphines. It was also desired to develop these catalytic systems into practical synthetic methods for the reduction of unsaturated compounds.

Electrolyte Equilibria In Blood, Edward J. Fitzsimons

Dissertations

No abstract provided.

A Study Of The Electromotive Force Developed In Grignard Solutions, Frank P. Cassaretto

Dissertations

No abstract provided.