Veterinary Medicine Commons^™

Comparison Between Surgical And Non-Surgical Treatments Of Concomitant Cranial Cruciate Ligament Rupture And Medial Patellar Luxation In Small-Breed Dogs, Ekkapol Akaraphutiporn, Chalika Wangdee, Irin Kwananocha

The Thai Journal of Veterinary Medicine

Cranial cruciate ligament rupture (CrCLR) and medial patellar luxation (MPL) are common problems that cause hindlimb dysfunction, lameness and pain in dogs. Although surgical intervention is recommended for these conditions, it may not be suitable for an individual with some underlying diseases. The objective of the present study was to compare the outcomes between surgical and non-surgical treatments for concomitant CrCLR and MPL in small-breed dogs. Seven stifles from five small-breed dogs with concomitant CrCLR and MPL were enrolled and divided into two groups. Four limbs (three dogs) in Group 1 were treated conservatively, and three limbs (two dogs) in …

Development Of A Preliminary Clinical Approach For Detecting Insulin Resistance For Normoglycemic Control In Canine Diabetes, Chutirat Torsahakul

The Thai Journal of Veterinary Medicine

Consistent and effective blood glucose (BG) control is crucial in the treatment of diabetes mellitus (DM) and insulin resistance (IR). In this study, the surrogate indices for monitoring insulin sensitivity and the preliminary clinical approach for detecting IR were established. Fasting serum C-peptide was measured by a commercial enzyme-linked immunosorbent assay (ELISA) kit and utilized as an endogenous insulin representation. The homeostasis model assessment of insulin resistance (HOMA-IR) was then calculated. To detect the IR, the relationship between HOMA-IR and fasting serum C-peptide in each individual subject was analyzed, and designed cut-off values. The results revealed that the HOMA-IR of …

Progestin-Based Non-Surgical Contraception In Dogs And Cats: A National Survey Of Practices Among Thai Veterinarians, Shanaporn Leelakajornkit, Piyaporn Kamdee, Suppawiwat Ponglowhapan

The Thai Journal of Veterinary Medicine

This cross-sectional study aimed to assess the current use of progestins as contraceptives in dogs and cats and to evaluate veterinarians' awareness of related complications across Thailand. A total of 724 veterinarians participated, predominantly female (66.3%) and aged 31-40 years (49.6%), with most working in Bangkok and its metropolitan area (52.6%) and having 6-15 years of experience in small animal practice (46.4%). Approximately 6.8% of respondents (49/724) reported using injectable progestins, mainly in female dogs (87.8%) and cats (83.7%), but also in male dogs (18.4%) and cats (14.3%). Veterinarians using progestins were mostly male (59.2%), with an average age of …

Effect Of Modified Smart Extender On Sperm Longevity And Frozen-Thawed Semen Quality In Bantam Chicken (Gallus Gallus), Nattaporn Chaysakul, Naruephon Leeamnuaycharoen, Marvin Bryan Salinas, Teepakorn Lertwichaikul, Chakorn Kunkaew, Jureerat Sumretprasong, Anucha Sathanawongs

The Thai Journal of Veterinary Medicine

The round body shape and short legs of Bantam chickens (Gallus gallus) pose breeding challenges, making artificial insemination critical for these animals. To contribute to such assisted reproductive technology in avians, this study assessed the effect of a modified simple medium for assisted reproductive technology (SMART) extender on sperm longevity and frozen-thawed semen quality compared to the Blumberger Hahnen Sperma Verdünner (BHSV) extender. Sperm motility and viability were measured in 20 roosters at fresh and chilled conditions at 4-, 24-, and 48-hour intervals. For the subsequent freezing step, 6% and 9% DMA were added to both extenders as …

Morphological And Morphometric Variations Of The Tympanic Bulla Between Domestic Shorthair And Brachycephalic Cats Utilizing Computed Tomography, Naparee Srisowanna, Damri Darawiroj, Nan Choisunirachon, Chutimon Thanaboonnipat, Sirinun Pisamai Tabtieang

The Thai Journal of Veterinary Medicine

Tympanic morphology of the dogs was reported to be varied due to the characteristics of the skull types. The small tympanic bulla is normally seen in brachycephalic dogs. However, this variation in narrowed-skull shaped cats has not been unveiled yet. The objective of this study was to describe the tympanic morphology of cats between brachycephalic and domestic shorthair (DSH) cats. Computer tomography (CT)-skull images of 15 domestic shorthair cats and 11 brachycephalic cats were evaluated for tympanic dimension on transverse and dorsal planes and the tympanic bone thickness. All parameters were compared between both groups. The results revealed that all …

Research Progress On The Structure And Function Of The Main Glycoproteins Of Bovine Infectious Rhinotracheitis Virus, Xin Zhang, Ruizhen Jian, Weijuan Jia, Yunjiao Chen, Qinglei Meng, Fang Yang, Jianjian Han, Zhilin Liu, Zelin Jia, Jiayu Cui, Xueli Wang

The Thai Journal of Veterinary Medicine

Infectious bovine rhinotracheitis (IBR) is an acute, febrile, and contact infectious disease. Bovine infectious rhinotracheitis is endemic in China and even the world, which not only restricts the development of the cattle industry but also brings significant economic losses to farms. Infectious bovine rhinotracheitis virus (IBRV) contains 25 - 33 structural proteins, of which glycoproteins gB, gC, gD, gE, gG, gH, gI, gK, gL, and gM are the major structural glycoproteins of bovine rhinotracheitis virus, and all of these glycoproteins are interconnected with the assembly, invasion, release, and replication of the virus, and the only glycoproteins that are known …

A Systematic Literature Review Of Granulocytes-Colony Stimulating Factor Treatment In Animals, Syahirah Ahmad Affandi, Nurul Hayah Khairuddin, Mohammed Sadiq Babatunde, Azalea Hani Othman, Collin Looi Seng Kim, Siti Sarah Othman, Sharifah Roohi Syed Waseem Ahmad

The Thai Journal of Veterinary Medicine

This study presents a systematic literature review (SLR) on the efficacy of granulocytes-colony stimulating factor (G-CSF) as a treatment component in relation to clinicopathological parameters and overall outcomes. Using the PICO approach, a research question development tool, the SLR was designed to identify the animals in which G-CSF had been used, the types of G-CSF utilized and their effectiveness as a therapeutic agent in stimulating haematological parameters, as well as their potential adverse effects. Three primary keywords associated with the review topic were selected and incorporated into the search query to retrieve pertinent literature from three databases: Scopus, Science Direct, …

Outcomes In Dogs Undergoing Surgical Correction For Septic Peritonitis: A Retrospective Study In 61 Cases (2019-2022), Krishaporn Kradangnga, Naipaporn Kongrattanachat, Wichulada Suwansukroj, Jiraporn Supasombatolan, Chayanon Tiaraksa

The Thai Journal of Veterinary Medicine

This retrospective study described clinical parameters, evaluated the chance of death (hazard ratio) and compared outcomes until hospital discharge in septic peritonitis dogs that underwent surgery in 61 cases at a single academic referral hospital population. The surgical records of 223 dogs with suspected septic peritonitis requiring surgical intervention were reviewed and a total of 61 dogs, primarily mixed breed (34.43%), with intraoperative gross lesions and cytology confirmed septic peritonitis were included in the study. The gastrointestinal tract was the most common source of septic peritonitis (52.46%). The overall survival to hospital discharge was 52.46%. Admission time until surgery, drain …

Ultrasonic Doppler As A Guide For Feline Peripheral Arterial Catheterization, Satoshi Haginoya, Elizabeth J. Thomovsky, Hsin-Yi Weng, Paula A. Johnson, Aimee C. Brooks

Purdue University Libraries Open Access Publishing Fund

Objectives

The study aimed to determine if an ultrasonic Doppler-guided technique (UDGT) leads to improved placement efficacy (time, success) of feline dorsal pedal arterial catheters vs the traditional palpation-guided technique (TPT).

Methods

A total of 26 adult, client-owned cats requiring sedation or general anesthesia for any reason, aged >12 months and weighing >3.0 kg, and with Doppler blood pressure measurements of at least 80 mmHg were enrolled. Each hindlimb was randomly assigned for dorsal pedal arterial catheterization using either the UDGT or TPT. With the UDGT, the location of the artery was identified by an audible sound using the Doppler. …

Reproduction And In Vitro Technologies Of Swamp Buffalo; Past, Present, And Future, Ruchikon Jongsuwanwattana, Theerawat Swangchan-Uthai, Sudson Sirivaidyapong

The Thai Journal of Veterinary Medicine

Swamp buffalo (Bubalus bubalis carabanensis) has long been integral to agriculture and has served as an essential source of food security in Southeast Asia, particularly in Thailand. Despite their economic and cultural significance, swamp buffaloes have been at risk of declining populations due to low fertility rates. This review provides a comprehensive overview of swamp buffalo reproduction, examining past and present practices, identifying gaps in the literature, and exploring potential future directions for improving reproductive efficiency. This examination inquiries into the reproductive anatomy and physiology of the domestic buffalo, providing a comparative analysis among ruminants. Recent advancements in …

An Accidental Discovery Of Ductal Adenocarcinoma Of The Pancreas In An Adult Horse With Severe Abdominal Pain, Thita Wonghanchao, Kanokpan Sanigavatee, Chanoknun Poochipakorn, Onjira Huangsaksri, Phudit Maneesaay, Rungrueang Yodsheewan, Metha Chanda

The Thai Journal of Veterinary Medicine

A native pony, eight years old and male, was tentatively diagnosed with abdominal pain and treated immediately. Sequential hematological profiles revealed increased levels of aspartate aminotransferase (AST), alkaline phosphatase (ALP), and creatinine, as well as reduced albumin. After the pony's death, which occurred eight days after treatment began, a necropsy was performed. The liver's external surface showed small foci, but no gross lesion was observed in the pancreas, which was enlarged. Haematoxylin and eosin (H&E) staining of the liver showed multifocal inflammation in the hepatic parenchyma, coinciding with bile duct hyperplasia. The pancreas H&E staining showed well-differentiated tubular glands with …

A Conjunctival Mast Cell Tumor In Golden Retriever: A Case Report, Orapun Jaturakan

The Thai Journal of Veterinary Medicine

A high-grade mast cell tumor of the conjunctiva in the Golden Retriever is a rare condition. Wide excisional conjunctival mass biopsy is suggested, combined with chemotherapy. A 9-year-old neutered female Golden Retriever with a painless conjunctival mass at the right temporal bulbar conjunctiva was presented at the Ophthalmology Clinic of the Small Animal Teaching Hospital, Faculty of Veterinary Sciences, Chulalongkorn University. Complete physical and ophthalmic examinations were performed. The metastasis of the primary conjunctival mass was investigated by radiography of the skull, orbit, thorax, and abdomen, as well as by ultrasonography in the orbit and abdomen. No metastasis was confirmed …

Cervical Lymphangiosarcoma In A Poodle Dog: Surgical Treatment And Chemotherapy, Minkyung Kim, Young-Hwan Kim, Jae-Eun Hyun

The Thai Journal of Veterinary Medicine

A 7-year-old neutered male Poodle exhibited a persistent caudoventral cervical mass with draining lesions characterized by chronic and relapsing features. Upon presentation, the mass measured 7 × 11 × 11.5 cm, containing sanguine fluid. Computed tomography revealed the diffuse extension of the cervical mass from the C3 level to the thoracic inlet, affecting the sternal lymph node. Extensive surgical removal was attempted with meticulous resection to avoid damaging the right jugular vein, carotid sheath, and vagus nerve within the mass. Histopathology and immunohistochemical staining for factor VIII confirmed the diagnosis of lymphangiosarcoma. Due to inadequate surgical margin excision, four cycles …

Food Safety, Swine Health, And Productivity Of A Farrow-To-Finish Swine Farm Following Implementation Of A Certified Haccp System In Japan, Hiroshi Akaike, Makoto Nagai, Tomomitsu Alexandre Okatani, Sumalee Boonmar, Yukio Morita

The Thai Journal of Veterinary Medicine

This study examined the safety and productivity of a farrow-to-finish swine farm from 2015 to 2019, in Japan. The farm implemented a farm Hazard Analysis and Critical Control Points (HACCP) system in July 2016. The critical control point was “the selection of shipping pigs” and the critical limit for preventing contamination with residual antibiotics in pigs was “the withholding period has passed,” while that for preventing contamination with residual needle fragments was “the needle was not included.” No deviations from critical limits were observed, indicating the pigs were safe. In addition, the numerical goal of pigs born alive per litter …

A Preliminary Study Of Tracheal Morphology In Mixed-Breed Dog Cadavers: Anatomical Variation Of Tracheal Cartilaginous Rings, Naparee Srisowanna, Sirin Theerawatanasirikul, Sukumal Prukudom, Niyada Lansubsakul, Montri Pattarapanawan, Maneenooch Khiao-In

The Thai Journal of Veterinary Medicine

Anatomical abnormalities of the trachea leading to respiratory distress. Few reports describe the morphological characterization of the dog’s trachea, particularly in the tracheal cartilaginous rings. In this study, twelve tracheas from mixed-breed dog cadavers were obtained to investigate their features across three anatomical tracheal regions: cervical, thoracic inlet, and intrathoracic trachea. The average length of the trachea was 18.92 ± 0.67 cm. Each trachea contained a different number of tracheal rings, ranging from 32 to 41 rings (37.42 ± 0.81 rings). A significant reduction in both outer transverse diameter (OTD) and outer vertical diameter (OVD) was observed from the cervical …

First Serological Evidence Of Coxiella Burnetii And Mycobacterium Avium Subspecies Paratuberculosis (Map) Among Deer In An Institutional Farm In Malaysia, Bura Thlama Paul, Faez Firdaus Abdullah Jesse, Shivnraj Sundar Universiti Putra Malaysia, Nur Hanis Nadhirah Yosryhan, Yonis Ahmed Ahmed Jimale Dr, Eric Lim Teik Chung Dr, Mohd Azmi Mohd Lila Prof

The Thai Journal of Veterinary Medicine

Q fever is a zoonotic disease caused by Coxiella burnetii, which is associated with reproductive disorders such as abortion and reproductive problems in ruminants, while paratuberculosis is an underdiagnosed disease caused by Mycobacterium avium paratuberculosis (MAP) which causes chronic wasting, low fertility, and mortality in ruminants. Although both C. burnetii and MAP infections have been reported in domestic ruminants worldwide, there is no data on their seroprevalence status among deer in Selangor, Malaysia. This study investigated the seroprevalence status of C. burnetii and MAP among deer in Malaysia. Ninety-two blood sera collected from an institutional deer farm were screened …

Multidrug-Resistant Esbl-Producing Escherichia Coli Coexisting With Colistin-Resistance Genes In Pig Farms, Central Thailand, Wipawee Songsaeng, Nutthee Am-In, Nuvee Prapasarakul, Wandee Sirichokchatchawan

The Thai Journal of Veterinary Medicine

The presence of extended-spectrum beta-lactamase and colistin resistance E. coli in food-producing animals is a public health concern. This study was conducted using a rigorous methodology to survey the prevalence of ESBL-producing and colistin-resistant E. coli from pig farms in the central part of Thailand. A total of 519 samples were collected from fecal, feed, and waste in 53 farms located in central Thailand. All samples were inoculated onto selective agar, and species identification was performed using biochemical assays and MAlDI-TOF MS. Antimicrobial susceptibility was determined by broth microdilution, and ESBL production was confirmed by the combination disc diffusion method. …

A Preliminary Study Of Lasia Spinosa Thw. Feed Supplementation Improving Semen Quality Of Subfertile Purebred Boars, Supitcha Kaewma, Junpen Suwimonteerabutr, Nutthee Am-In, Saritvich Panyaboriban, Mongkol Techakumphu, Theerawat Swangchan-Uthai

The Thai Journal of Veterinary Medicine

Poor semen quality is a significant issue among imported purebred boars in Thailand, affecting both semen quality itself and reducing productivity at AI stations. The present study investigated the effects of dietary supplementation with Lasia spinosa Thw. (LST) on improving boar semen quality. A group of boars experiencing poor semen quality were monitored, and three were selected due to their persistent low semen profiles for the supplementation experiment. Dried LST powder was prepared in small bags at a dosage of 4 g per 100 kg body weight and added to the regular feed for daily oral administration over an 8-week …

Quantitative Evaluation Of Different Fixatives For Masson Trichrome Staining In Canine Intestinal Tissue: An Image Analysis-Based Comparative Study, Siriluck Juntausa, Kongkiat Srisuwatanasagul, Kittipot Kongsonthana, Punnarat Vibulchan, Sayamon Srisuwatanasagul

The Thai Journal of Veterinary Medicine

Neutral buffer formalin (NBF) has been widely used as a fixative for histological staining for ages. However, for some special staining, such as Masson trichrome staining, it has been proposed that the suitable fixative was Bouin’s solution. The purpose of the present study was to compare the different fixatives and post-fixative protocols on the quality of Masson trichrome staining. The canine intestines (n = 10), which were the duodenum and colon, were used as the candidate organs since they comprised of various tissue components. The fixatives and staining protocols were divided into four groups, which were Groups 1 and 2; …

Preventing And Managing Equine Gastric Ulcer Syndrome, Kylie Bell, Karl Hoopes

All Current Publications

Current industry trends regarding equine management practices largely contribute to the development of equine gastric ulcer syndrome (EGUS). Research on effective medical management exists; however, we lack studies on the efficacy of equine-welfare-minded solutions. This fact sheet reviews current literature, including diagnosing, treating, and preventing EGUS. It also provides a general overview of the natural equine, promoting a greater understanding of the connection between strategies to prevent and manage EGUS.

Intradermal Vaccination With A Phytoglycogen Nanoparticle And Sting Agonist Induces Cytotoxic T Lymphocyte-Mediated Antitumor Immunity, Juan F. Hernandez-Franco, Imran M. Jan, Bennett D. Elzey, Harm Hogenesch

Purdue University Libraries Open Access Publishing Fund

A critical aspect of cancer vaccine development is the formulation with effective adjuvants. This study evaluated whether combining a cationic plant-derived nanoparticle adjuvant (Nano-11) with the clinically tested STING agonist ADU-S100 (MIW815) could stimulate anticancer immunity by intradermal vaccination. Nano-11 combined with ADU-S100 (NanoST) synergistically activated antigen-presenting cells, facilitating protein antigen cross-presentation in vitro and in vivo. Intradermal vaccination using ovalbumin (OVA) as a tumor antigen and combined with Nano-11 or NanoST prevented the development of murine B16-OVA melanoma and E.G7-OVA lymphoma tumors. The antitumor immunity was abolished by CD8+ T cell depletion but not by CD4+ T cell depletion. …

Intraluminal Tracheal Stenting In Dog With Tracheal Collapse : A Case Report, Ratiporn Tantisak, Siriluck Luckanahasaporn, Ardong Atiptamvaree, Tamolwan Anyamaneecharoen, Kamonchanok Lamsaman, Suphat Soeratanapant, Poondej Charunmethee

The Thai Journal of Veterinary Medicine

A 12-year-old female neutered dog was referring to the pet hospital for the chief complaint of syncopic episodes 3 times/day. The dog had history of severe goose-honking non-productive cough and tachypnea. The dog got worsen despites medical management was consist of antibiotic, mucolytic, bronchodilator, glucocorticoids and nebulization. The dog was not response to medication then develop to apnea due to obstructive breathing. The radiographs diagnosis from private clinic was redundant trachea with narrowing intrathoracic trachea. The surgical treatment was considered. The tracheobronchoscopy was confirmed Tracheal collapse at mid cervical to cranial thoracic part. Stenting was a treatment options in life-threatening …

Application Of Metoclopramide As Gastroprokinetic In Koi Carp (Cyprinus Carpio) With Positive Buoyancy Disorders, Pornpawit Tanpichai, Thanaboon Katechaimongkol, Patharapol Piamsomboon, Thanida Haetrakul

The Thai Journal of Veterinary Medicine

A two-year-old Koi carp or fancy carp (Cyprinus carpio) with a symptom of recurrent positive buoyancy was admitted to the Veterinary Medical Aquatic Animal Research Center of Excellence (VMARCE), Faculty of Veterinary Science, Chulalongkorn University. Radiographic examination with positive contrast media revealed gas accumulation in the gastrointestinal tract without obstruction; subsequently, idiopathic intestinal pseudo-obstruction was suspected. The anti-flatulence drug simethicone was administered, but the fish did not respond to the treatment. Therefore, metoclopramide, as the medical trial at a dosage of 0.5 mg/kg, was intramuscularly injected once daily for four consecutive days. The fish convalesced with neutral buoyancy …

Cardiac Biomarkers For Monitoring Canine Heartworm Disease: A Comparative Study Of N-Terminal Pro B Type Natriuretic Peptide And Cardiac Troponin I Levels, Sariya Asawakarn, Kittipong Tachampa, Piyanan Taweethavonsawat

The Thai Journal of Veterinary Medicine

Canine heartworm disease is a global mosquito-borne parasitic illness that affects dogs. The main species of filarids responsible for this disease is Dirofilaria immitis. This article specifically explores the use of cardiac biomarkers, such as N-terminal pro B type natriuretic peptide (NT-proBNP) and cardiac troponin I (cTnI), for diagnosing and monitoring canine heartworm disease. These biomarkers can indicate myocardial injury and heart failure, particularly in chronic infections. The study compares the levels of NT-proBNP and cTnI in dogs with heartworm disease, both clinically diagnosed cases and those without symptoms. The results reveal that cTnI is elevated in both cases, …

Quantitative Assessment Of Preoperative And Postoperative Brachycephalic Airway Obstruction Syndrome Surgery Using Clinical Grading Questionnaires And 6-Minute Walk Test In French Bulldogs, Tamolwan Anyamaneecharoen, Krishaporn Kradangnga, Saikaew Sutayatram, Pasakorn Brikshavana, Sumit Durongphongtorn

The Thai Journal of Veterinary Medicine

Brachycephalic airway obstructive syndrome (BAOS) is an anatomical abnormality of the upper airway commonly found in brachycephalic breeds, leading to clinical signs and physical capacity impairment. The degree of stenotic nares was reported to be related to BAOS severity in French bulldogs. This study aimed to compare clinical signs and physical capacity in French bulldogs before and after BAOS surgery using modified Roedler questionnaires and a 6-minute walk test (6-MWT). Twenty-seven French bulldogs were enrolled in this study (non-BAOS control (n=7), non-severe stenotic nares BAOS dogs (n=8), and severe stenotic nares BAOS dogs (n=12). BAOS surgery included staphylectomy using bipolar …

Conventional Vs Three-Dimensional Computed Tomography For Measurement Of Tibial Tuberosity To Trochlear Groove Distance In Small Breed Dogs With And Without Medial Patellar Luxation, Radka S. Garnoeva

The Thai Journal of Veterinary Medicine

The operative technique for medial patellar luxation (MPL) is dependent on the degree of accompanying bone deformities. The most frequent abnormalities: the shallow trochlear groove and tibial tuberosity medialisation are corrected surgically with trochleoplasty and tibial tuberosity transposition, respectively. The aim of the present study was to determine the distance between the tibial tuberosity and the trochlear groove (TT-TG) on two-dimensional axial computed tomography (CT) scans and three-dimensional multiplanar reconstruction images from 21 stifles from healthy dogs and 15 stifles from dogs with grade 2 MPL and to compare the performance of both methods. Two axial CT scans of the …

Seroprevalence Of Lawsonia Intracellularis Antibodies Among Large-Scale Swine Farming Systems In Thailand, Thanh Che Nguyen, Chairani Ridha Maghfira, Nathaya Young, Kanokwan Samatiwat, Chaiyan Kaewpaluk, Apisak Laothanakit, Pawarisa Mungprasittichai, Roongroje Thanawongnuwech, Yaowalak Panyasing

The Thai Journal of Veterinary Medicine

Gastrointestinal infectious diseases caused by bacteria have been a major problem in the swine industry, including Thailand. Porcine proliferative enteropathy (PPE), also known as porcine ileitis, is an enteric infectious disease caused by Lawsonia intracellularis – an obligate intracellular bacterium. PPE has been an economic threat to the global pork production system due to various types of diarrheas. Serological diagnosis can be applied to the seroprevalence of pathogen-antibodies and the timing of L. intracellularis infection when introduced to the herd. This present study showed the current serological status and the seroprevalence of antibodies against L. intracellularis in large-scale Thai swine …

Investigation Of P27 Tumor Suppressor Gene (Cdkn1b) Polymorphisms In Dogs With Malignant Mammary Tumors, Gizem Kırmızıoğlu, Iraz Akış

The Thai Journal of Veterinary Medicine

Mammary tumors are the most common neoplasm in dogs, with a high mortality rate. The development of canine mammary tumors (CMT) is multifactorial, but different incidence rates between breeds suggest the effects of genetic risk factors. Many CMT-associated candidate genes were reported, mainly involved in cell cycle control. This study aims to investigate p27 tumor suppressor gene polymorphisms in dogs with mammary tumors and analyze the association between variations and CMTs. For this purpose, case and control groups were formed from 22 dogs diagnosed with malignant mammary tumors and 10 dogs with healthy mammary glands. The whole canine p27 gene …

Preventive Effects Of Quercetin On The Leaky Gut By Suppression Of Il-1beta-Induced Transcription Factors Involved In An Inflammatory Pathway In Colonic Epithelial Cells, Wannaporn Chayalak, Sumpun Thammacharoen, Chatsri Deachapunya, Sutthasinee Poonyachoti

The Thai Journal of Veterinary Medicine

Flavonol quercetin (Q), found in vegetables and fruits, demonstrates the most potent anti-inflammatory effect. The preventive effect and cellular mechanisms of Q (Q1, Q10, and Q100 µM) on IL-1β induced leaky gut via the signaling molecules of inflammatory pathway, NF-κB p65-iκB/or p38/ERK1/2/MLCK/phospho(p)-MLC were investigated in Caco-2 cells. The cytotoxic effect of Q was initially determined by MTT assay. Transepithelial electrical resistance (TER) and apical-to-basolateral fluorescein isothiocyanate-labeled dextran (FD-4) flux were used to determine paracellular permeability. The protein expression of signaling molecules was examined by Western blot analysis, and their target MLCK mRNA expression was determined using real-time PCR. All Q …

Impacts Of Species, Gender Disparities, And Covid-19 Lockdowns On Population Control: Insights From 337,590 Dogs And Cats In Bangkok Metropolitan Administration (Bma), Thailand (2009-2023), Shanaporn Leelakajornkit, Natchanon Dumniem, Permsak Wataganara, Siwa Maison, Suppawiwat Ponglowhapan

The Thai Journal of Veterinary Medicine

Surgical sterilization stands as a key solution to address the overpopulation of dogs and cats, with numerous influencing factors impacting the success of population control efforts, including species, gender, and financial conditions. The emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), or COVID-19, in 2020 has significantly altered human life and impacted pet animals. Lockdown restrictions were implemented in various countries, including Thailand, affecting the cumulative data of neutered animals, which was subsequently analyzed in this study. There were 337,590 dogs and cats from 2009 to 2023, and the data were systematically categorized by years, species, and gender. …