Veterinary Medicine Commons^™

Replacing Steam-Flaked Corn And Dry Rolled Corn With Condensed Distillers Solubles In Finishing Diets, Alex H. Titlow, Adam L. Shreck, Stephanie A. Furman Furman, Karla Jenkins, Matt K. Luebbe, Galen E. Erickson

Nebraska Beef Cattle Reports

The interaction between corn processing method and condensed distillers solubles (CDS) was evaluated using either steam-flaked corn (SFC) or dry rolled corn (DRC). As CDS replaced corn at either 15 or 30% of the diet DM, DMI intake decreased quadratically for both SFC and DRC. Within DRC- based diets, ADG increased quadratically with 15% CDS being greatest and F:G improved quadratically with 30% inclusion being best. When SFC was used as the grain source, ADG increased linearly and F:G improved quadratically with increasing levels of CDS. A greater performance response was observed with SFC compared to DRC when feeding increased …

The Effect Of Lameness On Average Daily Gain In Feedlot Steers, Giselle T. Kruse, Richard R. Randle, Douglas E. Hostetler Hostetler, Gary K. Tibbetts, Dicky D. Griffin, Kathryn J. Hanford, Terry Klopfenstein, Galen E. Erickson, Brandon L. Nuttelman, David R. Smith

Nebraska Beef Cattle Reports

The objective of this study was to test the effects of lameness on average daily gain (ADG) of feedlot steers. We evaluated two feedlot health data sets: 1) 14,798 steers from a 14-year period (1993 to 2006) at the Meat Animal Research Center (USDA MARC) near Clay Center, Neb.; and 2) 16,766 steers from an 8-year period (2002 to 2009) at the University of Nebraska Agricultural Research and Development Center (ARDC) near Mead, Neb. The ADG for USDA MARC steers with lameness late in the feeding period (≥ 60 days) was 0.04 lb./day less than steers without lameness. The ADG …

Including Next Enhance® Essential Oils In Finishing Diets On Performance With Or Without Rumensin® And Tylan®, Curtis J. Bittner, Galen E. Erickson, Karla Jenkins Jenkins, Matt K. Luebbe, Troy Wistuba

Nebraska Beef Cattle Reports

Finishing cattle performance was evaluated using NEXT ENHANCE essential oils in finishing diets. Treatments consisted of 1) control (CON), 2) NEXT ENHANCE at 300 mg/day (NE), 3) Rumensin and Tylan at 360 and 90 mg/day, respectively (RT), or 4) NEXT ENHANCE plus Rumensin and Tylan (NERT). No NEXT ENHANCE by Rumensin/Tylan interaction was observed. Steers fed Rumensin/Tylan had decreased F:G and increased live final BW and marbling score. The prevalence of liver abscesses decreased 46% when steers were fed Rumensin/Tylan. Including NEXT ENHANCE in finishing diets did not impact performance or carcass characteristics.

The Effect Of Commensal Microbial Communities On The Fecal Shedding Of Shiga Toxin-Producing E. Coli (Stec) In Beef Cattle, Nirosh D. Aluthge, Yoshitha A. Wanniarachchi, Brandon L. Nuttelman Nuttelman, Cody J. Schneider, Terry Klopfenstein, Galen E. Erickson, Jayne E. Stratton, Samodha C. Fernando

Nebraska Beef Cattle Reports

This ongoing study compares the gut microbial community composition between shedding steers high in shiga toxin-producing E. coli (STEC) counts and low-shedding steers. Shedders were identified among 170 beef animals over three time periods using selective microbiological culture media. The isolated bacterial cultures were confirmed to be STEC using PCR, 16s rRNA sequencing and a shiga toxin immunoassay. The most abundant strains found in the cattle feces were those belonging to the serogroups O111 (40.3%) and O157:H7 (37.3%), with O103 (8.3%), O26 (6.0%), O83 (4.5%), and O55 (3.0%) being detected in much lower numbers . Out of the 52 animals …

Hormonal Residues In Feedlot Pens And Runoff, Terry L. Mader, Leslie J. Johnson, Shannon L. Bartelt-Hunt Hunt, Daniel D. Snow, William L. Kranz, Charles A. Shapiro, Simon Van Donk, David P. Shelton, David Tarkalson, Tian Zhang

Nebraska Beef Cattle Reports

Two identically designed trials were conducted in separate years at the University of Nebraska Haskell Agricultural Laboratory, Concord, Neb., using 192 crossbred heifers (96/trial). Within a trial, heifers were assigned randomly to 2 groups (3 pens/group): 1) treatment (TRT) animals were administered synthetic hormones via subcutaneous implants (Ralgro and Revalor-H) and fed Melengesterol Acetate (MGA), or 2) control (CON) animals with no synthetic hormone provided.

Gains and feed conversions were 18.8 and 7.5% better, respectively, for TRT, while CON had 16.7% greater choice and prime carcasses. In runoff samples, progesterone was greater for CON. With the exception of androsterone, average …

Anaerobic Digestion Of Finishing Cattle Manure, Andrea K. Watson, Galen E. Erickson, Terry Klopfenstein Klopfenstein, Samodha C. Fernando, Jana L. Harding

Nebraska Beef Cattle Reports

Utilizing manure from cattle fed distillers grains in anaerobic digesters improved methane production and DM degradation of manure compared to manure from cattle fed no distillers grains. Manure from cattle fed in open lot pens had soil contamination which decreased OM content and led to decreased total methane production (L/day), but not when expressed as methane/g OM. If ash buildup is avoided, open lot manure can be used as anaerobic digester feedstock.

Effect Of Development System On Heifer Performance And Primiparous Heifer Grazing Behavior, Adam F. Summers, T. L. Meyer, Jacqueline Musgrave Musgrave, Stetson P. Weber, Rick N. Funston

Nebraska Beef Cattle Reports

The effect of heifer development system on primiparous heifer performance grazing corn residue during late gestation was investigated. Weaned heifers grazing corn residue tended to have reduced final BW after corn residue grazing compared to heifers grazing winter range. However reproductive performance for the two treatments was similar. When grazing corn residue as pregnant heifers during late gestation, heifers developed on corn residue had improved ADG compared to drylot-developed heifers and tended to have increased ADG compared to winter range-developed heifers. Adaptation to corn residue grazing as a developing heifer improves primiparous heifer performance grazing corn residue during late gestation.

Evaluation Of A New Chemistry For Rangeland Grasshopper Control, Jeffrey Bradshaw, Karla Jenkins, Sean Doyle Whipple Whipple, Rick Patrick

Nebraska Beef Cattle Reports

A grasshopper control study was conducted to evaluate the effectiveness of a new class of systemic chemical. The new pesticide Prevathon^® (high and low levels) was compared to Coragen^®, Dimilin^®, and a nontreated check. Grasshoppers were numerically reduced the most by Coragen and Prevathon, though not significant. The highest level of Prevathon did not numerically impact beneficial insects in general. Biomass and forage quality were not significantly impacted by chemical treatment. However, forage biomass was numericallygreatest for the highest level of Prevathon. Prevathon appears to be an acceptable systemic pesticide for grasshopper control with minimal …

Cutaneous Asthenia (Ehlers–Danlos Syndrome) In A Cat, Banu Dokuzeylül, Eli̇f Demet Altun, Tamer Hali̇t Özdoğan, Hasan Hakan Bozkurt, Seçki̇n Serdar Arun, Mehmet Erman Or

Turkish Journal of Veterinary & Animal Sciences

Ehlers-Danlos syndrome (EDS), or dermatosparaxis, is a rare hereditary disease of the connective tissue, which is characterized by skin hyperextensibility and laxity. In the present article, the case of a crossbred female spayed cat, at the age of 2 years, was presented with hyperelasticity of the skin, alopecia, and an ulcerative wound on the left hind leg. The animal's dorsum was hyperextensible, smooth to the touch, and could be easily torn with minor traumas. To the best of the authors' knowledge, the present report is the first documented feline case of cutaneous asthenia in Turkey.

Current Therapeutic Approaches To Equine Protozoal Myeloencephalitis, L. Dirikolu, Jonathan H. Foreman, Thomas Tobin

Maxwell H. Gluck Equine Research Center Faculty Publications

Equine protozoal myeloencephalitis is the most important infectious neurologic disease of horses in the Western Hemisphere. Equine protozoal myeloencephalitis can interfere with a horse's ability to race, work, and perform; untreated, EPM can be lethal. Antemortem diagnosis of EPM is challenging, requiring careful evaluation of the animal's history, clinical signs, and laboratory data, with rigorous exclusion of other causes.

Therapeutic approaches to EPM are evolving. First-generation therapeutic approaches for EPM were based on the classic anti–Toxoplasma gondii pyrimethamine–sulfonamide combinations; treatment is prolonged and can be associated with a considerable relapse rate, which may be associated with the difficulty in …

Formation Of The Plexus Sacralis In Pheasants (Phasianus Colchicus Mongolicus) And Macroanatomic Investigation Of The Nerves Originating From The Plexus Sacralis, Fati̇h Ramazan İstanbullugi̇l, Hüseyi̇n Karadağ, Şami̇l Sefergi̇l, Nazan Gezer İnce, Hasan Alpak

Turkish Journal of Veterinary & Animal Sciences

The purpose of this study was to investigate the formation of the plexus sacralis in the Kyrgyz pheasant (Phasianus colchicus mongolicus) and the origin of the nerves emerging from the plexus sacralis. Five adult male Kyrgyz pheasants were used that had been hunted in their natural habitat near the town of Tokmok in the Chuy region of Kyrgyzstan. The plexus sacralis was found to be formed in the lumbar region by the ventral strands of sacral nerves 1 to 5, originating in the spinal cord. The plexus is composed of the truncus cranialis, which consists of the ventral strands of …

Epibulbar Melanocytoma In A Goat, Annahita Rezaie, Hannaneh Golshahi, Mohammad Rahim Haji Hajikolaie

Turkish Journal of Veterinary & Animal Sciences

Melanocytoma is a benign tumor arising from the melanocytes. A 2-year-old female crossbreed goat that was suffering from respiratory insufficiency, emaciation, depression diffuse corneal opacity, and anemia was euthanized. There was a mass on the dorsal interface of the cornea and sclera of the left eye. It was raised, dark, and 2 mm in diameter. The histopathologic evaluation revealed melanocytoma and immunolabeling for Melan-A was positive. According to gross and microscopic evaluations, epibulbar melanocytoma was diagnosed and the authors think that the present case is the first recorded case of epibulbar melanocytoma in a goat.

Comparative Evaluation Of Liquid-Phase Blocking Elisa And Solid-Phase Competition Elisa Methods For The Detection Of Antibodies To The Structural Proteins Of Foot-And-Mouth Disease Types O And A Viruses, Murat Şevi̇k, Fahri̇ Ferudun Öztürk

Turkish Journal of Veterinary & Animal Sciences

In this study, we compared 2 methods, liquid-phase blocking ELISA (LPBE) and solid-phase competition ELISA (SPCE), for the detection of antibodies to the structural proteins of foot-and-mouth disease virus (FMDV). These methods were compared using sera collected from cattle (n = 30) without a history of foot-and-mouth disease infection or vaccination, cattle (n = 180) vaccinated with oil-adjuvanted bivalent vaccine, and international reference sera (positive, weak positive, and negative) for FMDV serotypes O and A. The results showed that SPCE had a better specificity (96.67% for serotype O and 100% for serotype A) than LPBE (90% for serotype O and …

The Protective And Therapeutic Effect Of Phenoxy-2-Methyl-2-Propionic Acid On Experimental Fatty Liver In Rats, Ümmügülsüm Gümüş, Gülbi̇n Şennazli, Utku Bakirel

Turkish Journal of Veterinary & Animal Sciences

In this study, the potential protective and therapeutic effect of phenoxy-2-methyl-2-propionic acid (PMPA) was investigated in rats with experimental hepatic steatosis induced by a carbon tetrachloride and paraffin liquid mixture (1:1). Forty Wistar albino rats were allocated to 4 groups with 10 rats in each. Group 1 was administered a saline solution; group 2 was administered the carbon tetrachloride and paraffin liquid mixture; group 3 was administered the carbon tetrachloride and paraffin liquid mixture and PMPA for 7 days; and in group 4, hepatic steatosis was created with the carbon tetrachloride and paraffin liquid mixture during the first 7 days, …

Effects Of Vacuum Packaging On The Quality Of Frozen Cooked Döner Kebab, Enver Bariş Bi̇ngöl, Funda Yilmaz, Karlo Muratoğlu, Kami̇l Bostan

Turkish Journal of Veterinary & Animal Sciences

Döner kebab is a traditional Turkish dish, recognized worldwide. It is an important fast-food meal sold by its local name in many countries. Döner kebab is consumed as a fresh dish and should be served immediately after cooking. Raw döner kebab can be stored by freezing, but there is not enough knowledge about the storage of cooked döner kebab. This study was conducted to investigate the effect of vacuum packaging on the meat quality of frozen cooked döner kebab. Packaged döner kebabs were stored at -18 ± 1 °C for up to 12 months and examined monthly for microbiological (total …

Prevalence Of Shiga Toxin-Producing Escherichia Coli And Pathogenic Leptospira Spp. In Rodents From Outdoor Farms In Western Spain, Alfredo Garcia, Remigio Martinez, Lourdes Garcia, Jose Manuel Benitez-Medina, David Risco, Waldo Luis Garcia, Joaquin Rey, Juan Manuel Alonso, Angeli Kodjo

Turkish Journal of Veterinary & Animal Sciences

Sixty-five rats (Rattus norvegicus) and 5 mice (Mus musculus) were trapped from 8 outdoor farms and the presence of Shiga toxin-producing Escherichia coli was not detected in any individual. Nevertheless, using the microscopic agglutination test, it was found that 20% (13/65) of rat serum samples were positive for anti-Leptospira antibodies, and DNA of pathogenic leptospires was detected in 3.07% (2/65) of the rat kidneys by real-time polymerase chain reaction. The most common infecting serovar was Castellonis (7.69%), followed by Canicola (6.15%) and Mangus (6.15%). According to these results, rats from outdoor farms may be considered a reservoir host for Leptospira …

Development Of A Subunit Vaccine Against Bovine Diarrhea Caused By K99 Enterotoxigenic Escherichia Coli And Bovine Viral Diarrhea Virus, Emad Hashish

Electronic Theses and Dissertations

Bovine diarrhea is economically one of the most important problems in cattle industry. Enterotoxigenic Escherichia coli (ETEC), particularly strains expressing K99 (F5) fimbriae and heat-stable type I (STa) enterotoxin is the predominant bacterial cause of diarrhea in calves; whereas bovine viral diarrhea virus (BVDV) causes diarrhea and other illness to cattle at all ages. A vaccine that prevents against both K99 fimbrial ETEC and BVDV could benefit greatly to cattle producers worldwide. We hypothesized that a novel multivalent vaccine composed of K99, STa and BVDV E2 antigens could induce immunity for broad protection against bovine diarrhea. In this study we …

Cytotoxicity Of Nickel Ions For Human Osteoblasts In The Context Of Orthodontic Treatment In Humans And Animals, Marcin Mikulewicz, Katarzyna Chojnacka, Iwona Kochanowska, Agnieszka Dziewicka, Maciej Janeczek, Jerzy Cieplik, Aleksander Chrószcz

Turkish Journal of Veterinary & Animal Sciences

In the present work, the biocompatibility of orthodontic devices was tested by the propagation of human osteoblasts. A different methodological approach was applied. Since the materials used in human and veterinary orthodontics (not in implantology) had been tested, osteoblasts were not implanted on the surface of the biomaterial, but have been cultured in the medium containing the products of corrosion. In the present work, osteoblasts were propagated in the medium spiked with Ni(II) salt versus the control. Osteoblast cells (live, dead, and total) were counted under light microscope. The statistical significance of the differences between the experimental and control groups …

The Effects Of Propofol And A Diazepam/Alfentanil Combination In Dogs Aged 10 Years And Above On Heart Rate, Respiratory Rate, Pulse Oximetry Data, Intraocular Pressure, And Body Temperature, Özlem Güzel, Di̇lek Olğun Erdi̇kmen, Esma Yildar, Asli Eki̇ci̇, Murat Şaroğlu, Bülent Eki̇z

Turkish Journal of Veterinary & Animal Sciences

In older patients, it is important to minimise anaesthesia-related deaths and complications. In this study, 2 separate anaesthesia inductions were evaluated with respect to their effects on heart rate, respiratory rate, pulse oximetry data, intraocular pressure, and body temperature. A total of 22 dogs were evaluated and 2 separate anaesthesia groups were formed. Propofol (6 mg/kg) was administered to group G1 via a slow intravenous (IV) injection. In group G2, diazepam (0.5 mg/kg) was first administered via an IV injection, followed immediately by alfentanil (40 µg/kg), administered via a slow IV route. Each parameter was recorded prior to anaesthesia (T_0), …

Factors Affecting Colostrum Quality Of Ewes And Immunostimulation, Özge Yilmaz, Güven Kaşikçi

Turkish Journal of Veterinary & Animal Sciences

Maternal antibodies play a major role in the development of the immune system of a young animal. Ideally, the transmission of maternal immunity to the foetus occurs in the uterus. However, in ruminants, as there is no maternal antibody transfer from the mother to her young by way of the uterus, the antibodies present in the colostrum are a vital necessity for newborn ruminants. After birth, an unhealthy neonatal period for the young animal and an unhealthy puerperal period for the mother can cause significant financial losses. In animal husbandry, due to the budget allocated for the treatment of diseases …

Glycohistochemistry Of The Lateral Tympanic Membrane In The Syrinx Of The Denizli Cock, Nazan Keski̇n, Pinar İli̇

Turkish Journal of Veterinary & Animal Sciences

The Denizli cock is a special race that has harmonious long crowing. In this study, the syrinx of the Denizli cock was studied by using glycohistochemical analyses. Paraffin sections were stained with Alcian blue (AB) at pH 1 and pH 2.5 for demonstration of sulfated and carboxylated carbohydrates, respectively. At AB-pH 1, the lateral tympanic membrane (LTM) and also the medial tympanic membrane (MTM) exhibited a weak reactivity, whereas they were stained intensely at AB-pH 2.5. The frozen sections were incubated with 5 digoxigenin-labeled lectins for lectin histochemistry: peanut agglutinin, Maackia amurensis leucoagglutinin, Galanthus nivalis agglutinin, Datura stramonium agglutinin, and …

The Effect Of Electron Beam Irradiation On Β-Glucan Content, X-Ray Diffraction Of Starch, Protein Subunit Patterns, And In Vivo Digestibility Of Barley Grain In Cockerels, Parvin Shawrang, Ali Asghar Sadeghi, Behnam Ghorbani

Turkish Journal of Veterinary & Animal Sciences

This study was carried out to evaluate the effect of electron beam radiation on the chemical composition, the \beta-glucan content, the water extract viscosity, the crystallinity of starch, the patterns of protein subunits, and the in vivo digestibility of barley grain. Barley samples were irradiated at doses of 10, 15, 20, 25, and 30 kGy under the electron beam. In a completely randomized design, cockerels were fed raw or irradiated samples to determine the digestibility of crude protein and gross energy. Irradiation had no effect on the total contents of protein, starch, and \beta-glucan. At doses of 10, 15, 20, …

Acute Toxicity Of Diazinon And Its Effects On Hematological Parameters In The Indian Carp, Cirrhinus Mrigala (Hamilton), Abdul Rauf, Naeemuddin Arain

Turkish Journal of Veterinary & Animal Sciences

Diazinon is a commonly used pesticide and its existence in the fresh water reservoirs of Pakistan has been reported by some authors. A semistatic experiment was conducted to find out the acute toxicity of diazinon as an aquatic pollutant on some hematological parameters of Indian carp (Cirrhinus mrigala). The 1, 24, 48, 72, and 96 h LC50 values of diazinon for Indian carp were estimated as 17.32 mg/L, 15.39 mg/L, 12.64 mg/L, 10.98 mg/L, and 8.15 mg/L respectively. A significant increase in the number of dead fish was observed as the concentration of diazinon and exposure time increased (P < 0.05). The results after acute exposure to 8.15 mg/L of diazinon for 96 h showed that compared to the control fish, the total erythrocytes, leukocytes, hemoglobin, and hematocrit values decreased significantly (P < 0.05) in exposed fish. The mean corpuscular volume and mean corpuscular hemoglobin increased significantly (P < 0.05), while the mean corpuscular hemoglobin concentration of both groups remained unchanged during the study. In conclusion, acute exposure to LC50 values of diazinon induced hematological alterations in Indian carp and offers a tool to evaluate toxicity derived alterations.

Prevalence And Antibiotic Resistance Of Vancomycin-Resistant Enterococci In Animal Originated Foods, Fi̇gen Çeti̇nkaya, Tülay Elal Muş, Gül Ece Soyutemi̇z, Recep Çibik

Turkish Journal of Veterinary & Animal Sciences

A total of 270 animal-originated foods purchased from markets, including milk and dairy products, fresh and processed meat products, and poultry and poultry products, were analysed to determine the prevalence of vancomycin-resistant enterococci (VRE). VRE were isolated from 12 out of 270 samples (4.4%): 6 (6%) from fresh meat and meat products and 6 (8.6%) from poultry and poultry products. VRE strains were identified as Enterococcus faecium (6 strains), E. avium (4 strains), E. durans (1 strain) and E. gallinarum (1 strain). Among these strains, 11 had high levels of vancomycin resistance (2 E. faecium strains had minimum inhibitory concentrations …

Rhodotorula Minuta Fungemia In A Ewe Lamb, C. G. Chitko-Mckown, K. A. Leymaster, M. P. Heaton, D. D. Griffin, J. K. Veatch, S. A. Jones, M. L. Clawson

School of Veterinary and Biomedical Sciences: Faculty Publications

An 8-month-old crossbred ewe, normal upon physical examination, was humanely euthanized for tissue collection. After approximately 3 weeks in tissue culture, fungi began budding out of cells obtained from the choroid plexus. After an additional 3 weeks, budding was observed in kidney cell cultures and eventually in monocyte cultures as well. Serum from the lamb was submitted to the Veterinary Diagnostic Laboratory at Colorado State University for fungal diagnosis and was found negative for Aspergillus, Blastomyces, Coccidioidomycosis and Histoplasmosis. DNA was isolated from fungi collected from tissue culture supernatants and used in a set of pan-fungal PCR assays with …

Interferon Inducible Protein Ifi35 Negatively Regulates Rig-I Antiviral Signaling And Supports Vesicular Stomatitis Virus Replication, Anshuman Das, Phat X. Dinh, Debasis Panda, Asit K. Pattnaik

School of Veterinary and Biomedical Sciences: Faculty Publications

In a genome-wide siRNA screen, we recently identified the interferon (IFN) inducible protein 35 (IFI35, also known as IFP35) as a factor required for VSV infection. Studies reported here were conducted to further understand the role and requirement of IFI35 in VSV infection. Consistent with the siRNA screening data, we found that depletion of IFI35 led to reduced VSV replication at the level of viral gene expression. Although no direct interaction of IFI35 with the viral replication machinery was observed, we found that IFI35 negatively regulated the host innate immune response and rescued poly(I:C)-induced inhibition of VSV replication. Promoter-driven reporter …

Sequence-Optimized And Targeted Double-Stranded Rna As A Therapeutic Antiviral Treatment Against Infectious Myonecrosis Virus In Litopenaeus Vannamei, J. Dustin Loy, Duan S. Loy, Mark A. Mogler, Bruce Janke, Kurt Kamrud, D. L. Hank Harris, Lyric C. Bartholomay

School of Veterinary and Biomedical Sciences: Faculty Publications

Infectious myonecrosis virus (IMNV) is a significant and emerging pathogen that has a tremendous impact on the culture of the Pacific white shrimp Litopenaeus vannamei. IMNV first emerged in Brazil in 2002 and subsequently spread to Indonesia, causing large economic losses in both countries. No existing therapeutic treatments or effective interventions currently exist for IMNV. RNA interference (RNAi) is an effective technique for preventing viral disease in shrimp. Here, we describe the efficacy of a double-stranded RNA (dsRNA) applied as an antiviral therapeutic following virus challenge. The antiviral molecule is an optimized dsRNA construct that targets an IMNV sequence …

Bovine Herpes Virus 1 (Bhv-1) And Herpes Simplex Virus Type 1 (Hsv-1) Promote Survival Of Latently Infected Sensory Neurons, In Part By Inhibiting Apoptosis, Clinton Jones

School of Veterinary and Biomedical Sciences: Faculty Publications

α-Herpesvirinae subfamily members, including herpes simplex virus type 1 (HSV-1) and bovine herpes virus 1 (BHV-1), initiate infection in mucosal surfaces. BHV-1 and HSV-1 enter sensory neurons by cell-cell spread where a burst of viral gene expression occurs. When compared to non-neuronal cells, viral gene expression is quickly extinguished in sensory neurons resulting in neuronal survival and latency. The HSV-1 latency associated transcript (LAT), which is abundantly expressed in latently infected neurons, inhibits apoptosis, viral transcription, and productive infection, and directly or indirectly enhances reactivation from latency in small animal models. Three anti-apoptosis genes can be substituted for LAT, which …

Gastroscopic Evaluation Of Gastric Ulcer Syndrome In Sport Horses With Poor Performance, Mehmet Alper Çeti̇nkaya, Alper Demi̇rutku, Mahi̇r Kaya

Turkish Journal of Veterinary & Animal Sciences

Gastric ulceration is common in performance horses. More than 90% of thoroughbred horses in the training season and approximately 60% of racing horses from other disciplines have gastric ulcers. Excessive secretion of gastric acid, impairment of gastric mucosal blood flow, weakening of prostaglandin E or the gastric mucus/bicarbonate layer, and gastric emptying disorders are important factors in the onset of ulceration. In this study, 12 horses with poor performance were evaluated using gastroscopy following clinical examinations. Gastroscopy revealed ulceration in 5 horses and ulcerative lesions in 7. A daily dose of 4 mg/kg omeprazole was administered orally for 4 weeks …

Optimization Of Feline Adipose-Derived Multipotent Stromal Cell Isolation And Canine Cranial Cruciate Ligament Regeneration With Intra-Articular Adipose-Derived Multipotent Stromal Cells, Nan Zhang

LSU Doctoral Dissertations

Adult multipotent stromal cells (MSCs) have become popular within veterinary sciences for direct administration and tissue regeneration due to their differentiation, trophic and immunosuppressive properties. However, current isolation and expansion techniques provide a heterogeneous population with other types of cells, which may affect the efficiency and efficacy of treatments. The progenitor properties and function need to be further evaluated in vitro prior to in vivo application. The first part of this dissertation was to identify the optimal MSC source for general canine orthopedic applications such as intra-articular injection and joint tissue regeneration. Based on side-by-side comparisons of cell doublings, colony …